Clinical trials
Coronary Heart Disease clinical trials
Below are recruiting coronary heart disease clinical trials, each written for real people, not researchers. We’re tracking 463 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05427370Recruiting
Compare bypass or stent treatment in weak heart patients
This study compares two ways to restore blood flow to the heart—bypass surgery (CABG) or stent procedure (PCI)—in people with a weak pumping heart. It looks at which approach works best when the heart muscle is not pumping well and there are multiple blocked heart arteries.
Los Angeles, CaliforniaAges 18 years+ - NCT07830719RecruitingPhase 2
Study of a new drug for heart disease and inflammation
This study tests a new medicine called YMI024 for people with stable coronary artery disease (blockages in heart arteries) and higher than normal levels of inflammation. The drug aims to reduce inflammation and may lower the risk of future heart problems.
Fairhope, AlabamaAges 18–80 - NCT06489119Recruiting
Studying plaque types in coronary artery disease with advanced imaging
This trial uses advanced imaging (OCT) and single-cell analysis to study different types of plaque in people with coronary artery disease. It aims to understand how these plaque types differ at a cellular level, which could lead to better treatments.
Harbin, HeilongjiangAges 18–85 - NCT06546761Recruiting
Heart imaging after carotid artery treatment
This study tests whether imaging the heart's arteries with a special CT scan can help find hidden blockages in people who just had treatment for a blocked carotid artery. It aims to prevent future heart problems.
RigaAges 50 years+ - NCT05643651RecruitingPhase 4
Rivaroxaban for kids with large heart artery aneurysms after Kawasaki disease
This trial studies whether rivaroxaban (a blood thinner) can help prevent dangerous clots in children age 2 and older who have “giant” coronary artery aneurysms after Kawasaki disease. Doctors will see if it’s safe and tolerable for children who are also on standard anti-clot/anti-platelet medications for the next 3 months.
Shanghai, Shanghai MunicipalityAges 2–18 - NCT07476703Recruiting
Extended study on the SCAPIS Stockholm reexamined group
This trial studies data and samples from people already taking part in the main SCAPIS reexamination study in Stockholm. It looks for new findings to help understand heart and lung health.
StockholmAges 56–74 - NCT06793774Recruiting
Using CT scans and AI to evaluate heart artery risk
This study uses a CT scan of your heart (CCTA) and advanced computer analysis to see how well it can predict heart risks compared to detailed inside-look tests (IVUS, OCT, NIRS). If you have chest pain and have had certain heart scans, this trial may help doctors understand your condition better.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT02582021Recruiting
Study of treatments and imaging in women with angina or HFpEF
This trial studies how heart disease affects the heart using heart imaging, and looks at people with chest pain/angina or heart failure with preserved pumping strength (HFpEF). It may help doctors better understand what’s driving symptoms and how best to evaluate these conditions.
Los Angeles, CaliforniaAges 18 years+ - NCT03497637Recruiting
Compare two ways to measure artery narrowing during heart procedures
This study compares two pressure-based methods (Vessel-FFR vs standard FFR) to decide how severe a heart artery narrowing is during a coronary angiogram or PCI. It may help patients and doctors choose which narrowings need treatment more accurately.
DresdenAges 18 years+ - NCT06878729Recruiting
Comparing two ways to open a blocked heart artery
This trial tests two procedures—antegrade dissection/re-entry and the retrograde method—to treat a completely blocked artery. It compares which technique works better for patients with complex blockages.
Warsaw, WarsawAges 18 years+ - NCT07316075Enrolling by invitation
Heart and metabolic health in silent pheochromocytoma or paraganglioma
This study looks at heart and metabolic health in people who have pheochromocytomas or paragangliomas that do not produce extra hormones. It aims to understand whether these 'silent' tumors affect cardiovascular and metabolic health, and how they compare to other cases.
