Clinical trials
Chronic pain clinical trials
Pain that lasts for months or longer, often after the original cause has healed. We’re tracking 828 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06052384Recruiting
Better sleep care for chronic pain patients
This study tests whether adding a sleep specialist to your pain care team can help you feel better. If you have chronic pain (lasting over 3 months) and are now seeing a pain doctor for the first time, you may be able to join.
Le Puy-en-VelayAges 18 years+ - NCT06104384Recruiting
Chronic pain patients with injury claims study
This study looks at injury claims from people with chronic pain to better understand their experiences. It may help improve care for others with similar conditions.
Surrey, British ColumbiaAges 20–99 - NCT07199361Recruiting
Magnetic stimulation for chronic pain after injury or surgery
This study tests a non-invasive magnetic device placed on the skin to see how it relieves chronic pain caused by a past injury or surgery. It may help people who have had pain for at least three months and take medication for it.
Miami, FloridaAges 19–80 - NCT07339631RecruitingPhase 1
Sodium Aescinate for Chronic Low Back Pain in Adults
This study tests an injectable medication called sodium aescinate (derived from horse chestnut) for people with chronic low back pain. It aims to see if it helps reduce pain and is safe to use.
Xi'an, ShaanxiAges 18–65 - NCT06835608Recruiting
Schroth exercise for kyphosis and chronic neck pain
This study tests whether an exercise program called Schroth (which strengthens back muscles) can improve your posture, reduce neck pain, and make daily activities easier. It is for people with a hunched upper back (kyphosis) and long-lasting neck pain.
Ankara, ÇankayaAges 20–50 - NCT07529392Recruiting
Ear nerve stimulation plus rehabilitation for chronic back pain
This trial tests a non-surgical treatment that stimulates a nerve in your ear while you do rehabilitation exercises to reduce chronic back pain. It may help if you've had pain for more than 6 months and pain medications aren't working well enough.
Baden, Lower AustriaAges 30–65 - NCT07301632RecruitingPhase 2
MDMA for severe chronic nerve pain
This trial tests if MDMA, combined with psychotherapy, can help people with severe chronic nerve pain that hasn't improved with standard treatments. You'll receive either MDMA or a placebo to see if it safely reduces pain and improves your quality of life.
Toronto, OntarioAges 18 years+ - NCT07733583Recruiting
Pelvic floor therapy and exercise for endometriosis pain
This study tests whether a special type of physical therapy (pelvic floor therapy) combined with exercise can help reduce chronic pelvic pain in women with endometriosis. It aims to see if these treatments improve pain, daily function, and quality of life.
Porto Alegre, Rio Grande do SulAges 18–45 - NCT05701982Recruiting
Walking plus Tai Chi coach via video for COPD and pain
This study tests whether a phone/computer program that combines walking training with Tai Chi improves physical function (how well you move) in people who have COPD and long-term body or muscle pain. It may help you build strength, balance, and safer movement—especially if pain makes activity hard.
Boston, MassachusettsAges 40–100 - NCT07096661Enrolling by invitation
Pain education for labor and postpartum pain
This study tests a way of teaching about pain (called pain science education) to help healthcare professionals better support women during labor and after birth. If you are a healthcare professional who works with pregnant or new mothers, this trial may be for you.
BournemouthAges Any age - NCT06468904Recruiting
Neck exercises for hand strength in chronic neck pain
This trial tests whether special neck exercises can improve hand grip strength in people with long-term neck pain caused by muscle knots. If you have chronic neck pain and hand weakness, this study may help you get stronger while reducing pain.
GizaAges 20–45 - NCT06707870Recruiting
Neck exercises for chronic pain relief
This trial compares two different treatments for long-lasting neck pain: a special exercise that helps with neck posture (cervical retraction) and a gentle manual therapy technique (facet oscillatory mobilization). It aims to find which method is better at reducing pain and improving neck movement.
