Clinical trials
Critical Care clinical trials
Below are recruiting critical care clinical trials, each written for real people, not researchers. We’re tracking 188 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06692400Recruiting
Suctioning, pain, and blood markers in intubated patients
This study looks at how routine suctioning of the breathing tube affects pain levels and certain substances in the blood in adults who are on a breathing machine for serious infections like flu, pneumonia, COVID, or sepsis. It may help doctors better understand and manage your comfort during this procedure.
Loma Linda, CaliforniaAges 18 years+ - NCT06532994Recruiting
Prediction tool for recovery after critical illness
This study looks at how well people recover after critical illness. It tests a prediction tool to help guide rehabilitation for patients who needed a breathing machine and started rehab in the ICU.
Wuhan, HubeiAges 18–90 - NCT07128446Recruiting
Goal setting with COPM in the PICU
This trial is testing a new way to set goals for children in the pediatric intensive care unit. Researchers want to see if a tool called COPM helps caregivers and therapists work together to choose the most important rehab goals.
Seoul, Gangnam-guAges 1–18 - NCT07323472Recruiting
Body positioning and breathing in critically ill patients on ventilators
This study tests whether turning patients on their side affects their breathing and lung health. It aims to improve care for people who need a breathing machine.
Recife, PernamuAges 18 years+ - NCT07460141Recruiting
Blood tests to predict death risk after surgery in the ICU
This study is looking at whether certain blood tests can help predict the risk of death after surgery in ICU patients. If you have had surgery and are now in the ICU, your blood samples may help doctors learn more.
TrabzonAges 18 years+ - NCT07656311Enrolling by invitation
Platelet size as early warning for cancer ICU patients
This study looks at whether the size of platelets in your blood when you enter the intensive care unit (ICU) can help predict your chances of recovery. It focuses on adults with cancer who are in the ICU for more than 24 hours and aims to find early signs of risk.
AnkaraAges 18 years+ - NCT06526533RecruitingPhase 3
Red blood cell transfusion thresholds for ECMO patients
This trial is testing whether a higher or lower threshold for red blood cell transfusions is better for people on ECMO (a heart-lung machine). It aims to find the safest way to manage transfusions during ECMO treatment.
Camperdown, New South WalesAges Any age - NCT06961227Recruiting
Comparing two breathing machine settings in the ICU
This trial compares two different ways a breathing machine can help you breathe. It uses a special imaging technique to see which method works better for patients in the intensive care unit.
SanliurfaAges 18 years+ - NCT02539407Recruiting
Study drug levels in critically ill children
This trial measures how anti-infective medicines move through a child’s body while they are in the hospital or during follow-up. The goal is to better understand dosing and drug exposure in critically ill children.
ParisAges 1 day–18 years - NCT07519512Recruiting
Early Switch to Assisted Breathing in ICU Patients
This study tests whether moving ICU patients from fully machine-controlled breathing to partially assisted breathing earlier helps them get off ventilators successfully. The goal is to see if this approach reduces the time patients need mechanical ventilation.
Nanjing, JiangsuAges 18 years+ - NCT07339397Recruiting
Joint stiffness in ICU patients on breathing machines
This trial studies how common joint stiffness becomes in ICU patients who are on a breathing machine and cannot move for at least 7 days. It may help doctors better prevent and treat this problem.
Elâzığ, ElaziğAges 18 years+ - NCT07220733RecruitingPhase 1/Phase 2
Exoskeleton rehab after chest surgery in the ICU
This trial tests whether a self-balancing exoskeleton can help people who had chest surgery and are weak (bedbound or nearly so) start walking earlier in the ICU. It aims to see if it is safe and possible to use this device for rehabilitation.
Boston, MassachusettsAges 18 years+ - NCT06999161Recruiting
Tracking Antibiotic Levels in ICU Brain Injury Patients
This study monitors the amount of certain antibiotics in the blood of patients with acute brain injury in the intensive care unit. It aims to make sure the antibiotics are at the right level to fight infection, especially in patients whose kidneys are clearing drugs faster than normal.
NîmesAges 18 years+ - NCT07074028Recruiting
Tracking muscle changes in ICU patients with sepsis
This study is for people in the ICU with sepsis who need a breathing machine for a long time. It monitors muscle changes during recovery to understand how sepsis affects muscles.
Saint-BrieucAges 18 years+ - NCT06814457Recruiting
Nursing care bundle for swallowing after breathing tube removal in children
This trial tests a special nursing care plan to help children who had a breathing tube eat and drink safely after it's removed. It aims to reduce swallowing problems in the intensive care unit.
Kafr ash Shaykh, Kafr Ash Shaykh, Kafr el-Sheikh, Egypt,Ages 6–18 - NCT07170527Recruiting
Metabolic signs, recovery, and physical function after ICU stay
This study looks at whether certain molecules in the blood (metabolic signatures) are linked to how well people recover physically after a serious illness requiring intensive care. By understanding these links, doctors might be able to better predict and support recovery.
Ede, GelderlandAges 18 years+ - NCT05867472RecruitingPhase 3
Sedation plan for critically ill children on breathing machines
This Phase 3 trial tests a sedation approach using inhaled (“volatile”) anesthesia gases for children who need a ventilator. It aims to improve comfort and brain-related outcomes while they stay on the breathing machine for at least a day.
Hamilton, OntarioAges 1 month–18 years - NCT05860894Recruiting
Study of new ICU atrial fibrillation
This trial looks at people who develop a new irregular heart rhythm called atrial fibrillation while in the intensive care unit (ICU). It tests an approach to help with that condition after critical illness, aiming to improve outcomes for those affected.
BesançonAges 18 years+ - NCT06296381Recruiting
Measuring normal muscle strength in ICU patients and healthy people
This study measures normal muscle strength in healthy people and ICU patients to create a reference guide. If you are healthy or in the ICU and can follow instructions, you may be able to help.
Recife, BrazilAges 18–90 - NCT06478160Recruiting
Closed blood-sampling system for ICU patients
This trial is testing a new way to draw blood from an arterial line that may reduce infection and blood loss. It is for adults in the ICU who need an arterial line for several days.
Madrid, MadridAges 18 years+ - NCT07694206Recruiting
Digital and blood tests for delirium in the ICU
This trial studies whether digital tools and blood tests can help detect delirium (sudden confusion) in ICU patients. If you or your loved one is in the ICU, this research could lead to better monitoring and care.
La Jolla, CaliforniaAges 65 years+ - NCT06665529Recruiting
Predicting 28-day survival in the ICU
This trial looks at how doctors and nurses predict survival for critically ill patients in the intensive care unit, compared to a standard medical score. It may help understand the accuracy of these predictions.
Kfar SabaAges 18–99 - NCT06117345Enrolling by invitation
PICU Journal for Parents and Caregivers
This study tests a journal to help parents and caregivers stay involved while their child is in the pediatric intensive care unit (PICU). It aims to see if the journal improves communication and engagement.
Nashville, TennesseeAges 18 years+ - NCT07649876Recruiting
Virtual Reality to Reduce Anxiety in Critically Ill Patients
This study tests whether wearing a virtual reality headset—which shows calming scenes like nature—can help reduce anxiety, agitation, and confusion in patients admitted to the intensive care unit. The goal is to see if VR can help patients feel more comfortable during their recovery.
Hershey, PennsylvaniaAges Any age
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Common questions
- Are there clinical trials for critical care?
- Yes. Clin2 currently lists 188 recruiting critical care studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a critical care trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a critical care trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.