Clinical trials
Cognitive Dysfunction, Cognitive Disorder clinical trials
Below are recruiting cognitive dysfunction, cognitive disorder clinical trials, each written for real people, not researchers. We’re tracking 124 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06741566RecruitingEarly Phase 1
Nasal spray before heart bypass to protect memory
This study tests whether a nasal spray containing dexmedetomidine or insulin, given before heart bypass surgery, can help prevent memory and thinking problems that sometimes happen after the operation. It is for adults 60 and older.
Al FayyumAges 60–75 - NCT07413562Recruiting
Nerve stimulation for memory problems after brain injury
This trial tests whether stimulating a nerve in the wrist (median nerve) can help improve thinking and memory problems in people who have had a recent traumatic brain injury. It is for adults with moderate injuries who have trouble with memory and thinking.
Beijing, Beijing MunicipalityAges 18–64 - NCT07637357Recruiting
How anesthesia affects thinking after weight-loss surgery
This study looks at how different types of anesthesia used during sleeve gastrectomy (a weight-loss surgery) may affect your memory and thinking skills after the operation. Researchers want to understand which anesthesia approach is safest for your brain.
Istanbul, SancaktepeAges 18–65 - NCT06793735Recruiting
Virtual reality app for memory and thinking problems
This trial tests a virtual reality app you can use at home to help with early memory or thinking problems. It may be an option if you have mild cognitive impairment or notice your thinking is slowing down.
Messina, ItalyAges 40–80 - NCT06587841Recruiting
Spinal cord stimulation for early spinal cord injury
This study tests a noninvasive spinal cord stimulation device for people with recent or long-term spinal cord injury. It aims to improve bladder function and is conducted in British Columbia, Canada, and Ukraine.
Vancouver, British ColumbiaAges 19–65 - NCT07598552Recruiting
Brain Function Changes After Same-Day Hip or Knee Surgery
This study checks whether patients who have hip or knee replacement surgery and go home the same day experience any temporary changes in thinking or memory. Researchers want to understand how anesthesia and surgery affect the brain in the short term.
SvendborgAges 70 years+ - NCT06095297Recruiting
Cognitive rehab for brain fog from long COVID
This study tests a computer-based cognitive training program combined with a gentle nerve stimulation device to see if it can improve brain fog and daily functioning in people with long COVID. If you're struggling with thinking, memory, or concentration after COVID, this might help.
Birmingham, AlabamaAges 18 years+ - NCT07523113Recruiting
Brain Fog Treatment for ME/CFS Using Cognitive Training
This study tests whether a computerized cognitive training program combined with a mild electrical nerve stimulation device (worn on the ear) can help improve thinking and memory problems in people with ME/CFS. The goal is to see if this approach helps with brain fog and daily functioning.
Birmingham, AlabamaAges 18 years+ - NCT05445180Recruiting
Brain scan study of thinking in cannabis users with psychosis
This study uses brain imaging to understand how thinking works in people who use cannabis, comparing those with psychosis to people without psychosis. It may help researchers learn what brain patterns relate to thinking difficulties and how cannabis use fits in.
Montreal, QuebecAges 16–80 - NCT07727837Recruiting
Pelvic floor health in children with poop problems
This trial looks at how defecation disorders (trouble pooping or soiling) in children affect their quality of life, walking, balance, and physical function. It aims to understand the links between these problems and the pelvic floor muscles.
Izmir, BornovaAges 6–18 - NCT06672367Recruiting
Balance and gaze exercises for brain health in older adults
This study looks at whether adding gaze stability exercises (eye and head movements) to balance training can improve thinking, balance, and walking steadiness in older adults with mild memory problems. It may help those who can follow simple instructions and join in physical activity.
IslamabadAges 55 years+ - NCT07073781Recruiting
Probiotics for Brain & Blood Sugar in Overweight Young Adults
This study tests whether taking a probiotic (a 'good bacteria' supplement) can help brain function (thinking, memory) and improve blood sugar control in overweight adults who have higher-than-normal blood sugar. If you're between 18-40, overweight, and don't have diabetes, you may be able to join.
