Clinical trials
Coronary Heart Disease clinical trials
Below are recruiting coronary heart disease clinical trials, each written for real people, not researchers. We’re tracking 477 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03854071Recruiting
Heart and health MRI testing in healthy people or patients
This study uses MRI (a scanning test) to develop new ways to measure heart function in both healthy volunteers and people with suspected or known heart disease. It may help researchers create better heart tests that could improve future diagnosis and monitoring.
Sheffield, EnglandAges 20–80 - NCT06275113Recruiting
Prevention program for heart and artery disease
This study tests a prevention program for people who have already had a heart event, stroke, or leg artery blockage. It is designed to help reduce the risk of future heart problems.
Canicattì, AGAges 18 years+ - NCT06793787Recruiting
AI and advanced imaging to guide treatment of borderline heart blockages
This study uses advanced CT scans and a special camera (OCT) to look at borderline blockages in heart arteries more closely. It aims to see if artificial intelligence can help decide which blockages need a stent and which can be treated with medicine alone.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06568159Recruiting
Sleep apnea treatment in heart patients
This study looks at how well people with heart disease or high heart risk follow their sleep apnea treatment, comparing a mouth device (MAD) to a CPAP machine. It aims to find which treatment works better for daily use.
MontpellierAges 18 years+ - NCT06705023RecruitingPhase 2
Fat-derived cell therapy for heart failure
This study tests whether taking a small amount of your own belly fat (through liposuction), processing it, and injecting the cells back into your heart can improve heart function in people with chronic heart failure due to blocked arteries. The trial is for patients whose heart pumps weakly (ejection fraction of 40% or less) and who are already on standard medications.
AstanaAges 21–80 - NCT04882488Recruiting
Testing heart scan measurements in severe aortic valve narrowing
This trial compares two pressure-based measurements of blood flow in the coronary arteries with a PET heart scan in people with severe aortic valve stenosis. It may help doctors choose the most accurate way to assess blood flow and guide care during valve treatment.
Bad Oeynhausen, North Rhine-WestphaliaAges 65 years+ - NCT05427370Recruiting
Compare bypass or stent treatment in weak heart patients
This study compares two ways to restore blood flow to the heart—bypass surgery (CABG) or stent procedure (PCI)—in people with a weak pumping heart. It looks at which approach works best when the heart muscle is not pumping well and there are multiple blocked heart arteries.
Los Angeles, CaliforniaAges 18 years+ - NCT07035171Recruiting
Pre-surgery exercise for heart bypass patients
This study tests whether starting a supervised exercise program before your first heart bypass surgery (CABG) is possible and helpful. If you are waiting for elective CABG and speak Danish, you may be able to join a prehabilitation program to get stronger before your operation.
CopenhagenAges 18 years+ - NCT07169201Recruiting
CT scan for heart in people with diabetes or heart disease
This study uses a special CT scan to look at your heart more closely. It may help people with known or suspected heart problems or type 2 diabetes.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06489119Recruiting
Studying plaque types in coronary artery disease with advanced imaging
This trial uses advanced imaging (OCT) and single-cell analysis to study different types of plaque in people with coronary artery disease. It aims to understand how these plaque types differ at a cellular level, which could lead to better treatments.
Harbin, HeilongjiangAges 18–85 - NCT04330287Recruiting
Study of heart health in adults aging with HIV
This study looks at how aging affects heart health in people who have HIV. It may help researchers find better ways to prevent or monitor heart problems over time.
Essen, NordrheinwestfalenAges 18 years+ - NCT06546761Recruiting
Heart imaging after carotid artery treatment
This study tests whether imaging the heart's arteries with a special CT scan can help find hidden blockages in people who just had treatment for a blocked carotid artery. It aims to prevent future heart problems.
RigaAges 50 years+ - NCT05643651RecruitingPhase 4
Rivaroxaban for kids with large heart artery aneurysms after Kawasaki disease
This trial studies whether rivaroxaban (a blood thinner) can help prevent dangerous clots in children age 2 and older who have “giant” coronary artery aneurysms after Kawasaki disease. Doctors will see if it’s safe and tolerable for children who are also on standard anti-clot/anti-platelet medications for the next 3 months.
