Clinical trials · Raleigh–Durham, NC
Chronic kidney disease clinical trials in Raleigh–Durham
We’re tracking 21 recruiting chronic kidney disease studies with a site in or near Raleigh–Durham — including Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies near Raleigh–Durham
- NCT05334069Recruiting
Blood test study for early cancer detection in patients
This study collects blood from people with cancer and people without cancer (or with possible cancer) to test whether new blood tests can detect cancer earlier. Your blood samples help researchers evaluate how well these tests work.
Cary, North CarolinaAges 40–75 - NCT06001827Recruiting
Study of a wrap to help new dialysis access points heal
This trial tests a special wrap placed around a new arm access point for dialysis (called an AV fistula) to see if it helps the access stay healthy and work better. It is for people who need a new AV fistula for kidney dialysis.
Raleigh, North CarolinaAges 18 years+ - NCT06742723RecruitingPhase 3
Study of baxdrostat and dapagliflozin for kidney disease and high blood pressure
This trial tests if combining baxdrostat with dapagliflozin helps protect kidney function and reduce heart risks in people with chronic kidney disease and high blood pressure. It's for adults who are already taking standard blood pressure medications.
Raleigh, North CarolinaAges 18 years+ - NCT07662135RecruitingPhase 3
A study of elecoglipron for type 2 diabetes with kidney problems
This trial tests a new medicine called elecoglipron to see if it helps control blood sugar in people with type 2 diabetes who also have reduced kidney function. You would continue taking your current SGLT2i medication (like dapagliflozin).
Raleigh, North CarolinaAges 18 years+ - NCT06283966RecruitingPhase 3
Triple inhaler for COPD with heart risk
This study tests a triple-combination inhaler (budesonide, glycopyrronium, and formoterol) to see if it can help protect the heart and lungs in people with COPD who also have heart problems or high risk for them.
Raleigh, North CarolinaAges 40–80 - NCT04671771Recruiting
Testing a new graft for hemodialysis access in kidney failure
This study tests whether an “AV graft” implant works safely and well for people with end-stage kidney disease who need hemodialysis. It may help your dialysis access last and work better, compared with current expectations for AV grafts.
Raleigh, North CarolinaAges 18–90 - NCT06906640Recruiting
Improving Kidney Care for People with Type 2 Diabetes
This study tests a program to help primary care doctors better screen and manage kidney problems in people with type 2 diabetes. It aims to see if using recommended medicines can slow kidney disease and improve health.
Durham, North CarolinaAges 18 years+ - NCT06906627Recruiting
Improving kidney screening for people with diabetes
This study helps people with type 2 diabetes get the right kidney tests to catch kidney problems early. Your doctor will check your kidney health through a simple blood and urine test.
Durham, North CarolinaAges 18 years+ - NCT04741646RecruitingPhase 2
Ferric citrate for kids with chronic kidney disease
This Phase 2 study tests ferric citrate, a medicine that helps control phosphate and iron balance, in children with chronic kidney disease. It may help slow problems related to kidney disease by improving lab measures like phosphate levels.
Durham, North CarolinaAges 6–18 - NCT05832229RecruitingPhase 2
Studying rosuvastatin to slow liver scarring in cirrhosis
This Phase 2 trial tests whether rosuvastatin (a cholesterol-lowering medicine) can improve how well the liver functions and slow worsening scarring in people with cirrhosis. It also checks for side effects and safety.
Durham, North CarolinaAges 18–75 - NCT07355296RecruitingPhase 2
Testing BI 764198 in adults and teens with kidney disease
This study tests an investigational drug (BI 764198) in adults and teens with different types of kidney disease. The goal is to see if the drug can help slow kidney damage. You may be able to join if your kidney function is at a certain level, you are on stable blood pressure medications, and you haven't had recent strong immune treatments.
Durham, North CarolinaAges 12 years+ - NCT05917522RecruitingPhase 2
Biomarker-guided changes to anti-rejection medicines after kidney transplant
This Phase 2 study looks at whether blood test “biomarkers” can guide safely changing anti-rejection medicines after an ABO-compatible kidney transplant. It may help some people reduce certain medicines while keeping the new kidney protected from rejection.
