Clinical trials
Chronic pain clinical trials
Pain that lasts for months or longer, often after the original cause has healed. We’re tracking 793 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07630142Recruiting
Massage methods for chronic neck pain: an imaging study
This trial compares two types of massage—long, gentle strokes versus a handheld massager—for relieving long-lasting neck pain. Ultrasound imaging will be used to see how the muscles respond.
PoznanAges 18–60 - NCT06840314Recruiting
Vibration vs traditional therapy for painful sex
This trial compares a vibrating vaginal device to standard therapy for women with pain during sex. It aims to find a more effective and comfortable treatment option.
Washington D.C., District of ColumbiaAges 18 years+ - NCT07662733Recruiting
Acupuncture for better sleep and less pain after lung cancer surgery
This trial tests if acupuncture given before and after surgery can help patients sleep better and have less chronic pain after a lung cancer operation. You may join if you are having a specific type of lung cancer surgery, are in good general health, and do not have severe sleep problems already.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT05172739RecruitingPhase 4
Opioid-free anesthesia during lung surgery for early lung cancer
This study tests whether an opioid-free pain/anesthesia plan during elective lung surgery can reduce surgical “stress” on the body and affect the immune system. You may be eligible if you have early-stage non-small cell lung cancer and are scheduled for a specific type of surgery (VATS lobectomy).
Heraklion, CreteAges 18–80 - NCT06270121Recruiting
Mobile health app for healthy aging at home
This study is testing a mobile health app designed to help seniors live independently at home. If you join, you will use the app and answer surveys to see if it supports healthy aging.
SeoulAges 65 years+ - NCT05812885Recruiting
TENS for long-lasting low back pain
This study tests whether transcutaneous electrical nerve stimulation (TENS), a non-drug pain treatment using small electrode pads on the skin, can help people with low back pain. You may be eligible if your back pain has lasted at least 3 months and your pain is at least moderate.
West Hartford, ConnecticutAges 18–60 - NCT07556952RecruitingPhase 4
Dexamethasone to reduce pain after breast removal surgery
This study tests whether dexamethasone (a common anti-inflammatory medication) can reduce pain after mastectomy (surgical removal of breast tissue). Researchers want to see if it helps patients recover with less pain and potentially fewer pain medications.
Montreal, QuebecAges 18–75 - NCT07127380Recruiting
Comparing two types of spine surgery for disc-related low back pain
This study compares two different surgery methods (Mini-TLIF and MIDLIF) for treating low back pain caused by worn-out discs in the lower back. The goal is to see which one offers better recovery, fewer complications, and lower costs.
Lodz, Łódź VoivodeshipAges 18 years+ - NCT06932887RecruitingPhase 3
Walking to reduce arthritis pain
This study tests a walking program to help reduce pain from osteoarthritis. It is designed for people with arthritis in their hips, knees, feet, or spine.
Salt Lake City, UtahAges 45 years+ - NCT06921694Recruiting
Exercise program for lower back pain
This trial tests a combined exercise program with stretching, strength, and aerobic exercises to help relieve chronic lower back pain. It looks at whether specific movements can reduce pain and improve daily function.
Nottingham, NottsAges 18–45 - NCT06533345Recruiting
Pain-free research for chronic pain
This trial studies a collaborative approach to help people with chronic pain, which is pain that lasts beyond a recent injury. It may be a good fit if you're not currently seeking medication for your pain.
Auburn, AlabamaAges 21–80 - NCT06222151Recruiting
Recovering from weight-loss surgery with early walking
This study tests whether starting a supervised walking program soon after weight-loss surgery helps you recover faster. It aims to see if early movement improves your recovery and hospital stay.
Esbjerg, Region SyddanmarkAges 18–70 - NCT05741788Recruiting
Telefitting spinal cord stimulation for chronic pain
This study checks a “remote fitting” process to set up spinal cord stimulation for people with high levels of pain. You may be a fit if you are planning a stimulation trial and have severe pain right now.
Minneapolis, MinnesotaAges 22 years+ - NCT04556890Recruiting
Brain stimulation for treatment-resistant depression and chronic pain
This study tests a non-invasive brain stimulation treatment, called transcranial magnetic stimulation (TMS), to see if it can help people who have both major depression that hasn't improved with medication and chronic pain from fibromyalgia or chronic fatigue syndrome. It aims to reduce both depression and pain symptoms.
Los Angeles, CaliforniaAges 18–75 - NCT07555496Recruiting
Back Pain Treatment After Spine Surgery: Injection vs. Needling
This study compares two ways to treat long-lasting back pain in people who have had spine surgery: injections into the back muscles versus dry needling (inserting thin needles into tight muscles). Both are combined with physical therapy to see which helps reduce pain better.
St-MaloAges 18 years+ - NCT07211464Recruiting
ACT plus exercise for older adults with chronic low back pain
This study tests whether combining acceptance and commitment therapy (ACT) with exercise helps older adults manage ongoing low back pain. If you've had pain for at least 3 months and it's been bothering you, this approach might teach you new ways to cope and move better.
Hong KongAges 60 years+ - NCT07284407Recruiting
Learning about pain and touch training for long-term back pain
This study tests two types of therapy for ongoing low back pain: learning about how pain works (pain education) and training your sense of touch (sensory discrimination). The goal is to help your brain process pain better and reduce discomfort.
LahoreAges 19–44 - NCT07109843Recruiting
Boswellia for pain and sensitivity in healthy volunteers
This trial tests whether a supplement called Boswellia serrata (frankincense) can change how your body processes pain and touch. It is for healthy people who do not have chronic pain or use certain medications.
Graz, StyriaAges 18 years+ - NCT06344169RecruitingPhase 2/Phase 3
Pain relief after C-section with Naldebain
This trial tests a long-acting painkiller, Naldebain, for women having a planned C-section. It aims to see if it provides better pain control after the surgery.
Dalin, Chai-YiAges 20 years+ - NCT06724679Recruiting
Virtual reality for chronic back pain treatment
This trial tests if using a virtual reality (VR) headset can help people with long-term lower back pain during a spine rehabilitation program. It will see if VR is a practical and helpful addition to the program.
AngersAges 18–65 - NCT07836439Enrolling by invitation
Comparing two manual therapies for low back pain relief
This study compares two hands-on treatments, the Graston Technique and diacutaneous fibrolysis, to see which works better for reducing low back pain, improving function, and enhancing quality of life. If you have non-specific low back pain (pain without a clear cause), this trial may help you find a new way to manage your symptoms.
Sialkot, Punjab ProvinceAges 20–40 - NCT04853732Recruiting
Pain research registry for chronic low back pain
This study is a research registry that collects information from people with chronic low back pain (and some people without chronic pain). It may help researchers better understand pain patterns and guide future treatments.
Fort Worth, TexasAges 21–79 - NCT07731750Recruiting
Smart pain treatment plan for chronic low back pain
This study tests a computer-based tool to help choose the best pain treatments for people with chronic low back pain. It compares different treatments to see which ones work best for each person.
Ann Arbor, MichiganAges 25 years+ - NCT07729722Enrolling by invitation
Chiropractic vs physiotherapy for chronic neck pain
This study compares two different treatments for people with long-term neck pain: chiropractic care and physical therapy. The goal is to see which approach works better to reduce pain and improve function.
IstanbulAges 18–65
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Common questions
- Are there clinical trials for chronic pain?
- Yes. Clin2 currently lists 793 recruiting chronic pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.