Clinical trials
Chronic pain clinical trials
Pain that lasts for months or longer, often after the original cause has healed. We’re tracking 828 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07225049Recruiting
Integrated treatment for PTSD and chronic pain
This study tests a combined therapy for people who have both PTSD and chronic pain. It aims to see if treating both conditions together is more helpful than treating them separately.
New York, New YorkAges 18 years+ - NCT07266103Recruiting
Personalized brain stimulation for chronic pain study
This study tests whether personalized sessions of repetitive transcranial magnetic stimulation (rTMS), a non-invasive brain stimulation technique, can help reduce chronic pain. It aims to understand how this treatment works and how it might be tailored to individuals.
GistrupAges 18–80 - NCT07287501Recruiting
Pain education and exercise for older adults with chronic pain
This trial is for older adults (65+). It combines pain science education with exercise to help manage chronic pain. You'll learn about how pain works and practice exercises designed to reduce pain and improve movement.
Salamanca, SalamancaAges 65 years+ - NCT07308873Recruiting
Gait and knee osteoarthritis pain study
This study looks at how walking patterns relate to knee pain from osteoarthritis. It aims to understand individual differences to improve future treatments.
Pittsburgh, PennsylvaniaAges 45–80 - NCT07318519Recruiting
Virtual reality for chronic cancer pain
This study tests whether virtual reality (VR) can help reduce chronic pain in people with cancer. If you have had cancer pain for at least three months and rate your pain as 4 or more out of 10, you may be able to join.
Washington D.C., District of ColumbiaAges 18 years+ - NCT07325110Recruiting
Teens with chronic pain: yoga in occupational therapy
This study looks at whether adding yoga to occupational therapy helps teens with chronic pain better understand their body's signals. It aims to improve daily function and well-being.
Hartford, ConnecticutAges 11–21 - NCT00499317Recruiting
Genetic study of chronic pelvic pain and bladder symptoms
This study looks for genetic (inherited) factors behind chronic pelvic pain and related urinary and sexual symptoms. You may be able to help researchers by providing a few samples and answering short questions, which could improve understanding of these conditions.
Boston, MassachusettsAges Any age - NCT07404618Recruiting
Video pain relief study for older adults
This study tests a video program to help older adults with ongoing muscle or joint pain learn skills to manage pain and improve daily life. It may be a good fit if pain has been bothering you most days for at least 3 months and gets in the way of your normal activities.
Providence, Rhode IslandAges 55 years+ - NCT07425691Recruiting
A program for teens with chronic pain and their parents
This study offers a program to help teens with chronic pain learn skills to manage their pain and improve daily life. The program includes both the teen and a parent, so it's a team effort.
Palo Alto, CaliforniaAges 10–17 - NCT07432425Recruiting
Exercise programs for chronic neck pain
This study compares different exercise programs to see which one improves physical and mental health in people with chronic neck pain. You may be eligible if you have had neck pain for at least 3 months and it is moderate to severe, but you haven't been in a recent neck pain rehab or exercise program.
Ankara, AltindagAges 20–65 - NCT07491549Recruiting
Pain education group therapy for chronic pain
This trial tests if group education about pain can help people with chronic pain move more, feel better, and have less fear of movement. It's looking for adults whose pain has lasted more than 3 months and affects their daily life.
Tartu, TartuAges 16–65 - NCT07498491Recruiting
Weighted blanket study for adults with ongoing pain
This study tests whether using a weighted blanket (10–25 pounds) while sleeping can help adults with chronic pain. If you join, you'll use the blanket every night for about 5 weeks and complete simple online questionnaires.
Portland, OregonAges 18 years+ - NCT07525557Recruiting
Understanding Fear and Disability in Long-Term Neck Pain
This study explores how fear of movement, pain, and daily difficulties relate to each other in people with chronic neck pain lasting 3+ months. Understanding these connections may help improve future treatment approaches.
Samsun, SamsunAges 18 years+ - NCT07578376Recruiting
Pain Relief Program for Cancer Survivors
This study tests an online pain-management program called Empowered Relief® designed specifically for cancer survivors dealing with chronic pain. You'll complete surveys and attend virtual classes to learn techniques that may help reduce your daily pain.
Tulsa, OklahomaAges 18–120 - NCT07587047RecruitingPhase 1
Stem cell study for chronic lower back pain
This study tests a stem cell treatment for people with ongoing lower back pain. It aims to see if the therapy can help reduce pain and improve your quality of life.
Winter Park, FloridaAges 18–85 - NCT07600892Enrolling by invitation
Pain-at-Work Toolkit for managing chronic pain at work
This study tests a toolkit designed to help working adults manage chronic pain while on the job. The toolkit aims to make work more manageable and enjoyable for people living with ongoing pain.
Nottingham, NottinghamshireAges 18 years+ - NCT07485426Enrolling by invitation
Activity and pain management for teens with chronic pain
This study tests an online program to help teens manage chronic pain and improve daily functioning. It uses acceptance and commitment therapy (ACT) to build coping skills and reduce suffering.
Linköping, Östergötland CountyAges 13–19 - NCT07432685Enrolling by invitation
Can movement predict chronic pain after combat limb injuries?
This study is looking for people with combat-related arm or leg injuries to see if how they move can predict long-term pain. Researchers hope to better understand who might develop chronic pain and help improve treatment.
LvivAges 18–50 - NCT07331766Enrolling by invitation
Collaborative care for chronic pain patients
This trial tests a team-based treatment approach for people with chronic pain. You'll work with at least two pain clinic specialists to create a care plan that fits your needs.
Ottestad, InnlandetAges 18 years+ - NCT07011537Enrolling by invitation
Digital health program and TENS for chronic low back pain
This trial tests a digital health program combined with a TENS device (a small device that sends gentle electrical pulses to help with pain) for people with ongoing low back pain. It compares this approach to standard care, and you would be randomly assigned to one of the two groups.
Eden Prairie, MinnesotaAges 18 years+ - NCT06628180Enrolling by invitation
Low-intensity focused ultrasound for chronic pain
This study tests a noninvasive treatment called low-intensity focused ultrasound (LIFU) to help relieve chronic pain. It may be an option if you have had moderate to severe pain for at least 3 months.
Roanoke, VirginiaAges 18–65 - NCT06407115Enrolling by invitation
Pain care support for rural patients
This study tests a nurse-led program to help people living in rural areas manage chronic pain. You'll work with a care manager who can support your pain treatment goals.
Winston-Salem, North CarolinaAges 18 years+ - NCT06019793Enrolling by invitation
Recording brain signals during deep brain stimulation for pain
This study tests whether recording brain activity during deep brain stimulation (DBS) for chronic pain can help improve future treatments. It is for people with long-lasting, severe pain that hasn't been helped by other treatments.
Phoenix, ArizonaAges 22 years+ - NCT05477004Enrolling by invitation
Study of ketamine infusions for ongoing chronic pain
This study is observing people with chronic pain who are getting ketamine infusions at Stanford. You may help by completing email surveys about how you feel, which can help the team understand the treatment’s impact.
Stanford, CaliforniaAges 18 years+
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Common questions
- Are there clinical trials for chronic pain?
- Yes. Clin2 currently lists 828 recruiting chronic pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.