Clinical trials
Chronic kidney disease clinical trials
A gradual loss of kidney function over time. We’re tracking 571 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07662135RecruitingPhase 3
A study of elecoglipron for type 2 diabetes with kidney problems
This trial tests a new medicine called elecoglipron to see if it helps control blood sugar in people with type 2 diabetes who also have reduced kidney function. You would continue taking your current SGLT2i medication (like dapagliflozin).
Peoria, ArizonaAges 18 years+ - NCT07725497RecruitingPhase 2
Luspatercept for anemia from chronic kidney disease
This trial tests a drug called luspatercept to see if it can raise hemoglobin levels in people with anemia caused by chronic kidney disease. It's for those whose current treatments aren't working well or who cannot use them.
Basking Ridge, New JerseyAges 18 years+ - NCT07317310Recruiting
Joint health and weight loss study for knee osteoarthritis patients
This trial tests a joint health program for people with knee osteoarthritis and a BMI of 27 or higher. The goal is to see if it can improve knee pain and help with weight management.
Taipei, TaiwanAges 18–75 - NCT03524222Recruiting
Home hospital care for adults after sudden illness
This trial tests whether certain adults can safely receive hospital-level care at home instead of staying in the hospital, using a home care team. It may help you recover in your own home if your condition fits their plan and you have support at home.
Boston, MassachusettsAges 18 years+ - NCT03929900Recruiting
Study follow-up for kidney disease in adults (non-dialysis)
This study follows adults with chronic kidney disease who are not on dialysis. It aims to better understand kidney health and test what care or monitoring might help over time.
Seoul, Jongno-guAges 45–79 - NCT04330729Recruiting
Aspirin effect on blood clotting in kidney disease
This study checks how aspirin (also called salicylate) affects how platelets work, which helps blood clot. It involves people with advanced chronic kidney disease who are treated with Aranesp, and it may help guide safer care.
RoskildeAges 18–85 - NCT04381143RecruitingPhase 4
Aspirin to prevent problems in people on dialysis
This trial studies whether taking aspirin can reduce heart and clot-related complications in adults receiving long-term dialysis. It may help by improving blood clotting behavior, but it also requires that aspirin is safe for you.
Fuzhou, FujianAges 18 years+ - NCT04500665RecruitingPhase 2
Colchicine for kidney-related heart inflammation
This Phase 2 trial tests whether colchicine can reduce inflammation and improve heart function in people with kidney disease and a certain type of heart problem. If you qualify, you’ll be closely monitored for side effects and lab changes.
Boston, MassachusettsAges 21–80 - NCT04522765Recruiting
Tracking daily blood pressure patterns in people at high heart risk
This study measures how your blood pressure changes across the day in people at higher risk of heart and blood vessel disease. It may help researchers understand why blood pressure patterns vary, which could guide better prevention or care.
EdinburghAges 18–90 - NCT04592640RecruitingEarly Phase 1
Amniotic stem cell treatment for calciphylaxis
This early-phase study tests a stem cell therapy made from amniotic (placenta) tissue for people with calciphylaxis. If you qualify, the goal is to see whether this treatment is safe and potentially helpful for this rare, painful condition.
Nanjing, JiangsuAges 18–75 - NCT04759274Recruiting
Personalized water pill dosing support for kidney and fluid overload
This trial tests a decision-support tool to help your care team safely adjust water pills (“diuretics”) when you have kidney disease and fluid buildup. It may help reduce swelling by guiding dosing using your home weight and blood pressure.
Dallas, TexasAges 18 years+ - NCT04848636Recruiting
Sodium MRI scan to study heart salt changes in kidney disease
This trial uses a special MRI scan (called sodium MRI) to measure salt (sodium) in the heart. It compares people with chronic kidney disease (including those on hemodialysis) to healthy volunteers to understand how kidney disease may affect the heart.
