Clinical trials
Coronary artery disease clinical trials
Narrowing of the arteries that supply blood to the heart. We’re tracking 713 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06025305Enrolling by invitation
Using AI to find dangerous heart plaque on CT scans
This study uses artificial intelligence to look at CT scans of the heart to find which fatty deposits (plaque) in the arteries might be dangerous. It may help doctors better predict heart attacks.
Nanjing, JiangsuAges 18 years+ - NCT06002932Recruiting
Comparing one-stent with drug balloon vs. two-stents for heart artery branches
This study compares two ways to treat a narrowed heart artery where a smaller branch vessel is also blocked. One approach uses a drug-coated balloon on the side branch, while the other places a second stent. The goal is to see which method works better for patients like you.
Suwon, Gyeonggi-doAges 19 years+ - NCT06001073Recruiting
Heart and brain disease health prediction study
This study uses advanced health data to predict how heart and brain conditions may progress. It aims to help doctors provide better care for people with these diseases.
Xi'an, ShaanxiAges 3–80 - NCT05643651RecruitingPhase 4
Rivaroxaban for kids with large heart artery aneurysms after Kawasaki disease
This trial studies whether rivaroxaban (a blood thinner) can help prevent dangerous clots in children age 2 and older who have “giant” coronary artery aneurysms after Kawasaki disease. Doctors will see if it’s safe and tolerable for children who are also on standard anti-clot/anti-platelet medications for the next 3 months.
Shanghai, Shanghai MunicipalityAges 2–18 - NCT07635407Recruiting
Virtual Stent Planning to Improve Heart Artery Procedures
This trial tests whether using computer software to virtually plan stent placement before your heart procedure leads to better outcomes. The goal is to optimize how stents are positioned in your coronary arteries.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05931783Recruiting
Compare two ways to use an artery during heart bypass
This study compares two surgical techniques for heart bypass: using the left internal thoracic artery in one specific way versus another. It may help improve how well the bypass works in people who need bypass surgery for multiple blocked heart arteries.
GrazAges 18–80 - NCT05913999Enrolling by invitation
PET and heart scans during early chemotherapy
This trial studies how a specialized heart imaging test (PET/MPI) changes during the start of chemotherapy for cancer patients. It may help researchers understand whether this monitoring approach detects heart strain early and keeps patients safer during treatment.
Los Angeles, CaliforniaAges 18 years+ - NCT07683585Recruiting
Comparing blood pressure drugs after heart stent placement
This trial compares two different combinations of blood pressure medicines to see which works better for people who have had a heart stent placed. It may help find the best treatment plan for controlling blood pressure after the procedure.
MoscowAges 50–70 - NCT05908331Recruiting
Balloon treatment test for narrowed stents in heart arteries
This trial tests whether a special drug-coated balloon (“MagicTouch”) can treat re-narrowing inside a previously placed stent. It may help patients whose stent has become blocked again, by improving blood flow and reducing repeat narrowing.
Birmingham, AlabamaAges 18–110 - NCT05860400Recruiting
Testing add-on treatment to calm artery inflammation after heart procedures
This study looks at whether a comprehensive add-on treatment—starting with immune medicine and then a heart procedure when needed—can improve outcomes for people whose coronary artery disease is getting worse quickly. It focuses on cases where inflammation is likely driving new artery blockages or worsening chest pain.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05845489RecruitingPhase 4
Clopidogrel to prevent heart problems from minor artery plaque
This trial tests whether clopidogrel (a blood-thinning medicine) can prevent future heart attacks or strokes in people who have early, “subclinical” plaque in their heart arteries. You may be considered if scans show plaque but not major artery blockage that needs a procedure.
Seoul, OtherAges 40 years+ - NCT05841199Recruiting
Study heart blood flow during fast heart rates
This study measures how well blood flows through the heart when the heart rate is increased during a heart procedure. It may help doctors better understand coronary (heart artery) blood flow and how to guide treatment when you need angiography or angioplasty.