AthensAges 18 years+ - NCT07660419Recruiting
Home cardiac rehab app for coronary plaque
This trial tests whether a smartphone-based home cardiac rehabilitation program can help slow or reverse plaque buildup in people with mild-to-moderate coronary artery narrowing. It may be an option if you have stable heart disease and can exercise at home with remote monitoring.
BeijingAges 18–70 - NCT07254572RecruitingPhase 4
Comparing diabetes drugs for heart health in prediabetes
This trial tests whether certain diabetes medications can help prevent worsening of heart disease in people who have prediabetes (higher than normal blood sugar, but not yet diabetes). It may be a good fit if you have known coronary artery disease and prediabetes.
WarsawAges 18–80 - NCT06314295Recruiting
AI heart ultrasound to find blocked arteries
This trial uses artificial intelligence to analyze heart ultrasound images and detect blocked arteries in people with suspected coronary artery disease. It aims to see if AI can accurately find problems without needing more invasive tests.
BeijingAges 18–90 - NCT07646444Recruiting
Study of OPN Balloon for Opening Hardened Heart Vessel Blockages
This is a follow-up study of patients who have already had a heart procedure using a special balloon (OPN balloon) to open calcified (hardened) blockages in heart arteries. Researchers will review records to see how well this balloon works and how patients recover.
Minneapolis, MinnesotaAges 18 years+ - NCT03378934RecruitingPhase 4
Berberine after stent placement to reduce blood-platelet effects
This trial studies whether berberine changes how strongly your platelets “stick together” after a coronary stent. It may help reduce risk related to clotting while you continue standard heart medicines (aspirin and clopidogrel).
Beijing, Beijing MunicipalityAges 18–70 - NCT02061436Recruiting
Chronic total occlusion procedure registry
This study collects data from patients who are having a procedure to open a completely blocked coronary artery. It may help improve future treatments for this condition.
Phoenix, ArizonaAges Any age - NCT05660798Recruiting
Switching from cigarettes to heat-not-burn to protect heart arteries
This study looks at whether switching from regular cigarettes to a tobacco heating product slows buildup of plaque in the heart arteries. You’d be guided through smoking change and monitored using heart scans, to see if artery plaque stays the same or improves.
WarsawAges 18–75 - NCT07480915Recruiting
Heart failure risk after bypass surgery
This study looks at how to predict major heart problems in people with heart failure who are scheduled for bypass surgery (CABG). It aims to improve risk assessment before the procedure.
Tomsk, Tomsk OblastAges Any age - NCT05873881RecruitingPhase 3
Colchicine and vitamin B1 for ischemic heart failure
This study tests whether colchicine and thiamine (vitamin B1) can improve outcomes in people with heart failure caused by blocked or narrowed heart arteries. It’s mainly for people with moderate-to-severe symptoms and reduced heart pumping ability.
Hamilton, OntarioAges 45 years+ - NCT06712862Recruiting
Testing heart muscle health with PET/MR scan
This study uses a special imaging test (PET/MR) to check if damaged heart muscle is still alive and can recover. It is for people with severe blocked arteries and weak heart pumping function who are planning bypass surgery or stem cell treatment.
Shanghai, Shanghai MunicipalityAges Up to 80 years - NCT05444452Recruiting
Stent treatment study for blocked heart arteries
This study tests a coronary stent approach for people with significantly blocked heart arteries. It may help by improving blood flow, and it compares treatment in a structured way while monitoring safety and outcomes.
SeoulAges 19 years+ - NCT07743021Recruiting
Blood sample study for better health screening
This study collects blood samples and health information over time to improve early detection of diseases. It may help researchers find ways to prevent serious conditions.
BalatonfüredAges 40 years+ - NCT07683585Recruiting
Comparing blood pressure drugs after heart stent placement
This trial compares two different combinations of blood pressure medicines to see which works better for people who have had a heart stent placed. It may help find the best treatment plan for controlling blood pressure after the procedure.
MoscowAges 50–70
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Common questions
- Are there clinical trials for coronary heart disease?
- Yes. Clin2 currently lists 463 recruiting coronary heart disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a coronary heart disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a coronary heart disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.