Clinical trials
Chronic pain clinical trials
Pain that lasts for months or longer, often after the original cause has healed. We’re tracking 793 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06973837Recruiting
Brain study on chronic back pain and insomnia
This study looks at how the brain works in people with chronic low back pain and/or chronic insomnia. It compares these groups to healthy volunteers using MRI and pain tests.
LeuvenAges 18–60 - NCT06963658Recruiting
Isometric Exercise and Pain Sensitivity in Chronic Low Back Pain
This study tests whether a simple, still (isometric) exercise can reduce how sensitive you are to pain. It is for adults with long-term low back pain who can safely do physical therapy exercises.
Bisha, 'Asir RegionAges 18 years+ - NCT06795243Recruiting
Physical therapy for endometriosis and exercise adherence
This study tests whether physical therapy (exercise for your muscles) can help with endometriosis symptoms and how well people stick with the program. If you have endometriosis and can do light strength exercises, you may be able to join.
SevilleAges 18 years+ - NCT05540548Recruiting
Podiatry assessment for balance and pain in chronic back pain
This study looks at whether a foot and posture specialist can help measure how balance relates to the pain you feel in chronic low back pain. It may help doctors better understand what to focus on for pain that lasts for months.
ValenciennesAges 18 years+ - NCT06153303Recruiting
Online therapy for endometriosis and chronic pain
This trial tests if an internet-based program based on acceptance and commitment therapy (ACT) can help people with endometriosis and chronic pain. It aims to improve daily functioning and quality of life.
Lund, Skåne CountyAges 18–65 - NCT05700279Recruiting
PTSD treatment to help prevent future chronic pain
This study tests whether treating post-traumatic stress disorder (PTSD) right when you come to the emergency room for new, acute pain can lower the chance you develop long-term (chronic) pain. It may help people whose pain and trauma symptoms start around the same time.
Chicago, IllinoisAges 18–70 - NCT06004804Recruiting
Psychological treatments for chronic pain in veterans
This study compares two group psychological treatments for chronic pain delivered over video conference. It aims to see if these treatments help reduce pain and improve quality of life for veterans.
West Los Angeles, CaliforniaAges 60–95 - NCT05986292RecruitingPhase 2
Study of new pain treatments for chronic pain
This study tests new treatments for people with chronic pain that has lasted at least 12 weeks. It aims to find better ways to reduce pain and improve quality of life.
Birmingham, AlabamaAges 18 years+ - NCT05701852Recruiting
Study brain scans during tasks in chronic nerve pain
This study looks at how brain activity changes in people with long-lasting nerve pain using an MRI scan while you do simple behavioral tasks. It may help researchers understand brain function in chronic neuropathic pain and how it affects day-to-day abilities.
ParisAges 18 years+ - NCT04880096Recruiting
Study of people living with chronic pain
This study follows people with long-term (chronic) pain to better understand their experience. It may help researchers evaluate what support or care could be more helpful for chronic pain patients.
Clermont-Ferrand, AURAAges 18 years+ - NCT07810218Recruiting
Personalized exercise for chronic pelvic pain
This study tests whether a smartphone app can give you personalized exercise recommendations to help reduce chronic pelvic pain, which may come from conditions like endometriosis or fibroids. You'll track your symptoms and activity daily, and the app will learn what works best for you.
New York, New YorkAges 18–55 - NCT06534372Recruiting
Factors affecting chronic pain after open-heart surgery
This study looks at factors that may lead to long-term pain after open-heart surgery. It follows patients who have coronary bypass or valve surgery to understand what might cause ongoing pain.
Ankara, AnkaraAges 18–80 - NCT07132762Recruiting
Shock wave therapy for chronic low back pain
This study tests whether adding a special sound wave therapy (called ESWT) to standard care (like exercise and education) can reduce pain and improve daily function in people with long-term low back pain. It is designed for people whose back pain does not have a specific known cause.
DenizliAges 18–65 - NCT06861920RecruitingPhase 4
NSAID use for painful periods to prevent chronic pelvic pain
This study tests whether using NSAIDs (like naproxen) for painful periods can help prevent chronic pelvic pain later on. It's for people with regular, painful periods who are otherwise healthy.
Evanston, IllinoisAges 18–35 - NCT06168058Recruiting
Pelvic vein embolization for chronic pelvic pain
This trial tests if blocking enlarged veins in the pelvis (called embolization) can reduce long-term pelvic pain that hasn't improved with other treatments. It may help women whose pain is worse when standing or walking and better when lying down.
Kansas City, KansasAges 18–75 - NCT07867808Enrolling by invitation
Magnetic therapy versus water therapy for chronic pelvic pain
This study compares two non-drug treatments—pulsed electromagnetic therapy and hydrotherapy (warm water therapy)—to see which one better relieves long-term pelvic pain in men. If you have chronic pelvic pain from non-bacterial prostatitis, this trial could help you find a new way to manage your symptoms.
AmmanAges 42–52 - NCT07833280Recruiting
Pelvic pain, movement, sleep, and quality of life in women
This study looks at how chronic pelvic pain affects movement, sleep, and daily life in women. It may help find better ways to support women with this condition.
Kırşehir, MerkezAges 18–65 - NCT07799857Recruiting
Light therapy for pelvic pain registry
This study tracks people getting light therapy inside the vagina for chronic pelvic pain. It helps doctors learn if this treatment works and who it helps most.
Melbourne, FloridaAges 18 years+ - NCT07787741Recruiting
Cervical Epidural Injection for Chronic Neck Pain
This study tests a cervical epidural block (an injection into the neck area) as a treatment for chronic neck pain. It aims to see if this injection can help reduce pain in people with nerve-related neck pain.
Adapazarı, SakaryaAges 18–55 - NCT07782099Recruiting
Breathing muscle function in chronic neck pain
This study compares breathing muscle function between people with chronic neck pain and healthy individuals. It aims to see if neck pain affects breathing muscles, which might lead to new treatments.
Kocaeli, DerinceAges 18–65 - NCT07756229Recruiting
Physiotherapy for long-term neck pain
This study looks at how physiotherapy affects brain activity and symptoms in people with chronic neck pain lasting more than 3 months. It aims to see if physiotherapy can help reduce pain and improve function.
San Sebastián, GuipuzcoaAges 18 years+ - NCT07741227Recruiting
Electric acupuncture for chronic neck pain
This study tests whether electric acupuncture can reduce stiffness and pain in the neck muscles. It may be a treatment option if you have had neck pain for at least 3 months and would like to try a non-drug approach.
Hong KongAges 18–65 - NCT07707609Recruiting
Pain and brain changes in chronic pancreatitis
This study looks at how chronic pancreatitis pain affects the nervous system and mental health. It aims to understand pain better and may help develop new ways to manage it.
Hyderabad, TelanganaAges 18–60 - NCT06641206Recruiting
Dexmedetomidine injection for chronic knee pain
This trial tests whether a single injection of dexmedetomidine into the knee joint can reduce chronic knee pain. It is for people who are not scheduled for knee surgery and have no serious health problems.
Tanta, El GharbyiaAges 40–75
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Common questions
- Are there clinical trials for chronic pain?
- Yes. Clin2 currently lists 793 recruiting chronic pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.