Clinical trials
Chronic Spinal Pain clinical trials
Below are recruiting chronic spinal pain clinical trials, each written for real people, not researchers. We’re tracking 253 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06053242RecruitingPhase 1/Phase 2
Stem cell injection for long-term low back pain
This trial tests a new stem cell injection (CELZ-201-DDT) into a muscle to treat chronic lower back pain that hasn't improved with standard treatments. It aims to see if the injection is safe and effective for people aged 18 to 80 with moderate to severe back pain.
Aventura, FloridaAges 18–80 - NCT06438471RecruitingPhase 1
Study of a new drug for nerve pain after spinal cord injury
This trial tests an experimental pill for people with spinal cord injury who have long-term nerve pain. It aims to see if the drug can reduce pain and be safe.
Augusta, GeorgiaAges 18 years+ - NCT05986370Recruiting
Study on back pain and spinal manipulation
This trial tests whether spinal manipulation therapy (a type of hands-on treatment) can help people with long-term low back pain. It also compares their results to healthy volunteers of the same age and sex.
Trois-Rivières, QuebecAges 18–60 - NCT04273828Recruiting
Study of muscle changes in chronic low back pain surgery
This study looks at how muscle degeneration relates to nerve-related symptoms in people with chronic low back pain. You may be eligible if you’ve tried non-surgical care but still need surgery to relieve nerve pressure.
São Paulo, São PauloAges 18 years+ - NCT06818175Recruiting
Study of back muscle tissue and treatment for low back pain
This study looks at the tissue in your lower back using ultrasound and physical exams. It tests a treatment to see if it helps people with new or long-term low back pain, and also compares results to people without pain.
Blacksburg, VirginiaAges 18–50 - NCT07161661Recruiting
Osteopathic treatment for chronic low back pain in veterans
This trial tests whether adding osteopathic manipulative treatment (OMT) to standard VA care helps reduce chronic low back pain. OMT involves a healthcare provider using their hands to move and stretch muscles and joints.
Hines, IllinoisAges 18 years+ - NCT06620133Recruiting
Pain education and goal setting for chronic low back pain
This trial tests whether learning about pain and setting your own exercise goals helps people with long-term low back pain become more active. You will receive online sessions and support to safely increase your physical activity.
Sydney, New South WalesAges 18 years+ - NCT07685340Recruiting
Cupping vs Massage Tool for Chronic Low Back Pain
This trial tests two hands-on therapies—dry cupping and a special massage technique—to see which works better for long-term low back pain caused by muscle knots. You may be able to join if your pain has lasted over 3 months and you have trigger points.
Rawalpindi, Punjab ProvinceAges 25–45 - NCT05885061Recruiting
Spinal cord stimulation study for adults with chronic pain
This study looks at how spinal cord stimulation affects chronic pain in adults who already have the device implanted. It may help researchers understand who benefits most and how stable pain and treatments need to be to measure results.
AarhusAges 18–99 - NCT06587607Recruiting
VR mindfulness training for veterans with spinal cord injury
This study tests whether mindfulness training with virtual reality can help veterans with spinal cord injury manage chronic pain. It is done from home using a VR headset and group video calls.
Houston, TexasAges 18 years+ - NCT07719699Recruiting
Vibration and Pilates for chronic low back pain
This study tests if whole-body vibration or Pilates exercises can reduce pain and improve balance and movement in people with long-lasting low back pain. It aims to find a helpful treatment for chronic back pain that has lasted more than 12 weeks.
Lahore, Punjab ProvinceAges 18–40 - NCT05757609Recruiting
Brain stimulation therapy for chronic low back pain
This trial tests whether a non-invasive brain stimulation treatment can improve physiotherapy results for people with long-lasting low back pain. You may be asked to do questionnaires and follow a treatment plan, and some people may be able to reduce pain or improve function.
GenevaAges 18–65 - NCT07470307Recruiting
Exercise for chronic low back pain: Pilates vs. strength training
This trial compares dynamic lumbar strengthening exercises to Pilates, both combined with myofascial release, for people with ongoing low back pain. It aims to find which approach works better for reducing pain and improving function.
Lahore, Punjab ProvinceAges 25–35 - NCT07610044Enrolling by invitation
Pelvic Floor vs. Swiss Ball Exercises for Chronic Low Back Pain
This study tests two exercise approaches—pelvic floor exercises and Swiss ball exercises—to see which better reduces long-term lower back pain in women. Both aim to strengthen core muscles that support your spine.
Lahore, Punjab ProvinceAges 18–35 - NCT07403331Recruiting
Nerve pain in legs: spinal cord stimulation plus team care
This trial tests a treatment bundle that combines a spinal cord stimulator (a device that sends mild electrical pulses to your spine to block pain signals) with a team of specialists (like a psychologist and physical therapist) to reduce chronic nerve pain in the legs and improve your ability to move and function.
OsloAges 18–60 - NCT06113185Recruiting
Pain Scale Study for Low Back Pain
This study tests a pain scale for people with long-term low back pain. It is a questionnaire study, not a treatment trial, so you will fill out forms about your pain.
Istanbul, None SelectedAges 18–55 - NCT07125027Recruiting
A mind-body program for leg pain from back issues
This trial tests a program called Move-MORE that combines movement and mindfulness to help people with long-lasting leg pain caused by a nerve problem in the lower back. It involves daily activities, weekly virtual group meetings, and tracking your progress with a wearable device.
Portland, OregonAges 18–66 - NCT06944730Recruiting
Trunk muscle training for better movement and balance in low back pain
This study tests whether trunk muscle training can improve the quality of your movements and balance if you have chronic low back pain. It is designed for people with moderate pain and no other major health issues.
Hong KongAges 18–55 - NCT07248813Recruiting
Home-based rehab program for chronic low back pain
This trial tests a telerehabilitation program you can do from home using a smartphone or computer. It aims to improve function and reduce pain for people with chronic low back pain compared to usual care.
México, TexcocoAges 18–60 - NCT07507604Recruiting
Spinal Adjustment and Pain Relief in Chronic Low Back Pain
This study tests whether a brief hands-on spinal adjustment can affect pain and inflammation markers in people with long-term low back pain. It aims to see if psychological factors like expectations influence how well the treatment works.
Biała Podlaska, Lublin VoivodeshipAges 18–65 - NCT04142177Recruiting
Test which pain treatments work best for chronic low back pain
This study compares how well different pain treatments reduce low back pain and improve daily life. You may be asked to start or continue care through the VA and attend in-person sessions while completing pain and activity questionnaires.
Phoenix, ArizonaAges 18 years+ - NCT06310096Recruiting
Stretching for chronic low back pain
This study tests whether a special stretching technique for the connective tissue in your lower back can help reduce pain and improve function in people with chronic low back pain (pain lasting 3 months or more). You would attend physiotherapy sessions and do regular stretches.
AnkaraAges 20–60 - NCT06814808Enrolling by invitation
Comparing three treatments for chronic neck pain
This study compares three different treatments for chronic neck pain caused by trigger points (tender knots in muscles). It aims to find which approach works best for pain relief and improved function.
Istanbul, ZeytinburnuAges 18–65 - NCT07688915Recruiting
High-intensity laser vs. steroid injection for chronic back and leg pain from a herniated disc
This study compares two treatments for long-lasting low back and leg pain caused by a herniated disc: high-intensity laser therapy and a steroid shot near the spine. Researchers want to see which option works better to reduce pain.
AnkaraAges 18–65
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Common questions
- Are there clinical trials for chronic spinal pain?
- Yes. Clin2 currently lists 253 recruiting chronic spinal pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic spinal pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic spinal pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.