Clinical trials
Deep Brain Stimulation clinical trials
Below are recruiting deep brain stimulation clinical trials, each written for real people, not researchers. We’re tracking 193 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06891781Recruiting
Adaptive deep brain stimulation for Parkinson's
This study tests a new type of deep brain stimulation (DBS) that adapts to your brain activity in real time. It is for people with Parkinson's disease whose symptoms are not well managed by medication and who are already candidates for DBS surgery.
MonzaAges 18 years+ - NCT06813300Recruiting
Brain signals during deep brain stimulation for thinking or moving tasks
This study looks at how brain signals change during deep brain stimulation (DBS) when you are thinking or moving. It aims to find better ways to see if DBS is working by recording your brain's electrical activity.
GrenobleAges 18 years+ - NCT05843084Recruiting
7-Tesla brain scans to map networks for Parkinson’s DBS
This study uses a very strong MRI (7-tesla) to analyze how parts of the brain connect in people with Parkinson’s who already have deep brain stimulation (DBS). It may help researchers better understand DBS and how it works in the brain.
Amsterdam, North HollandAges 18 years+ - NCT06685510Enrolling by invitation
Deep brain stimulation outcomes and electrode position in Parkinson's
This study looks at how the placement of electrodes during deep brain stimulation (DBS) for Parkinson's disease affects recovery and motor symptoms right after surgery. It could help doctors improve DBS outcomes for people with Parkinson's.
Nanchang, JiangxiAges 18–75 - NCT06660225Recruiting
Deep brain stimulation for severe OCD
This trial tests if deep brain stimulation (a surgical treatment that uses electrical pulses to adjust brain activity) can help people with severe obsessive-compulsive disorder (OCD) that has not improved with other treatments. It is for adults aged 22 to 75 who have had OCD symptoms for over 5 years.
Dallas, TexasAges 22–75 - NCT06618157Enrolling by invitation
Brain stimulation study for Parkinson's tremor
This study tests a new way to adjust deep brain stimulation (DBS) for Parkinson's disease. It focuses on people who still have at least mild tremor after their DBS device has been in place for three months or more, to see if targeting specific brain connections can help improve tremor control.
Durham, North CarolinaAges 18 years+ - NCT06585618Recruiting
Pediatric Deep Brain Stimulation Registry
This study creates a list of children who already have or plan to get Deep Brain Stimulation (DBS) to see how it helps with movement problems. Joining helps doctors learn more about how DBS works in kids.
Boston, MassachusettsAges birth–18 years - NCT06578429Recruiting
Deep TMS for methamphetamine use disorder
This study uses a type of brain stimulation called deep TMS to see if it can help people with methamphetamine use disorder reduce their cravings and use. You would receive daily magnetic pulses to specific brain areas over several weeks.
Palo Alto, CaliforniaAges 25–75 - NCT06524505Recruiting
Deep brain stimulation for bipolar depression
This trial tests a non-invasive brain stimulation technique called deep transcranial magnetic stimulation (dTMS) to see if it improves depression in people with bipolar disorder. dTMS uses magnetic pulses to stimulate brain areas involved in mood regulation.
TianjinAges 18–65 - NCT06303869Recruiting
Deep brain stimulation for speech after stroke
This study tests if deep brain stimulation (a small device implanted in the brain) can improve speech and arm movement after a stroke that affected the deeper parts of the brain. It is designed for people who have trouble speaking clearly (dysarthria) from their stroke.
Pittsburgh, PennsylvaniaAges 18–75 - NCT06257056Recruiting
Deep brain stimulation for hard-to-treat schizophrenia
This trial tests whether deep brain stimulation (a device that sends electrical pulses to specific areas of the brain) can help people with schizophrenia whose symptoms have not improved with standard treatments. If you have ongoing psychosis and have tried several medications without success, this study may be an option for you.
Dallas, TexasAges 22–70 - NCT06112067Recruiting
Brain implant for severe mental health conditions
This trial tests a brain implant called deep brain stimulation (DBS) for people with severe mental health conditions that have not improved with usual treatments. The goal is to see if it can reduce symptoms and improve quality of life.