Durham, North CarolinaAges 18–70 - NCT06830629RecruitingPhase 2
MZE829 for APOL1 kidney disease
This trial tests an experimental drug called MZE829 for people with kidney disease linked to the APOL1 gene. It aims to see if the drug can help protect kidney function.
Durham, North CarolinaAges 18–68 - NCT05793138Enrolling by invitation
Care model for older adults on dialysis at home
This trial tests a geriatric (older-adult) care approach to support people age 55+ who receive dialysis while living in the community. It may help improve how care is coordinated for older adults, including those with mild to moderate memory or thinking problems.
Durham, North CarolinaAges 55 years+ - NCT06055608RecruitingPhase 2
Improving kidney transplant outcomes in teens and young adults
This trial tests a new approach to help teenagers and young adults keep their first kidney transplant working well. It looks at how to improve long-term success by carefully managing the immune system around the time of transplant.
Durham, North CarolinaAges 13–20 - NCT06907147Recruiting
Renal denervation for uncontrolled high blood pressure
This trial tests a procedure called renal denervation to lower blood pressure in people whose medication isn't enough. It uses a special catheter to calm nerves near the kidneys that may be overactive.
Chapel Hill, North CarolinaAges 18–80 - NCT04334707Recruiting
Study kidney damage in people with long-term diabetes
This study is looking at different kidney health patterns in people with diabetes, especially diabetic kidney disease and people who have not developed kidney damage despite long-term diabetes. It may help researchers understand why kidney problems happen—and what protective factors might prevent them.
Chapel Hill, North CarolinaAges 18 years+ - NCT05828823Recruiting
Two-times-a-week dialysis for new patients
This study tests whether starting dialysis at twice a week, instead of the usual three times, is safe and effective for people who still have some kidney function. If the kidneys still make urine and clear waste, being on dialysis less often may maintain that function longer.
Chapel Hill, North CarolinaAges 18 years+ - NCT05997875Recruiting
Learning about dialysis access options
This study tests a new way to teach people about hemodialysis and the access (the spot in your arm or leg where the dialysis machine connects). It is for people with advanced kidney disease who are considering hemodialysis and want to learn about their options for vascular access.
Chapel Hill, North CarolinaAges 18 years+ - NCT06823115Enrolling by invitation
Worldwide study of kidney injury in newborns
This study looks at how common acute kidney injury is in newborns in the intensive care unit. It helps doctors understand which babies are at risk and how to prevent kidney problems.
Chapel Hill, North CarolinaAges birth–2 weeks - NCT06902558RecruitingPhase 2
Study of ABBV-CLS-628 for adults with polycystic kidney disease
This trial tests a new drug, ABBV-CLS-628, for people with autosomal dominant polycystic kidney disease (ADPKD). The goal is to see if it slows kidney function decline and is safe to use.
Chapel Hill, North CarolinaAges 18–55
Hear when a new Chronic kidney disease trial opens near Raleigh–Durham, NC
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Chronic kidney disease trials in other cities
Where these studies are running near Raleigh–Durham
Institutions with a site for the recruiting chronic kidney disease studies listed above.
- University of North Carolina at Chapel Hill · 5 studies
- Duke University Medical Center · 4 studies
- Research Site · 4 studies
- Duke University · 3 studies
- WakeMed Health & Hospitals · 2 studies
- Duke
- Duke Liver Center
- Durham VA Medical Center
What taking part in a chronic kidney disease study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting chronic kidney disease studies in North Carolina.
Common questions
- Are there chronic kidney disease clinical trials near Raleigh–Durham?
- Yes. We're currently tracking 21 recruiting chronic kidney disease studies with a site near Raleigh–Durham, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a chronic kidney disease study near Raleigh–Durham?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Raleigh–Durham to take part?
- Not necessarily. These studies have a site near Raleigh–Durham, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a chronic kidney disease trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New chronic kidney disease studies open near Raleigh–Durham regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.