Clinical trials
Coronary Heart Disease clinical trials
Below are recruiting coronary heart disease clinical trials, each written for real people, not researchers. We’re tracking 463 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06084091Recruiting
Measuring heart oxygen levels during open-heart surgery
This study measures oxygen levels in the heart muscle during open-heart surgery using a light-based technique. You may qualify if you are an adult scheduled for this surgery and can provide consent.
Helsinki, UusimaaAges 18–90 - NCT06047028Recruiting
Heart MRI scan to assess tissue health
This study uses a special MRI scan to look at heart muscle metabolism in people with heart failure caused by blocked arteries. It may help doctors better understand which heart tissue is still alive and could recover.
Dallas, TexasAges 20–80 - NCT06041581Enrolling by invitation
Insomnia treatment study for heart health
This study tests whether treating insomnia can help lower your risk for heart disease. If you have trouble sleeping and certain heart risk factors, you may be able to join.
Indianapolis, IndianaAges 40 years+ - NCT06007248Recruiting
Study of inflammation-related coronary artery disease
This study compares two types of coronary artery disease: one linked to inflammation (IR-CAD) and the standard type (AS-CAD). If you have had a heart procedure and were recently hospitalized for worsening chest pain, this study may help doctors understand your condition better.
Beijing, Beijing MunicipalityAges 45–64 - NCT05860400Recruiting
Testing add-on treatment to calm artery inflammation after heart procedures
This study looks at whether a comprehensive add-on treatment—starting with immune medicine and then a heart procedure when needed—can improve outcomes for people whose coronary artery disease is getting worse quickly. It focuses on cases where inflammation is likely driving new artery blockages or worsening chest pain.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05932615Enrolling by invitation
Testing a new transcatheter valve for aortic valve narrowing
This trial studies how safe and effective the NAVITOR valve is for treating narrowed aortic valves placed through a catheter (no open-heart surgery). It may be an option if you’re at intermediate-to-low surgical risk and meet heart ultrasound/CT measurements.
Birmingham, AlabamaAges 18 years+ - NCT05935605Recruiting
Study pulmonary hypertension in heart failure and valve disease
This study looks at pulmonary hypertension—high blood pressure in the lung arteries—in people with certain heart conditions (heart failure with preserved or reduced pumping function, or significant valve disease). It may help doctors better understand how lung blood pressure changes in these heart problems and guide care.
Rochester, MinnesotaAges 18 years+ - NCT05841199Recruiting
Study heart blood flow during fast heart rates
This study measures how well blood flows through the heart when the heart rate is increased during a heart procedure. It may help doctors better understand coronary (heart artery) blood flow and how to guide treatment when you need angiography or angioplasty.
LondonAges 18 years+ - NCT05770349Recruiting
Heart failure patients having bypass surgery are studied
This study looks at tiny structures inside heart muscle cells (especially “power stations” in the cells) in people with certain types of heart failure who are getting coronary bypass surgery. It may help researchers better understand what changes happen in the heart and how this could guide future care.
TomskAges 18 years+ - NCT05775354Enrolling by invitation
Early heart disease check-in in adults age 50–80
This study aims to improve early detection of heart and blood vessel problems by adding further research after routine care. It may help you by making sure your heart risk is monitored more closely, if you’re eligible and agree to the additional steps.
UtrechtAges 50–80 - NCT05366153Recruiting
Plan to lower future heart attack risk after past cancer treatment
This trial tests whether a “risk-guided” care plan can help prevent coronary artery disease (the buildup that can lead to heart attacks) in people who had cancer treatment that can affect the heart. You may get closer heart risk monitoring and guidance to reduce risk factors, such as cholesterol—especially if you can safely take statins.
Hobart, TasmaniaAges 40–70 - NCT05722145Enrolling by invitation
Study to assess heart artery blockage risk from CT scans
This study looks at how likely people are to have coronary artery disease (heart artery blockage) based on results from CT scans. It may help doctors better estimate risk and decide what follow-up care you may need.
