Clinical trials
Deep Brain Stimulation clinical trials
Below are recruiting deep brain stimulation clinical trials, each written for real people, not researchers. We’re tracking 208 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05182892Recruiting
Reducing speech side effects from DBS using speech recordings
This study tests whether automated analysis of your speech can help reduce speech problems caused by deep brain stimulation (DBS) in Parkinson’s disease. It may help your team adjust DBS settings to improve how you speak while keeping Parkinson symptoms controlled.
PragueAges 18 years+ - NCT03153670Recruiting
Brain scan study for people with deep brain stimulators
This study uses a 3‑tesla MRI (a type of detailed brain scan) in people who have deep brain stimulation (DBS) electrodes. The goal is to improve understanding of how the brain works; the scan is not meant to provide direct treatment benefit.
Toronto, OntarioAges 18–85 - NCT06752434Recruiting
Comparing two brain stimulation methods for dystonic tremor
This trial compares PSA (a type of deep brain stimulation targeting a different brain area) versus traditional STN DBS for treating dystonic tremor. It aims to see which method provides better tremor control with fewer side effects.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT04874220Recruiting
Brain study of real-world navigation in people with RNS
This study looks at how the brain works while people navigate in everyday life. It includes people who already have an RNS device placed in their brain and helps researchers understand the brain activity tied to spatial navigation.
Los Angeles, CaliforniaAges 12–70 - NCT04085406Recruiting
Deep brain stimulation for hard-to-treat low back pain
This trial studies deep brain stimulation (DBS) to reduce severe low back pain that hasn’t improved after many standard treatments and procedures. It may help people whose pain is long-lasting and not fixable with another surgery.
Los Angeles, CaliforniaAges 40–75 - NCT07115394Recruiting
Brain wave tracking during DBS for movement disorders
This study uses EEG (a non-invasive scalp recording) to measure brain signals while deep brain stimulation (DBS) is active. It aims to better understand how DBS affects brain activity in people with Parkinson's disease, essential tremor, or dystonia.
HamburgAges 35–85 - NCT07221539Recruiting
Waking the brain with ultrasound during sedation
This study uses focused ultrasound to stimulate a deep brain region and see if it can help people wake up faster from anesthesia. Healthy volunteers will be sedated and monitored while the ultrasound is applied.
Ann Arbor, MichiganAges 18–40 - NCT07671950Recruiting
Deep brain stimulation for neuropathic dental pain
This trial studies whether deep brain stimulation (DBS) can help people with a type of nerve-related tooth pain called atypical odontalgia. It is for those who have not found relief from standard treatments like medications or injections.
Vancouver, British ColumbiaAges 19–80 - NCT07442747RecruitingPhase 2
Aerobic exercise benefits in Parkinson's with DBS
This trial tests whether aerobic exercise (like walking or biking) can improve brain function in people with Parkinson's who have a deep brain stimulation (DBS) device. It may help you learn how exercise affects your symptoms and DBS treatment.
Cleveland, OhioAges 18 years+ - NCT06596447Recruiting
Brain activity study for severe OCD before DBS surgery
This study looks at how the brain processes approach and avoidance in people with severe OCD that hasn't improved with standard treatments. It aims to understand brain patterns that could help guide a future treatment called deep brain stimulation (DBS).
Houston, TexasAges 22–64 - NCT05701280Recruiting
Deep brain stimulation plus rehab after stroke
This trial looks at whether adding deep brain stimulation (a surgically placed device that delivers therapy signals) to rehab can improve arm function after a stroke. It is aimed at people whose stroke happened 12 months to 6 years ago and who still have arm weakness or poor control.
Phoenix, ArizonaAges 21 years+ - NCT06911229Recruiting
Walking and freezing study for Parkinson's with DBS
This study looks at how the brain controls walking and freezing of gait in people with Parkinson's disease who have deep brain stimulation (DBS). It aims to help understand why freezing happens and improve treatments.
Gainesville, FloridaAges 18–80 - NCT03437928Recruiting
Deep brain stimulation for severe, treatment-resistant depression
This trial tests whether deep brain stimulation (DBS, a surgically placed device that sends signals to the brain) can reduce symptoms of long-lasting major depression that has not improved with many treatments. You may be more likely to qualify if your depression has been present for years, has been resistant to multiple medications and therapies, and if you meet specific safety and testing requirements.
