Clinical trials
Critical Care clinical trials
Below are recruiting critical care clinical trials, each written for real people, not researchers. We’re tracking 183 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07732114Recruiting
Liver vein vs. heart echo to check right heart function on a ventilator
This study compares a liver vein ultrasound method with a standard heart ultrasound for checking how well the right side of the heart is pumping in patients who are on a breathing machine (ventilator). If you are on a ventilator and can get a clear ultrasound of your heart and liver veins, you may be able to join.
Alexandria, Shebin El-KomAges 18 years+ - NCT07837128Recruiting
Gentle breathing support in intensive care
This trial tests two ways of using a breathing machine (ventilator) in the ICU. One method is more gentle on the lungs, and the goal is to see if it helps patients recover faster.
Amsterdam, NLAges 18 years+ - NCT07740304Recruiting
Blood flow test to predict survival in sepsis patients
This study checks if a simple blood flow measurement can help predict which patients with sepsis are at higher risk of dying within 28 days. The goal is to see if this test can guide treatment decisions in the ICU.
Edirne, MerkezAges 18 years+ - NCT07639359RecruitingPhase 2
Ketamine for depression in intensive care patients
This study tests whether low-dose ketamine infusions can reduce depressive symptoms in patients staying in the intensive care unit for at least 6 days. Ketamine is a medication that may work differently than standard antidepressants and could provide faster relief.
Jacksonville, FloridaAges 18–99 - NCT06697470Recruiting
Ultrasound and fluid monitoring in the ICU
This study uses ultrasound and electrical impedance (skin electrodes) to track fluid balance in the muscles and tissues of ICU patients. It aims to see if these tools can help doctors better manage fluids during your stay.
Boussu, HainautAges 18 years+ - NCT07303335Enrolling by invitation
Sarcopenia in ICU patients on long-term ventilation
This study checks for muscle loss (sarcopenia) in ICU patients who need a breathing machine (mechanical ventilation). It aims to track how muscle health changes during hospital stay.
Terrassa, BarcelonaAges 18 years+ - NCT06791889Recruiting
Tracking bacteria in blood of ICU sepsis patients
This study uses a highly sensitive blood test (DdPCR) to quickly find and monitor harmful bacteria in ICU patients with sepsis, aiming to improve early detection and treatment.
WuhanAges 18 years+ - NCT07188350Recruiting
Electrical muscle stimulation for patients on a breathing machine
This trial tests whether low-level electrical pulses to the leg muscles can help prevent weakness in patients who need a breathing tube (ventilator) for more than 48 hours. It aims to see if this treatment helps patients recover faster.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT07124442Recruiting
Muscle function study for ICU patients
This study looks at muscle function and disease severity in people who have been in the intensive care unit (ICU) for at least 48 hours. It aims to understand how muscle problems relate to recovery and risk, without requiring a breathing machine.
Istanbul, EsenyurtAges 18 years+ - NCT07035106Recruiting
Using wearables to track recovery after ICU
This study tests if a wearable device and health summaries can help people recover after a stay in the intensive care unit (ICU). It is for people who have diabetes or heart problems and left the ICU within the last 2 years.
ViennaAges 18–65 - NCT06840756RecruitingPhase 4
Does donor-patient sex matching improve blood transfusion outcomes?
This trial tests whether giving ICU patients blood from a donor of the same sex (male-to-male or female-to-female) leads to better recovery compared to mismatched transfusions. The goal is to see if matching donor and patient sex makes a difference in how well patients do.
Hamilton, OntarioAges 18 years+ - NCT06411561Recruiting
Boosting memory after ICU stay for older adults
This study tests a combination of activities (like cognitive training and exercise) to help older adults recover thinking and memory after a serious illness in the ICU. It may help you regain sharpness and independence after leaving the intensive care unit.
Seattle, WashingtonAges 60 years+ - NCT06721923Recruiting
Comparing protein delivery methods in critically ill children
This study looks at whether giving protein continuously or all at once is better for children in intensive care. The goal is to find the most effective way to support recovery.
Vancouver, British ColumbiaAges 1–11 - NCT05830721Recruiting
Monitoring leg pressure in adults on life-support
This trial tests a device that continuously measures pressure in an arm or leg to help detect compartment syndrome in people on a heart-lung machine (VA-ECMO). It may help clinicians act sooner if pressure becomes dangerous, potentially reducing complications.
Baltimore, MarylandAges 18 years+ - NCT07848165Recruiting
Probiotics to prevent pneumonia in children on breathing machines
This trial tests whether giving probiotics (good bacteria) can help prevent pneumonia in children who are on a breathing machine in the intensive care unit. If your child is on a ventilator, these friendly bacteria might help keep their lungs healthy.
Tanta, Al GharbiaAges 1 month–18 years - NCT06574672Recruiting
Palliative care in the medical ICU
This study tests whether adding palliative care (comfort and support care) to usual MICU treatment helps patients and families. It takes place in the medical intensive care unit.
St Louis, MissouriAges 18 years+ - NCT07460141Recruiting
Blood tests to predict death risk after surgery in the ICU
This study is looking at whether certain blood tests can help predict the risk of death after surgery in ICU patients. If you have had surgery and are now in the ICU, your blood samples may help doctors learn more.
TrabzonAges 18 years+ - NCT07323472Recruiting
Body positioning and breathing in critically ill patients on ventilators
This study tests whether turning patients on their side affects their breathing and lung health. It aims to improve care for people who need a breathing machine.
Recife, PernamuAges 18 years+ - NCT06584604Recruiting
Calibrating esophageal balloon for breathing machine patients
This trial is testing how to calibrate an esophageal balloon (a thin tube that measures pressure in your chest) for people on a breathing machine. If you are already sedated and have this tube in place, participating may help doctors get more accurate readings to improve your breathing support.
Leiden, South HollandAges 18 years+ - NCT07128446Recruiting
Goal setting with COPM in the PICU
This trial is testing a new way to set goals for children in the pediatric intensive care unit. Researchers want to see if a tool called COPM helps caregivers and therapists work together to choose the most important rehab goals.
Seoul, Gangnam-guAges 1–18 - NCT06692400Recruiting
Suctioning, pain, and blood markers in intubated patients
This study looks at how routine suctioning of the breathing tube affects pain levels and certain substances in the blood in adults who are on a breathing machine for serious infections like flu, pneumonia, COVID, or sepsis. It may help doctors better understand and manage your comfort during this procedure.
Loma Linda, CaliforniaAges 18 years+ - NCT06532994Recruiting
Prediction tool for recovery after critical illness
This study looks at how well people recover after critical illness. It tests a prediction tool to help guide rehabilitation for patients who needed a breathing machine and started rehab in the ICU.
Wuhan, HubeiAges 18–90 - NCT05279547Recruiting
Bed-cycle exercise study to test muscle oxygen during ICU care
This trial tests whether brief “interval” bed-cycling changes how well your leg muscles use oxygen compared with steady cycling. It’s meant for carefully selected ICU patients who can safely do active cycling while on ventilator support.
LeuvenAges 18 years+ - NCT07401420Recruiting
Study on life-sustaining treatments in critically ill children
This study asks experienced critical care doctors about decisions they make when providing life-sustaining treatments to critically ill children, especially around end-of-life care. Your insights could help improve how these difficult situations are handled.
GothenburgAges 18 years+
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Common questions
- Are there clinical trials for critical care?
- Yes. Clin2 currently lists 183 recruiting critical care studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a critical care trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a critical care trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.