Clinical trials
Cognitive Dysfunction, Cognitive Disorder clinical trials
Below are recruiting cognitive dysfunction, cognitive disorder clinical trials, each written for real people, not researchers. We’re tracking 124 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05877885Recruiting
Digital treatment for low motivation in older adults with depression
This study tests a digital therapy to improve apathy (feeling unmotivated or “checked out”) in people age 60+ who have depression. It also uses brain imaging (MRI) and questionnaires to see whether the treatment helps brain function linked to motivation.
Orlando, FloridaAges 60 years+ - NCT07657624Recruiting
Heart disease and memory problems risk study
This study looks at what factors might increase the risk of memory and thinking problems in people with coronary heart disease. It includes testing your memory and metabolism during a hospital stay.
Beijing, ChinaAges 18 years+ - NCT07128186Recruiting
AI predicts memory decline in type 2 diabetes
This study uses an AI tool to predict memory problems in people with type 2 diabetes. It may help catch early signs of cognitive decline and guide future care.
Enshi, HubeiAges 40–75 - NCT05356611Recruiting
Study for depression and mild memory thinking problems
This trial tests a program aimed at helping older adults with depression who also have mild thinking and memory difficulties. You may be asked to complete study sessions and tracking, with support for depression symptoms and thinking function.
Las Vegas, NevadaAges 60 years+ - NCT04109027Recruiting
Training program to improve thinking and memory for veterans
This trial tests an intensive skills-training program to help with thinking and memory problems after a mild-to-moderate traumatic brain injury (TBI). It’s designed for veterans who are at least 6 months past the injury and still notice cognitive symptoms that affect daily goals like work or school.
Sacramento, CaliforniaAges 21–60 - NCT05830942Recruiting
Training walks plus brain stimulation for thinking skills in older adults
This study tests whether a structured walking exercise, combined with brain stimulation and brain scans, can improve or slow decline in thinking skills. It’s aimed at older adults who notice memory or confusion getting worse.
Gainesville, FloridaAges 65 years+ - NCT06799481Recruiting
Home-based exercise to help brain tumor survivors with thinking and memory
This study tests whether a virtual home-based exercise program can improve thinking and memory problems caused by brain tumor treatment in teens and young adults. It also looks at how exercise affects gut health.
Atlanta, GeorgiaAges 15–39 - NCT07633626Recruiting
Vortioxetine for thinking problems from ALK lung cancer treatment
This trial tests whether a medication called vortioxetine can help improve memory, focus, and thinking problems caused by lorlatinib, a drug used to treat ALK-positive lung cancer. You would take vortioxetine alongside your current cancer treatment to see if it helps your brain function.
BogotáAges 18 years+ - NCT04816006Recruiting
Breast cancer, thinking, and exercise study
This trial tests whether exercise can help thinking and reasoning in women over 50 who have had early-stage breast cancer. It compares a moderate exercise program with health education sessions.
Phoenix, ArizonaAges 50 years+ - NCT07220512Recruiting
Exercise help for ovarian, fallopian, or endometrial cancer
This trial tests a special exercise program during chemotherapy before surgery. It may help patients with certain gynecologic cancers get stronger and better prepared for treatment.
Winston-Salem, North CarolinaAges 55 years+ - NCT05649800Recruiting
Study brain and blood-vessel changes in older adults after stroke
This study looks at how blood flow in the brain and related brain processes change after stroke, especially when someone also has conditions like dementia, depression, or delirium. It may help researchers understand what drives these problems and how they connect.
Leicester, LeicestershireAges 65 years+ - NCT06021197RecruitingPhase 2
NMDA-enhancing treatment for cognitive symptoms in schizophrenia
This study tests a new treatment that may help with thinking and memory problems in people with schizophrenia. It is for people whose schizophrenia symptoms are stable and who are already on a steady medication.
TaichungAges 18–65 - NCT06042699Recruiting
Iron deficiency and scoliosis study for teens and young adults
This study tests whether giving iron supplements before spinal fusion surgery can help kids with low iron levels. It aims to understand iron deficiency in young people with scoliosis and improve their surgical outcomes.
