Clinical trials
Deep Brain Stimulation clinical trials
Below are recruiting deep brain stimulation clinical trials, each written for real people, not researchers. We’re tracking 208 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05822388Recruiting
Deep brain stimulation and memory changes in Parkinson’s
This study looks at whether deep brain stimulation (a surgical treatment for Parkinson’s disease) affects thinking and memory over time. It compares Parkinson’s participants to people without Parkinson’s to better understand what changes happen with treatment.
Charleston, South CarolinaAges 18 years+ - NCT05843084Recruiting
7-Tesla brain scans to map networks for Parkinson’s DBS
This study uses a very strong MRI (7-tesla) to analyze how parts of the brain connect in people with Parkinson’s who already have deep brain stimulation (DBS). It may help researchers better understand DBS and how it works in the brain.
Amsterdam, North HollandAges 18 years+ - NCT05893186RecruitingEarly Phase 1
Testing DBS settings for walking and balance in Parkinson’s
This early-phase study looks at whether adjusting deep brain stimulation (DBS) can improve posture, walking, and balance in people with Parkinson’s disease. If you already have DBS in place, the trial uses computer-based planning to try different DBS directions and settings to see what helps you most.
Minneapolis, MinnesotaAges 18–89 - NCT05897775RecruitingPhase 1
Testing a new deep brain stimulator approach for essential tremor
This Phase 1 study tests a coordinated reset deep brain stimulation program for people with essential tremor. It may help reduce tremor symptoms using a specific implanted brain-stimulation device, along with special high-strength MRI and CT imaging before and after surgery.
Minneapolis, MinnesotaAges 21 years+ - NCT05909839Recruiting
7-Tesla brain MRI network study for deep brain stimulation tremor
This study looks at detailed brain imaging using a very strong MRI (7-Tesla) to understand brain network changes after deep brain stimulation for essential tremor. It may help improve how DBS works and how tremor can be better treated in the future.
Amsterdam, North HollandAges 18 years+ - NCT05962489Recruiting
Sleep-focused DBS therapy study for Parkinson’s disease
This study looks at a sleep-focused approach to brain stimulation (DBS) in people with Parkinson’s disease. You may be able to join if you’re planning or scheduled for specific DBS surgery at the University of Minnesota and have the needed brain imaging.
Minneapolis, MinnesotaAges 21 years+ - NCT05995951Recruiting
Deep brain stimulation for severe OCD
This trial tests whether deep brain stimulation (a surgical implant that sends electrical pulses to part of your brain) can help people with severe obsessive-compulsive disorder (OCD) that has not improved with standard treatments.
Petah TikvaAges 18–75 - NCT06090682Recruiting
Brain stimulation for Parkinson's with thinking problems
This trial tests a brain stimulation technique (deep brain stimulation) to see if it can help people with Parkinson's disease who also have mild cognitive problems. The goal is to understand how stimulation affects both movement and thinking.
Tianjin, Tianjin MunicipalityAges Up to 75 years - NCT06257056Recruiting
Deep brain stimulation for hard-to-treat schizophrenia
This trial tests whether deep brain stimulation (a device that sends electrical pulses to specific areas of the brain) can help people with schizophrenia whose symptoms have not improved with standard treatments. If you have ongoing psychosis and have tried several medications without success, this study may be an option for you.
Dallas, TexasAges 22–70 - NCT06303960RecruitingEarly Phase 1
Brain stimulation for chronic stroke arm recovery
This early-phase trial tests whether brain stimulation (deep brain stimulation in the cerebellum or vagus nerve stimulation) can help improve arm and hand movement in people who had a stroke 1 to 3 years ago.
Jinan, ShandongAges 30–75 - NCT06303869Recruiting
Deep brain stimulation for speech after stroke
This study tests if deep brain stimulation (a small device implanted in the brain) can improve speech and arm movement after a stroke that affected the deeper parts of the brain. It is designed for people who have trouble speaking clearly (dysarthria) from their stroke.
Pittsburgh, PennsylvaniaAges 18–75 - NCT07049003RecruitingPhase 1
Deep brain stimulation for severe tremor
This trial tests a new type of deep brain stimulation (DBS) for people with severe tremor from essential tremor, multiple sclerosis, or cerebellar conditions who haven't improved with standard treatments. It targets a different brain area to see if it can reduce shaking and improve daily activities.