Peshawar, KPKAges 35–50 - NCT07531537Recruiting
Breathing exercises versus neck muscle training for neck pain
This study compares two types of exercises—breathing exercises and deep neck muscle training—to see which works better for people with long-term neck pain. You'll do one type of exercise program to help relieve your pain and improve function.
ZagazigAges 18–35 - NCT06671925Recruiting
Support program for chronic pain and loneliness in older adults
This trial tests a program led by community health workers to help older adults manage chronic pain and reduce loneliness. It aims to improve your well-being through support and guidance.
Ann Arbor, MichiganAges 60 years+ - NCT06246929Recruiting
Healthy aging for Black adults with chronic pain and memory concerns
This study tests a program to help Black adults aged 50+ manage chronic pain and early memory changes. It compares two approaches to see which works better for improving daily life and thinking skills.
Boston, MassachusettsAges 50 years+ - NCT07026019Recruiting
Exercise for chronic mechanical neck pain
This study tests whether a home exercise program can help people with long-term neck pain caused by muscle tightness or arthritis in the neck joints. It is designed for people who cannot easily visit a clinic due to disability, living in crowded cities, or busy schedules.
Lahore, Punjab ProvinceAges 18–45 - NCT07103135RecruitingPhase 1
Testing an accelerated TMS for chronic pain
This study tests an accelerated form of Transcranial Magnetic Stimulation (TMS) — a non-invasive treatment that uses magnetic pulses to stimulate the brain — to see if it can reduce chronic pain. If you have long-term pain that hasn't responded well to at least two medications, this trial might be a good option for you.
Minneapolis, MinnesotaAges 18 years+ - NCT07383558Recruiting
Adding nerve treatment for chronic heel pain
This trial tests if adding a nerve treatment (pulsed radiofrequency of the sural nerve) to standard care helps people with long-lasting heel pain. It may reduce pain and improve function.
AnkaraAges 18–65 - NCT07497425Recruiting
Exercise and Immune Response in Chronic Back Pain
This study looks at how a single session of exercise affects your immune system and nervous system. It may help researchers find new ways to treat chronic low back pain.
Montreal, QuebecAges 18–75 - NCT07244861Enrolling by invitation
TENS for neck muscle stiffness and pain
This study tests whether a gentle electrical stimulation device (TENS) applied to the neck can reduce muscle stiffness and pain in people with ongoing neck pain. If you have had neck pain for at least 6 weeks and are willing to avoid certain medications the day before, you may be able to join.
ErzurumAges 18–50 - NCT06547723Enrolling by invitation
Mindfulness for chronic pain in older adults
This study tests if a program called Mindfulness-Based Stress Reduction (MBSR) helps older adults reduce chronic pain. If you are 65 or older and can read Persian, you may be able to join this study that teaches simple mindfulness techniques to change how you relate to your pain.
Mashhad, Razavi Khorasan ProvinceAges 65–90 - NCT06443164Enrolling by invitation
Chronic Pain Treatment Before Gender-Affirming Surgery
This study tests a one-session pain management class called Empowered Relief for people with chronic pain who are planning gender-affirming surgery. The goal is to see if learning these skills before surgery helps with pain afterward.
Portland, OregonAges 18–100 - NCT06351046Recruiting
Preventing chronic pain from getting worse
This trial tests a virtual reality program to see if it can help prevent long-term pain from becoming more severe. You may be eligible if you have had pain for at least 3 months and rate your average pain as moderate or higher.
Copenhagen, København Ø.Ages 18 years+ - NCT07694882Recruiting
Gentle pressure techniques for chronic neck pain
This study tests two different types of gentle pressure techniques (myofascial release) to see which one helps relieve long-term neck pain and improve everyday function. It is for people with chronic neck pain that isn't caused by a specific injury or disease.
Famagusta, HatayAges 18–45
Hear when a new Chronic pain trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for chronic pain?
- Yes. Clin2 currently lists 828 recruiting chronic pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.