Clinical trials
Cognitive Aging clinical trials
Below are recruiting cognitive aging clinical trials, each written for real people, not researchers. We’re tracking 162 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07048340Recruiting
Therapy for insomnia in kids aged 7-11
This trial tests if a type of talk therapy (cognitive-behavioral therapy) can help children ages 7 to 11 who have trouble sleeping. It aims to improve their sleep without using medicine.
Tel Aviv, IsraelAges 7–11 - NCT06918704Recruiting
Digital brain health program for older adults
This study tests a digital program designed to help support thinking and memory in older adults. It may be a good fit if you are 60+ and generally healthy, even if you have some mild memory concerns.
San Francisco, CaliforniaAges 60–85 - NCT07757529Recruiting
Sage extract for thinking and memory in middle-aged adults
This study tests whether a daily sage extract supplement can improve thinking, focus, and memory in healthy middle-aged adults. If it works, it could offer a natural way to support brain health.
College Station, TexasAges 40–60 - NCT07298876Enrolling by invitation
Ultrasound for memory and sleep in early Alzheimer's
This study tests if a gentle ultrasound treatment to the brain can help improve memory and sleep quality in people with very early Alzheimer's disease. If you have mild memory issues and trouble sleeping, this low-intensity approach might be a safe option to explore.
Hong Kong, Tai Po DistrictAges 60–85 - NCT05372172Recruiting
Tennessee Alzheimer’s study for people 60 and older
This study is looking at how brain and memory changes show up in people across the Alzheimer’s spectrum—from normal thinking to mild memory problems to Alzheimer’s disease. You might join if you can do study visits and an MRI and have a reliable study partner available.
Nashville, TennesseeAges 60 years+ - NCT03372317Recruiting
Tau brain PET imaging study for adults ages 55–90
This study uses a brain scan called PET to look at tau (a brain protein) and how it relates to thinking and memory. It may help researchers understand early brain changes, though it’s mainly for healthy people living near Columbia who have had an amyloid PET scan before.
New York, New YorkAges 55–90 - NCT07156708Recruiting
Aquatic exercise with brain games for older women
This trial tests if doing exercise in water combined with mental tasks can improve health for physically inactive older women. It may help you stay active and sharp.
Pelotas, Rio Grande do SulAges 60–75 - NCT04970888Recruiting
Exercise program to improve thinking and brain blood flow in heart failure
This trial tests whether doing a combined mental (cognitive) and physical exercise program can improve thinking and how well blood flows to the brain in people with chronic heart failure. It may help by strengthening both brain function and physical capacity while your heart condition stays stable.
Montreal, QuebecAges 50 years+ - NCT07315724Recruiting
Block training for brain and hand health in older adults
This trial tests whether a technology-assisted block training program can improve thinking skills, hand coordination, and grip strength in older adults living in the community. It may help keep your mind and hands active as you age.
Yilan, TaiwanAges 65 years+ - NCT05752500Recruiting
Behavior coaching to help older adults with HIV move more
This study tests a tailored behavioral coaching program to increase physical activity in adults age 50+ who have HIV and are currently not very active. It may help you build safer, more routine movement using a Fitbit for tracking.
Minneapolis, MinnesotaAges 50 years+ - NCT07593677Recruiting
Text Messages to Help You Move More
This study tests whether personalized text messages can motivate adults to exercise more. You'll receive encouraging texts over 6 months and track your activity to see if texting helps you stay active.
Ann Arbor, MichiganAges 40 years+ - NCT06989619Recruiting
Sleep and mindfulness program for older adults in residential housing
This study uses peer support and group activities to help older adults living in residential facilities improve their sleep and practice mindfulness (a type of focused relaxation). If you're 55+ and live in a residential building, you may be able to join.
Boston, MassachusettsAges 55 years+ - NCT06027554RecruitingPhase 2
MitoQ for frailty, walking, memory, and blood flow in older adults
This trial tests whether a supplement called MitoQ can improve blood vessel health, walking speed, and thinking skills in older adults who are frail or have mild memory problems. It aims to see if MitoQ helps maintain independence and quality of life.
Farmington, ConnecticutAges 65–80 - NCT06349213Recruiting
Understanding how our brain experiences time
This study uses brain scans and simple tasks to explore how young and older adults perceive time. It aims to uncover the mental and brain processes behind our sense of time.
CaenAges 20–85 - NCT04360200Recruiting
Study of thinking changes in older adults
This trial looks at people over age 50 who have mild thinking or memory problems but do not have dementia by standard clinical criteria. It tests how these early changes are characterized and measured using exams such as blood tests and brain scans, which may help improve understanding and future care.
Guangzhou, GuangdongAges 50 years+ - NCT07610109Recruiting
Community Support Programs for Brain Health in Older Adults
This study tests whether community activities and support programs help older adults keep their thinking skills sharp and improve their quality of life. You would attend programs at a life center and complete some simple assessments.
Istanbul, BagcılarAges 60 years+ - NCT07085663Recruiting
Exergame brain and body training for adults 50-60 in China
This study tests whether combining exercise video games with memory and thinking tasks can help middle-aged adults who feel their memory is getting worse. It aims to see if this type of training can improve both physical and mental function.
Chengdu, SichuanAges 50–60 - NCT04962061Recruiting
Multidomain program to help prevent memory decline
This trial tests a combined lifestyle/health program to help prevent thinking and memory problems in older adults with cardiovascular risk factors. It may help by improving activity, health habits, and overall brain health over time.
Montreal, QuebecAges 60 years+ - NCT05725668Recruiting
Dual-task exercise to help prevent falls in memory trouble
This study tests a type of exercise training (doing a physical task while also doing a thinking task) to help older adults with mild memory problems prevent falls. If you have fallen before or have trouble with balance, this program may help you improve safety and coordination.
Springfield, OregonAges 65–95 - NCT07667985Recruiting
Cognitive Reserve and Recovery from Fatigue in Older Adults
This study looks at how life experiences and education (cognitive reserve) help older adults bounce back from mental fatigue. Researchers want to find out if higher cognitive reserve leads to faster recovery after tiredness, which could improve quality of life.
Uşak, UşakAges 65–90 - NCT06927362Recruiting
Exercise and balance training for seniors with memory issues
This study tests if combining two types of exercise (LSVT Big and dual-task training) can improve balance and thinking in older adults with mild to moderate memory loss. It may help you stay steady on your feet and manage everyday tasks more easily.
Lahore, Punjab ProvinceAges 65 years+ - NCT05655325Recruiting
Exercise program to improve thinking in older adults with mild memory trouble
This study tests whether a supervised exercise plan can improve executive thinking (like planning and task control) in older adults with mild cognitive impairment. Researchers also look for brain changes using an MRI.
New York, New YorkAges 55 years+ - NCT06816797Recruiting
Testing a program for older adults worried about memory
This trial tests a program called Cog-Fun Aging to help older adults who notice memory changes and feel concerned. The study looks at whether the program can improve daily function and well-being.
JerusalemAges 60 years+ - NCT05460468Recruiting
Brain stimulation study to improve memory in aging
This study tests a brain-stimulation approach to help improve memory as people age. You may be able to take part if you can consent and meet safety and medical criteria, especially related to brain/nerve health and seizure risk.
Durham, North CarolinaAges 18–75
Hear when a new Cognitive Aging trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for cognitive aging?
- Yes. Clin2 currently lists 162 recruiting cognitive aging studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognitive aging trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognitive aging trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.