LondonAges 18 years+ - NCT05800002Recruiting
IVUS-guided stent placement for badly calcified heart arteries
This trial studies a heart procedure that uses a special camera to guide where to place a drug-coated stent in an artery with heavy calcium. It may help improve how well the stent fits and works for people with certain types of coronary artery blockages.
Nanjing, JiangsuAges 18 years+ - NCT05799092Recruiting
Invasive vs non-invasive test for less-severe blocked heart arteries
This study compares two approaches to evaluating and treating people with symptoms of blocked heart arteries that are not “high-risk.” It may help doctors choose the safest, most effective next step for you by comparing invasive testing versus non-invasive evaluation.
Bucheon-siAges 19 years+ - NCT05782777Recruiting
Cholesterol medicines after stent: combo pill vs single pill
This trial compares two cholesterol-lowering treatment plans after a heart procedure where new drug-eluting stents were placed: a combination of high-intensity statin plus ezetimibe versus high-intensity statin alone. It may help find which option lowers cholesterol more effectively and safely over the first year after the procedure.
SeoulAges 19 years+ - NCT01311323Recruiting
Testing heart procedures to fully open blocked coronary arteries
This trial compares different ways to treat serious heart artery blockages in people with a recent heart attack or unstable chest pain. It aims to see which revascularization approach works best when doctors think the heart arteries can be fully treated.
Chrzanów, MalopolskaAges 18 years+ - NCT05761067Recruiting
Trial for advanced heart weakness with low pumping ability
This study looks at treatment options for adults with significantly reduced heart pumping strength and extensive coronary artery disease. It may help people who are at higher risk due to widespread blocked heart arteries, but eligibility depends on recent heart events and bleeding risk.
GothenburgAges 18 years+ - NCT05775445Recruiting
People with very blocked or very normal coronary arteries
This study compares people with very severe coronary artery disease to those without significant disease, using heart imaging data. It aims to understand what differs between extreme cases and how that information could guide future care.
SingaporeAges 21–99 - NCT05775354Enrolling by invitation
Early heart disease check-in in adults age 50–80
This study aims to improve early detection of heart and blood vessel problems by adding further research after routine care. It may help you by making sure your heart risk is monitored more closely, if you’re eligible and agree to the additional steps.
UtrechtAges 50–80 - NCT05770349Recruiting
Heart failure patients having bypass surgery are studied
This study looks at tiny structures inside heart muscle cells (especially “power stations” in the cells) in people with certain types of heart failure who are getting coronary bypass surgery. It may help researchers better understand what changes happen in the heart and how this could guide future care.
TomskAges 18 years+ - NCT05731687Recruiting
Balloon or two-stent approach for clogged bifurcation arteries
This trial compares two ways to open a specific type of heart blockage that involves both a main artery and a side branch. It tests whether using a drug-coated balloon (“hybrid strategy”) works as well as using a planned two-stent approach (“stepwise provisional strategy”).
Eindhoven, North BrabantAges 18 years+ - NCT05722145Enrolling by invitation
Study to assess heart artery blockage risk from CT scans
This study looks at how likely people are to have coronary artery disease (heart artery blockage) based on results from CT scans. It may help doctors better estimate risk and decide what follow-up care you may need.
Singapore, SingaporeAges 21–99 - NCT05732701Recruiting
Personalized blood thinner plan after stent placement
This trial tests an algorithm (computer-guided plan) to choose the best “dual antiplatelet therapy” (two blood-thinning medicines) after a coronary stent. It aims to improve outcomes after the procedure while reducing avoidable problems from the medicines.
Banja LukaAges 18 years+ - NCT05714241Recruiting
Blood tests to study heart pain with blocked-unblocked arteries
This study looks at blood “biomarkers” and platelet function to better understand INOCA (heart-related chest pain despite no major artery blockage). You may be eligible if you have INOCA and are already taking aspirin, and if you haven’t taken certain blood-thinner or platelet-altering medicines recently.
RomeAges 18 years+
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Common questions
- Are there clinical trials for coronary artery disease?
- Yes. Clin2 currently lists 713 recruiting coronary artery disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a coronary artery disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a coronary artery disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.