New York, New YorkAges 10–26 - NCT06419101Recruiting
Finding early signs of memory loss in China
This trial looks for new ways to diagnose memory and thinking problems earlier. It involves a memory test, brain scan, and blood draw to find markers that could help identify cognitive disorders.
BeijingAges 40–90 - NCT06817395Recruiting
Thinking and memory in chronic ITP
This study looks at whether chronic or persistent immune thrombocytopenia (ITP) affects thinking and memory. If you have had low platelet counts for 3 months or more and have been treated for ITP, you may help researchers understand how the condition can impact the brain.
Boston, MassachusettsAges 18 years+ - NCT06572332Enrolling by invitation
Brain scan study for sleep in older Chinese adults
This study uses brain scans to understand sleep problems in older Chinese adults. If you are 60+ and have trouble sleeping, you may help researchers find better ways to improve sleep.
Hong KongAges 50–90 - NCT07560696Recruiting
Web-based therapy for thinking and speech after illness
This study tests whether patients recovering from serious illness in the ICU or stroke ward can use a web-based platform called Cognishine to help rebuild their thinking skills and speech ability. The goal is to see if this online approach works well and is practical for patients receiving support from therapists.
LiverpoolAges 18 years+ - NCT07508215Recruiting
Bright light therapy for memory problems in depression
This study tests whether daily bright light therapy can improve thinking and memory in people with major depression. You would continue your regular antidepressant and add 30-60 minutes of light box use each morning.
Beijing, Beijing MunicipalityAges 18–60 - NCT07298876Enrolling by invitation
Ultrasound for memory and sleep in early Alzheimer's
This study tests if a gentle ultrasound treatment to the brain can help improve memory and sleep quality in people with very early Alzheimer's disease. If you have mild memory issues and trouble sleeping, this low-intensity approach might be a safe option to explore.
Hong Kong, Tai Po DistrictAges 60–85 - NCT05695131Recruiting
Testing virtual reality speech therapy for adults
This study checks whether a virtual reality (VR) version of a speech-language therapy program is practical and works the way it should. You might benefit by getting speech therapy in a new, technology-based format, and helping researchers confirm it is safe and feasible.
Edmonton, AlbertaAges 18 years+ - NCT07106879Recruiting
Pre-screening for future metabolic and psychiatric studies
This study does not test a new treatment. It is a pre-screening program to see if you might qualify for future clinical trials on metabolic conditions (like diabetes or weight issues) or psychiatric health (like depression or anxiety). You will be asked some questions and may do some basic health checks to see which future trials could be a good fit for you.
Brooklyn, New YorkAges 18 years+ - NCT04685746Recruiting
Testing how balance and motion affect child development
This study looks at how the vestibular system (your balance and motion sensing) is involved in children’s thinking and movement. It compares typically developing children with children who have balance-related (vestibular) problems or certain neurodevelopmental conditions to understand what to expect and how development may differ.
GhentAges 6–13 - NCT05661084Recruiting
Non-surgery brain stimulation for dementia thinking and movement
This study tests whether a non-invasive brain stimulation device (tES) can improve thinking and movement problems in people with dementia. You (and your caregiver, if needed) will be asked to follow the study plan and attend visits so researchers can measure results and safety.
Boston, MassachusettsAges 55 years+ - NCT07272213Recruiting
Thyroid hormone levels, mood, and sexual health in pregnancy
This study looks at how thyroid-stimulating hormone (TSH) levels during pregnancy are linked to depression, anxiety, and sexual function in pregnant women.
Istanbul, GaziosmanpaşaAges 18–45
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Common questions
- Are there clinical trials for cognitive dysfunction, cognitive disorder?
- Yes. Clin2 currently lists 124 recruiting cognitive dysfunction, cognitive disorder studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognitive dysfunction, cognitive disorder trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognitive dysfunction, cognitive disorder trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.