Clinical trials
Critical Care clinical trials
Below are recruiting critical care clinical trials, each written for real people, not researchers. We’re tracking 188 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06832722RecruitingPhase 1/Phase 2
Invobenitug (Procizumab) for critical heart conditions
This trial tests a new drug, Invobenitug, for patients in shock caused by heart attack, infection, or sudden worsening of heart failure. It aims to see if the drug can help stabilize blood pressure and improve outcomes.
YerevanAges 18–80 - NCT06501118Recruiting
Oxygen levels in ICU patients on breathing machines
This study tests whether giving a little more oxygen to ICU patients on breathing machines leads to better recovery. It compares usual oxygen levels to a more liberal target to see which is safer and more effective.
Aurora, ColoradoAges 18 years+ - NCT07013175Recruiting
Wise Choices in the Intensive Care Unit
This study looks at how decisions are made in the ICU. It may help improve care for adult patients in Swedish intensive care units.
StockholmAges 18 years+ - NCT05537298Recruiting
Help for muscle recovery after serious ICU illness
This trial looks at how to improve muscle strength and function after a stay in the ICU for sepsis or acute respiratory failure. If you recover from the illness but your muscles become weak, this study may test an approach to help rebuild strength faster.
Birmingham, AlabamaAges 18 years+ - NCT06681649Recruiting
ICU follow-up care for survivors and their caregivers
This study tests a bundle of follow-up care for ICU survivors and their caregivers after leaving the hospital. It aims to improve recovery and support for both patients and their families.
Kingston, OntarioAges 18 years+ - NCT07191743Recruiting
Functional Assessment in ICU Patients
This study observes how well adults in the intensive care unit (ICU) can function in daily activities, like moving and caring for themselves. It aims to understand recovery and may help improve care for future ICU patients.
Rio de Janeiro, Rio de JaneiroAges 18 years+ - NCT07307066Recruiting
Ventilation feedback study for lung protection in ARDS
This study tests a computer system that gives real-time breathing machine advice to help protect the lungs of patients with severe lung injury (ARDS). It may help doctors adjust the ventilator settings to cause less damage.
Qujing, YunnanAges 18–75 - NCT07732114Recruiting
Liver vein vs. heart echo to check right heart function on a ventilator
This study compares a liver vein ultrasound method with a standard heart ultrasound for checking how well the right side of the heart is pumping in patients who are on a breathing machine (ventilator). If you are on a ventilator and can get a clear ultrasound of your heart and liver veins, you may be able to join.
Alexandria, Shebin El-KomAges 18 years+ - NCT06840756RecruitingPhase 4
Does donor-patient sex matching improve blood transfusion outcomes?
This trial tests whether giving ICU patients blood from a donor of the same sex (male-to-male or female-to-female) leads to better recovery compared to mismatched transfusions. The goal is to see if matching donor and patient sex makes a difference in how well patients do.
Hamilton, OntarioAges 18 years+ - NCT07188350Recruiting
Electrical muscle stimulation for patients on a breathing machine
This trial tests whether low-level electrical pulses to the leg muscles can help prevent weakness in patients who need a breathing tube (ventilator) for more than 48 hours. It aims to see if this treatment helps patients recover faster.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT07740304Recruiting
Blood flow test to predict survival in sepsis patients
This study checks if a simple blood flow measurement can help predict which patients with sepsis are at higher risk of dying within 28 days. The goal is to see if this test can guide treatment decisions in the ICU.
Edirne, MerkezAges 18 years+ - NCT06411561Recruiting
Boosting memory after ICU stay for older adults
This study tests a combination of activities (like cognitive training and exercise) to help older adults recover thinking and memory after a serious illness in the ICU. It may help you regain sharpness and independence after leaving the intensive care unit.
Seattle, WashingtonAges 60 years+ - NCT06697470Recruiting
Ultrasound and fluid monitoring in the ICU
This study uses ultrasound and electrical impedance (skin electrodes) to track fluid balance in the muscles and tissues of ICU patients. It aims to see if these tools can help doctors better manage fluids during your stay.
Boussu, HainautAges 18 years+ - NCT06791889Recruiting
Tracking bacteria in blood of ICU sepsis patients
This study uses a highly sensitive blood test (DdPCR) to quickly find and monitor harmful bacteria in ICU patients with sepsis, aiming to improve early detection and treatment.
WuhanAges 18 years+ - NCT07035106Recruiting
Using wearables to track recovery after ICU
This study tests if a wearable device and health summaries can help people recover after a stay in the intensive care unit (ICU). It is for people who have diabetes or heart problems and left the ICU within the last 2 years.
ViennaAges 18–65 - NCT07093203Recruiting
Rezafungin for fungal infection in the belly
This trial tests how well rezafungin, an antifungal medicine, spreads in belly fluid when given during surgery for a suspected fungal infection in the abdomen. It aims to see if it's a good treatment option for patients needing abdominal surgery.
Vandœuvre-lès-Nancy, LorraineAges 18 years+ - NCT07124442Recruiting
Muscle function study for ICU patients
This study looks at muscle function and disease severity in people who have been in the intensive care unit (ICU) for at least 48 hours. It aims to understand how muscle problems relate to recovery and risk, without requiring a breathing machine.
Istanbul, EsenyurtAges 18 years+ - NCT07418242Recruiting
New markers for kidney risk after heart surgery
This study looks at whether certain blood or urine markers can predict kidney problems in people having high-risk heart surgery. The goal is to find early warning signs so doctors can take steps to protect your kidneys.
Shanghai, Shanghai MunicipalityAges 18–90 - NCT07303335Enrolling by invitation
Sarcopenia in ICU patients on long-term ventilation
This study checks for muscle loss (sarcopenia) in ICU patients who need a breathing machine (mechanical ventilation). It aims to track how muscle health changes during hospital stay.
Terrassa, BarcelonaAges 18 years+ - NCT06721923Recruiting
Comparing protein delivery methods in critically ill children
This study looks at whether giving protein continuously or all at once is better for children in intensive care. The goal is to find the most effective way to support recovery.
Vancouver, British ColumbiaAges 1–11 - NCT05830721Recruiting
Monitoring leg pressure in adults on life-support
This trial tests a device that continuously measures pressure in an arm or leg to help detect compartment syndrome in people on a heart-lung machine (VA-ECMO). It may help clinicians act sooner if pressure becomes dangerous, potentially reducing complications.
Baltimore, MarylandAges 18 years+ - NCT06574672Recruiting
Palliative care in the medical ICU
This study tests whether adding palliative care (comfort and support care) to usual MICU treatment helps patients and families. It takes place in the medical intensive care unit.
St Louis, MissouriAges 18 years+ - NCT05279547Recruiting
Bed-cycle exercise study to test muscle oxygen during ICU care
This trial tests whether brief “interval” bed-cycling changes how well your leg muscles use oxygen compared with steady cycling. It’s meant for carefully selected ICU patients who can safely do active cycling while on ventilator support.
LeuvenAges 18 years+ - NCT06584604Recruiting
Calibrating esophageal balloon for breathing machine patients
This trial is testing how to calibrate an esophageal balloon (a thin tube that measures pressure in your chest) for people on a breathing machine. If you are already sedated and have this tube in place, participating may help doctors get more accurate readings to improve your breathing support.
Leiden, South HollandAges 18 years+
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Common questions
- Are there clinical trials for critical care?
- Yes. Clin2 currently lists 188 recruiting critical care studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a critical care trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a critical care trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.