London, OntarioAges 18 years+ - NCT04984226RecruitingPhase 2
Sodium bicarbonate for kidney disease energy and acidity
This trial studies whether taking sodium bicarbonate changes “energy” in cells and improves metabolic acidosis (an acid build-up) in people with moderate-to-severe chronic kidney disease. You may be able to join if your kidney function and blood bicarbonate levels fit their targets and you meet safety rules.
Sacramento, CaliforniaAges 21–85 - NCT05018845RecruitingPhase 1
Testing a donated stem cell treatment for chronic kidney disease
This early study (Phase 1) tests whether an intravenously given, donated stem cell product is safe for people with chronic kidney disease. It mainly looks at side effects and whether the treatment can be given without harming you.
St John'sAges Any age - NCT05056701Recruiting
Checking early care for kidney disease after pre-eclampsia
This study looks at how to predict and diagnose chronic kidney disease (long-term kidney damage) in people who had pre-eclampsia during pregnancy, including related serious conditions. It may help identify kidney problems earlier so care can start sooner.
AngersAges 18 years+ - NCT05090865Recruiting
Increase dietary potassium before dialysis
This study tests whether eating a higher-potassium diet is safe and helpful for people with early-to-moderate kidney failure who are not yet on dialysis. You may be asked to follow a specific diet plan and have blood tests to monitor potassium and other health markers.
Winnipeg, ManitobaAges 18 years+ - NCT05173714RecruitingPhase 2
Sit Less and Move More program for people with CKD
This Phase 2 study tests a program to help people with chronic kidney disease (CKD) sit less and move more, plus a medication (semaglutide) for those who qualify. It may help improve health and day-to-day activity while monitoring safety closely.
Stanford, CaliforniaAges 20 years+ - NCT05321368Recruiting
Program to help control blood pressure and support health equity
This study tests a program that combines clinic care, community support, and phone-based monitoring to help people better manage blood pressure and related health problems. It aims to reduce health differences between groups that have been affected more by preventable disease.
Washington D.C., District of ColumbiaAges 18 years+ - NCT05356325Recruiting
Testing FGF23 in anemia with and without kidney disease
This study looks at a blood hormone called FGF23 and whether it is linked to heart (cardiovascular) problems in people with anemia. It also compares people with anemia who do and do not have chronic kidney disease, which may help researchers understand risk and targets.
CórdobaAges 18–85 - NCT05359263RecruitingPhase 2
Dapagliflozin for kidney disease to improve heart structure
This Phase 2 study tests whether dapagliflozin can improve heart structure and function in people with chronic kidney disease (CKD). Dapagliflozin is a kidney-heart medicine that may affect how the heart changes over time, measured by heart scans.
CopenhagenAges 18 years+ - NCT05546099RecruitingPhase 3
Patient-guided blood pressure control in chronic kidney disease
This Phase 3 study tests whether a patient-driven plan for managing blood pressure can better control hypertension in people with chronic kidney disease (CKD). The goal is to see if this approach is safe and helps prevent health problems related to high blood pressure.
Iowa City, IowaAges 18 years+ - NCT05655325Recruiting
Exercise program to improve thinking in older adults with mild memory trouble
This study tests whether a supervised exercise plan can improve executive thinking (like planning and task control) in older adults with mild cognitive impairment. Researchers also look for brain changes using an MRI.
New York, New YorkAges 55 years+ - NCT05753020Recruiting
Kidney care planning tool for older adults with advanced kidney disease
This pilot study tests a “JumpStart” tool to help people with advanced kidney disease talk with their clinician about treatment choices in a way that matches their values. It may help you have clearer conversations about next steps before dialysis becomes necessary.
Seattle, WashingtonAges 75 years+ - NCT05858437Recruiting
Testing propionic acid to improve immune function in children with kidney failure
This study tests whether propionic acid can help the immune system work differently in children with advanced chronic kidney disease who receive regular dialysis. It may help regulate immune cells, aiming for better immune function while keeping you medically stable.
BerlinAges 12–20
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Common questions
- Are there clinical trials for chronic kidney disease?
- Yes. Clin2 currently lists 571 recruiting chronic kidney disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic kidney disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic kidney disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.