Clinical trials
Critically Ill clinical trials
Below are recruiting critically ill clinical trials, each written for real people, not researchers. We’re tracking 352 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05359601Recruiting
Testing how often to change infusion tubing in ICU
This trial compares timing for replacing the IV infusion tubing in critically ill ICU patients. It may help reduce infection risk while avoiding unnecessary changes by finding an interval that is safe and practical.
Wuhan, HubeiAges 18 years+ - NCT06576895Recruiting
Nutrition study in critically ill adults
This study looks at how nutrition is given to adults in the intensive care unit (ICU). It aims to understand current practices and may help improve care for future patients.
Melbourne, VictoriaAges 18 years+ - NCT06786390Recruiting
Walking recovery after muscle weakness
This trial tests if a walking program combined with electrical stimulation can help people recover walking ability after critical illness. It is for patients who developed limb weakness in the hospital and were independent before their illness.
MilanAges 18–85 - NCT07032870Recruiting
Ultrasound reliability study in ICU patients
This study checks how reliably different physical therapists can measure muscles and nerves using ultrasound in patients who are awake and stable in the intensive care unit (ICU). It aims to improve muscle assessment techniques for critically ill adults.
Santiago, Metropolitan RegionAges 18 years+ - NCT07173504Recruiting
Continuous vs. intermittent tube feeding in ICU patients
This trial compares giving tube feeding continuously versus taking breaks to see which approach helps critically ill patients' metabolism better. It is for adults in the ICU who need a breathing tube and will be fed through a stomach tube.
Ede, GelderlandAges 18 years+ - NCT07173855RecruitingPhase 4
Magnesium replacement in ICU patients
This trial tests whether giving magnesium as part of a standard hospital protocol can lower the risk of irregular heartbeat and improve survival in patients admitted to the intensive care unit.
Ajax, OntarioAges 16 years+ - NCT07222007Recruiting
Induction agent choice and survival in ICU patients
This study looks at how the type of medicine used to start sedation in the surgical ICU affects early survival and recovery. It may help doctors choose safer options for critically ill patients.
Jacksonville, FloridaAges 18 years+ - NCT07301970Recruiting
Remifentanil dosing in low-weight ICU patients
This study looks at how the sedative remifentanil works in critically ill patients who are underweight or normal weight. It aims to find the right dose for these patients while they are on a breathing machine in the ICU.
ShanghaiAges Any age - NCT07372586Recruiting
Behavioral health support after ICU stay
This study tests a collaborative care model for mental health and recovery after an ICU stay. You might qualify if you visit the MUSC ICU Recovery Clinic within six months of leaving the hospital.
Charleston, South CarolinaAges 18 years+ - NCT04580680Recruiting
Testing a blood-filter treatment in critically ill ICU patients
This study looks at an add-on blood-filter treatment used in the ICU to help remove harmful substances like waste products, inflammation signals, or toxins from the blood. Results may help doctors understand whether this approach improves care and how it should be used.
FlorenceAges Any age - NCT06220825Recruiting
Breathing support practices in critically ill children
This trial looks at how doctors manage breathing support for children in the intensive care unit. It may help improve care for kids who need help breathing.
GroningenAges Up to 18 years - NCT06923462Recruiting
VoiceLove app for ICU patients on a ventilator
This study tests a special app called VoiceLove that helps patients in the ICU who are on a breathing machine communicate with their family and care team. The goal is to reduce confusion and improve connection and satisfaction for everyone involved.
Nashville, TennesseeAges 18 years+ - NCT05850962Recruiting
Personalized blood pressure targets for ICU shock care
This study compares individualized blood pressure goals versus the usual (standard) targets for adults in the ICU with shock. The aim is to see whether tailored blood pressure treatment can improve outcomes by better matching each person’s needs.
Newcastle, New South WalesAges 40 years+ - NCT07001943Recruiting
Blood flow in stomach and gut injury in ICU patients
This trial checks if changes in blood flow to the stomach and intestines can predict gut injury in critically ill patients who need feeding through a tube. It uses a safe ultrasound test at the bedside.
Beijing, Beijing MunicipalityAges 18–80 - NCT06453421Recruiting
Breathing and exercise rehab for long-term breathing machine patients
This study tests a special breathing and exercise program for people who have been on a breathing machine for a long time through a tracheostomy. The program is designed to help them get stronger and breathe better.
FlorenceAges 18 years+ - NCT07430969Recruiting
Muscle Stimulation and Amino Acids for ICU Patients on Ventilators
This trial tests whether giving muscle stimulation and amino acids can help patients in the ICU who are on a breathing machine to maintain their muscle protein. The study aims to prevent muscle wasting during critical illness.
EdeAges 18 years+ - NCT04502511Recruiting
Study of different patterns of critical illness in ICU patients
This study looks at how critical illness can vary from person to person in the intensive care unit (ICU). It mainly helps researchers understand these differences and may improve future care for ICU patients.
Groningen, Provincie GroningenAges 18 years+ - NCT05993390Recruiting
Reversing muscle relaxants in ICU patients
This trial tests two medicines that help reverse the muscle-relaxing drugs given to patients on breathing tubes in the intensive care unit. The goal is to see which one works better and faster so patients can wake up sooner.
Seoul, Jongno-guAges 19–90 - NCT06950294RecruitingEarly Phase 1
Inhaled nitric oxide for pneumonia patients on a ventilator
This study tests an inhaled gas (iNO300) given through your breathing tube to improve oxygen levels in critically ill patients with pneumonia. You may qualify if you are on a ventilator and have been diagnosed with pneumonia within the last 3 days.
Boston, MassachusettsAges 18 years+ - NCT07001696Recruiting
Predicting breathing support needs with chest X-ray and blood gas
This trial looks at whether combining a chest X-ray and a blood gas test can help doctors decide if a critically ill patient needs a breathing machine (mechanical ventilation). It aims to find a better way to make this important decision.
Zagazig, Al SharqiaAges 18 years+ - NCT07189091RecruitingPhase 4
Reducing IV fluids in ICU patients
This trial tests if lowering the amount of salt water (sodium chloride) given as maintenance fluids or 'fluid creep' can help critically ill adults in the ICU recover better. It compares two ways of managing daily fluids to see which is safer and more effective.
AntwerpAges 18 years+ - NCT06762184Recruiting
Pain scores in serious brain surgery patients after ICU care
This study looks back at patients who had brain surgery and were in the intensive care unit (ICU) for more than 24 hours. Researchers want to learn about their pain scores, which can help improve care for future patients.
Beijing, BeijingAges 18 years+ - NCT04404400RecruitingPhase 3
Hydrocortisone and fludrocortisone for critical illness hormone shortage
This Phase 3 trial tests whether giving hydrocortisone plus fludrocortisone to critically ill ICU patients with suspected “corticosteroid insufficiency” can improve outcomes without relying on steroids already being used. It may help patients whose bodies aren’t making enough stress hormones during severe illness.
GarchesAges 18 years+ - NCT05055830Recruiting
Study blood drug levels in critically ill children
This trial measures how the study medicines move through the body and how they affect the child in the Pediatric Cardiac Intensive Care Unit. It may help doctors choose safer and better dosing for critically ill children.
Durham, North CarolinaAges birth–20 years
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Common questions
- Are there clinical trials for critically ill?
- Yes. Clin2 currently lists 352 recruiting critically ill studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a critically ill trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a critically ill trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.