Clinical trials
Chronic kidney disease clinical trials
A gradual loss of kidney function over time. We’re tracking 561 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07745920Recruiting
An online program for depression in people with adpkd
This study tests an internet-based program to help manage depression symptoms in people with ADPKD. The program may be a convenient way to get support for your mood without traveling to a clinic.
Rochester, MinnesotaAges 18–70 - NCT07734610RecruitingPhase 1
Testing Nemtabrutinib in People with Severe Kidney Disease
This trial tests a new medicine (nemtabrutinib) in people with severe kidney disease to see how the body handles it. The study helps doctors decide safe doses for people with kidney problems.
Miami Lakes, FloridaAges 18–80 - NCT07600450RecruitingPhase 1
First study of a new drug in healthy adults
This study tests a new investigational drug to see how safe it is and how the body processes it. It is one of the first steps in drug development, and it helps determine if the drug is suitable for further testing.
GroningenAges 25–55 - NCT07571746RecruitingPhase 2
Surovatamig for antibody-mediated kidney disease
This study tests a new medicine called surovatamig for adults with a specific type of kidney disease caused by the body's own antibodies (anti-PLA2R antibody-positive membranous nephropathy). The medicine may help reduce kidney damage and improve kidney function.
Los Angeles, CaliforniaAges 18–75 - NCT06760845Recruiting
Using light to diagnose kidney disease
This trial uses a special light technique (Raman spectroscopy) to help diagnose different types of kidney disease. It may provide a faster, less invasive way to understand your condition.
Jinan, ShandongAges Any age - NCT07442448Enrolling by invitationPhase 4
Study of Finerenone for heart and kidney health in diabetes
This trial tests a medication called Finerenone to see if it can improve heart structure and function in people with both diabetic kidney disease and heart failure. If you have type 2 diabetes, kidney problems, and heart failure with preserved pumping function, this study may explore a new treatment option for you.
TaipeiAges 18 years+ - NCT07271420RecruitingPhase 4
Blood pressure drug study for dialysis patients
This trial tests whether a common blood pressure medication (thiazide diuretics) helps control high blood pressure in people on peritoneal dialysis. The goal is to see if it can lower blood pressure and improve health.
Hong KongAges 18 years+ - NCT07224763RecruitingPhase 1/Phase 2
Pig kidney transplant trial for kidney failure patients
This trial tests a genetically modified pig kidney (Thymokidney) for people with end-stage kidney disease who are on dialysis. It aims to see if this new type of transplant is safe and effective for those who cannot get a human kidney.
New York, New YorkAges 40–70 - NCT07216391RecruitingPhase 2
Trial to delay type 1 diabetes: teplizumab vs. ATG
This study compares two medicines (teplizumab and anti-thymocyte globulin) to see if they can delay the onset of type 1 diabetes in people who are at high risk but don't have symptoms yet. If you have certain diabetes-related antibodies in your blood, this trial might help keep full-blown diabetes away for longer.
Aurora, ColoradoAges 4–34 - NCT07191561Recruiting
Liver fat and alcohol use disorder study
This trial looks at how the liver processes fat in people with alcohol use disorder. It may help find better ways to treat liver problems related to drinking.
Bethesda, MarylandAges 18–100 - NCT07175051RecruitingPhase 2
Testing a kidney-protecting drug in sickle cell disease
This study tests whether empagliflozin, a medicine that protects the kidneys in people with diabetes, can also protect the kidneys in people with sickle cell disease. The goal is to see if it can reduce protein in the urine, which is a sign of kidney stress.
Chicago, IllinoisAges 18–60 - NCT07167368Recruiting
Exercise rehab for heart and kidney health
This trial tests whether a supervised exercise program can help people with heart failure and mild-to-moderate kidney problems. It might improve both your heart and kidney function.
Nantong, JiangsuAges 18–75 - NCT07142252RecruitingPhase 2
New drug for recently diagnosed type 1 diabetes
This trial tests a new medicine (rezpegaldesleukin) to see if it can help preserve the body's ability to make some insulin in people recently diagnosed with type 1 diabetes. It's for children and adults diagnosed within the past 100 days.
