Clinical trials
Chronic Postoperative Pain clinical trials
Below are recruiting chronic postoperative pain clinical trials, each written for real people, not researchers. We’re tracking 296 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07329309Recruiting
Breathing exercises for pain after cesarean
This study tests if a gentle breathing technique called Pranayama can help reduce pain after a planned cesarean. It compares the breathing exercise to usual care to see if it improves recovery.
Konya, KonyaAges 18–35 - NCT07180498Recruiting
Tea tree vs chlorhexidine mouthwash after wisdom tooth removal
This study compares a tea tree oil mouthwash and a standard chlorhexidine mouthwash to see which helps better after wisdom tooth removal. It may help you heal faster and with less discomfort.
SanliurfaAges 18–65 - NCT07102446Recruiting
Opioid safety program for chronic pain patients without cancer
This trial tests a program to help manage opioid use safely for people with chronic non-cancer pain. If you take opioids for long-term pain and do not have cancer, this study may help improve your care.
Seoul, SeoulAges 19–79 - NCT07002541Recruiting
Nerve block comparison for breast surgery pain
This study tests two different nerve-block methods (PECS-II and ESP) to see which better reduces painkiller use during breast surgery. A special monitor guides how much pain medicine you need. The goal is to help you recover with less opioid side effects.
IstanbulAges 18–80 - NCT05058287RecruitingPhase 3
Steroid shot during low-back surgery
This trial tests whether using a steroid medicine (a steroid shot) around the time of low-back decompression surgery improves pain and recovery. It is for adults having a limited-area laminectomy, and it compares steroid use versus not using it.
New York, New YorkAges 18–85 - NCT06757023Recruiting
Acupuncture for better sleep after breast cancer surgery
This study tests if thumbtack needle therapy (a type of acupuncture) can improve sleep and recovery in women after breast cancer surgery. If you're between 18 and 55 and having breast cancer surgery with general anesthesia, you may be eligible.
Xiamen, FujianAges 18–55 - NCT07326774Recruiting
Ultrasound-guided pain block for back surgery recovery
This trial tests whether a special pain block (Quadro-Iliac Plane Block) given before back surgery can reduce pain after the operation. The goal is to help patients feel more comfortable and need fewer painkillers.
Istanbul, IstanbulAges 18–65 - NCT06087510RecruitingPhase 4
Different doses of esketamine and dexmedetomidine for pain after scoliosis surgery
This trial tests two different doses of esketamine and dexmedetomidine to see which provides better pain relief after scoliosis correction surgery. It aims to improve your recovery and long-term outcomes.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06810336RecruitingEarly Phase 1
Pain control after brain surgery: methadone vs remifentanil
This trial compares two medicines, methadone and remifentanil, to see which one works better for pain after brain surgery. It may help improve your recovery and comfort.
Charlottesville, VirginiaAges 18–65 - NCT07745127Recruiting
Nasal stitch versus packing after nose surgery
This study compares two ways to stop bleeding after nasal surgery (septoplasty): using a special stitch inside the nose versus using nasal packing. It aims to see which method is more comfortable and effective for patients like you.
Islamabad, FedralAges 18–50 - NCT07632833Recruiting
Comfort tote for teens recovering from spine surgery
This study tests whether giving teens a special comfort tote with calming items helps them feel better and recover more smoothly after surgery for scoliosis. It is for patients aged 10 to 21 who are having spinal fusion at a specific hospital.
New York, New YorkAges 12–21 - NCT07491146RecruitingPhase 2
Study of HSK55718 for pain after abdominal surgery
This trial tests a new medicine, HSK55718, to see if it safely reduces pain after planned abdominal surgery. It is for adults who have moderate or severe pain after surgery and are otherwise in good health.
Changsha, HunanAges 18 years+ - NCT05929755RecruitingPhase 4
Depo-Medrol after lumbar surgery through the psoas muscle
This trial studies whether a steroid shot called Depo-Medrol, given after a specific type of lower-back surgery, can improve recovery and outcomes. It’s only for people who are having a certain lumbar fusion procedure at specific spinal levels.
