Clinical trials
Deep Brain Stimulation clinical trials
Below are recruiting deep brain stimulation clinical trials, each written for real people, not researchers. We’re tracking 193 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT02844049Recruiting
Quality-of-life study for treatment-resistant OCD with DBS
This study looks at whether deep brain stimulation (DBS) helps people with long-term, treatment-resistant obsessive-compulsive disorder (OCD), and how it affects quality of life. It involves careful screening because it’s meant for OCD that has not responded to several medication and therapy attempts.
CréteilAges 18–69 - NCT06329726Recruiting
Thinking and memory after brain stimulation for Parkinson's
This study looks at how deep brain stimulation (DBS) affects thinking and memory in people with Parkinson's disease over time. It compares results from people who have DBS and those who receive only medication.
Milan, LombardyAges 18–70 - NCT07835308RecruitingEarly Phase 1
Smart tuning of brain stimulation for better walking
This study is testing a new way to adjust deep brain stimulation (DBS) settings to improve walking in people with Parkinson's disease. If you have DBS and can walk with stimulation off, this trial may help fine-tune your treatment to improve your gait.
Minneapolis, MinnesotaAges 18 years+ - NCT07777419Recruiting
Thinking and mood after brain stimulation for Parkinson's
This study looks at how deep brain stimulation (a treatment that uses mild electrical pulses to help control movement) affects thinking and mood in people with Parkinson's disease. It is a joint study by a Swiss university hospital that uses records from usual care and tests over time.
BernAges 18–75 - NCT07700862Recruiting
Deep brain stimulation for tremor-dominant Parkinson's disease
This trial compares two ways to place electrodes in the brain to reduce tremors. It may help people with Parkinson's disease whose main symptom is shaking.
ShanghaiAges 18–80 - NCT07698236Enrolling by invitation
Temporal interference brain stimulation for Parkinson's disease
This trial tests a new non-invasive brain stimulation method called temporal interference to see if it can improve symptoms of Parkinson's disease. It is for people aged 40 to 80 who are on stable Parkinson's medications and have mild to moderate symptoms.
ShanghaiAges 40–80 - NCT07671950Recruiting
Deep brain stimulation for neuropathic dental pain
This trial studies whether deep brain stimulation (DBS) can help people with a type of nerve-related tooth pain called atypical odontalgia. It is for those who have not found relief from standard treatments like medications or injections.
Vancouver, British ColumbiaAges 19–80 - NCT07671261Recruiting
Brain surgery for schizophrenia guided by electrode mapping
This trial tests whether deep brain stimulation (DBS) guided by SEEG (a way to map brain activity with electrodes) can help treat schizophrenia. It is for people with moderate to severe symptoms who have not improved after trying at least two different antipsychotic medications.
Shanghai, Shanghai MunicipalityAges 18–55 - NCT04296097Recruiting
Deep brain stimulation for severe, steady disabling tinnitus
This study tests whether deep brain stimulation (a device that sends controlled signals to the brain) can reduce severe, constant tinnitus that has not improved with usual treatments. It may help lower the loudness distress and improve daily quality of life for people whose tinnitus is especially disabling.
GrenobleAges 18–75 - NCT06752434Recruiting
Comparing two brain stimulation methods for dystonic tremor
This trial compares PSA (a type of deep brain stimulation targeting a different brain area) versus traditional STN DBS for treating dystonic tremor. It aims to see which method provides better tremor control with fewer side effects.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT07455760Recruiting
Deep brain stimulation and speech sequencing study
This study looks at how deep brain stimulation affects speech in people with Parkinson's disease or essential tremor. It tests whether the stimulation changes the way you say sequences of sounds.
Boston, MassachusettsAges 18 years+ - NCT07442747RecruitingPhase 2
Aerobic exercise benefits in Parkinson's with DBS
This trial tests whether aerobic exercise (like walking or biking) can improve brain function in people with Parkinson's who have a deep brain stimulation (DBS) device. It may help you learn how exercise affects your symptoms and DBS treatment.
