Clinical trials
Coronary artery disease clinical trials
Narrowing of the arteries that supply blood to the heart. We’re tracking 731 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06916520RecruitingPhase 4
Reduced dose prasugrel alone after stent placement
This trial tests if a lower dose of prasugrel, taken alone (without aspirin), is safe and works well for people who have had a stent placed for chest pain or a heart attack. It might be an option for those who need to simplify their medication routine.
AmsterdamAges 18 years+ - NCT06958016Recruiting
Tryptase levels in stable coronary artery disease
This study looks at levels of tryptase, a protein in your blood, in people with stable coronary artery disease. It aims to see if these levels are linked to heart health, which could help doctors better understand and manage your condition.
Athens, AtticaAges 18–85 - NCT06794359Enrolling by invitation
Comparing minimally invasive vs. traditional bypass for multi-vessel heart disease
This study compares two types of heart bypass surgery for people with blockages in multiple heart arteries: a newer, less invasive technique (minimally invasive CABG) versus the traditional open-chest approach. It aims to see which approach leads to better recovery and outcomes.
São Paulo, São PauloAges 18 years+ - NCT06075420Recruiting
Shorter blood thinner use after GENOSS stent in heart disease
This trial tests whether a shorter course of dual antiplatelet therapy (two blood thinners) is safe and effective for people who have received a GENOSS stent for coronary artery disease. It aims to reduce the risk of bleeding while still preventing heart attacks.
Wŏnju, Gangwon StateAges 19 years+ - NCT05782777Recruiting
Cholesterol medicines after stent: combo pill vs single pill
This trial compares two cholesterol-lowering treatment plans after a heart procedure where new drug-eluting stents were placed: a combination of high-intensity statin plus ezetimibe versus high-intensity statin alone. It may help find which option lowers cholesterol more effectively and safely over the first year after the procedure.
SeoulAges 19 years+ - NCT02301663Recruiting
Stress test study of heart blood-flow issues in adults
This study tests a new kind of stress test to understand how small blood-vessel heart problems relate to heart relaxation problems in people with angina (chest pain) but no blocked arteries. It may help doctors learn better ways to diagnose and guide treatment for these conditions.
Los Angeles, CaliforniaAges 18–60 - NCT07159087Enrolling by invitation
New drug balloon for re-narrowed stents
This trial tests a new drug-coated balloon (Genoss SCB) versus an existing one (SeQuent Please NEO) for people whose heart stents have re-narrowed. It aims to see which balloon better keeps the artery open.
Gyeonggi-doAges 19 years+ - NCT06410313Recruiting
New drug-coated stent for thigh artery disease
This study tests a new drug-coated stent to improve blood flow in the thigh artery for people with leg pain or discomfort from narrowed arteries. It aims to see if the stent is safe and works well.
Atlanta, GeorgiaAges 18–120 - NCT07407738Recruiting
A trial of a shockwave device for calcified heart arteries
This trial tests a new device that uses sound waves to break up calcium deposits in heart arteries before placing a stent. It is for people with severely hardened arteries that are hard to treat with standard methods.
LyonAges 18 years+ - NCT07400406Recruiting
A new MRI test to see calcified heart arteries
This trial tests a special MRI using a contrast agent called ferumoxytol to better see calcium buildup in heart arteries. It may help people who need a coronary angiogram and have some calcium visible on a prior CT scan.
Nanjing, JiangsuAges 18–75 - NCT07093788Recruiting
Comparing two ways to treat hard calcium in heart arteries
This trial tests two methods for breaking up heavy calcium buildup in heart arteries before placing a stent. It compares a specialized high-pressure balloon to a device that uses shockwaves.
Lianyungang, JiangsuAges 18–80 - NCT07195149RecruitingPhase 3
Aspirin dose comparison after bypass surgery
This trial tests whether a lower dose of aspirin combined with another blood thinner (prasugrel) after bypass surgery is as safe and effective as a higher dose. It is for people with stable heart disease who are scheduled for bypass surgery and have not had a recent heart attack.
