Clinical trials
Chronic kidney disease clinical trials
A gradual loss of kidney function over time. We’re tracking 571 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06531824RecruitingPhase 3
Heart and kidney protection study for chronic kidney disease
This study tests a new medicine (BI 690517) combined with empagliflozin to see if it can help protect the heart and kidneys in people with chronic kidney disease. It may slow down kidney disease progression and reduce heart risks.
Huntsville, AlabamaAges 18 years+ - NCT07496177RecruitingPhase 2
HTD1801 for kidney function in diabetes and kidney disease
This trial tests whether a new drug, HTD1801, can protect or improve kidney function in people with type 2 diabetes and chronic kidney disease. It may help slow kidney damage and reduce protein in urine.
Weifang, ShandongAges 18–75 - NCT06435858RecruitingPhase 2
SGLT2 inhibitor for calcium and magnesium in ADPKD
This study tests whether a medicine called an SGLT2 inhibitor (a type of diabetes drug) can help control calcium and magnesium levels in people with a genetic kidney disease called ADPKD. The goal is to see if it improves kidney health over a short period.
Zurich, Canton of ZurichAges 18–75 - NCT07454174Recruiting
Study of a dietary program for polycystic kidney disease
This study tests a special medical food (Ren-Nu) to see if it helps with metabolism and kidney health in people with ADPKD. You would follow a dietary program and attend online classes.
Cleveland, OhioAges 18 years+ - NCT04939935RecruitingPhase 3
Metformin to slow kidney decline in adults with polycystic kidneys
This Phase 3 study tests whether taking metformin can slow the decline of kidney function in adults with autosomal dominant polycystic kidney disease (ADPKD). You may be eligible if you have ADPKD and signs that your kidneys are starting to decline faster than expected.
Gosford, New South WalesAges 18–70 - NCT06051058Recruiting
App for managing health after hospital discharge
This study tests a smartphone app designed to help people with multiple health conditions manage their care after leaving the hospital. It may help you feel more supported and avoid confusion during the transition from hospital to home.
Boston, MassachusettsAges 55 years+ - NCT07013344Recruiting
Link between NT-proBNP and heart artery disease
This study looks at a blood test called NT-proBNP to see if it can help predict how much blockage is in the heart's arteries. It may help doctors better understand heart disease risk.
Milan, ItalyAges 18 years+ - NCT07690202Recruiting
Living with kidney disease without dialysis or transplant
This study looks at the experiences of women of childbearing age who have chronic kidney disease but are not on dialysis or have not had a kidney transplant. The goal is to understand how the disease affects their lives.
CaenAges 18 years+ - NCT03979534Recruiting
Protecting Kidneys With a Low-Protein Diet
This study tests whether a step-by-step low-protein diet can help protect your kidneys if you have advanced chronic kidney disease (stages 4 or 5) or stage 3 that is getting worse quickly. The goal is to see if this diet approach can slow down kidney damage.
La FlècheAges 18 years+ - NCT07106879Recruiting
Pre-screening for future metabolic and psychiatric studies
This study does not test a new treatment. It is a pre-screening program to see if you might qualify for future clinical trials on metabolic conditions (like diabetes or weight issues) or psychiatric health (like depression or anxiety). You will be asked some questions and may do some basic health checks to see which future trials could be a good fit for you.
Brooklyn, New YorkAges 18 years+ - NCT04626167RecruitingEarly Phase 1
Testing a bladder transplant done with a kidney transplant
This early-phase study is testing a combined bladder and kidney transplant approach for people whose bladder problems damage the kidneys. The goal is to see if this treatment can improve bladder and kidney outcomes and be done safely.
Rochester, MinnesotaAges 1–60 - NCT07722585RecruitingPhase 1
New tablet study: absorption and food effects
This study tests a new form of the drug nurandociguat tablet to see how well it is absorbed compared to the old tablet, and whether food changes how it works. Healthy volunteers are needed to take the tablets and have their blood levels checked.
BerlinAges 18–58 - NCT07481526Recruiting
Chronic kidney disease registry study
This study is collecting information from people with chronic kidney disease (CKD) to understand how the disease progresses over time. It does not test any new treatments, so you keep your usual care.
