Clinical Trials clinical trials

Virtual health educator for cancer trial referrals

This study tests a virtual community health educator to help cancer patients and their caregivers learn more about and join clinical trials. If you have had cancer or care for someone who has, this program might help you find trials that fit.

Well-being education program for teens with heart disease

This study tests whether a special education program about managing emotions and stress helps teenagers with moderate-to-severe congenital heart disease (a heart condition from birth) feel better and cope with their condition. Participants attend sessions and complete surveys over time.

Spanish-language cancer care support for breast or prostate radiation

This study tests an educational and communication support program to help Spanish-speaking people stay on track with treatment when they’re getting radiation for non-spread (non-metastatic) breast or prostate cancer. It may help by improving understanding through interpreter-supported visits.

Comparing tooth graft vs. bone graft for gum disease bone defects

This trial tests whether a graft made from your own extracted tooth works as well as a traditional bone graft, both combined with a special enamel protein, to repair bone loss from gum disease.

Comparing two exercise programs for lowering blood pressure

This study compares two types of exercise programs (short bursts of high-intensity exercise vs. moderate continuous exercise) to see which one lowers blood pressure better in people with hypertension. You may qualify if you have high blood pressure and are between 30 and 59 years old.

Adding chemotherapy when first treatment response is limited

This trial tests whether adding a chemotherapy drug (docetaxel) to your current treatment (apalutamide) can help control prostate cancer that has spread and hasn't responded as well as hoped to apalutamide alone.

Adding chemo to hormone therapy for advanced prostate cancer

This trial is for men with metastatic prostate cancer that has already spread beyond the pelvis. It tests whether adding a chemotherapy drug (docetaxel) to the usual hormone therapy plus apalutamide can help control the cancer better than hormone therapy alone.

Combination therapy for EGFR-mutated lung cancer with lingering ctDNA

This trial tests if adding sacituzumab tirumotecan to osimertinib works better than osimertinib alone for advanced lung cancer that still shows cancer DNA (ctDNA) in the blood after initial osimertinib treatment.

Testing different schedules of a targeted radiation drug for advanced prostate cancer

This trial tests two different dosing schedules of a drug called Lutetium-177 PSMA RLT, which delivers radiation directly to prostate cancer cells. It is for men with advanced prostate cancer that has stopped responding to hormone therapy and has spread, who have not yet had chemotherapy for this stage of the disease.

Dental device secured with bone cement for missing teeth

This trial tests a special dental device that is cemented into the jawbone for people missing one or more teeth. It may be a good option if your jawbone is dense enough and you don't have serious other health issues.

Testing new drug combo for bladder cancer before surgery

This trial tests a combination of two drugs (Tislelizumab and Palbociclib) given before bladder removal surgery. It is for people with bladder cancer that has a specific genetic change and who cannot take the standard chemotherapy cisplatin.

Matching targeted treatments to your prostate cancer's genetics

This trial is testing whether matching your cancer's specific genetic changes to a targeted treatment can help control metastatic prostate cancer that has stopped responding to standard hormone therapy and chemotherapy. You may receive a drug, a radioactive treatment, or a combination based on your tumor's molecular profile.

Positive Peers Intervention Clinical Trial

Study of an experimental injection for chronic hepatitis b

Doctors are testing a new injectable treatment for chronic hepatitis B. This first-in-human study checks the drug's safety and how well it works in people who are already on standard hepatitis B pills.

New drug for advanced esophageal cancer after other treatments

This trial tests a new drug called Ifinatamab Deruxtecan for people with advanced esophageal squamous cell carcinoma that has progressed after one or two prior treatments. It aims to see if the drug can shrink tumors or slow the disease.

Urolithin A for blood sugar in adults 55+ with extra weight

This study tests if a natural supplement called Urolithin A can help improve how your body handles sugar (glucose) in healthy adults aged 55 and older who have a higher body weight. You would take a daily capsule and come in for tests including blood work, treadmill walks, and an MRI.

Antibiotic-coated nail to help prevent infection

This trial studies a special nail for certain broken shin bones to lower the chance of infection after surgery. If you qualify, the study team will help you receive the antibiotic-coated nail and will follow you closely for about a year.

HRS-9821 inhalation treatment for moderate to severe COPD

This trial tests whether an inhaled medication called HRS-9821 can help people with moderate to severe COPD (chronic obstructive pulmonary disease) breathe better and reduce symptoms. You inhale the medication, and researchers will measure how well your lungs work and how you feel over time.

Calderasib and Durvalumab for Advanced Lung Cancer After Chemotherapy

This trial tests a combination of two drugs—calderasib (a targeted therapy) and durvalumab (an immunotherapy)—for people with a specific type of advanced lung cancer that has a KRAS G12C mutation. The goal is to prevent the cancer from coming back after standard chemotherapy and radiation treatment.

Adjuvant vaccine plus immunotherapy for high-risk early lung cancer

This trial tests whether giving a personalized cancer vaccine (Intismeran) with or without an immunotherapy drug (pembrolizumab) after lung cancer surgery can help prevent the cancer from coming back in patients with early-stage, high-risk non-small cell lung cancer.

Digital measures for Huntington's disease trials

This study uses smartphone and wearable sensors to track movement and thinking in people with Huntington's disease. It aims to find better ways to measure how the disease progresses in clinical trials.

Testing MK-7262 and Enlicitide for High Lipoprotein(a)

This trial tests two experimental drugs designed to lower lipoprotein(a)—a type of cholesterol particle linked to heart disease—in people whose levels remain high despite taking statins (cholesterol-lowering medications). The goal is to see if these drugs can safely reduce this risk factor.

Weekly injection study for children with achondroplasia

This trial looks at how safe and effective weekly under-the-skin (subcutaneous) TransCon CNP is for children and teens with achondroplasia over the long term. You may be considered if your child has already finished a previous TransCon CNP study and can follow weekly injection and follow-up visits.

Gut bacteria treatment for fatty liver disease

This study tests whether a specially designed gut bacteria treatment can help people with fatty liver disease and related health issues like high blood sugar, high cholesterol, or high blood pressure. It aims to see if the treatment is safe and improves liver health.