Clinical trials
Cognitive clinical trials
Below are recruiting cognitive clinical trials, each written for real people, not researchers. We’re tracking 1,981 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06407141Enrolling by invitation
Brain stimulation study for older adults with mild memory loss
This trial tests whether a harmless brain stimulation technique called TPS can improve memory and thinking in older adults with mild memory problems. You may be able to join if you have MCI, are right-handed, and are generally healthy otherwise.
Hong KongAges 50–100 - NCT06398990Recruiting
Cognitive exercise therapy vs. yoga for teen period pain
This study compares two non-drug treatments—a cognitive exercise therapy approach and yoga—to see which helps reduce pain and improve quality of life in teenagers with period pain. If you are between 10 and 19, have moderate to severe menstrual cramps, and have never given birth, you may be eligible.
Istanbul, AtaşehirAges 10–19 - NCT06376500Recruiting
Brain stimulation to help thinking after concussion
This study tests whether a non-invasive brain stimulation technique called transcranial direct current stimulation (tDCS) can help improve thinking and memory problems that some people have after a mild concussion. tDCS uses a small electrical current from scalp electrodes to gently activate parts of the brain.
Hung Hom, KowloonAges 18–65 - NCT04754906Recruiting
Study how thinking abilities affect planning movement
This study looks at how well people can plan and control movements, and whether thinking ability affects that process. It compares healthy younger adults, healthy older adults, and older adults with mild cognitive problems.
DijonAges 18 years+ - NCT06349213Recruiting
Understanding how our brain experiences time
This study uses brain scans and simple tasks to explore how young and older adults perceive time. It aims to uncover the mental and brain processes behind our sense of time.
CaenAges 20–85 - NCT06338774Recruiting
Can cognitive training boost physical activity in midlife adults?
This study tests whether combining cognitive training with aerobic exercise can help 'low active' adults aged 40–65 become more physically active. Participants will do both brain games and exercise to see if this combo improves adherence.
Iowa City, IowaAges 40–65 - NCT06321588Recruiting
Autoimmune dementia: predicting antibodies in new cognitive decline
This study looks for certain antibodies that might be causing your new memory or thinking problems. It aims to find patterns that could help diagnose autoimmune dementia earlier.
Bologna, BolognaAges 40–90 - NCT06321965Recruiting
Study of SMA in Children on SMN-Boosting Therapies
This study is looking for children and teens with spinal muscular atrophy (SMA) who are already on a treatment like Spinraza, Evrysdi, or Zolgensma. The goal is to understand different forms of SMA and how the treatment affects them over time.
Bron, RhoneAges birth–16 years - NCT06336174Recruiting
Thinking and Memory in Brain Artery Narrowing: A Study
This study looks at how severe narrowing of brain arteries may affect memory and thinking over time. It involves people who have had a mini-stroke or mild stroke and aims to understand the changes in cognitive function.
Hefei, AnhuiAges 18–80 - NCT06303622Recruiting
Comparing two MRI-guided biopsy methods for prostate cancer
This trial compares two ways to guide a prostate biopsy using MRI images, to see which better detects clinically significant prostate cancer in men with suspicious MRI findings.
Hong KongAges 18 years+ - NCT05587127Recruiting
CBT therapy for eating anxiety in functional stomach pain
This trial tests an “exposure-based” type of cognitive behavioral therapy (CBT) to help people with functional dyspepsia (stomach discomfort after eating) who avoid or restrict food. The goal is to reduce food fear and improve eating and weight, after other medical causes have been ruled out.
Boston, MassachusettsAges 18 years+ - NCT06281756RecruitingEarly Phase 1
CBT and Trazodone for Sleep and Blood Pressure in Insomnia
This trial tests whether cognitive behavioral therapy (a type of talk therapy for sleep) and/or the medication trazodone can improve sleep and lower blood pressure in people with chronic insomnia. You must be 18 or older and have ongoing trouble sleeping.