Cleveland, OhioAges 18 years+ - NCT06663969Recruiting
Temporal Interference Stimulation for Epilepsy
This trial tests a new, gentle way to stimulate specific brain areas using a special electrical signal. It aims to see if this can help people with epilepsy that hasn't improved with medication.
Beijing, Beijing MunicipalityAges 14–65 - NCT07417280Recruiting
Focused ultrasound for neurological disorders
This trial tests a gentle ultrasound treatment (LIFUS) for people with various brain conditions like epilepsy, tumours, or movement disorders. It aims to see if this non-invasive approach can help where other treatments are being used.
Toronto, OntarioAges 18–85 - NCT07325487Recruiting
Brain stimulation for walking and balance in SCA6 ataxia
This study tests a new kind of deep brain stimulation that adjusts automatically to improve balance and coordination in adults with SCA6, a genetic form of ataxia. It may help patients who can still walk but have moderate to severe symptoms.
Gainesville, FloridaAges 21–89 - NCT07325175Recruiting
Brain study to improve treatment for childhood dystonia
This study measures brain signals in children with dystonia to understand how the brain controls movement, with the goal of improving treatments like Deep Brain Stimulation (DBS). It also uses healthy children for comparison.
Cincinnati, OhioAges 6–21 - NCT07309133Recruiting
Brain signals in dystonia
This trial records brain signals during deep brain stimulation surgery to learn more about dystonia. It may help doctors understand how to improve treatment for people with this condition.
Newcastle upon Tyne, Tyne & WearAges 18 years+ - NCT07284784RecruitingPhase 2/Phase 3
Buntanetap for Parkinson's disease study
This trial tests an investigational drug called buntanetap in people with Parkinson's disease. It aims to see if the drug can improve symptoms. There are two groups: those who've taken buntanetap before (Cohort 1) and those with a deep brain stimulator (DBS) implant for at least a year (Cohort 2).
Birmingham, AlabamaAges 40–85 - NCT05348837Recruiting
Two-week sleep tracking for people with Parkinson’s
This study uses a wristband and a headband to track your sleep for two weeks. It’s meant to better understand sleep patterns in Parkinson’s, and may require temporarily changing your evening medication timing.
Aurora, ColoradoAges 18–80 - NCT07228286RecruitingEarly Phase 1
Using brain stimulation to help restore consciousness
This trial tests whether electrical stimulation of a deep brain area can improve awareness in people who have been in a coma-like state for at least 3 months after a brain injury. It aims to help those who have limited or no ability to communicate or use objects.
Boston, MassachusettsAges 18–55 - NCT06912282Recruiting
Deep brain stimulation for Meige syndrome
This study tests if a new deep brain stimulation approach using one electrode on both sides of the brain can help control the muscle spasms of Meige syndrome. It is for people whose symptoms have not improved enough with standard treatments.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07216222Recruiting
Brain response study for epilepsy or PTSD patients
This study looks at how the brain processes fear using a device already implanted to treat epilepsy or PTSD. It may help researchers understand fear responses and improve treatments.
Los Angeles, CaliforniaAges 18–70 - NCT05968976Recruiting
DBS surgery guided while awake versus asleep for essential tremor
This study compares two ways of doing a deep brain stimulation (DBS) procedure for people with essential tremor: using guidance while you are awake versus while you are asleep. It aims to find which approach is safer and works better for controlling disabling tremor.
Amsterdam, North HollandAges 18 years+ - NCT07127913Recruiting
Closed-loop brain stimulation for hard-to-treat bipolar depression
This trial tests a closed-loop deep brain stimulation system for people with bipolar II disorder whose depression has not responded to standard treatments. The device sends targeted electrical pulses to the brain based on real-time activity, aiming to reduce depression symptoms.
San Francisco, CaliforniaAges 22–70
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Common questions
- Are there clinical trials for deep brain stimulation?
- Yes. Clin2 currently lists 193 recruiting deep brain stimulation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a deep brain stimulation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a deep brain stimulation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.