Clinical trials
Coronary artery disease clinical trials
Narrowing of the arteries that supply blood to the heart. We’re tracking 731 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07296744Recruiting
Study of a heart pump for high-risk angioplasty
This trial tests a new device called the Supira system to support the heart during a high-risk procedure to open blocked arteries. It is for people who are stable enough to wait for the procedure (not in emergency or shock).
Loma Linda, CaliforniaAges 18–90 - NCT01311323Recruiting
Testing heart procedures to fully open blocked coronary arteries
This trial compares different ways to treat serious heart artery blockages in people with a recent heart attack or unstable chest pain. It aims to see which revascularization approach works best when doctors think the heart arteries can be fully treated.
Chrzanów, MalopolskaAges 18 years+ - NCT06601153Recruiting
Heart health study using CT scans and blood samples
This study looks at blood samples and CT scans from people with stable coronary artery disease to find new ways to predict and prevent future heart problems. If you've had or are about to have a cardiac CT and have blood stored, you might be able to join.
Pisa, ItalyAges 40–75 - NCT06603363Recruiting
Statin effects on heart artery plaques seen on CT scans
This trial studies how short-term statin therapy changes plaque buildup in heart arteries. It uses CT scans to see if statins can make plaques more stable and reduce heart risks.
Budapest, BudapestAges 45–75 - NCT06606821RecruitingPhase 4
Tirzepatide for heart health in people with overweight or obesity
This trial tests the weight‑loss medication tirzepatide (Mounjaro) in people who are overweight or have obesity and have stable coronary artery disease. The goal is to see if tirzepatide can reduce dangerous fatty plaque in heart arteries.
CopenhagenAges 18 years+ - NCT06631157Recruiting
Essential Pro study for routine hospital patients
This trial is studying the Essential Pro device or treatment in patients who are already using it as part of their normal hospital care. The goal is to see how well it works in everyday practice.
Lai Chi KokAges 18 years+ - NCT06670768Recruiting
Comparing two heart imaging tests for blocked arteries
This trial compares two heart imaging tests (SPECT and coronary CTA) to see if a newer method gives a clearer picture of blood flow. If you have been referred for one of these tests, you may be able to help by also having the other test done at no extra risk.
Budapest, BudapestAges 18 years+ - NCT06681740Recruiting
Breathing muscle training for heart disease patients
This study tests whether a special breathing exercise program can help people who have had a heart attack and a procedure to open blocked heart arteries. The exercises strengthen the muscles you use to breathe, which may improve your recovery and quality of life.
MálagaAges 18–80 - NCT06686121RecruitingPhase 3
Improving walking after leg artery surgery for PAD
This trial tests whether drinking beetroot juice and doing home-based exercise can improve walking ability after you've had a procedure to open up blocked leg arteries. It's for people who are ready to start a walking program and want to avoid surgery.
Tucson, ArizonaAges 18 years+ - NCT06692140Recruiting
Comparing two types of stents for heart artery treatment
This trial compares a newer type of stent (with very thin struts and a coating that dissolves) to a standard stent in people having a heart artery procedure. It aims to see if the new stent works as well or better.
AalborgAges 18 years+ - NCT06700720RecruitingPhase 2
YN001-004 for coronary artery disease
This trial tests a new medicine (YN001) in people with coronary atherosclerosis (plaque buildup in heart arteries). It aims to see if the drug can help improve artery narrowing and heart health.
Canberra, Australian Capital TerritoryAges 18–75 - NCT06705751Recruiting
Faster diagnosis of abnormal coronary artery origin
This study tests a new, faster way to diagnose an uncommon heart condition where one of the main arteries (the coronary artery) starts from the wrong place on the aorta. The goal is to help doctors find and treat it sooner.
San Donato Milanese, ItaliaAges 6 years+ - NCT06706323Recruiting
Depression after heart surgery study
This study looks at depressive symptoms in people who have had heart bypass surgery. It aims to understand how patients feel emotionally after surgery and may help improve care.
ZurichAges 18–90 - NCT07683585Recruiting
Comparing blood pressure drugs after heart stent placement
This trial compares two different combinations of blood pressure medicines to see which works better for people who have had a heart stent placed. It may help find the best treatment plan for controlling blood pressure after the procedure.
MoscowAges 50–70 - NCT07635407Recruiting
Virtual Stent Planning to Improve Heart Artery Procedures
This trial tests whether using computer software to virtually plan stent placement before your heart procedure leads to better outcomes. The goal is to optimize how stents are positioned in your coronary arteries.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06710210Recruiting
Hybrid scaffold-balloon vs standard stent for long blockages
This trial tests a new way to treat long, narrow blockages in heart arteries. Instead of using a standard permanent metal stent, doctors will combine a temporary scaffold with a special balloon that releases medication. The goal is to see if this approach works as well as or better than the usual metal stent.
Geneva, Canton of GenevaAges 18 years+ - NCT06711822Recruiting
Shockwave catheter for calcified heart artery blockages
This study tests a new catheter device (ShockPulse-10) that uses shockwaves to crack calcium in heart arteries before placing a stent. It is designed for people with hard, calcified blockages that are difficult to treat with balloons alone.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06736665Recruiting
Comparing two ways to treat hardened calcium in heart arteries
This trial compares two techniques (orbital atherectomy and intravascular lithotripsy) to break up tough calcium deposits in the heart's arteries that can block blood flow. If you have a calcified nodule and are having a non-emergency procedure to open a blocked artery, this study may help guide which method works best.
Alicante, AlicanteAges 18 years+ - NCT06767345RecruitingPhase 4
Comparing two cholesterol medicines for plaque stabilization
This study compares two ways to lower cholesterol and stabilize artery plaque in people with coronary artery disease who are having a stent procedure. It tests whether a moderate statin plus ezetimibe works as well as a high-intensity statin alone for stabilizing plaque.
Seoul, SeoulAges 18 years+ - NCT06775028Recruiting
Integrated care for older adults with atrial fibrillation
This trial is testing a new approach to care for older adults with atrial fibrillation (an irregular heartbeat) who also have other health conditions. It aims to see if a more integrated, team-based care plan helps improve their overall health and quality of life.
HaskovoAges 65 years+ - NCT06779110Recruiting
OCT vs. X-ray guidance for treating re-blocked stents
This study compares the standard X-ray guidance (angiography) with a more detailed imaging test (OCT) to guide treatment for a re-blocked stent. It aims to see which method leads to better outcomes for patients with in-stent renarrowing.
Aosta, AostaAges 18–99 - NCT06793774Recruiting
Using CT scans and AI to evaluate heart artery risk
This study uses a CT scan of your heart (CCTA) and advanced computer analysis to see how well it can predict heart risks compared to detailed inside-look tests (IVUS, OCT, NIRS). If you have chest pain and have had certain heart scans, this trial may help doctors understand your condition better.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06793787Recruiting
AI and advanced imaging to guide treatment of borderline heart blockages
This study uses advanced CT scans and a special camera (OCT) to look at borderline blockages in heart arteries more closely. It aims to see if artificial intelligence can help decide which blockages need a stent and which can be treated with medicine alone.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06794684Recruiting
Watching Plaque in Heart Arteries Over Time
This study uses CT scans and special camera images inside your arteries to watch how plaque buildup in heart arteries changes over time. It may help you understand your risk and guide future treatment.
ShanghaiAges 18 years+
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Common questions
- Are there clinical trials for coronary artery disease?
- Yes. Clin2 currently lists 731 recruiting coronary artery disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a coronary artery disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a coronary artery disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.