Shanghai, Shanghai MunicipalityAges 2–18 - NCT07476703Recruiting
Extended study on the SCAPIS Stockholm reexamined group
This trial studies data and samples from people already taking part in the main SCAPIS reexamination study in Stockholm. It looks for new findings to help understand heart and lung health.
StockholmAges 56–74 - NCT06793774Recruiting
Using CT scans and AI to evaluate heart artery risk
This study uses a CT scan of your heart (CCTA) and advanced computer analysis to see how well it can predict heart risks compared to detailed inside-look tests (IVUS, OCT, NIRS). If you have chest pain and have had certain heart scans, this trial may help doctors understand your condition better.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT02582021Recruiting
Study of treatments and imaging in women with angina or HFpEF
This trial studies how heart disease affects the heart using heart imaging, and looks at people with chest pain/angina or heart failure with preserved pumping strength (HFpEF). It may help doctors better understand what’s driving symptoms and how best to evaluate these conditions.
Los Angeles, CaliforniaAges 18 years+ - NCT04748237Recruiting
CT heart scan for intermediate-risk chest pain
This study tests whether a special heart CT scan can help evaluate the cause of chest pain in people at intermediate risk for blocked heart arteries. It may help doctors decide what to do next after an emergency room visit.
StockholmAges 18 years+ - NCT03497637Recruiting
Compare two ways to measure artery narrowing during heart procedures
This study compares two pressure-based methods (Vessel-FFR vs standard FFR) to decide how severe a heart artery narrowing is during a coronary angiogram or PCI. It may help patients and doctors choose which narrowings need treatment more accurately.
DresdenAges 18 years+ - NCT06878729Recruiting
Comparing two ways to open a blocked heart artery
This trial tests two procedures—antegrade dissection/re-entry and the retrograde method—to treat a completely blocked artery. It compares which technique works better for patients with complex blockages.
Warsaw, WarsawAges 18 years+ - NCT07316075Enrolling by invitation
Heart and metabolic health in silent pheochromocytoma or paraganglioma
This study looks at heart and metabolic health in people who have pheochromocytomas or paragangliomas that do not produce extra hormones. It aims to understand whether these 'silent' tumors affect cardiovascular and metabolic health, and how they compare to other cases.
AthensAges 18 years+ - NCT07660419Recruiting
Home cardiac rehab app for coronary plaque
This trial tests whether a smartphone-based home cardiac rehabilitation program can help slow or reverse plaque buildup in people with mild-to-moderate coronary artery narrowing. It may be an option if you have stable heart disease and can exercise at home with remote monitoring.
BeijingAges 18–70 - NCT06314295Recruiting
AI heart ultrasound to find blocked arteries
This trial uses artificial intelligence to analyze heart ultrasound images and detect blocked arteries in people with suspected coronary artery disease. It aims to see if AI can accurately find problems without needing more invasive tests.
BeijingAges 18–90 - NCT07254572RecruitingPhase 4
Comparing diabetes drugs for heart health in prediabetes
This trial tests whether certain diabetes medications can help prevent worsening of heart disease in people who have prediabetes (higher than normal blood sugar, but not yet diabetes). It may be a good fit if you have known coronary artery disease and prediabetes.
WarsawAges 18–80 - NCT07646444Recruiting
Study of OPN Balloon for Opening Hardened Heart Vessel Blockages
This is a follow-up study of patients who have already had a heart procedure using a special balloon (OPN balloon) to open calcified (hardened) blockages in heart arteries. Researchers will review records to see how well this balloon works and how patients recover.
Minneapolis, MinnesotaAges 18 years+
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Common questions
- Are there clinical trials for coronary heart disease?
- Yes. Clin2 currently lists 477 recruiting coronary heart disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a coronary heart disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a coronary heart disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.