Clinical trials
Deep Brain Stimulation clinical trials
Below are recruiting deep brain stimulation clinical trials, each written for real people, not researchers. We’re tracking 193 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07214467Recruiting
Adaptive brain stimulation for opioid use disorder
This study tests a new type of brain stimulation that adapts to your brain activity, aiming to reduce cravings and help you control opioid use. It is for people with long-standing opioid use disorder who have not gotten lasting relief from at least 3 treatment attempts, including medication.
San Francisco, CaliforniaAges 22–75 - NCT05909839Recruiting
7-Tesla brain MRI network study for deep brain stimulation tremor
This study looks at detailed brain imaging using a very strong MRI (7-Tesla) to understand brain network changes after deep brain stimulation for essential tremor. It may help improve how DBS works and how tremor can be better treated in the future.
Amsterdam, North HollandAges 18 years+ - NCT06303960RecruitingEarly Phase 1
Brain stimulation for chronic stroke arm recovery
This early-phase trial tests whether brain stimulation (deep brain stimulation in the cerebellum or vagus nerve stimulation) can help improve arm and hand movement in people who had a stroke 1 to 3 years ago.
Jinan, ShandongAges 30–75 - NCT06932692Recruiting
Brain network analysis using 7-Tesla MRI in DBS patients
This study uses advanced brain imaging (7-Tesla MRI and MEG) to understand how deep brain stimulation (DBS) affects brain networks in people with Parkinson's disease or essential tremor. It helps doctors learn how DBS works so they can improve treatment in the future.
Amsterdam, North HollandAges 18 years+ - NCT05416905Recruiting
Deep brain stimulation for facial dystonia using GPi or STN
This trial studies deep brain stimulation (a surgically placed device that sends targeted electrical signals) to treat idiopathic craniofacial dystonia when medicines or botulinum toxin haven’t helped enough. It compares stimulating two brain targets (GPi versus STN) to see which approach may improve symptoms.
BeijingAges 18–75 - NCT07187739Recruiting
Mediterranean diet for Parkinson's with deep brain stimulation
This study tests whether a Mediterranean diet can improve nutrition in people with Parkinson's disease who have had deep brain stimulation surgery. It may help you maintain better nutrition and overall health.
Ankara, AnkaraAges 45–64 - NCT07190092Recruiting
Brain stimulation for post-stroke muscle stiffness and movement
This study tests a new type of brain stimulation (deep anterior cerebellar stimulation) to see if it can reduce muscle stiffness and improve movement in people who had a stroke 9–36 months ago and still have tightness or weakness that hasn't gotten better with therapy.
BydgoszczAges 18 years+ - NCT07176494Recruiting
Revision of Deep Brain Stimulator in Parkinson's Disease
This study is for people with Parkinson's disease who need to have their deep brain stimulator (a device that sends electrical pulses to control movement) replaced or adjusted. The researchers want to learn the best way to do this procedure safely.
Ankara, Yenimahalle\AnkaraAges 40–85 - NCT06936124Recruiting
Deep brain stimulation for Alzheimer's disease
This trial tests whether deep brain stimulation of a specific brain area can help people with Alzheimer's disease. It aims to see if this treatment can improve symptoms and quality of life.
Toronto, OntarioAges 60 years+ - NCT07110376Recruiting
Brain recordings during sleep with deep brain stimulation for Parkinson's
This study looks at brain activity during sleep in people with Parkinson's who have a deep brain stimulation (DBS) device. It aims to understand how different DBS settings affect sleep, which may help improve treatment.
Cleveland, OhioAges 18 years+ - NCT07109804Recruiting
Deep brain stimulation to improve walking after spinal cord injury
This study tests whether stimulating a small area deep in the brain (the cuneiform nucleus) with a device called deep brain stimulation (DBS) can help people walk better after a spinal cord injury. The goal is to see if it improves walking speed and stability.
Miami, FloridaAges 22–70 - NCT07094438RecruitingPhase 1
Brain stimulation and neck surgery for severe Alzheimer's
This early-stage trial tests combining deep brain stimulation (a device that sends electrical pulses to the brain) with a neck surgery that aims to improve brain fluid drainage. It's for people with severe Alzheimer's who can still walk and do not have other major health issues.