Denver, ColoradoAges 18 years+ - NCT06034509Recruiting
Thinking and blood vessel health after head injury
This study looks at how a past traumatic brain injury (TBI) might affect your thinking skills and blood vessel health over time. You may be eligible if you had a TBI at least 3 years ago and have already completed an earlier evaluation at the National Intrepid Center of Excellence (NICoE).
Bethesda, MarylandAges 18–74 - NCT05895344Recruiting
Compare proton vs modern radiation effects on thinking
This study compares two types of radiation—proton therapy versus modern fractionated radiation—to see how they affect long-term thinking (cognitive function) and daily abilities in people with a specific skull-base tumor. It may help clarify which radiation approach best protects brain and nerve function over time.
CaenAges 18–70 - NCT06262412Recruiting
Online CBT for teens with body dysmorphic disorder
This trial tests an internet-based cognitive-behavioral therapy program for children and teenagers (ages 12-17) with body dysmorphic disorder. It aims to help them manage distressing thoughts about their appearance with support from a parent or caregiver.
GothenburgAges 12–17 - NCT06256380Recruiting
Comparing two therapies for teens with eating disorders
This trial compares two proven therapies for teenagers with eating disorders: one that focuses on the whole family (FBT) and another that works with the teen individually (CBT-E). It aims to find which approach works best for different teens.
BergenAges 12–18 - NCT06245031Enrolling by invitation
Long-term follow-up of sensory stimulation for Alzheimer's
This is a follow-up study for people who already completed the 12-month Hope Study (CA-0011). It tests long-term safety and effects of a gentle sensory stimulation device (light and sound) for Alzheimer's disease. You will continue using the device at home with a study partner.
Phoenix, ArizonaAges 50–92 - NCT06246929Recruiting
Healthy aging for Black adults with chronic pain and memory concerns
This study tests a program to help Black adults aged 50+ manage chronic pain and early memory changes. It compares two approaches to see which works better for improving daily life and thinking skills.
Boston, MassachusettsAges 50 years+ - NCT06227572Recruiting
Thinking and memory after sleep apnea treatment in Native Americans
This study looks at whether using a PAP (breathing) machine helps thinking and memory in Native American adults with sleep apnea. If you are 50 or older and just starting PAP therapy, researchers want to see how it affects your brain health.
Eagle Butte, South DakotaAges 40 years+ - NCT06157866Recruiting
Cognitive training with acupuncture for fibromyalgia pain
This study tests whether a type of mental training (cognitive training) can help your brain respond better to acupuncture for fibromyalgia pain. You would receive acupuncture while doing a thinking task, and the study will use brain scans to see how your brain changes.
Charlestown, MassachusettsAges 18–65 - NCT06107842Recruiting
Exercise program for older veterans' memory and thinking
This study tests whether an exercise program called Gerofit can help improve memory and thinking in older Veterans. If you join, you will take part in supervised exercise sessions to see how it affects your brain health.
West Los Angeles, CaliforniaAges 65 years+ - NCT06120361Recruiting
Primary care study for early cognitive decline
This research study looks at people who have noticed problems with memory or thinking (like trouble focusing or finding words) and visit their primary care doctor for help. It aims to better understand and diagnose conditions that cause these symptoms, such as Alzheimer's disease.
MalmöAges 40 years+ - NCT05877885Recruiting
Digital treatment for low motivation in older adults with depression
This study tests a digital therapy to improve apathy (feeling unmotivated or “checked out”) in people age 60+ who have depression. It also uses brain imaging (MRI) and questionnaires to see whether the treatment helps brain function linked to motivation.
Orlando, FloridaAges 60 years+ - NCT06102941Recruiting
Cognitive training for OCD in kids aged 8 to 12
This study tests a cognitive training program to help young children with OCD. It's designed for kids whose OCD is their main problem and who are not currently on medication or in other therapy.
New York, New YorkAges 8–12
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Common questions
- Are there clinical trials for cognitive?
- Yes. Clin2 currently lists 1,981 recruiting cognitive studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognitive trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognitive trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.