ShanghaiAges 18–65 - NCT05962489Recruiting
Sleep-focused DBS therapy study for Parkinson’s disease
This study looks at a sleep-focused approach to brain stimulation (DBS) in people with Parkinson’s disease. You may be able to join if you’re planning or scheduled for specific DBS surgery at the University of Minnesota and have the needed brain imaging.
Minneapolis, MinnesotaAges 21 years+ - NCT05893186RecruitingEarly Phase 1
Testing DBS settings for walking and balance in Parkinson’s
This early-phase study looks at whether adjusting deep brain stimulation (DBS) can improve posture, walking, and balance in people with Parkinson’s disease. If you already have DBS in place, the trial uses computer-based planning to try different DBS directions and settings to see what helps you most.
Minneapolis, MinnesotaAges 18–89 - NCT05897775RecruitingPhase 1
Testing a new deep brain stimulator approach for essential tremor
This Phase 1 study tests a coordinated reset deep brain stimulation program for people with essential tremor. It may help reduce tremor symptoms using a specific implanted brain-stimulation device, along with special high-strength MRI and CT imaging before and after surgery.
Minneapolis, MinnesotaAges 21 years+ - NCT05822388Recruiting
Deep brain stimulation and memory changes in Parkinson’s
This study looks at whether deep brain stimulation (a surgical treatment for Parkinson’s disease) affects thinking and memory over time. It compares Parkinson’s participants to people without Parkinson’s to better understand what changes happen with treatment.
Charleston, South CarolinaAges 18 years+ - NCT05150093Recruiting
Deep brain stimulation for voice tremor or dystonia
This trial studies deep brain stimulation (a surgically placed device that sends electrical signals) to reduce voice tremor or laryngeal dystonia. You may be considered if your symptoms are persistent despite medication and you can complete the study tasks and pre-surgery testing.
Boston, MassachusettsAges 18–80 - NCT05557864Recruiting
Brain scan study for Parkinson’s patients with deep brain stimulators
This study looks at how the location of a deep brain stimulator in Parkinson’s disease affects movement problems. It mainly uses advanced 7T brain imaging to compare brain activity and motor symptoms.
Minneapolis, MinnesotaAges 21–89 - NCT05506085Recruiting
Brain stimulator study for voice spasms with tremor
This trial studies a brain stimulation approach for a specific voice disorder that can include tremor. It aims to better understand how well the treatment works and how to use it more effectively while carefully checking safety with awake procedures.
Indianapolis, IndianaAges 18–70 - NCT05493722RecruitingEarly Phase 1
Adjusting deep brain stimulator settings for hard-to-control seizures
This early-phase study tests whether changing your deep brain stimulator settings can improve seizure control in people whose epilepsy is not helped by usual treatments. It is mainly for patients who already have the stimulator placed.
Minneapolis, MinnesotaAges 18 years+ - NCT05065151Recruiting
Studying motivation in Parkinson’s using brain stimulation recordings
This study looks at what drives motivation in people with Parkinson’s disease (or dystonia) by using recordings from an implanted brain stimulation device. It may help researchers understand brain signals behind motivation and improve future treatments.
San Francisco, CaliforniaAges 18 years+ - NCT04758624Recruiting
Study brain changes after deep brain stimulation for tremor
This study looks at how brain “wiring” (connectivity) and brain function change over time in people with essential tremor after successful deep brain stimulation. You might benefit by helping researchers better understand what DBS does in the brain, which can improve care for others with tremor.
Manhasset, New YorkAges 18–85 - NCT04605263Enrolling by invitation
Deep brain stimulation for Parkinson’s walking and falls
This study tests a brain surgery treatment (deep brain stimulation) to help improve gait problems such as freezing of walking, gait instability, or falls in people with Parkinson’s disease. It may help people whose walking symptoms are not well controlled by levodopa (a common Parkinson’s medicine).
Phoenix, ArizonaAges 18–75 - NCT04449068Recruiting
Tourette research using records from deep brain stimulation patients
This study is collecting information about people with severe Tourette syndrome who are not adequately helped by medication and may receive deep brain stimulation. It helps researchers understand outcomes and care patterns for this treatment over time using an observational database.
ParisAges 15 years+
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Common questions
- Are there clinical trials for deep brain stimulation?
- Yes. Clin2 currently lists 193 recruiting deep brain stimulation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a deep brain stimulation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a deep brain stimulation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.