Clinical trials
Chronic Spinal Pain clinical trials
Below are recruiting chronic spinal pain clinical trials, each written for real people, not researchers. We’re tracking 253 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05196503RecruitingPhase 3
PRF gel in spine surgery to reduce nerve pain after herniation
This Phase 3 study tests whether applying a healing material called platelet-rich fibrin (PRF) around the nerve during disc herniation surgery can reduce leftover nerve pain afterward. If you qualify, your team will compare pain intensity between standard care and PRF during the operation.
Strasbourg, Bas-RhinAges 18 years+ - NCT07304076Recruiting
JHG002 Injection for Chronic Low Back Pain
This study tests if JHG002 injections (made from human placenta) are safe and effective for treating chronic low back pain. It may help people who have had low back pain for at least 6 months and rate their pain as a 5 or higher on a 0–10 scale.
Seoul, Gangdong-guAges 19–70 - NCT05644171Recruiting
Epidural spinal stimulation for chronic spinal cord injury recovery
This trial tests whether a stimulating device placed near the spinal cord can help improve movement and rehabilitative function in people with long-term spinal cord injuries. It may help some patients strengthen function, but only if they meet specific injury and health requirements.
SingaporeAges 21 years+ - NCT05832918Recruiting
Core exercises plus brain tasks for chronic low back pain
This study tests whether doing core (stability) exercises along with simple cognitive (thinking) tasks can reduce long-lasting low back pain. It may help if your pain has lasted at least 3 months and you can safely take part in exercise.
Tehran, Iran (the Islamic Republic Of)Ages 18–55 - NCT05811312Recruiting
Spinal cord stimulation and brain changes in chronic pain
This study uses non-invasive brain monitoring to see how spinal cord stimulation may change brain activity in people with chronic nerve pain. It aims to better understand how treatment affects the brain and pain over time.
Cleveland, OhioAges 18 years+ - NCT06019949Recruiting
Spinal cord stimulation to improve breathing after spinal cord injury
This trial is testing if a device that sends mild electrical pulses to the spinal cord (spinal cord stimulation) can help improve breathing in people with chronic spinal cord injury. It may be a good option if your injury is above the T5 level and you have reduced lung function.
Louisville, KentuckyAges 18 years+ - NCT07559890Recruiting
Nerve ablation for low back pain with Modic changes
This study tests a procedure that uses heat to stop a nerve in the lower back from sending pain signals. It may help people with long-term central low back pain who have not gotten better with other treatments and have Modic changes on MRI.
PragueAges 18 years+ - NCT05605639RecruitingPhase 4
Study tests a targeted injection for neck pain
This trial studies whether an injection near the phrenic nerve can help people with neck pain. It is only for certain types of neck/diaphragm-related problems and excludes people with nerve, injury, cancer, infection, or autoimmune causes.
Dos Hermanas, SevilleAges 18–64 - NCT06491121Recruiting
Can high-intensity training with a smartphone help chronic back pain?
This trial tests if a technology-supported high-intensity exercise program can help adults with chronic low back pain. You'll use your own smartphone to help guide the training and attend regular therapy sessions.
Wilrijk, AntwerpenAges 18–65 - NCT07636967Recruiting
Ankle Muscle Strength in Chronic Low Back Pain
This study measures the strength and function of ankle muscles in people with chronic low back pain lasting over 3 months. Understanding how ankle muscles work may help explain why some people develop long-term low back pain.
Tanta, Gharbia GovernorateAges 20–25 - NCT07551323Recruiting
Myofascial Release vs. Pilates for Chronic Low Back Pain
This study compares two hands-on treatment approaches—myofascial release (deep tissue massage) and Pilates exercises—to see which works better for chronic low back pain that isn't caused by nerve damage. If you have persistent lower-back pain, this trial might help you find relief through one of these therapies.
Istanbul, IstanbulAges 18–45 - NCT07244913Recruiting
Tools for chronic low back pain relief
This trial compares two types of handheld tools—one with metal instruments and one that uses sound waves—to see which works better for long-term low back pain. It may help if you have had pain for at least 6 months and feel tightness in your hamstrings.
