Clinical trials
Coronary artery disease clinical trials
Narrowing of the arteries that supply blood to the heart. We’re tracking 712 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06919562Recruiting
Better stent placement using imaging and newer scaffolds
This trial tests if using advanced imaging (like OCT or IVUS) to guide placement of a newer type of stent (bioresorbable scaffold) can reduce future stent problems. It is for people with stable coronary artery disease who need a stent in a main heart artery.
DordrechtAges 18 years+ - NCT06920927Recruiting
Testing an online decision aid for heart and kidney disease
This study is testing an online tool called 'My Heart and CKD' that helps people with both chronic kidney disease and heart disease make decisions about their care. The goal is to see if it is easy to use and helpful for patients and their doctors.
Calgary, AlbertaAges 18 years+ - NCT06186037RecruitingPhase 4
Lower-dose combo vs. higher-dose alone for heart artery disease
This trial compares a lower-dose cholesterol pill (rosuvastatin plus ezetimibe) to a higher-dose version of just rosuvastatin for people with mild to moderate heart artery blockages who have not had a stent or bypass. It aims to see which approach works better and is safer.
Suwon, Gyeonggi-doAges 19 years+ - NCT06910436Recruiting
AI timing and outcomes in heart attack study
This trial uses artificial intelligence to analyze ECG results and timing in patients with a type of heart attack called Non-STEMI (where the artery is narrowed but not fully blocked). The goal is to see if AI can help predict damage and outcomes, which could lead to better care.
Bolzano, BZAges 18 years+ - NCT06898021Recruiting
3D stent study for heart artery blockages
This trial tests a new way of placing stents in heart arteries using a special ultrasound guidance. It may be a good option if you have a heart condition needing a stent and the area to be stented is not too long.
AalstAges 18 years+ - NCT06898541Enrolling by invitation
A device to treat chest pain from small heart artery disease
This trial tests a device called the Coronary Sinus Reducer for people with chest pain caused by problems in the small arteries of the heart. The device is placed in a vein near the heart to improve blood flow and reduce symptoms.
RotterdamAges 40 years+ - NCT06896903Recruiting
Testing heart artery function with and without nitroglycerin
This study compares two ways of testing the small blood vessels in the heart to understand chest pain when no major blockages are found. It may help doctors learn more about why you have chest pain and how to treat it.
Plano, TexasAges 18 years+ - NCT04761991Recruiting
CMR vs CT scan for coronary artery disease
This study compares two heart-imaging tests—cardiac MRI (CMR) and CT—to see which better helps evaluate coronary artery disease in people with chest pain. You may be asked to have one of these scans as part of your heart work-up.
Leicester, LeicsAges 18 years+ - NCT06878729Recruiting
Comparing two ways to open a blocked heart artery
This trial tests two procedures—antegrade dissection/re-entry and the retrograde method—to treat a completely blocked artery. It compares which technique works better for patients with complex blockages.
Warsaw, WarsawAges 18 years+ - NCT06863155Recruiting
A thin heart stent for people on blood thinners
This trial tests a new type of heart stent in people who also take daily blood thinners. The stent is very thin and releases medicine over time to help keep the artery open, and the coating eventually dissolves. It may be a safer option for people on blood thinners who need a stent.
AlbaceteAges 18 years+ - NCT06843005Recruiting
Heart CT scan study for plaque changes in mild coronary disease
This study uses repeat CT scans of the heart to see how plaque buildup changes over time in people with mild, non-blocking coronary artery disease. It may help doctors decide on better treatments to prevent future heart problems.
Nanjing, JiangsuAges 18–80 - NCT06845410Recruiting
INR-CAD: inflammation-related coronary artery disease study
This study follows people who have both coronary artery disease (narrowed heart arteries) and signs of chronic inflammation to learn more about their condition, current treatments, and outcomes. It helps doctors understand how best to care for patients like you.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06831409Recruiting
Heart scan study for retired NFL players
This trial uses heart CT scans to measure plaque and blood flow in retired NFL players, helping understand heart risks.
