Clinical trials
Cognitive Change clinical trials
Below are recruiting cognitive change clinical trials, each written for real people, not researchers. We’re tracking 73 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06112964Recruiting
Brain and behavior changes in cancer-related weight loss
This study looks at changes in thinking, behavior, and brain structure that can happen when people with cancer lose weight and appetite (called cachexia). Researchers will use questionnaires and brain scans to understand these changes, which may help improve care for people with cancer.
CambridgeAges 18 years+ - NCT06534684Recruiting
Brain stimulation (iTBS) for depression and thinking changes
This study tests whether a type of brain stimulation called iTBS can improve depression and thinking skills. It uses a magnetic coil over the scalp and is done on multiple days.
TromsøAges 22–65 - NCT06605898Recruiting
Metabolic and lifestyle study for adults 45-64
This study tests a personalized diet and lifestyle program to improve metabolic health. It may help if you are between 45 and 64, do not smoke, and have no major digestive or liver conditions.
Urbana, IllinoisAges 45–64 - NCT06721468Recruiting
Trout eating and brain health in kids and families
This study looks at how eating trout may affect brain health in children and their families. It has three parts for different age groups, and you may be asked to eat trout or answer questions online.
Moscow, IdahoAges 3 years+ - NCT04861818Recruiting
Testing how exercise timing affects memory in healthy young adults
This study looks at whether the time of day you exercise changes how well you remember things. It asks healthy young adults to do controlled exercise over two lab visits and avoids exercise for a few days to compare results.
Greensboro, North CarolinaAges 18–25 - NCT07432425Recruiting
Exercise programs for chronic neck pain
This study compares different exercise programs to see which one improves physical and mental health in people with chronic neck pain. You may be eligible if you have had neck pain for at least 3 months and it is moderate to severe, but you haven't been in a recent neck pain rehab or exercise program.
Ankara, AltindagAges 20–65 - NCT07383324Recruiting
Heat stress study for people with schizophrenia
This study looks at how people with and without schizophrenia respond to heat stress. It aims to understand how heat affects the body, which may help improve safety and care during hot weather.
Ottawa, OntarioAges 18–85 - NCT07271927Recruiting
Light therapy for Parkinson's motor and thinking changes
This study tests whether shining light on the whole body (photobiomodulation) can help with movement and thinking problems in Parkinson's disease. It is for people in early to moderate stages who can walk independently.
Yangsan, Gyeongsangnam-doAges 40 years+ - NCT07261202Recruiting
Heat's effect on children's bodies in hot homes
This study looks at how hot indoor temperatures affect children's physical responses. It may help families understand how to keep kids safe during heat waves.
Ottawa, OntarioAges 10–15 - NCT07267598Recruiting
Can a 26 °C room help young adults stay cool?
This study tests whether keeping a room at 26 °C (about 79 °F) helps healthy young adults stay cool without discomfort. It's for people who are not smokers, not highly trained athletes, and not pregnant.
Ottawa, OntarioAges 18–29 - NCT07147894Recruiting
Executive Function Training for Teens and Kids
This study tests a new type of training designed to help children and teens improve their executive function skills—things like planning, focus, and self-control. It is open to kids ages 12 to 17, especially those with ADHD, as long as they are not currently taking ADHD medication and have a parent who can join the training.
Boston, MassachusettsAges 12–17 - NCT07011602Recruiting
Child Activity and Nutrition Study
This study helps kids ages 6-11 who face economic or educational challenges build healthier habits. It combines physical activity and nutrition guidance to support overall well-being.
Bloomington, IllinoisAges 6–11 - NCT05894967Recruiting
Study on how perceptual learning works in different age groups
This study looks at what helps people improve how they perceive visual information (“perceptual learning”) and what processes are responsible. It includes younger and older adults and mainly needs good vision and no known eye or brain conditions affecting the retina or nerves.
Riverside, CaliforniaAges 18–85 - NCT05699226Recruiting
Testing whether adjusting ECT treatment helps depression outcomes
This study tests a way of adjusting (titrating) ECT treatment to improve outcomes in people with major depression or bipolar II. It’s mainly for those who already need ECT with right-side electrode placement.
Albuquerque, New MexicoAges 50 years+ - NCT05597124RecruitingPhase 2
Exercise program to improve brain health in older Black adults
This Phase 2 study tests whether a structured exercise program can improve brain health in adults age 60 and older who are less active and have early thinking/memory concerns. It may help maintain or improve thinking abilities over time, with medical supervision throughout the study.
Newark, New JerseyAges 60 years+ - NCT05457725Recruiting
Study how aging affects learning to trust and distrust
This study looks at how thinking and learning processes change with age, especially around deciding what to trust. You may be asked to complete computer tasks and brief memory/thinking tests to understand these changes.
Gainesville, FloridaAges 18–100 - NCT06951919Recruiting
HOBSCOTCH study for memory help in MS
This trial tests a program called HOBSCOTCH to help people with MS who have memory or thinking problems. It also includes a caregiver who supports them.
Lebanon, New HampshireAges 20–75 - NCT05976152RecruitingPhase 3
Butyphthalide to improve thinking after a recent stroke
This Phase 3 study tests whether butyphthalide can help thinking and memory improve after an acute ischemic stroke. It compares people who take the study medicine versus usual care, and measures cognitive (thinking) changes over follow-up.
Dandong, LiaoningAges 60 years+ - NCT05694039Recruiting
Track thinking changes in older adults with hearing loss
This study follows older adults who have age-related hearing loss to see whether wearing hearing aids helps protect thinking and memory over time. You may be included if your hearing loss is the type that hearing aids can usually improve and if your thinking test scores suggest mild cognitive difficulties.
Guangzhou, GuangdongAges 60–85 - NCT06930846Recruiting
Brain cancer cognitive training study
This study tests a home-based program called HOBSCOTCH-CA to help with memory and thinking problems after brain cancer treatment. The program uses phone and internet sessions to teach self-management skills.
Lebanon, New HampshireAges 18 years+ - NCT07485816Enrolling by invitation
Heart-brain oxygen and thinking changes in heart failure
This study looks at how well your heart and brain work together to use oxygen, and how that relates to changes in thinking and memory for people with heart failure.
Kunming, YunnanAges 18–70 - NCT06904508Recruiting
Therapy for anxiety in autistic youth from high-need communities
This trial tests whether cognitive behavioral therapy (CBT) can help reduce anxiety in autistic children and teens. It also looks at brain activity changes before and after therapy.
Montclair, New JerseyAges 8–14 - NCT06709027Enrolling by invitation
Mobile health program for depression in older adults
This study is testing a smartphone-based health program designed for older adults with depression. The program aims to help you manage your mood and track changes in thinking and memory using a mobile app.
Fuzhou, FujianAges 60 years+ - NCT06105307Enrolling by invitation
Improving sleep and fatigue for night shift RNs
This trial uses mobile technology and cognitive-behavioral techniques to help night shift nurses improve their sleep and reduce fatigue. If you work night shifts and have a smartphone, you may be eligible to join.
Cincinnati, OhioAges 18 years+
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Common questions
- Are there clinical trials for cognitive change?
- Yes. Clin2 currently lists 73 recruiting cognitive change studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognitive change trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognitive change trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.