BeijingAges 40–80 - NCT06889480Recruiting
Deep brain stimulation for severe Tourette syndrome
This trial tests a surgical procedure using deep brain stimulation to treat severe Tourette syndrome that hasn't improved with other treatments. It may help reduce tics by targeting specific areas in the brain.
Beijing, Beijing MunicipalityAges 18–60 - NCT07056361Recruiting
Testing brain stimulation for better movement in tremor and Parkinson's
This study tests whether stimulating specific brain areas (VOP/VIM) during deep brain stimulation surgery can improve movement and muscle control. It includes people with essential tremor or Parkinson's disease who are already scheduled for this surgery.
Pittsburgh, PennsylvaniaAges 18–75 - NCT07056348Recruiting
Brain stimulation to improve movement in Parkinson's or tremor
This study tests brain stimulation in a region called VOP/VIM to see if it can improve motor function. It is for people with movement disorders who are already getting deep brain stimulation (DBS) surgery.
Pittsburgh, PennsylvaniaAges 18–80 - NCT07049003RecruitingPhase 1
Deep brain stimulation for severe tremor
This trial tests a new type of deep brain stimulation (DBS) for people with severe tremor from essential tremor, multiple sclerosis, or cerebellar conditions who haven't improved with standard treatments. It targets a different brain area to see if it can reduce shaking and improve daily activities.
Cleveland, OhioAges 21 years+ - NCT07031544Recruiting
Deep brain stimulation for severe OCD
This study tests whether implanting a small device deep in the brain—like a pacemaker for OCD—can help people whose severe OCD hasn't gotten better with standard medications and therapy.
Guangzhou, GuangdongAges 18–65 - NCT07026734Recruiting
Speech and Swallow Effects of Deep Brain Stimulation in Parkinson's
This study looks at how deep brain stimulation (DBS) affects speech and swallowing in people with Parkinson's disease. It aims to help understand changes so doctors can better support you after DBS surgery.
Gainesville, FloridaAges 45–85 - NCT07022522Recruiting
Brain stimulation frequencies for impulse control in Parkinson's
This study tests whether stimulating specific parts of the brain's subthalamic nucleus at different frequencies can improve control over unwanted movements or impulses in people with Parkinson's disease. If you are planning to have DBS surgery, this trial may help find a better way to use the device.
Beijing, Beijing MunicipalityAges 40–80 - NCT06984757Enrolling by invitation
Brain waves and thinking in Parkinson's disease
This study looks at how brain activity relates to thinking and memory in people with Parkinson's disease, including those with and without cognitive issues, and those with deep brain stimulation. It uses EEG (a non-invasive brain wave recording) and sometimes mild brain stimulation (TMS or tACS) to understand these connections better.
Iowa City, IowaAges 18–99 - NCT06973512Recruiting
Brain stimulation for severe addiction
This trial tests a new brain stimulation approach for people with severe addiction that hasn't gotten better with other treatments. It uses deep brain stimulation guided by brain mapping to try to reduce cravings and help you stay abstinent.
Toronto, OntarioAges 25–65 - NCT06960096Recruiting
Cognitive decline after deep brain stimulation: an MRI study
This study uses MRI scans to see how deep brain stimulation (DBS) affects thinking and memory in people with Parkinson's disease. It may help researchers understand why some people experience cognitive changes after DBS surgery.
Charleston, South CarolinaAges 18 years+ - NCT06924086Recruiting
Adaptive deep brain stimulation for children with epilepsy
This trial tests a new type of brain stimulation (adaptive deep brain stimulation) that adjusts in real time to stop seizures in children with Lennox-Gastaut syndrome. It's for children who haven't gotten enough help from medications and have frequent drop seizures.
LondonAges 5–14 - NCT06909045Recruiting
Adaptive vs. regular deep brain stimulation for Parkinson's
This study compares two ways of using deep brain stimulation (DBS) — an adjustable ‘adaptive’ version that changes with your brain signals, versus the standard continuous setting. It aims to see which works better for people with Parkinson's disease who already have a specific type of DBS device.
LeuvenAges 18 years+
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Common questions
- Are there clinical trials for deep brain stimulation?
- Yes. Clin2 currently lists 193 recruiting deep brain stimulation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a deep brain stimulation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a deep brain stimulation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.