Clinical trials
Chronic Postoperative Pain clinical trials
Below are recruiting chronic postoperative pain clinical trials, each written for real people, not researchers. We’re tracking 297 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06743802RecruitingPhase 4
Coenzyme Q10 for pain after lung surgery
This trial tests if taking coenzyme Q10 before and after thoracoscopic lung surgery can reduce pain. It may help you recover more comfortably.
Chongqing, Chongqing MunicipalityAges 18–75 - NCT06779396RecruitingPhase 4
Scalp injection to reduce pain after brain surgery in children
This trial tests if injecting a mix of two medicines (triamcinolone and ropivacaine) into the scalp before brain surgery can lower pain in children afterward. It compares this to standard care to see if it helps kids recover more comfortably.
Beijing, Beijing MunicipalityAges 2–12 - NCT06817239Recruiting
Low-dose esketamine for preventing confusion after surgery in older adults
This study tests whether a low dose of the medicine esketamine can help prevent confusion after surgery in older adults at higher risk. You may qualify if you are 65 or older, planning a major non-cardiac surgery, and have certain health conditions like high blood pressure or diabetes.
Fuzhou, FujianAges 65–90 - NCT07232108Recruiting
Pain medicine options for recovery after laparoscopic hysterectomy
This study compares two types of pain medicine given during laparoscopic hysterectomy: one is a morphine shot into the spine, the other is numbing medicine injected around the surgery cuts and into the belly. The goal is to see which helps you recover better and with less pain.
ErzurumAges 18–65 - NCT07396753Recruiting
Nerve block to reduce opioid use after kidney donor surgery
This study tests a nerve block called Transversalis Fascia Plane Block to see if it lowers the amount of strong pain medicine (opioids) needed after a kidney donor surgery. It may help you have less pain and fewer side effects.
Istanbul, ZeytinburnuAges 18–80 - NCT06054802Enrolling by invitation
Sleep and pain after spine surgery in teens
This study looks at how sleep quality before and after spine surgery affects pain recovery. It uses text messages to check in with participants, so a mobile device is needed.
Columbus, OhioAges 10–18 - NCT05231460Enrolling by invitationPhase 4
Pain plan study for people before bariatric surgery
This study tests a specific pain-management plan for people who are scheduled for sleeve gastrectomy (done by laparoscopy or robotics). The goal is to find how to control pain safely around the time of surgery while avoiding certain risks and medication issues.
Phoenix, ArizonaAges 18 years+ - NCT07578545Recruiting
Pain management after minimally invasive chest surgery
This study tests whether combining a specific type of chest surgery (using small cameras) with numbing injections around nerves reduces pain and the need for strong pain medications after surgery. Researchers want to see if this approach helps patients recover better with less opioid use.
Antalya, MuratpaşaAges 18–75 - NCT06978179Recruiting
Nerve blocks for pain after lower belly surgery
This trial compares two types of nerve blocks (QL block vs TAP block) to see which one provides better pain relief after lower abdominal surgery. If you are having this surgery, you may be able to join and receive one of these blocks to help manage your pain.
SohagAges 18–65 - NCT07104825Recruiting
Nerve block for pain after weight loss surgery
This trial tests if a nerve block can help control pain after gastric bypass or sleeve gastrectomy. The goal is to reduce the need for strong pain medicines and improve recovery.
Evanston, IllinoisAges 18–90 - NCT03737292RecruitingPhase 4
Numbing medicine for chest surgery pain after small lung operations
This trial tests whether a long-lasting numbing shot (liposomal bupivacaine) works better than a regular numbing shot (plain bupivacaine) for pain after minimally invasive chest surgery. It may help you have less post-surgery pain and potentially use less pain medication.
Hershey, PennsylvaniaAges 18 years+ - NCT04860141RecruitingPhase 4
Gabapentin before wisdom tooth removal to reduce pain
This trial tests whether taking gabapentin before extracting a wisdom tooth helps with pain and comfort after the procedure. It may help people who need a third-molar removal, if they meet the safety and health requirements.
Loma Linda, CaliforniaAges 18–59 - NCT06467409RecruitingPhase 2
Study of LPM3480392 for pain after knee surgery
This trial tests an injection called LPM3480392 to see if it safely reduces moderate to severe pain after knee replacement or ligament repair surgery. It aims to help people who need strong pain relief after this type of surgery.
