Clinical trials
Critical Care clinical trials
Below are recruiting critical care clinical trials, each written for real people, not researchers. We’re tracking 183 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06526533RecruitingPhase 3
Red blood cell transfusion thresholds for ECMO patients
This trial is testing whether a higher or lower threshold for red blood cell transfusions is better for people on ECMO (a heart-lung machine). It aims to find the safest way to manage transfusions during ECMO treatment.
Camperdown, New South WalesAges Any age - NCT06961227Recruiting
Comparing two breathing machine settings in the ICU
This trial compares two different ways a breathing machine can help you breathe. It uses a special imaging technique to see which method works better for patients in the intensive care unit.
SanliurfaAges 18 years+ - NCT07519512Recruiting
Early Switch to Assisted Breathing in ICU Patients
This study tests whether moving ICU patients from fully machine-controlled breathing to partially assisted breathing earlier helps them get off ventilators successfully. The goal is to see if this approach reduces the time patients need mechanical ventilation.
Nanjing, JiangsuAges 18 years+ - NCT07220733RecruitingPhase 1/Phase 2
Exoskeleton rehab after chest surgery in the ICU
This trial tests whether a self-balancing exoskeleton can help people who had chest surgery and are weak (bedbound or nearly so) start walking earlier in the ICU. It aims to see if it is safe and possible to use this device for rehabilitation.
Boston, MassachusettsAges 18 years+ - NCT07074028Recruiting
Tracking muscle changes in ICU patients with sepsis
This study is for people in the ICU with sepsis who need a breathing machine for a long time. It monitors muscle changes during recovery to understand how sepsis affects muscles.
Saint-BrieucAges 18 years+ - NCT06999161Recruiting
Tracking Antibiotic Levels in ICU Brain Injury Patients
This study monitors the amount of certain antibiotics in the blood of patients with acute brain injury in the intensive care unit. It aims to make sure the antibiotics are at the right level to fight infection, especially in patients whose kidneys are clearing drugs faster than normal.
NîmesAges 18 years+ - NCT02539407Recruiting
Study drug levels in critically ill children
This trial measures how anti-infective medicines move through a child’s body while they are in the hospital or during follow-up. The goal is to better understand dosing and drug exposure in critically ill children.
ParisAges 1 day–18 years - NCT06814457Recruiting
Nursing care bundle for swallowing after breathing tube removal in children
This trial tests a special nursing care plan to help children who had a breathing tube eat and drink safely after it's removed. It aims to reduce swallowing problems in the intensive care unit.
Kafr ash Shaykh, Kafr Ash Shaykh, Kafr el-Sheikh, Egypt,Ages 6–18 - NCT07170527Recruiting
Metabolic signs, recovery, and physical function after ICU stay
This study looks at whether certain molecules in the blood (metabolic signatures) are linked to how well people recover physically after a serious illness requiring intensive care. By understanding these links, doctors might be able to better predict and support recovery.
Ede, GelderlandAges 18 years+ - NCT05867472RecruitingPhase 3
Sedation plan for critically ill children on breathing machines
This Phase 3 trial tests a sedation approach using inhaled (“volatile”) anesthesia gases for children who need a ventilator. It aims to improve comfort and brain-related outcomes while they stay on the breathing machine for at least a day.
Hamilton, OntarioAges 1 month–18 years - NCT05860894Recruiting
Study of new ICU atrial fibrillation
This trial looks at people who develop a new irregular heart rhythm called atrial fibrillation while in the intensive care unit (ICU). It tests an approach to help with that condition after critical illness, aiming to improve outcomes for those affected.
BesançonAges 18 years+ - NCT07694206Recruiting
Digital and blood tests for delirium in the ICU
This trial studies whether digital tools and blood tests can help detect delirium (sudden confusion) in ICU patients. If you or your loved one is in the ICU, this research could lead to better monitoring and care.
La Jolla, CaliforniaAges 65 years+ - NCT06478160Recruiting
Closed blood-sampling system for ICU patients
This trial is testing a new way to draw blood from an arterial line that may reduce infection and blood loss. It is for adults in the ICU who need an arterial line for several days.
Madrid, MadridAges 18 years+ - NCT06296381Recruiting
Measuring normal muscle strength in ICU patients and healthy people
This study measures normal muscle strength in healthy people and ICU patients to create a reference guide. If you are healthy or in the ICU and can follow instructions, you may be able to help.
Recife, BrazilAges 18–90 - NCT06117345Enrolling by invitation
PICU Journal for Parents and Caregivers
This study tests a journal to help parents and caregivers stay involved while their child is in the pediatric intensive care unit (PICU). It aims to see if the journal improves communication and engagement.
Nashville, TennesseeAges 18 years+ - NCT07649876Recruiting
Virtual Reality to Reduce Anxiety in Critically Ill Patients
This study tests whether wearing a virtual reality headset—which shows calming scenes like nature—can help reduce anxiety, agitation, and confusion in patients admitted to the intensive care unit. The goal is to see if VR can help patients feel more comfortable during their recovery.
Hershey, PennsylvaniaAges Any age - NCT06171919Recruiting
Legal help for people with HIV after incarceration
This study provides legal support to improve HIV care for people who have recently been released from jail or prison. It helps them stay in treatment and lower their viral load.
Orlando, FloridaAges 18–100 - NCT07761364Recruiting
Contact with family in the intensive care unit
This study looks at how a visit from your main family caregiver affects your body while you are in the intensive care unit (ICU). It aims to see if having that personal contact can help you feel better and recover.
Mexico City, Mexico CityAges 18–59 - NCT07642076RecruitingPhase 4
L-carnitine supplement for critically ill liver disease patients
This study tests whether adding L-carnitine (a naturally occurring compound) to standard care helps people with serious liver disease who are in the intensive care unit. L-carnitine may help the body use energy better and reduce complications from liver failure.
Shibīn al KawmAges 18 years+ - NCT07094425Recruiting
Heart function study for ICU patients on breathing machines
This study looks at how the heart is affected in critically ill patients who need a breathing machine. It uses ultrasound and other simple tests to check for heart problems that can happen in the ICU, which may help doctors find and treat them earlier.
Vienna, State of ViennaAges 18 years+ - NCT05541029Recruiting
Music listening for children on breathing machines
This study tests whether listening to music can help children who are in the Pediatric Intensive Care Unit (PICU) and need a breathing machine. It looks at the “how it works” side—whether music changes things in the body or brain during intensive care.
Pittsburgh, PennsylvaniaAges 2 months–17 years - NCT07496255Recruiting
Virtual reality for memory help after ICU confusion
This trial tests whether using virtual reality (VR) can help older adults recover their thinking and memory after a serious illness and confusion in the ICU. You may be eligible if you are 50 or older, spent time on a breathing machine, and had delirium in the ICU.
Indianapolis, IndianaAges 50 years+ - NCT07254299Recruiting
Hypnosis for ICU recovery and wellbeing
This study tests whether hypnosis sessions during an ICU stay can improve mental and physical recovery after a serious illness. It aims to reduce long-term problems like anxiety, depression, and memory issues.
GenevaAges 18 years+ - NCT07562048Recruiting
Comfort Cuddling for Children in Critical Care
This study looks at whether gentle cuddling and physical comfort help children feel better while they're in the intensive care unit. Researchers believe close contact with caregivers may reduce stress and improve how children recover.
Calgary, AlbertaAges Up to 18 years
Hear when a new Critical Care trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for critical care?
- Yes. Clin2 currently lists 183 recruiting critical care studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a critical care trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a critical care trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.