San Francisco, CaliforniaAges 8–45 - NCT07122921Recruiting
Sleep study in Hong Kong children with cancer
This study compares sleep patterns in children with cancer, children with other chronic illnesses, and healthy children. Researchers want to understand how cancer and its treatment affect sleep during hospitalization.
Hong KongAges 6–18 - NCT05349955Recruiting
Primary care diabetes guideline program for older adults
This trial tests whether a diabetes treatment plan (based on published guidelines) delivered by primary care doctors in the community is safe and helpful for older adults. It focuses on people with type 2 diabetes who also have kidney problems and/or higher heart and blood-vessel risk.
Suzhou, JaingsuAges 65 years+ - NCT06958016Recruiting
Tryptase levels in stable coronary artery disease
This study looks at levels of tryptase, a protein in your blood, in people with stable coronary artery disease. It aims to see if these levels are linked to heart health, which could help doctors better understand and manage your condition.
Athens, AtticaAges 18–85 - NCT06878560RecruitingPhase 1/Phase 2
Pig kidney transplant for kidney failure patients
This trial tests a special pig kidney (10 GE Xenokidney) as a transplant option for people with kidney failure who cannot get a human kidney. It aims to offer a life-saving alternative.
Chicago, IllinoisAges 40–70 - NCT06820970Recruiting
Combined therapy for heart artery blockages that weren't fully opened
This trial tests if combining a new heart procedure with a special type of therapy called mindfulness therapy can help prevent heart problems in people with coronary artery disease that could not be fully fixed with stents or surgery.
Zhengzhou, HenanAges 18 years+ - NCT06714006RecruitingPhase 1
Testing safety of PYC-003 for ADPKD
This study is testing a new investigational medicine called PYC-003 for people with autosomal dominant polycystic kidney disease (ADPKD). It is one of the first studies in humans, so the main goal is to see if the medicine is safe and tolerable. The study is for people with a specific genetic cause (PKD1 mutation) and with certain kidney imaging types.
Southport, Gold CoastAges 18–65 - NCT06666283RecruitingPhase 1
Testing a new drug for diabetic kidney disease
This study tests a new medicine called AP303 for people with type 2 diabetes and chronic kidney disease. The goal is to see if it is safe and how the body processes it. If you have diabetes and your kidneys are not working as well as they used to, this trial might help find new treatment options.
Beijing, Beijing MunicipalityAges 30 years+ - NCT06635629RecruitingPhase 2
Desmopressin test for ACTH-dependent Cushing syndrome
This trial studies how well a desmopressin stimulation test works to diagnose ACTH-dependent Cushing syndrome. It compares results from people with possible or recurrent Cushing syndrome and healthy volunteers.
Bethesda, MarylandAges 18–70 - NCT06291077RecruitingPhase 4
Belatacept vs anticalcineurins after kidney transplant
This study is comparing two medications after kidney transplant: Belatacept and anticalcineurins (like tacrolimus). It looks at how each affects blood vessel health. If you are more than a year post-transplant and have stable kidney function, you may be eligible.
RouenAges 18–75 - NCT05159466Recruiting
Transplant from HIV-positive donors to HIV-positive recipients
This trial studies whether it’s safe and effective for HIV-positive people to receive organ transplants from HIV-positive donors. It focuses on matching HIV treatment before and after transplant and checking for major complications.
Metairie, LouisianaAges 18 years+ - NCT06071429Recruiting
Dissolvable medicine stent for leg artery disease
This trial tests a new dissolvable stent that slowly releases medicine to keep your lower-leg artery open. It is for people with severe leg pain or small wounds due to poor blood flow, and who are not eligible for other stents.
New York, New YorkAges 18 years+
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Common questions
- Are there clinical trials for chronic kidney disease?
- Yes. Clin2 currently lists 561 recruiting chronic kidney disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic kidney disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic kidney disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.