WuhanAges 18 years+ - NCT07615595Enrolling by invitationPhase 4
Dexamethasone to reduce side effects from spinal anesthesia during cesarean delivery
This study tests whether giving a steroid medication (dexamethasone) before spinal anesthesia can reduce uncomfortable side effects like nausea, vomiting, and low blood pressure during planned cesarean delivery. The goal is to help you feel better during and after your surgery.
Ho Chi Minh City, Ho Chi MinhAges 18 years+ - NCT06978335Enrolling by invitation
Acupoint stimulation for better wound pain relief after surgery
This study tests if gentle stimulation of acupoints (like acupressure or a small device) can ease pain from a surgical wound. It is for adults who are having a surgery with a long incision and will be using a pain pump afterward.
Taipei, Peitou DistAges 18 years+ - NCT07568093Recruiting
Music therapy to reduce agitation after abdominal surgery
This study tests whether listening to music after abdominal surgery can help reduce agitation and anxiety during recovery. Researchers will compare patients who receive music therapy with standard care to see if it improves comfort and outcomes.
Hanover, Lower SaxonyAges 18 years+ - NCT07720739Recruiting
Adding morphine to a spine block for belly surgery pain
This study tests whether adding a small dose of morphine to a numbing injection near the spine (called erector spinae plane block) provides better pain relief after midline belly surgery. It may help reduce the need for other pain medicines and improve recovery.
SohagAges 18–60 - NCT05272280Recruiting
Ultrasound nerve blocks for pain after gallbladder surgery
This trial compares two ultrasound-guided nerve block techniques to control pain after laparoscopic gallbladder (cholecystectomy) surgery. It may help by finding which method gives better pain relief with fewer side effects.
Asyut, Assiut, Asyut Governorate, Egypt,Ages 18–65 - NCT05985629RecruitingPhase 4
Numbing shot behind the knee for ACL surgery pain
This study tests whether an extra numbing shot (called IPACK) behind the knee helps reduce pain and the need for strong pain medicine after ACL reconstruction surgery. It's for patients who are having their first ACL surgery and are not using a donor graft.
Maywood, IllinoisAges 16 years+ - NCT06728371RecruitingPhase 3
IV methadone for pain after heart surgery
This trial tests if methadone given through a vein can control pain better after heart surgery done through a breastbone incision. It may be an option for adults having planned heart surgery who are expected to wake up and breathe on their own within 12 hours.
Hong KongAges 18 years+ - NCT07315308Recruiting
Nerve block before heart surgery and painkiller use
This study tests whether a numbing injection in the chest before heart surgery can reduce the amount of pain medicine needed during the operation. It may help you manage pain better and recover more comfortably.
Gaziantep, SahinbeyAges 18–65 - NCT07658521Enrolling by invitation
Nerve blocks for pain after heart bypass surgery
This study tests whether adding two numbing injections (nerve blocks) to standard care provides better pain relief after heart bypass surgery. It is for adults having planned surgery and compares pain scores and recovery.
Cairo, Cairo GovernorateAges 18–75 - NCT06886932Recruiting
Pain education after rotator cuff surgery
This trial tests if learning about pain before and after rotator cuff repair helps people recover better. It might help you if you have a medium-sized tear and are planning surgery.
KaramanAges 40–75 - NCT07394816Recruiting
Can ultrasound-guided pain blocks reduce lung complications after abdominal surgery?
This study tests whether using ultrasound-guided pain blocks (fascial plane blocks) during major abdominal surgery can reduce lung complications after surgery, especially in older adults. It may offer better pain control and faster recovery.
Yenimahalle, AnkaraAges 65 years+
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Common questions
- Are there clinical trials for chronic postoperative pain?
- Yes. Clin2 currently lists 297 recruiting chronic postoperative pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic postoperative pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic postoperative pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Postoperative Pain
- Postoperative Pain, Acute
- Postoperative Pain Management
- Total Knee Arthroplasty (Postoperative Pain)
- POSTOPERATIVE DELIRIUM AND POSTOPERATIVE COGNITIVE DECLINE
- Postoperative Pain After Endodontic Treatment
- Postoperative Pain Following Knee Arthroplasty
- Postoperative Pain Management in Oral Surgery
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.