Dallas, TexasAges 22–70 - NCT03819738Recruiting
Brain scan during deep brain stimulation
This study checks how brain imaging works in people who already have a deep brain stimulation (DBS) device. If you have a DBS system, the study may help researchers better understand what the stimulation is doing in the brain.
Leuven, Vlaams-BrabantAges 18 years+ - NCT03832712Recruiting
Study for adults with essential tremor not helped by beta blockers
This trial looks at people with essential tremor (a shaking condition) whose usual medicine—beta blockers—didn’t work well or couldn’t be tolerated. The goal is to test a treatment approach that may improve tremor control and daily function.
GothenburgAges 18–75 - NCT03984643Recruiting
Testing computer planning for DBS surgery in essential tremor
This study looks at computer “planning algorithms” for DBS surgery in people with essential tremor whose medication hasn’t helped enough. It may help doctors program the DBS system more accurately for better tremor control.
Minneapolis, MinnesotaAges 21 years+ - NCT07700862Recruiting
Deep brain stimulation for tremor-dominant Parkinson's disease
This trial compares two ways to place electrodes in the brain to reduce tremors. It may help people with Parkinson's disease whose main symptom is shaking.
ShanghaiAges 18–80 - NCT04061135Recruiting
Study brain and movement patterns in Parkinson’s or tremor
This study looks at brain signals, thinking, and movement behaviors in people who have Parkinson’s disease or essential tremor and are being considered for deep brain stimulation (DBS) surgery. It may help researchers better understand how DBS affects the brain and day-to-day function.
Birmingham, AlabamaAges 18 years+ - NCT04071847Recruiting
Study tracking results after Abbott deep brain stimulator surgery
This study follows people who are getting a new Abbott deep brain stimulator (DBS) device or replacing the battery/implantable pulse generator to see how outcomes change over time. It mainly applies to certain DBS targets and diagnoses, and it uses follow-up visits to track results.
Tucson, ArizonaAges Any age - NCT04144972Recruiting
Closed-loop deep brain stimulation for long-lasting nerve pain
This trial tests a “smart” deep brain stimulation device that senses your brain signals and adjusts treatment to reduce severe, long-lasting pain. It may help people whose pain has not improved with multiple pain medicines and surgery cannot fix the cause.
San Francisco, CaliforniaAges 22–80 - NCT04296097Recruiting
Deep brain stimulation for severe, steady disabling tinnitus
This study tests whether deep brain stimulation (a device that sends controlled signals to the brain) can reduce severe, constant tinnitus that has not improved with usual treatments. It may help lower the loudness distress and improve daily quality of life for people whose tinnitus is especially disabling.
GrenobleAges 18–75 - NCT04354077Recruiting
Deep brain stimulation for opioid use disorder cravings
This trial studies whether deep brain stimulation (a device that delivers small electrical signals to the brain) can reduce cravings and improve symptoms in adults with opioid use disorder. You may be eligible if you have a long history of opioid dependence and have tried multiple treatment options without lasting success.
Pittsburgh, PennsylvaniaAges 22–65 - NCT04681534Recruiting
Testing safer adaptive deep brain stimulation for Parkinson’s
This trial studies an “adaptive” form of deep brain stimulation (DBS) that adjusts based on brain signals, and is mainly done when the DBS battery (IPG) needs replacement or when people are getting DBS for the first time. It aims to improve safety and effectiveness for Parkinson’s symptoms by using recorded brain activity during treatment.
MilanAges Any age - NCT04735458Recruiting
Brain network study for Parkinson’s or essential tremor
This study looks at how “inhibitory control” brain networks work in people with Parkinson’s disease or essential tremor. If you are eligible for surgery and can do the study tasks, your results may help researchers better understand movement disorders and guide future treatments.
Birmingham, AlabamaAges 18 years+
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Common questions
- Are there clinical trials for deep brain stimulation?
- Yes. Clin2 currently lists 208 recruiting deep brain stimulation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a deep brain stimulation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a deep brain stimulation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.