Clinical trials
Chronic kidney disease clinical trials
A gradual loss of kidney function over time. We’re tracking 559 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06396416RecruitingPhase 4
Obesity management after kidney transplant
This study tests whether a weight loss medication (semaglutide) can help manage obesity in people who have had a kidney transplant or are at high risk. It aims to improve health outcomes and prevent further kidney decline.
London, OntarioAges 18 years+ - NCT05726526Recruiting
Phone app monitoring to help people with advanced kidney disease
This study tests a phone app (with check-ins on things like blood pressure and weight) to help prevent complications in people with advanced chronic kidney disease. You may be a good match if you’re high risk and can actively measure and share your health data with a kidney care team.
Winnipeg, ManitobaAges 18 years+ - NCT05397392Recruiting
Diagnosis and treatment plan for heart–kidney problems
This study looks at the best way to diagnose and treat different types of heart-and-kidney problems that happen together. It may help you (or your caregiver) get the right classification and treatment approach based on how your heart and kidneys are affected.
NanjingAges 18 years+ - NCT05865691Recruiting
Study blood and organ changes in chronic liver disease
This study looks at how blood clotting, inflammation, and blood vessels change in people with chronic liver disease or cirrhosis. Your blood tests may help researchers understand what drives the disease and could guide future care.
ClichyAges 18 years+ - NCT07661940RecruitingPhase 2
SP16 for kidney protection during heart surgery
This trial tests a drug called SP16 to see if it can prevent acute kidney injury in people with chronic kidney disease who are having elective heart surgery with a heart-lung machine. It aims to help preserve kidney function after surgery.
Erlangen, BavariaAges 18 years+ - NCT06621264Recruiting
Exercise study to improve walking in kidney and artery disease
This trial tests whether a supervised exercise program can help people with chronic kidney disease and peripheral artery disease walk better and feel stronger. It aims to improve mobility and quality of life.
Ferrara, ItalyAges 18–80 - NCT06409624Recruiting
Biomarkers and kidney decline in pulmonary hypertension
This study looks at how certain blood markers (biomarkers) relate to kidney function decline in people with pulmonary hypertension. Participants will have blood and urine tests, and their kidney function will be tracked over time.
Bad Nauheim, HesseAges 18 years+ - NCT06243068Enrolling by invitation
Supporting decisions about kidney care without dialysis
This study helps people with advanced chronic kidney disease explore their care options, including the choice to manage without dialysis. It provides support and information to help you and your family make a decision that fits your values.
San Francisco, CaliforniaAges 65 years+ - NCT07651436Recruiting
Depression screening in patients on kidney dialysis
This study tests whether nurses can effectively screen for depression in patients receiving regular kidney dialysis treatment. The goal is to find the best way to identify depression early so patients can get help.
AnnecyAges 18 years+ - NCT07288905Recruiting
Exercise with blood flow restriction for healthy people and CKD patients
This study tests if combining exercise with blood flow restriction training (BFRT) is safe and helpful for healthy adults and people with chronic kidney disease (CKD). It aims to improve strength and health without heavy weights.
TainanAges 20–85 - NCT07153939Recruiting
Study of a new device to create dialysis access
This trial tests a new device called the Velocity pAVF System that creates a connection between a vein and artery in your arm for hemodialysis. If you need dialysis now or within the next 6 months, this could be a new option for you.
Dothan, AlabamaAges 18–80 - NCT07026539RecruitingPhase 4
Finerenone for heart and kidney health in type 2 diabetes
This trial tests whether adding finerenone to your current diabetes medications can better protect your heart and kidneys. It is for people with type 2 diabetes who already take an SGLT2 inhibitor and an ACE inhibitor or ARB.
Aarhus NAges 18 years+ - NCT06933472RecruitingPhase 3
Study of a new phosphate binder for dialysis patients
This trial tests a new drug called AP301 to lower high phosphate levels in people on dialysis. It's designed to help control phosphate, which can be hard to manage with diet and current medications.
Granada Hills, CaliforniaAges 12 years+ - NCT06823115Enrolling by invitation
Worldwide study of kidney injury in newborns
This study looks at how common acute kidney injury is in newborns in the intensive care unit. It helps doctors understand which babies are at risk and how to prevent kidney problems.
Birmingham, AlabamaAges birth–2 weeks - NCT05189925RecruitingPhase 1
Correcting a missing immune enzyme using an mRNA cell therapy
This early-phase trial tests whether an mRNA-based treatment can correct a key immune problem in people with chronic granulomatous disease (CGD). It may help your immune cells work better against infections, but this is mainly to check safety and early signs of benefit.
Bethesda, MarylandAges 18–75 - NCT07496177RecruitingPhase 2
HTD1801 for kidney function in diabetes and kidney disease
This trial tests whether a new drug, HTD1801, can protect or improve kidney function in people with type 2 diabetes and chronic kidney disease. It may help slow kidney damage and reduce protein in urine.
Weifang, ShandongAges 18–75 - NCT07454174Recruiting
Study of a dietary program for polycystic kidney disease
This study tests a special medical food (Ren-Nu) to see if it helps with metabolism and kidney health in people with ADPKD. You would follow a dietary program and attend online classes.
Cleveland, OhioAges 18 years+ - NCT07013344Recruiting
Link between NT-proBNP and heart artery disease
This study looks at a blood test called NT-proBNP to see if it can help predict how much blockage is in the heart's arteries. It may help doctors better understand heart disease risk.
Milan, ItalyAges 18 years+ - NCT06051058Recruiting
App for managing health after hospital discharge
This study tests a smartphone app designed to help people with multiple health conditions manage their care after leaving the hospital. It may help you feel more supported and avoid confusion during the transition from hospital to home.
Boston, MassachusettsAges 55 years+ - NCT04939935RecruitingPhase 3
Metformin to slow kidney decline in adults with polycystic kidneys
This Phase 3 study tests whether taking metformin can slow the decline of kidney function in adults with autosomal dominant polycystic kidney disease (ADPKD). You may be eligible if you have ADPKD and signs that your kidneys are starting to decline faster than expected.
Gosford, New South WalesAges 18–70 - NCT07690202Recruiting
Living with kidney disease without dialysis or transplant
This study looks at the experiences of women of childbearing age who have chronic kidney disease but are not on dialysis or have not had a kidney transplant. The goal is to understand how the disease affects their lives.
CaenAges 18 years+ - NCT03979534Recruiting
Protecting Kidneys With a Low-Protein Diet
This study tests whether a step-by-step low-protein diet can help protect your kidneys if you have advanced chronic kidney disease (stages 4 or 5) or stage 3 that is getting worse quickly. The goal is to see if this diet approach can slow down kidney damage.
La FlècheAges 18 years+ - NCT07106879Recruiting
Pre-screening for future metabolic and psychiatric studies
This study does not test a new treatment. It is a pre-screening program to see if you might qualify for future clinical trials on metabolic conditions (like diabetes or weight issues) or psychiatric health (like depression or anxiety). You will be asked some questions and may do some basic health checks to see which future trials could be a good fit for you.
Brooklyn, New YorkAges 18 years+ - NCT04626167RecruitingEarly Phase 1
Testing a bladder transplant done with a kidney transplant
This early-phase study is testing a combined bladder and kidney transplant approach for people whose bladder problems damage the kidneys. The goal is to see if this treatment can improve bladder and kidney outcomes and be done safely.
Rochester, MinnesotaAges 1–60
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Common questions
- Are there clinical trials for chronic kidney disease?
- Yes. Clin2 currently lists 559 recruiting chronic kidney disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic kidney disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic kidney disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.