Lahore, Punjab ProvinceAges 40–55 - NCT07724704Recruiting
Exercise comparison for long-term low back pain
This study compares two sets of exercises (called McGill and Sahrmann) to see which is better at reducing chronic low back pain. If you have had non-specific low back pain for more than 12 weeks, this trial may help you strengthen your core and feel better without surgery or medication.
Lahore, Punjab ProvinceAges 20–50 - NCT07494162Recruiting
Acupuncture for chronic low back pain with muscle knots
This trial tests if acupuncture can help chronic low back pain by looking at changes in muscle metabolism and blood flow. It compares real acupuncture with a sham (fake) procedure to see if there is a true benefit.
Sacramento, CaliforniaAges 18 years+ - NCT05868668Recruiting
Low-intensity shockwave versus wave therapy for erectile and pelvic pain
This trial compares two types of low-intensity wave therapy to see which works better for erectile dysfunction and/or chronic pelvic pain. Participants may benefit if these therapies improve erection quality and reduce pelvic pain.
Cleveland, OhioAges 40 years+ - NCT05068011Recruiting
Tested spinal cord stimulation for long-term severe back pain
This trial studies a targeted spinal cord stimulation therapy to reduce severe, long-lasting pain. It may help people whose pain is due to failed back surgery and who can safely use the implanted system.
Jette, Brussels CapitalAges 18 years+ - NCT07048366Recruiting
Mindfulness in a museum for fibromyalgia pain relief
This study tests whether a mindfulness program held in a museum setting can help women with fibromyalgia feel less pain and improve their quality of life. You would attend sessions in a museum and practice mindfulness techniques.
Chieti, AbruzzoAges 18–60 - NCT07222462Recruiting
Radiofrequency ablation for chronic low back pain
This study tests if radiofrequency ablation, a procedure that uses heat to block pain signals from the facet joints in your spine, can help people with long-term low back pain that hasn't improved with other treatments like physical therapy.
Atlanta, GeorgiaAges 18 years+ - NCT06619418Recruiting
Home Device Using Sound and Body Stimulation for Back Pain
This study is testing a take-home device that uses sound and gentle body stimulation to help with long-term back pain. It is for adults with chronic low back pain who live near the University of Minnesota and are not taking certain sleep or anxiety medications.
Minneapolis, MinnesotaAges 18 years+ - NCT07193212Recruiting
Osteopathic treatment for low back pain and leg health
This study tests whether a hands-on osteopathic treatment can improve how your legs and feet work if you have chronic low back pain. It may help you understand if this type of manual therapy is a good option for your pain.
Auburn, AlabamaAges 18–65 - NCT05669027Recruiting
Mobile brain training to help low back pain
This study tests whether mobile “neurofeedback” training can reduce low back pain and improve how much it affects your daily life. You would likely use sensors that measure brain and body signals to guide the training.
Durham, North CarolinaAges 18–90 - NCT07326696Recruiting
Therapy for long-term neck pain with limited movement
This trial tests a combination of hand-on treatments (a quick push to the upper back and gentle movements to the neck) to see if it helps people with ongoing neck pain and stiffness. It might be an option if you've had neck pain for more than 3 months and have trouble moving your neck or upper back.
Islamabad, Punjab ProvinceAges 20–40 - NCT07296653RecruitingEarly Phase 1
Prolotherapy for chronic low back pain
This trial tests a treatment called prolotherapy, which uses injections of a sugar solution into specific acupuncture points to help relieve chronic low back pain. It is for people who have had low back pain for at least 3 months, have not had previous back surgery, and have not received similar injections recently.
Athens, AtticaAges 35 years+ - NCT06878014RecruitingPhase 4
Morphine for pain relief after hip replacement surgery
This trial tests different doses of morphine given during spinal anesthesia to find the safest and most effective way to control pain after hip replacement surgery. If you are having a total hip replacement, you may be able to join.
Sosnowiec, Silesian VoivodeshipAges 18–75
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Common questions
- Are there clinical trials for chronic spinal pain?
- Yes. Clin2 currently lists 253 recruiting chronic spinal pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic spinal pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic spinal pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.