Singapore, SingaporeAges 21–99 - NCT05677386Enrolling by invitation
CT heart scan trial to prevent first heart problems
This trial uses a special CT scan of the heart’s arteries to better predict who is at risk of future heart problems. It may help your care team decide how best to lower risk early.
CopenhagenAges 40 years+ - NCT05698732Recruiting
Coroflex stent study for selected small heart artery blockages
This trial studies a new heart stent (called Coroflex ISAR NEO) for people who need a procedure to open a narrowed coronary artery. It may help improve long-term results for patients with certain small, short blockages who can safely take the required blood-thinning medicines.
Aix-en-ProvenceAges 18 years+ - NCT05647213RecruitingPhase 1
Skin biopsy study of stem-cell therapy for congenital heart disease
This early study takes a small skin sample to make a personalized type of heart stem cells in the future. It is testing whether this approach is safe and feasible for people with complex single-chamber congenital heart disease and advanced heart failure.
Rochester, MinnesotaAges 18–40 - NCT05267990Enrolling by invitation
CT calcium scan to prevent heart problems in diabetes
This trial studies whether using a heart CT “calcium score” to guide prevention can lower the chance of major heart disease in people with type 2 diabetes who have other heart risk factors. It may help by targeting prevention more personally, based on your calcium score.
YilanAges 40 years+ - NCT05044273Recruiting
Study of two new stents and their safety in adults
This study checks how safe and effective two types of heart stents (Synergy XD and Synergy Megatron) are after they are placed. You might consider it if you’re an adult getting one of these stents and can follow required clinic visits.
AnyangAges 19 years+ - NCT05100992Recruiting
Bifurcation heart procedure registry for adults
This study is a real-world registry that follows adults who are getting a specific type of heart stent procedure in a forked artery. It helps doctors learn what happens before and after the procedure and improve care.
Minneapolis, MinnesotaAges 18 years+ - NCT05124249Recruiting
Imaging tests to evaluate clogged heart arteries
This study looks at how well special heart imaging and pressure-based tests can evaluate coronary artery disease (clogged heart arteries). If you had testing for suspected heart artery disease, the study may help doctors compare how these measurements work.
GwangjuAges 18 years+ - NCT04676100Enrolling by invitation
International registry for cardiac rehabilitation programs
This study collects information about cardiac rehabilitation (CR) programs in lower-resource areas. It helps improve how CR is delivered and understood, especially where healthcare resources and awareness are limited.
DohaAges 18 years+ - NCT04674449Recruiting
Tests a targeted plan for people with chest pain from heart artery disease
This study aims to match people with angina (chest pain from heart artery problems) to the most helpful treatment plan based on their test results. It’s done around the time doctors are planning an invasive heart scan to look at the coronary arteries.
CorkAges 18 years+ - NCT04451044Enrolling by invitation
Guided heart stent planning using an inside pressure sensor
This study tests whether using a tiny pressure sensor in heart arteries during a procedure can better guide where to place a stent. It may help doctors choose the safest and most effective stent plan by more accurately measuring artery narrowing.
Birmingham, AlabamaAges 18 years+ - NCT04124120Recruiting
Single vs multiple bypass grafts for women heart surgery
This study compares outcomes of using one bypass graft versus multiple bypass grafts during coronary artery bypass surgery in women. It aims to see which approach leads to better recovery and heart outcomes for eligible patients.
Los Angeles, CaliforniaAges 18 years+ - NCT03674255Enrolling by invitation
Tests how accurate heart ultrasound is during stress
This study checks how well a heart ultrasound (echocardiography) works when your heart is at rest and under stress. You may benefit by getting closer attention to how the test is done, especially if it’s being used to look for blocked-heart-blood-flow problems.
Ages 18 years+
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Common questions
- Are there clinical trials for coronary heart disease?
- Yes. Clin2 currently lists 463 recruiting coronary heart disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a coronary heart disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a coronary heart disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.