Clinical trials
Chronic Pain Management clinical trials
Below are recruiting chronic pain management clinical trials, each written for real people, not researchers. We’re tracking 221 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07096661Enrolling by invitation
Pain education for labor and postpartum pain
This study tests a way of teaching about pain (called pain science education) to help healthcare professionals better support women during labor and after birth. If you are a healthcare professional who works with pregnant or new mothers, this trial may be for you.
BournemouthAges Any age - NCT06029075Recruiting
Brain stimulation for nerve pain after spinal injury
This study tests whether a gentle electrical current applied to the scalp can help relieve nerve pain that continues after an injury to the spinal cord, arm or leg amputation, or brain injury. Participants will continue their usual pain medications during the trial.
Houston, TexasAges 18–75 - NCT06246929Recruiting
Healthy aging for Black adults with chronic pain and memory concerns
This study tests a program to help Black adults aged 50+ manage chronic pain and early memory changes. It compares two approaches to see which works better for improving daily life and thinking skills.
Boston, MassachusettsAges 50 years+ - NCT06602349Recruiting
Lidocaine injection for chronic anal/perineal pain
This trial tests whether injecting a numbing medicine (lidocaine) into the painful area helps people with chronic, unexplained pain in the anal or perineal region. It is for patients who have not gotten relief from standard treatments and whose MRI shows no other cause.
Paris, Île-de-France RegionAges 18 years+ - NCT07141108Recruiting
Using a digital tool to track chronic pain and improve quality of life
This trial tests a digital tool that helps you track your pain and activity level. The goal is to see if using the tool can improve your quality of life. You would use a smartphone or tablet app and share updates with your primary care team.
Malmö, Skåne CountyAges 18 years+ - NCT07094282Recruiting
Integrative therapies study for chronic back or neck pain
This study is testing integrative medicine therapies for chronic back or neck pain. It is for military members and their families who receive care at Nellis Air Force Base. The goal is to see if these therapies can help reduce pain and improve quality of life.
Nellis Air Force Base, NevadaAges 18 years+ - NCT07002944Recruiting
Testing nerve treatment for shoulder pain after mastectomy
This study compares two types of pulsed radiofrequency (a minimally invasive treatment using radio waves) to see which better relieves shoulder pain in women who have had a mastectomy. It's for women who still have pain despite taking a high dose of tramadol.
CairoAges 18–65 - NCT04811209Recruiting
Testing better pain control and recovery after orthopedic surgery
This trial looks at how well a pain-control plan works after certain orthopedic surgeries and how it affects recovery and patient-reported outcomes. It may help determine what level of pain relief is meaningful to patients after surgery.
Toronto, OntarioAges 18–80 - NCT06382272Recruiting
Bionic breast project to reduce chronic pain after mastectomy
This study tests a new device (a neuroprosthesis) placed during breast reconstruction to see if it can reduce long-term pain after a mastectomy. If you are having both breasts removed and plan to get tissue expander reconstruction, you may be able to join.
Chicago, IllinoisAges 18 years+ - NCT07410000Recruiting
Block for pain after hip replacement
This trial tests a nerve block to reduce pain after hip replacement surgery. It may help you need fewer painkillers and recover more comfortably.
BursaAges 18–80 - NCT06946290Recruiting
Nerve block for pain relief after heart surgery
This study tests a nerve block, called an intertransverse process block, to see if it helps people feel better and recover faster after heart surgery. The block is given during surgery to reduce pain.
Hong KongAges 18 years+ - NCT07652944Recruiting
Magnetic field therapy for chronic lower back pain
This trial tests whether magnetic fields applied to your back can relieve chronic lower back pain that has lasted at least 12 weeks. It's for people aged 18 to 64 who are willing to attend all study visits.
Edwards Air Force Base, CaliforniaAges 18–64 - NCT06509087Recruiting
Combining CT and MRI for joint pain procedure
This study tests a procedure called transarterial microembolization for chronic shoulder or knee pain that hasn't improved with other treatments. It uses both CT and MRI to guide the procedure and see if it can help reduce pain.
TaipeiAges 20–80 - NCT06327542Recruiting
Group pain management in primary care clinics
This trial tests a group-based program to help people with chronic pain manage their symptoms. It is offered in primary care clinics that serve underinsured communities, and sessions are available in English or Spanish.
San Francisco, CaliforniaAges 18 years+ - NCT07123805Recruiting
Acupuncture for knee replacement recovery
This study tests if adding acupuncture before and after knee replacement surgery helps reduce pain and improve recovery. It may be an option for people having planned knee replacement for osteoarthritis.
Pavia, PaviaAges 18 years+ - NCT04658628Recruiting
Brain scan study to learn who responds to spinal cord stimulation
This trial uses brain imaging to understand which people with long-lasting low back pain are more likely to benefit from spinal cord stimulation (SCS). If you’re being considered for an SCS trial, the scans may help researchers predict response and improve future care.
Los Angeles, CaliforniaAges 21 years+ - NCT07000409Recruiting
Ultrasound-guided nerve block for shingles pain
This trial tests if a nerve block with betamethasone can reduce long-term shingles pain on the trunk. It may help people who still have pain more than 3 months after the rash appeared.
CairoAges 18–75 - NCT04730700Recruiting
Radiofrequency treatment test for facet back pain
This study compares a nerve procedure (radiofrequency “neurotomy” using an expandable electrode) to non-procedure medical care for long-lasting low back pain from facet joints. It aims to see whether the procedure helps more safely than conservative treatment.
Kansas City, KansasAges 18 years+ - NCT07328256Recruiting
Comparing two muscle relaxation techniques for neck pain relief
This study looks at two different gentle stretching methods to see which works better for relieving neck pain. It might help if you have had neck pain for a while and it limits your movement.
Islamabad, Punjab ProvinceAges 19–44 - NCT05961800Recruiting
Study ways to evaluate lumbar back pain blocks
This study looks at how well different methods can evaluate a common procedure used for chronic low back pain (lumbar medial branch blocks). If you have long-lasting, everyday back pain and are having this procedure, you may help researchers compare evaluation approaches.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT05968664Recruiting
Test whether new spinal cord stimulation settings improve chronic pain
This trial studies whether changing the “stimulation pattern” of spinal cord stimulation can reduce long-lasting pain and improve daily function. You might be a good candidate if you have chronic trunk or leg pain and have already tried multiple pain treatments without enough relief.
Houston, TexasAges 22 years+ - NCT07309731Recruiting
Hot vs. cold radiofrequency for chronic low back pain from facet joints
This trial compares two types of radiofrequency treatment (cooled vs. thermal) to see which works better for chronic pain coming from the small joints in your lower back. It is for people who have had back pain for at least 3 months and haven't gotten enough relief from usual treatments like pain medicine or physical therapy.
Zagazig, ElsharqyaAges 30–70 - NCT06518720RecruitingPhase 2
Psilocybin for Chronic Nerve Pain and Depression
This trial tests whether psilocybin (a psychedelic medication) can help people who have both chronic nerve pain and depression that hasn't responded to standard treatments. The goal is to see if it can reduce pain and improve mood.
Toronto, OntarioAges 18–65 - NCT04787848Recruiting
Testing pain causes and treatments in people with HIV
This study looks at why chronic widespread pain happens in people with HIV and tests new ways to understand and treat it. You may be able to join if your HIV is stable on treatment and you meet pain and safety requirements.
Miami, FloridaAges 19–65
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Common questions
- Are there clinical trials for chronic pain management?
- Yes. Clin2 currently lists 221 recruiting chronic pain management studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic pain management trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic pain management trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.