Greenwood Village, ColoradoAges Any age - NCT06822894Recruiting
3-vessel ultrasound flow study in heart disease patients
This trial uses a special ultrasound to measure blood flow in three main heart arteries. It may help doctors better understand blockages and improve treatment planning.
BeijingAges 18 years+ - NCT06822712Recruiting
Sirolimus-coated balloon for heart artery branch blockages
This trial tests a new balloon coated with sirolimus (a drug that helps prevent re-blockage) for treating blocked arteries at branch points (bifurcations) in the heart. If you have a blocked artery at a branch point, this study may offer a way to treat the side branch without placing a stent there.
Lanzhou, GansuAges 18–80 - NCT06804499Recruiting
Coronary artery disease and sudden cardiac arrest study
This study is for people with coronary artery disease (blocked arteries in the heart) who live in the Pirkanmaa area of Finland. It will collect information and blood samples to better understand heart disease and sudden cardiac arrest.
Tampere, PirkanmaaAges 18 years+ - NCT06814587Recruiting
New imaging for heart muscle damage after a heart attack
This study uses special imaging scans (MRI and PET) to look at the health of the heart muscle in people with advanced heart failure caused by blocked arteries. The goal is to better predict recovery after bypass surgery.
Dallas, TexasAges 20–80 - NCT06800430Recruiting
Studying graft problems after bypass surgery
This study looks at why some bypass grafts fail over time. It may help find better ways to treat or prevent graft problems in people who have had coronary artery bypass surgery.
Edinburgh, MidlothianAges 18 years+ - NCT06794359Enrolling by invitation
Comparing minimally invasive vs. traditional bypass for multi-vessel heart disease
This study compares two types of heart bypass surgery for people with blockages in multiple heart arteries: a newer, less invasive technique (minimally invasive CABG) versus the traditional open-chest approach. It aims to see which approach leads to better recovery and outcomes.
São Paulo, São PauloAges 18 years+ - NCT04634240Recruiting
Staged heart bypass plus TAVR versus TAVR alone
This study compares doing a staged coronary bypass (revascularization) along with a valve procedure (TAVR) versus doing TAVR and medical treatment alone. It aims to see which approach better helps people with both aortic valve narrowing and coronary artery disease.
Huntsville, AlabamaAges Any age - NCT06779630Recruiting
Study of a 48mm drug-coated stent for long coronary artery blockages
This trial tests a longer-than-usual drug-coated stent (Orsiro Mission) for treating long blockages in heart arteries. It aims to see if the stent is safe and effective for people with coronary artery disease.
Concord, CaliforniaAges 18 years+ - NCT06736665Recruiting
Comparing two ways to treat hardened calcium in heart arteries
This trial compares two techniques (orbital atherectomy and intravascular lithotripsy) to break up tough calcium deposits in the heart's arteries that can block blood flow. If you have a calcified nodule and are having a non-emergency procedure to open a blocked artery, this study may help guide which method works best.
Alicante, AlicanteAges 18 years+ - NCT06736899Recruiting
Orbital atherectomy versus standard care for calcified branch blockages
This trial compares a special device called orbital atherectomy to the usual procedure for treating hardened, calcified blockages that occur where a coronary artery branches. It aims to see which approach works better for patients needing a stent.
AlicanteAges 18 years+ - NCT06705751Recruiting
Faster diagnosis of abnormal coronary artery origin
This study tests a new, faster way to diagnose an uncommon heart condition where one of the main arteries (the coronary artery) starts from the wrong place on the aorta. The goal is to help doctors find and treat it sooner.
San Donato Milanese, ItaliaAges 6 years+
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Common questions
- Are there clinical trials for coronary artery disease?
- Yes. Clin2 currently lists 712 recruiting coronary artery disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a coronary artery disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a coronary artery disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.