Clinical trials
Cognitive Change clinical trials
Below are recruiting cognitive change clinical trials, each written for real people, not researchers. We’re tracking 82 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06709027Enrolling by invitation
Mobile health program for depression in older adults
This study is testing a smartphone-based health program designed for older adults with depression. The program aims to help you manage your mood and track changes in thinking and memory using a mobile app.
Fuzhou, FujianAges 60 years+ - NCT06378515Recruiting
Physical activity, sleep, and brain health in students
This study looks at how physical activity and sleep affect your brain health, especially the glymphatic system — a system that helps clear waste from your brain. It is for university students and could help you understand how your daily habits influence your brain.
ValenciaAges 18–40 - NCT06904508Recruiting
Therapy for anxiety in autistic youth from high-need communities
This trial tests whether cognitive behavioral therapy (CBT) can help reduce anxiety in autistic children and teens. It also looks at brain activity changes before and after therapy.
Montclair, New JerseyAges 8–14 - NCT07485816Enrolling by invitation
Heart-brain oxygen and thinking changes in heart failure
This study looks at how well your heart and brain work together to use oxygen, and how that relates to changes in thinking and memory for people with heart failure.
Kunming, YunnanAges 18–70 - NCT06105307Enrolling by invitation
Improving sleep and fatigue for night shift RNs
This trial uses mobile technology and cognitive-behavioral techniques to help night shift nurses improve their sleep and reduce fatigue. If you work night shifts and have a smartphone, you may be eligible to join.
Cincinnati, OhioAges 18 years+ - NCT06127511Recruiting
Peanut study for brain health and weight in teens
This trial tests whether eating peanuts every day helps thinking, learning, and memory and manages weight and inflammation in young teens.
Barcelona, BarcelonaAges 10–12 - NCT04107285Recruiting
Study brain changes in people with lymphoma after CAR T
This study looks at how thinking and brain function change over time in people with lymphoma who receive CAR T therapy. It may help doctors understand side effects and better support patients during and after treatment.
New York, New YorkAges 18 years+ - NCT07593677Recruiting
Text Messages to Help You Move More
This study tests whether personalized text messages can motivate adults to exercise more. You'll receive encouraging texts over 6 months and track your activity to see if texting helps you stay active.
Ann Arbor, MichiganAges 40 years+ - NCT06600100Recruiting
Inhibitory control training for weight management
This trial tests an online training program designed to improve your ability to resist cravings and make healthier choices. It may help you lose weight by strengthening the part of your brain that controls impulses.
GranadaAges 18–60 - NCT05917262Recruiting
Mindfulness breathing vs heart-rate training after shoulder surgery pain
This trial compares two non-drug techniques—mindful breathing and heart-rate (HR) biofeedback—to see which helps reduce pain after shoulder surgery. You may be able to join if you have ongoing shoulder pain after surgery and haven’t been using these practices very often.
TaoyuanAges 18 years+ - NCT06005363Recruiting
Brain fluid study in shunt surgery patients
This study looks at brain fluid and drainage function in patients receiving a VP shunt for hydrocephalus. It may help understand how the brain clears waste products.
TaoyuanAges 60 years+ - NCT05194930Recruiting
Insomnia treatment study for Veterans with PTSD symptoms
This study tests treatments to help Veterans who have both PTSD symptoms and trouble sleeping (insomnia). You may be invited to try study procedures to see what helps insomnia and whether it also improves sleep-related well-being.
Sepulveda, CaliforniaAges 18 years+ - NCT07168824Enrolling by invitation
Can a probiotic improve memory in adults with mild cognitive decline?
This trial tests whether a daily probiotic called Lacticaseibacillus paracasei PS23 can help improve thinking and memory in adults aged 50 to 85 who feel their memory is slipping but do not have dementia or Alzheimer's disease.
TaoyuanAges 50–85 - NCT07021053Recruiting
Online therapy for alcohol use: a Canadian study
This trial tests an internet-delivered cognitive behaviour therapy program for people who drink more than they'd like. It aims to see how your daily actions and decisions affect your drinking habits and help you make changes.
Regina, SaskatchewanAges 18 years+ - NCT07511270Recruiting
Predicting thinking skills from speech using AI
This study uses an AI tool to analyze short stories you tell aloud, to see if it can predict your thinking and memory test scores. It may help develop a simpler way to check cognitive health.
TaoyuanAges 50 years+ - NCT06835556Recruiting
Studying paranoia changes with talk therapy
This trial tests how a type of talk therapy affects paranoia in people with schizophrenia or related conditions. It aims to understand if daily changes in paranoia can improve with treatment.
Nashville, TennesseeAges 18–65 - NCT06286774Recruiting
Sleep and alcohol treatment study
This study tests whether improving sleep through cognitive behavioral therapy (CBT-I) can help reduce heavy drinking in people with both alcohol use disorder and insomnia. It might be a good fit if you have trouble sleeping and drink heavily.
Columbia, MissouriAges 18–49 - NCT06467539RecruitingPhase 2
New combination treatment for early Alzheimer's or memory loss
This trial tests a new combination treatment (DAOIB and an antioxidant) for people with early Alzheimer's or mild cognitive impairment. It aims to see if the treatment can help slow or improve memory and thinking problems.
Kaohsiung CityAges 50–90 - NCT06392945Recruiting
Walking and thinking training with music for chronic stroke recovery
This trial tests whether adding a rhythmic beat (like a metronome or music) to walking while doing thinking tasks can improve walking after a stroke. It is for people who had a stroke more than 6 months ago and can already walk a short distance.
TaipeiAges 20–85 - NCT04106713Recruiting
Understanding change across different psychotherapies for anxiety and depression
This study looks at how people change during different types of psychotherapy for anxiety and depression. It aims to understand which treatments work best for different people.
Singapore, SingaporeAges 18–99 - NCT07293494Recruiting
Spaceflight stress and brain changes study
This study looks at how the stress of spaceflight affects the brain and behavior. You will complete tasks and have MRI scans while staying in a controlled environment, including some sleep disruption and alcohol consumption.
Philadelphia, PennsylvaniaAges 21–60 - NCT07740967Recruiting
Collagen and omega supplements for middle-aged women
This study tests whether daily collagen and omega-3 supplements can improve health in healthy middle-aged women. You would take the supplements for a period and have your health measured.
LoughboroughAges 35–65 - NCT06715995Recruiting
Light stimulation's effect on brain waves in healthy older adults
This trial tests if a special light (gamma light) can change brain wave patterns in healthy adults over 55. It aims to understand how light might help keep the brain sharp.
Taoyuan, GuishanAges 55 years+ - NCT07729930Recruiting
Creatine supplement study for healthy middle-aged women
This study is testing a creatine supplement (a substance that may help with energy and muscle function) in healthy middle-aged women. You may join if you are between 35 and 65, a non-smoker, and have a certain activity level.
LoughboroughAges 35–65
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Common questions
- Are there clinical trials for cognitive change?
- Yes. Clin2 currently lists 82 recruiting cognitive change studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognitive change trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognitive change trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.