Clinical trials
Chronic pain clinical trials
Pain that lasts for months or longer, often after the original cause has healed. We’re tracking 793 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05817786Recruiting
Electrical nerve stimulation for persistent arm nerve pain
This trial tests whether stimulating the nerve roots in the shoulder area can reduce long-lasting nerve pain in one arm. It may help people whose arm pain has not improved with standard nerve-pain treatments.
Lyon, FranceAges 1.5 years–80 years - NCT07282392Recruiting
Emotional awareness therapy for lupus and fibromyalgia pain
This study tests if a therapy called Emotional Awareness and Expression Therapy (EAET) can help people with lupus and fibromyalgia or chronic widespread pain feel better by addressing emotional factors that may worsen their pain. You would attend sessions to learn how to understand and express your emotions in healthy ways.
Salt Lake City, UtahAges 18–65 - NCT07217821Recruiting
Music and imagery for chronic pain
This study tests a step-by-step approach using music and guided imagery to help people with long-term muscle or joint pain. It's done from home using a device, so you don't need to travel.
Indianapolis, IndianaAges 18 years+ - NCT07035314Recruiting
Comparing medicines for pain after tonsil removal in children
This study compares two ways to manage pain after tonsil removal in children: a medication given by mouth or injection versus a medication applied directly to the surgical site. The goal is to find which approach works better for pain control.
CairoAges 4–10 - NCT06977100Recruiting
Journaling study for jaw pain with other chronic pain conditions
This study tests if a journaling program can help people with jaw pain and at least one other chronic pain condition (like fibromyalgia, IBS, or migraines). You will write about your thoughts and feelings to see if it reduces pain and improves well-being.
Gainesville, FloridaAges 18–80 - NCT06962475Recruiting
Custom foot orthotics for chronic forefoot pain
This trial tests if custom foot orthotics (shoe inserts) can reduce chronic pain under the ball of the foot. If you have had forefoot pain for at least 3 months and can walk without a cane or walker, you may be able to join.
Trois-Rivières, QuebecAges 18 years+ - NCT06936800Enrolling by invitation
Pinaverium Bromide to Prevent Pain After Shock Wave Treatment
This trial tests if a drug called pinaverium bromide can help prevent pancreatitis and reduce pain after a procedure that uses shock waves to break up large gallstones in the pancreas. It may be an option for people with chronic pancreatitis and stones that are at least 5 mm wide.
Jinan, Wenhuaxi RoadAges 18–85 - NCT06885931Recruiting
Nerve stimulation trial for mixed urinary incontinence
This trial tests a new implant that stimulates a nerve in your pelvic area to help control both stress and urge urine leaks. It might be an option if you've tried other treatments like bladder training or medicine and they didn't help enough or caused side effects.
Leuven, Herestraat 49Ages 22 years+ - NCT06796985RecruitingPhase 1
Botox for Chronic Pelvic Pain in Women
This study tests whether a Botox injection into the pelvic floor muscles can reduce chronic pelvic pain. It is for women who have had pelvic pain for at least 6 months, with tender muscle knots in the pelvic area.
Miami, FloridaAges 18–75 - NCT06641102Recruiting
Healing track for chronic back pain
This trial tests a non-drug, talk-based therapy approach for chronic back pain. It may help you manage pain without medication, and all study activities can be done from home using your smartphone.
New York, New YorkAges 21–70 - NCT06087510RecruitingPhase 4
Different doses of esketamine and dexmedetomidine for pain after scoliosis surgery
This trial tests two different doses of esketamine and dexmedetomidine to see which provides better pain relief after scoliosis correction surgery. It aims to improve your recovery and long-term outcomes.
Beijing, Beijing MunicipalityAges 18 years+ - NCT04177511Recruiting
Vagus nerve ear stimulation for endometriosis pelvic pain
This trial tests whether stimulating a nerve through the ear (non-surgical, through the skin) can reduce chronic pelvic pain from endometriosis. It may help if standard care hasn’t fully controlled symptoms like painful periods or pain during sex.