BialystokAges 18 years+ - NCT07172620Recruiting
Heart bypass surgery without clamping the aorta
This study tests a special technique for heart bypass surgery that avoids clamping the aorta. It may help people with hardened arteries in the aorta who need bypass surgery but are not good candidates for standard clamping.
Beijing, Beijing MunicipalityAges Any age - NCT06040073Recruiting
Study of heart artery blockages after heart attack
This study is for people who recently had a heart attack and need an angiogram. It looks at blockages that are not completely blocking blood flow to learn how they change over time.
BeijingAges 18 years+ - NCT07232069RecruitingPhase 3
Early heart disease trial for women and men with mild plaque buildup
This trial tests whether two medicines, a statin and colchicine, can slow or stop early heart artery plaque from growing in people who have mild plaque but no heart disease symptoms yet. It uses special CT scans to measure plaque over 2 years.
Birmingham, AlabamaAges 30–60 - NCT07041359RecruitingPhase 4
Traditional Chinese medicine for elderly heart disease patients with ongoing symptoms
This trial tests whether traditional Chinese medicine can help elderly patients with coronary heart disease who still have chest pain or discomfort despite standard treatments. It focuses on those who cannot have or have not fully benefited from procedures like stents or bypass surgery.
Beijing, Beijing MunicipalityAges 75–90 - NCT07068776Recruiting
Shockwave therapy to improve leg wound healing after bypass surgery
This trial tests if using shockwave therapy on leg veins during coronary artery bypass surgery can help the leg wound heal better. It may be a good fit if you need 2 or more vein grafts and have stable kidney function.
Innsbruck, TyrolAges 18 years+ - NCT06503640Recruiting
Microvascular dysfunction in angina patients
This study tests if chest pain with clear arteries is caused by tiny heart vessel problems. It may help find better treatments for patients whose arteries look normal on angiograms.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07696533Recruiting
Comparing two imaging tests for chronic coronary syndrome
This trial sees if a carotid ultrasound is as good as a CT calcium score to detect heart disease in people with chest pain. It may help avoid more expensive or less available scans.
HarrowAges 18 years+ - NCT05714241Recruiting
Blood tests to study heart pain with blocked-unblocked arteries
This study looks at blood “biomarkers” and platelet function to better understand INOCA (heart-related chest pain despite no major artery blockage). You may be eligible if you have INOCA and are already taking aspirin, and if you haven’t taken certain blood-thinner or platelet-altering medicines recently.
RomeAges 18 years+ - NCT04545112Enrolling by invitation
Testing a new heart bypass graft in people needing multi-vessel CABG
This study tests a new way to connect a bypass graft during heart bypass surgery for people with blocked heart arteries. The goal is to see if the new graft can be safely placed and works well enough to improve outcomes compared with the standard approach.
LeuvenAges 18 years+ - NCT06959524Recruiting
AGENT balloon for new heart artery blockages
This trial tests a drug-coated balloon (AGENT DCB) versus standard angioplasty/stenting for new blockages in heart arteries. It aims to see if the coated balloon works better and is safe for people who haven't had prior stents in that spot.
La Jolla, CaliforniaAges 18 years+ - NCT05699200Recruiting
Study of nerves involved in spontaneous coronary artery dissection
This study looks at how the body’s automatic “fight-or-flight” nerve system may relate to spontaneous coronary artery dissection (SCAD). If you have a SCAD history, your results may help researchers understand the condition better; if you’re a healthy control, your data are compared to SCAD patients.
Rochester, MinnesotaAges 18 years+ - NCT06822712Recruiting
Sirolimus-coated balloon for heart artery branch blockages
This trial tests a new balloon coated with sirolimus (a drug that helps prevent re-blockage) for treating blocked arteries at branch points (bifurcations) in the heart. If you have a blocked artery at a branch point, this study may offer a way to treat the side branch without placing a stent there.
Lanzhou, GansuAges 18–80
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Common questions
- Are there clinical trials for coronary artery disease?
- Yes. Clin2 currently lists 731 recruiting coronary artery disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a coronary artery disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a coronary artery disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.