Leeds, Greater ManchesterAges 18–40 - NCT06186830Recruiting
Questionnaire for jaw and face pain
This study tests a special questionnaire (BETY-BQ) to see how well it measures the impact of jaw and face pain in people with temporomandibular disorders. It helps doctors better understand your symptoms and guide treatment.
Karabük, Karabük ProvinceAges 18–64 - NCT07114809Recruiting
Can brain stimulation and virtual reality boost thinking in MS?
This study tests whether a combination of gentle brain stimulation (tDCS) and virtual reality exercises can improve memory and thinking problems in people with multiple sclerosis. If you have mild to moderate disability and no major health issues, you may be able to join.
Genova, ItalyAges 18–65 - NCT06423547Recruiting
Predicting confusion after surgery in older adults
This study looks at older patients (65 and older) who have had surgery and anesthesia. It aims to find who is at risk for confusion (delirium) and memory problems afterward. The goal is to help doctors prevent these issues.
BeijingAges 65–100 - NCT05667857Recruiting
Tracking brain, mood, and quality of life after immunotherapy
This study follows people who have had advanced cancer and are now stable after immunotherapy, to see how thinking, mood, and daily life change over time. Some participants may also do an integrative brain-training program if they have memory or thinking problems.
Brussels, Brussels CapitalAges 18 years+ - NCT07452367Recruiting
Bentall surgery study: optic nerve and thinking ability
This study checks if swelling of the optic nerve sheath during heart surgery with a bypass machine is linked to changes in thinking ability after the operation. It may help understand why some people have mental fogginess after surgery.
Bursa, YıldırımAges 18–80 - NCT06036095RecruitingPhase 4
Comparing two types of anesthesia in older adults having surgery
This study compares two types of general anesthesia for older adults (70+) having planned non-heart, non-brain surgery that lasts at least 2 hours. The goal is to see which type might be better for preserving thinking and memory after surgery.
Portland, OregonAges 70–110 - NCT07531888Enrolling by invitation
Brain Stimulation to Improve Memory in Older Adults
This study tests whether a non-invasive brain stimulation technique (tDCS) can help improve memory and thinking skills in people aged 60–75 who have noticed mild memory problems. You'll receive either real or sham (placebo) stimulation and undergo cognitive training over several weeks.
Pachuca, HidalgoAges 60–75 - NCT07304843RecruitingPhase 1/Phase 2
Testing golexanolone for fatigue and brain fog in PBC
This study tests an experimental drug called golexanolone to see if it can help with fatigue and thinking problems in people with primary biliary cholangitis (PBC). It involves taking two different doses of the drug and checking how you feel and think over time.
DüsseldorfAges 18 years+ - NCT06136546RecruitingPhase 2
Infliximab for depression with cognitive problems
This trial tests if a medicine called infliximab, given through an IV, can help improve thinking and memory problems in people with moderate to severe depression who also have high inflammation levels. It aims to see if lowering inflammation can ease both mood and cognitive symptoms.
Boston, MassachusettsAges 25–50 - NCT07245186Enrolling by invitation
Healthy living program for kidney decline
This study tests a program to help people with chronic kidney disease (CKD) stay healthy through diet tracking and other proactive steps. It focuses on people whose kidney function has declined but who are not yet on dialysis.
Shanghai, Shanghai MunicipalityAges 18–90 - NCT06932406Recruiting
Personality and self-help for jaw pain
This study tests whether a self-management program for jaw and face pain works differently in people with different personalities. You will learn techniques to manage your pain at home.
Valencia, ValenciaAges 18–65 - NCT07750223Recruiting
Hesperidin for memory and thinking in older adults
This study tests whether a natural supplement called hesperidin (found in citrus fruits) can support brain health in older adults who are overweight or obese. It may help with memory and thinking.
Shanghai, Shanghai MunicipalityAges 55–75
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Common questions
- Are there clinical trials for cognitive dysfunction, cognitive disorder?
- Yes. Clin2 currently lists 124 recruiting cognitive dysfunction, cognitive disorder studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognitive dysfunction, cognitive disorder trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognitive dysfunction, cognitive disorder trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.