Cleveland, OhioAges 21 years+ - NCT06400901Recruiting
Brain signals during recovery from anesthesia for DBS patients
This trial records brain activity during recovery from general anesthesia in people undergoing deep brain stimulation (DBS) surgery. It aims to understand how the brain wakes up after anesthesia.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06446505Recruiting
Decision aid for deep brain stimulation in Parkinson's
This study tests a decision aid to help people with Parkinson's disease who are being considered for deep brain stimulation (DBS) surgery. The goal is to see if the tool helps patients make more informed choices about their treatment.
Aurora, ColoradoAges 18 years+ - NCT06480188Recruiting
Comparing two brain stimulation targets for craniocervical dystonia
This trial tests how deep brain stimulation (DBS) works when targeting two different brain areas (STN or GPi) for people with craniocervical dystonia. It aims to find which target better helps symptoms and why.
Hefei, AnhuiAges 18–75 - NCT06524505Recruiting
Deep brain stimulation for bipolar depression
This trial tests a non-invasive brain stimulation technique called deep transcranial magnetic stimulation (dTMS) to see if it improves depression in people with bipolar disorder. dTMS uses magnetic pulses to stimulate brain areas involved in mood regulation.
TianjinAges 18–65 - NCT06542224Recruiting
Finding Brain Signals to Guide OCD Deep Brain Stimulation
This study is testing whether brain signals measured during deep brain stimulation (DBS) can help doctors better treat Obsessive-Compulsive Disorder. It may offer a new way to personalize treatment for people with severe, treatment-resistant OCD.
Chengdu, SichuanAges 18–65 - NCT06542094Recruiting
Brain stimulation for severe depression that hasn't improved with other treatments
This trial tests if deep brain stimulation (a device that sends tiny electrical pulses to mood-related brain areas) can help people with tough-to-treat depression. It uses brain-signal monitoring to see which patterns predict improvement.
Chengdu, SichuanAges 18–65 - NCT06543563Recruiting
Esketamine for anesthesia during Parkinson's brain surgery
This trial is testing whether a drug called esketamine (related to ketamine) can help make the anesthesia experience better for people with Parkinson's disease who are undergoing a specific brain surgery called bilateral STN-DBS. If you qualify, you would receive esketamine during your procedure to see if it improves outcomes.
Beijing, Beijing MunicipalityAges 50–80 - NCT06585618Recruiting
Pediatric Deep Brain Stimulation Registry
This study creates a list of children who already have or plan to get Deep Brain Stimulation (DBS) to see how it helps with movement problems. Joining helps doctors learn more about how DBS works in kids.
Boston, MassachusettsAges birth–18 years - NCT06628752Recruiting
Deep brain stimulation for severe OCD
This study tests a treatment called deep brain stimulation (DBS) for people with severe OCD that hasn't improved with standard therapies. DBS uses a device to send small electrical pulses to specific parts of the brain to help control symptoms.
Umeå, Västerbotten CountyAges 18–65 - NCT06660225Recruiting
Deep brain stimulation for severe OCD
This trial tests if deep brain stimulation (a surgical treatment that uses electrical pulses to adjust brain activity) can help people with severe obsessive-compulsive disorder (OCD) that has not improved with other treatments. It is for adults aged 22 to 75 who have had OCD symptoms for over 5 years.
Dallas, TexasAges 22–75 - NCT06705296RecruitingPhase 1
Deep brain stimulation for severe PTSD
This trial tests whether deep brain stimulation, a surgery that uses a small device to send electrical pulses to specific brain areas, can help people with severe PTSD that hasn't improved after trying several treatments. It aims to see if this approach is safe and effective for long-lasting symptoms.
Toronto, OntarioAges 18–70 - NCT02071134Recruiting
Registry study for Vercise deep brain stimulation patients
This study keeps a record of people who receive the Vercise deep brain stimulation system. It helps doctors learn how the treatment is used in real-world care and how patients do over time.
Aliso Viejo, CaliforniaAges 18 years+
Hear when a new Deep Brain Stimulation trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for deep brain stimulation?
- Yes. Clin2 currently lists 208 recruiting deep brain stimulation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a deep brain stimulation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a deep brain stimulation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.