Farmington, ConnecticutAges 18–75 - NCT06077422Enrolling by invitationPhase 2/Phase 3
Comparing two pain blocks for heart surgery recovery
This trial compares two types of pain blocks (Exparel vs. Marcaine) given during heart surgery to see which one provides better pain relief. If you are scheduled for a heart surgery through a small or full chest incision, you may be able to join.
New Brunswick, New JerseyAges 18 years+ - NCT07790471Recruiting
Recovery checklists after cesarean delivery
This study looks at how following a recovery plan after a planned cesarean birth affects how well mothers feel and recover. It involves filling out questionnaires before and after the surgery to track your recovery.
Bursa, NilüferAges 18 years+ - NCT06495632RecruitingPhase 4
Scheduled or as-needed pain medicine after surgery?
This study compares taking pain medicine on a fixed schedule versus only when you need it after common outpatient surgeries. It aims to find which approach works better for controlling pain and reducing side effects.
Fayetteville, North CarolinaAges 18–65 - NCT07400146RecruitingPhase 4
Numbing medicine for pain relief in laparoscopic surgery
This trial tests if numbing medicine (bupivacaine with epinephrine) placed over the diaphragm during laparoscopic surgery can reduce shoulder and other pain. It may help patients undergoing gynecologic laparoscopy recover more comfortably.
Los Angeles, CaliforniaAges 18 years+ - NCT06761989Recruiting
Comparing two ways to control pain after Whipple surgery
This study compares two ways to manage pain after a Whipple procedure: one is a shot of morphine into the fluid around the spine, and the other is a small tube placed under the skin at the surgical cut that delivers pain medicine continuously. The goal is to see which method provides better pain relief and recovery.
Seoul, SeoulAges 19 years+ - NCT06053476Recruiting
Chest tube and pain care after lung surgery for collapsed lung
This study compares two ways to manage the chest tube and pain after surgery for a collapsed lung (pneumothorax). The goal is to find out which approach helps patients recover faster and with less pain.
VeldhovenAges 16 years+ - NCT07739277Recruiting
Comparing two ways to give a chest wall pain block for breast surgery
This study compares two ways of giving a numbing injection (a nerve block) to the side of the chest wall for pain relief after breast surgery. The goal is to see which method works better for reducing pain and the need for pain medicine.
Ankara, Yenimahalle\AnkaraAges 18–65 - NCT07721571Recruiting
Numbing medicine around drainage tube for kidney stone surgery pain
This study tests whether injecting a local numbing medicine around the nephrostomy tube after kidney stone surgery can reduce pain after the procedure. If you are having this surgery, it may help you feel more comfortable during recovery.
Çorum, ÇorumAges 18–75 - NCT06779396RecruitingPhase 4
Scalp injection to reduce pain after brain surgery in children
This trial tests if injecting a mix of two medicines (triamcinolone and ropivacaine) into the scalp before brain surgery can lower pain in children afterward. It compares this to standard care to see if it helps kids recover more comfortably.
Beijing, Beijing MunicipalityAges 2–12 - NCT06320041RecruitingPhase 4
Oliceridine for pain after orthopedic surgery
This trial tests a new painkiller called oliceridine for moderate to severe pain after orthopedic surgery. It may help you recover more comfortably with fewer side effects.
Yiwu, ZhejiangAges 18–100 - NCT06743802RecruitingPhase 4
Coenzyme Q10 for pain after lung surgery
This trial tests if taking coenzyme Q10 before and after thoracoscopic lung surgery can reduce pain. It may help you recover more comfortably.
Chongqing, Chongqing MunicipalityAges 18–75
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Common questions
- Are there clinical trials for chronic postoperative pain?
- Yes. Clin2 currently lists 296 recruiting chronic postoperative pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic postoperative pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic postoperative pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Postoperative Pain
- Postoperative Pain, Acute
- Postoperative Pain Management
- Total Knee Arthroplasty (Postoperative Pain)
- POSTOPERATIVE DELIRIUM AND POSTOPERATIVE COGNITIVE DECLINE
- Postoperative Pain After Endodontic Treatment
- Postoperative Pain Following Knee Arthroplasty
- Postoperative Pain Management in Oral Surgery
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.