Clinical trials
Chronic kidney disease clinical trials
A gradual loss of kidney function over time. We’re tracking 571 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06578533RecruitingPhase 3
Keeping heart and kidney medications while controlling potassium
This trial tests a medication (SZC) that helps lower high potassium levels, so you can keep taking important heart and kidney drugs (RAASi/MRA). It is for people with heart failure and chronic kidney disease who have high potassium.
AlicanteAges 18 years+ - NCT06593392RecruitingPhase 2
Safety of difelikefalin for itching in teens on dialysis
This trial tests a drug called difelikefalin to see if it safely reduces moderate-to-severe itching in teenagers who are on hemodialysis. Itching is common in kidney disease, and this study aims to find a new treatment option.
ChengduAges 12–18 - NCT06607913Recruiting
Exercise after hospitalization for kidney patients
This study tests whether a personalized exercise program can help adults over 55 with chronic kidney disease regain strength and mobility after a hospital stay.
Aurora, ColoradoAges 55 years+ - NCT06624358Recruiting
Physical activity study for teens with chronic kidney disease
This study looks at physical activity in teens with chronic kidney disease (CKD) who are not yet on dialysis or have had a transplant. It aims to understand their current activity levels and how to help them stay active safely.
Philadelphia, PennsylvaniaAges 13–18 - NCT06631820Recruiting
A study of epicatechin for muscle health in advanced kidney disease
This trial tests whether a natural supplement called epicatechin can improve muscle health in people with advanced chronic kidney disease (CKD). You may be able to join if you have low kidney function and are not planning to start dialysis or have a kidney transplant in the next 4 months.
Huddinge, Stockholm CountyAges 60 years+ - NCT06642272RecruitingPhase 4
Comparing two diabetes drugs in real-world use
This trial compares two common diabetes medications, empagliflozin and dapagliflozin, to see which works better in everyday practice. It aims to find the best treatment option for patients with type 2 diabetes.
CopenhagenAges 18 years+ - NCT06671535Recruiting
Dialysis filter for itching in hemodialysis patients
This study tests a special type of dialysis filter (made of PMMA) to see if it can reduce severe itching and improve quality of life for people on long-term dialysis. If you have bothersome itching that standard treatment hasn't helped, this trial might be an option for you.
Saint PetersburgAges 18 years+ - NCT06694012Recruiting
Ohtori Study Part 2 heart health
This study looks at heart and metabolic health in the general population. It helps researchers understand how to prevent conditions like diabetes and heart disease.
Sakai, OsakaAges 20 years+ - NCT07515794Enrolling by invitation
Long-term follow-up for transplant access study participants
This is a follow-up study for people who already participated in the STEPS research project about improving fairness in organ transplants. Researchers want to track how participants are doing over time and learn more about transplant outcomes.
Winston-Salem, North CarolinaAges 18–75 - NCT06727409RecruitingPhase 4
Triple therapy for type 2 diabetes and kidney disease
This study tests whether adding a non-steroidal mineralocorticoid antagonist to your current type 2 diabetes and kidney disease medications (SGLT2i and ACEi/ARB) is cost-effective. It may help preserve kidney function and reduce heart risks.
Hong KongAges 18 years+ - NCT06860711RecruitingPhase 4
NSAID safety in children with kidney disease having surgery
This study tests if a short course of NSAID pain relievers is safe for children with mild to moderate kidney disease who are having urologic surgery requiring an overnight hospital stay. The goal is to find better ways to manage pain after surgery in these patients.
Aurora, ColoradoAges 1.5 years–25 years - NCT06886282Recruiting
How colon cancer and kidney disease are linked: a imaging and gene study
This trial uses advanced imaging and genetic tests to understand how colon cancer and chronic kidney disease may be connected. It may help decide the best treatment for people with both conditions.