Suresnes, Île-de-France RegionAges 15 years+ - NCT05245695Recruiting
Endometriosis test using deep computer learning during surgery
This trial studies whether a computer (deep neural network) can better identify endometriosis in people with long-lasting pelvic pain using information from surgery. It may help doctors sort who has endometriosis more accurately when surgery is already planned.
Chandler, ArizonaAges 14–50 - NCT07327554Recruiting
Lumbar movement fluidity study for chronic low back pain
This trial uses wearable sensors to measure how smoothly your lower back moves before and after rehabilitation. It aims to see if rehabilitation improves movement fluidity in people with chronic low back pain.
MontpellierAges 18–65 - NCT07317518Recruiting
Taping for chronic low back pain
This trial tests two different kinesio taping methods for people with chronic low back pain. The goal is to see how taping affects the fascia (connective tissue) in the lower back and whether it can help relieve pain.
Center, Kirşehi̇rAges 18–65 - NCT07846163Recruiting
Pain assessment for chronic low back pain
This study looks at how the brain and nervous system process pain in people with long-lasting low back pain. It uses safe measurements inside a shielded room to compare chronic pain patients with healthy people, which may help improve pain treatments.
Thessaloniki, Central MacedoniaAges 18–45 - NCT05511012Recruiting
Testing movement-control assessment in low back pain
This study checks whether a therapist’s judgment about how your back controls movement matches objective measurements (more technical testing). It may help improve how low back pain rehabilitation is assessed and planned.
Brest, FinistèreAges 18–99 - NCT04824248Recruiting
Weight-loss program for chronic low back pain
This trial studies whether weight loss can improve long-lasting, non-specific low back pain. It may help people whose back pain is partly related to extra weight by testing a structured approach over time.
BrusselsAges 18–65 - NCT07338045Recruiting
Baduanjin exercise for chronic low back pain in office workers
This trial tests whether an eight-week Baduanjin exercise program can reduce chronic low back pain and improve daily function in office workers. Baduanjin is a gentle mind-body practice that involves slow movements and breathing, and it may help relieve pain caused by prolonged sitting.
Xi'an, ShaanxiAges 20–55 - NCT07216417Recruiting
Virtual yoga for chronic low back pain
This study tests whether a virtual yoga program can help reduce chronic low back pain. You'll attend online yoga classes from home, and the study will also ask about your experience.
Kansas City, KansasAges 30–80 - NCT07403331Recruiting
Nerve pain in legs: spinal cord stimulation plus team care
This trial tests a treatment bundle that combines a spinal cord stimulator (a device that sends mild electrical pulses to your spine to block pain signals) with a team of specialists (like a psychologist and physical therapist) to reduce chronic nerve pain in the legs and improve your ability to move and function.
OsloAges 18–60 - NCT06715761Recruiting
Myofascial release for chronic low back pain in CrossFit athletes
This trial tests if a hands-on or tool-assisted muscle release technique can reduce long-term low back pain and improve posture in people who do CrossFit. If you have had low back pain for at least 12 weeks and do CrossFit regularly, this study may help you find relief.
Goiânia, GoiásAges 18–59 - NCT04273828Recruiting
Study of muscle changes in chronic low back pain surgery
This study looks at how muscle degeneration relates to nerve-related symptoms in people with chronic low back pain. You may be eligible if you’ve tried non-surgical care but still need surgery to relieve nerve pressure.
São Paulo, São PauloAges 18 years+ - NCT07878273Recruiting
Tibial nerve size in chronic plantar fasciitis
This study compares the size of a nerve in the foot (the tibial nerve) between people with chronic plantar fasciitis and healthy individuals. It aims to understand if nerve changes are linked to this condition, which might help improve future treatments.
IstanbulAges 18–65
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Common questions
- Are there clinical trials for chronic pain?
- Yes. Clin2 currently lists 793 recruiting chronic pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.