Clinical trials
Chronic pain clinical trials
Pain that lasts for months or longer, often after the original cause has healed. We’re tracking 828 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07742228Recruiting
SCENAR therapy for long-term neck pain
This study tests a device called SCENAR that uses gentle electrical signals to help reduce chronic neck pain. It may be an option for people whose neck pain has lasted at least 3 months and who have not found relief with other treatments.
Suresnes, Île-de-France RegionAges 18–80 - NCT04880096Recruiting
Study of people living with chronic pain
This study follows people with long-term (chronic) pain to better understand their experience. It may help researchers evaluate what support or care could be more helpful for chronic pain patients.
Clermont-Ferrand, AURAAges 18 years+ - NCT05069363Recruiting
Light therapy for widespread chronic pain
This trial tests whether using a whole-body light treatment (photobiomodulation) can reduce widespread chronic pain. It may help if you have long-lasting, widespread pain and can safely use the device for about 6 weeks.
BirminghamAges 18–100 - NCT05407610Recruiting
Compare two types of nerve pain treatments for knee pain
This study compares conventional versus cooled radiofrequency treatments for long-lasting knee pain. It aims to see which method reduces pain better and helps patients function more comfortably.
AntwerpAges 18 years+ - NCT05540548Recruiting
Podiatry assessment for balance and pain in chronic back pain
This study looks at whether a foot and posture specialist can help measure how balance relates to the pain you feel in chronic low back pain. It may help doctors better understand what to focus on for pain that lasts for months.
ValenciennesAges 18 years+ - NCT05700279Recruiting
PTSD treatment to help prevent future chronic pain
This study tests whether treating post-traumatic stress disorder (PTSD) right when you come to the emergency room for new, acute pain can lower the chance you develop long-term (chronic) pain. It may help people whose pain and trauma symptoms start around the same time.
Chicago, IllinoisAges 18–70 - NCT05701852Recruiting
Study brain scans during tasks in chronic nerve pain
This study looks at how brain activity changes in people with long-lasting nerve pain using an MRI scan while you do simple behavioral tasks. It may help researchers understand brain function in chronic neuropathic pain and how it affects day-to-day abilities.
ParisAges 18 years+ - NCT05986292RecruitingPhase 2
Study of new treatments for chronic pain
This study tests new treatments for chronic pain that lasts at least 3 months. Participants must stop their regular pain medicines and use only a rescue painkiller if needed. The goal is to find better ways to manage long-term pain.
Birmingham, AlabamaAges 18 years+ - NCT06004804Recruiting
Video group therapy for chronic pain in older Veterans
This study tests whether group therapy sessions held over video can help older Veterans manage chronic muscle or joint pain. It focuses on teaching practical skills to reduce pain and improve quality of life.
West Los Angeles, CaliforniaAges 60–95 - NCT06153303Recruiting
Online therapy for endometriosis and chronic pain
This trial tests if an internet-based program based on acceptance and commitment therapy (ACT) can help people with endometriosis and chronic pain. It aims to improve daily functioning and quality of life.
Lund, Skåne CountyAges 18–65 - NCT06336447Recruiting
Virtual reality and nerve block for chronic knee pain
This study tests whether using virtual reality (VR) before a standard heat-based nerve block (radiofrequency ablation) can improve relief of long-term knee pain caused by arthritis. If you qualify, you'll receive the RFA procedure and may be randomly assigned to also use VR.
Chicago, IllinoisAges 18 years+ - NCT06436378Recruiting
Music Therapy for Chronic Pain Patients
This study tests whether listening to music can help people with chronic pain feel better. It is for people who are already being treated at the pain clinic at CHU de Québec-Université Laval and can attend a few sessions at the university.
Québec, QuebecAges 18 years+ - NCT07682519Recruiting
Home vs. in-person rehab for hemophilia pain
This study compares a rehabilitation program you can do at home using video calls (telerehabilitation) with in-person rehabilitation sessions. The goal is to see if the home-based option works as well as office visits for reducing chronic joint pain in adults with hemophilia.
Santiago, Santiago MetropolitanAges 18–60 - NCT06795243Recruiting
Physical therapy for endometriosis and exercise adherence
This study tests whether physical therapy (exercise for your muscles) can help with endometriosis symptoms and how well people stick with the program. If you have endometriosis and can do light strength exercises, you may be able to join.
SevilleAges 18 years+ - NCT06811077Recruiting
Health coaching by a patient expert for chronic pain
This trial tests whether one-on-one coaching sessions led by a trained patient expert can help people better manage chronic pain. If you already attend a chronic pain clinic and are open to learning new coping skills, this program may support you.
Paris, FranceAges 18 years+ - NCT06816082Recruiting
Online therapy for chronic pain rehabilitation
This trial tests if adding internet-based acceptance therapy to standard pain rehabilitation helps adults with chronic pain. It is for patients at the Linköping pain clinic who have internet access.
Linköping, Östergötland CountyAges 18 years+ - NCT06869668Recruiting
Chronic low back pain and quality of life study
This study looks at how long-term back pain affects your daily life, physical abilities, and how you feel about moving. It aims to find links between pain, fear of movement, and overall well-being.
Istanbul, BuyukcekmeceAges 18–50 - NCT06963658Recruiting
Isometric Exercise and Pain Sensitivity in Chronic Low Back Pain
This study tests whether a simple, still (isometric) exercise can reduce how sensitive you are to pain. It is for adults with long-term low back pain who can safely do physical therapy exercises.
Bisha, 'Asir RegionAges 18 years+ - NCT06973837Recruiting
Brain study on chronic back pain and insomnia
This study looks at how the brain works in people with chronic low back pain and/or chronic insomnia. It compares these groups to healthy volunteers using MRI and pain tests.
LeuvenAges 18–60 - NCT07123233Recruiting
Cognitive behavioral treatment for chronic face and mouth pain
This trial tests a new cognitive-behavioral therapy (a type of talk therapy) for people with chronic orofacial pain – pain in the face, mouth, or jaw that has lasted for months. The goal is to learn skills to help manage pain and improve quality of life.
MilanAges 18–70 - NCT07247552Recruiting
Personalized rTMS for chronic pain
This study tests if personalized repetitive transcranial magnetic stimulation (rTMS), a non-invasive brain stimulation technique, can help reduce chronic pain. It aims to find out if targeting specific brain areas based on your pain patterns works better than standard treatment.
GistrupAges 18–80 - NCT07270588Recruiting
MobACT: Online support for chronic pain
This trial tests an internet-based program to help people manage chronic pain. You participate from home using a computer or tablet.
BolognaAges 18 years+ - NCT07280338Recruiting
Emotional intelligence and chronic face pain study
This study looks at how emotional intelligence (understanding and managing emotions) relates to chronic pain in the face or jaw. If you have temporomandibular dysfunction (TMD) or have no chronic pain, you may be able to join and help researchers learn more.
BrestAges 18 years+ - NCT07432841Recruiting
Personalized brain stimulation for chronic pain
This trial tests a personalized form of brain stimulation (high-definition tDCS) to treat chronic pain that has not improved with other treatments. If you have had pain for at least 6 months and it is still moderate to severe, this may be an option to explore.
MilanAges 18–75
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Common questions
- Are there clinical trials for chronic pain?
- Yes. Clin2 currently lists 828 recruiting chronic pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.