Anning, Yunnan - South RegionAges Any age - NCT06300788Recruiting
Pyrophosphate study in children with kidney disease
This study looks at a natural chemical in the body called pyrophosphate (PPi) in children with chronic kidney disease. It aims to understand how kidney problems affect this chemical, which is important for bone health. The study needs kids with different kidney stages, including those on dialysis, with a transplant, or even healthy kids having surgery for comparison.
Nice, Alpes-MaritimesAges birth–18 years - NCT05204212Recruiting
Heart procedure to close an atrial clot risk pouch in kidney failure
This trial tests a heart procedure that closes a part of the heart called the left atrial appendage to help prevent stroke in people with an irregular heartbeat (atrial fibrillation) and very advanced kidney disease. It’s mainly for patients who can take the needed blood-thinner medicines and who do not already have a clot in that pouch.
Lübeck, Schleswig-HolsteinAges 18 years+ - NCT04819217Recruiting
Probiotics and a toxin binder to slow chronic kidney disease
This trial studies an oral product (a “uremic toxin” absorber) plus probiotics to help slow the progression of chronic kidney disease. It may help by lowering harmful gut-related substances that can build up when kidney function is reduced.
TaipeiAges 20 years+ - NCT06802978Recruiting
Lipid test in diabetic and non-diabetic kidney patients
This study checks cholesterol and fat levels in the blood of people with chronic kidney disease, comparing those with and without diabetes. It aims to understand how kidney disease affects lipid profiles.
SohagAges 21 years+ - NCT06463236Recruiting
Study of anemia management in dialysis patients
This study is testing a new way to manage anemia (low red blood cells) in people on long-term dialysis. It aims to improve how doctors treat this common issue.
Chengdu, SichuanAges 18 years+ - NCT06847139Recruiting
Zinc vs. folic acid for high homocysteine in kidney dialysis
This trial tests whether zinc supplements can lower high homocysteine levels better than folic acid in people with chronic kidney disease who are on hemodialysis. It aims to find a simple, safe way to help protect your heart and blood vessels.
ChittagongAges Any age - NCT07182942RecruitingPhase 4
Study of Xiqing and Probiotics for Chronic Kidney Disease
This trial tests if taking Xiqing (a Chinese herbal product) and probiotics together can help people with chronic kidney disease (CKD) by improving gut health and making their medication work better. It is for patients with moderate to advanced CKD who do not need dialysis yet.
Wuhan, HubeiAges 18–75 - NCT07203287RecruitingPhase 4
Comparing muscle relaxants in kidney disease patients during surgery
This trial compares two muscle relaxants, rocuronium and cisatracurium, to see which causes fewer complications in people with chronic kidney disease (not on dialysis) who need general anesthesia. If you have kidney disease and are having surgery that requires a breathing tube, this study may help determine the safer drug for you.
Galveston, TexasAges 18–80 - NCT07045064Recruiting
Exercise during dialysis for heart health
This study compares two types of exercise (aerobic vs. resistance training) done during hemodialysis sessions, and looks at how they affect a blood test related to heart disease risk.
Cairo, Select StateAges 40–60 - NCT07283926Enrolling by invitation
Restorative meals at home for older adults on dialysis
This trial tests if providing supportive meals at home can improve nutrition and health for older adults (60+) with chronic kidney disease who are on hemodialysis and from low-income, food-insecure households in Malaysia.
Kuala Lumpur, Kuala LumpurAges 60 years+ - NCT07333313Recruiting
Study of oral medicine and probiotics for kidney disease in diabetes
This trial tests if an oral medication that absorbs toxins plus probiotics can reduce inflammation and slow kidney damage in people with diabetes-related kidney disease (DKD). It may help those with mild to severe kidney function loss.
Taipei, TaiwanAges 20 years+
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Common questions
- Are there clinical trials for chronic kidney disease?
- Yes. Clin2 currently lists 571 recruiting chronic kidney disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic kidney disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic kidney disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.