NaplesAges 18 years+ - NCT06906627Recruiting
Improving kidney screening for people with diabetes
This study helps people with type 2 diabetes get the right kidney tests to catch kidney problems early. Your doctor will check your kidney health through a simple blood and urine test.
Birmingham, AlabamaAges 18 years+ - NCT06906640Recruiting
Improving Kidney Care for People with Type 2 Diabetes
This study tests a program to help primary care doctors better screen and manage kidney problems in people with type 2 diabetes. It aims to see if using recommended medicines can slow kidney disease and improve health.
Birmingham, AlabamaAges 18 years+ - NCT06913647RecruitingPhase 2
Canagliflozin for fluid removal and health in peritoneal dialysis patients
This trial tests if canagliflozin, a diabetes medicine, helps remove extra fluid and reduce scarring in people on peritoneal dialysis (home-based dialysis). It may improve your dialysis results and protect your belly lining.
Montreal, QuebecAges 18 years+ - NCT06929169RecruitingPhase 2
SGLT2 inhibitor heart health study in dialysis patients
This study tests whether a medicine called an SGLT2 inhibitor (a type of diabetes drug also used for heart failure) affects the heart and blood vessels in people with kidney failure who are on dialysis. It will help doctors understand if this medicine is safe and helpful for dialysis patients.
Buenos Aires, Buenos AiresAges 18–70 - NCT06932042Recruiting
Protein-controlled diet for kidney disease management
This trial tests a low-protein diet (called PLADO) to help manage chronic kidney disease (CKD) stages 3–5. It aims to slow kidney decline and improve nutrition. You may join if your kidney function is stable and your blood sugar and blood pressure are under control.
BeirutAges 18 years+ - NCT06933108Recruiting
Predicting Nerve Damage with Simple Function Tests
This study looks at whether simple function tests can predict nerve damage in people with advanced kidney disease or diabetes. It aims to find early signs of nerve problems before they become serious.
Le MansAges 60–80 - NCT06978127Recruiting
Tech help for dialysis patients to feel better
This study tests a program that uses technology to help people on dialysis feel better and take a more active role in their care. It may help you if you are on dialysis and want extra support.
Albuquerque, New MexicoAges 18 years+ - NCT06986265Recruiting
Kidney failure, weight loss, and gut health study
This study looks at how gut bacteria might affect weight loss in people with kidney failure who are on dialysis. It may help find new ways to prevent or treat weight loss in this condition.
BrusselsAges 18 years+ - NCT06997042Recruiting
Comparing Two Fistula Creation Techniques for Dialysis
This study compares two surgical techniques for creating an arteriovenous fistula (AV fistula), a special connection between an artery and a vein in the arm that makes dialysis easier. If you need dialysis for advanced kidney disease, this trial aims to see which method works better and lasts longer.
Barcelona, BarcelonaAges 18 years+ - NCT07021157RecruitingPhase 1
First-in-human study of SK-08 in healthy volunteers
This trial tests a new drug called SK-08 in healthy volunteers to see if it's safe and how the body processes it. It helps doctors find the right dose for future studies of this potential medicine.
Hangzhou, ZhejiangAges 18–45 - NCT07025629RecruitingPhase 3
Dapagliflozin after ICU discharge for heart and kidney health
This study tests if the drug dapagliflozin (a medicine that helps protect the heart and kidneys) can improve recovery in patients who needed a breathing machine or blood pressure support in the ICU. If you qualify, you would take the drug after leaving the ICU to see if it lowers the risk of heart or kidney problems.
ParisAges 18 years+ - NCT07029503RecruitingPhase 2
Heart failure and kidney function study
This trial tests a new treatment for people with heart failure and severely reduced kidney function. It aims to see if the treatment can help protect both the heart and kidneys.
StockholmAges 18 years+
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Common questions
- Are there clinical trials for chronic kidney disease?
- Yes. Clin2 currently lists 571 recruiting chronic kidney disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic kidney disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic kidney disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.