Clinical trials
Degenerative Disease clinical trials
Below are recruiting degenerative disease clinical trials, each written for real people, not researchers. We’re tracking 118 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07552519Recruiting
Patient Outcomes in Spinal Disease Treatment
This study tracks how patients feel and function after receiving treatment for spinal disease (which may include procedures like spinal cord stimulation). Researchers want to understand what matters most to patients during their recovery.
Hasselt, LimburgAges 18 years+ - NCT07491575Recruiting
Evaluation of the 5C MEDic knee replacement system
This study tests a new knee replacement system (the 5C® MEDic Knee) in people having knee surgery at Leuven University Hospital. It aims to see how well the implant works for conditions like arthritis, fractures, or revision of a previous knee replacement.
Leuven, Vlaams-BrabantAges 18 years+ - NCT07396077Recruiting
Pre-op health boost for elderly spine surgery patients
This trial tests if a 6-week prehabilitation program (exercise and nutrition) before spine surgery helps elderly patients recover better. It is for people 75 or older with long-term lower back problems who need spinal fusion surgery.
Beijing, Beijing MunicipalityAges 75 years+ - NCT07087574Recruiting
Study of 3D printed tools for eating independence in rehab
This study tests whether using 3D printed tools can help people with neurodegenerative diseases eat more independently during their hospital stay. It focuses on patients who already need some help with meals, and aims to see if custom-made utensils or aids can give them more autonomy.
Hyères, VarAges 18 years+ - NCT06965426Recruiting
Eye vitamins and skin test: a crossover study
This study tests whether a supplement containing lutein, zeaxanthin, and meso-zeaxanthin can increase the amount of these nutrients in your skin. You will take the supplement and a placebo at different times to see if there is a difference.
Kansas City, MissouriAges 18 years+ - NCT06657248Recruiting
Study of a new partial knee implant for inner knee arthritis
This study tests how well a new partial knee implant works and how safe it is for people with arthritis on the inner side of the knee who still have healthy knee ligaments and can bend their knee well.
Potsdam, BrandenburgAges 18–75 - NCT05366140Recruiting
Implanet Jazz spine fusion for adults needing thoracolumbar stabilization
This trial looks at using the Implanet Jazz system during spine fusion surgery for adults who need stabilization in the middle-to-lower back. It may help patients by improving how well the fused spine heals and stays in place.
Lexington, KentuckyAges 18–100 - NCT03586258Recruiting
Brain scan and memory testing for people with brain injury
This study uses memory and thinking tests along with brain scans (likely MRI) to understand how different types of brain damage affect thinking. It may help doctors learn more about brain-related cognitive problems.
CaenAges 18 years+ - NCT03153670Recruiting
Brain scan study for people with deep brain stimulators
This study uses a 3‑tesla MRI (a type of detailed brain scan) in people who have deep brain stimulation (DBS) electrodes. The goal is to improve understanding of how the brain works; the scan is not meant to provide direct treatment benefit.
Toronto, OntarioAges 18–85 - NCT05971329Recruiting
Pilot study of bone graft for cervical disc wear and nerve symptoms
This trial tests a new bone graft product (ZetaFuse™) used during front-of-the-neck surgery to treat “wear and tear” in the cervical (neck) discs causing nerve problems. It may help relieve pain and nerve-related symptoms when other treatments haven’t worked.
Randwick, New South WalesAges 22–75 - NCT05655897Recruiting
Clips for leaky mitral valve in high-surgery-risk heart patients
This trial studies whether a device called GeminiOne can safely and effectively repair a leaky mitral valve using a catheter-based “clip” technique. It may help patients who have moderate-to-severe or severe valve leakage but are considered too high-risk for open surgery.
Suzhou, JiangsuAges 18 years+ - NCT07790328Recruiting
Long-term safety of the IntraSPINE implant for low back pain
This study checks how safe and effective the IntraSPINE implant is over time for people with low back pain from degenerative discs. The implant is placed in your spine to support it, and this trial helps see if it continues working well for years.
SaranAges 18 years+ - NCT07877766Enrolling by invitation
Microbiome study for patients having neck fusion surgery
This study looks at the bacteria in your body before and after neck surgery to see if they affect recovery. It may help improve care for future patients.
New York, New YorkAges 18–80 - NCT03810573Recruiting
Bone graft for spinal fusion surgery
This trial tests a new bone graft material to help bones in the lower spine fuse together after surgery. It may be an option for people with degenerative disc disease or a mild spinal slip.
Clayton, VictoriaAges 17–70 - NCT04631133Recruiting
Study of outcomes after surgery using the LISA implant
This study follows adults who get back surgery using the LISA implant to see how well they do afterward and how outcomes change over time. It focuses on people whose long-term, non-surgical care did not relieve low-back pain from specific age-related disc changes.
SilkeborgAges 18 years+ - NCT03048201Recruiting
Total Knee Replacement Registry Study for a Specific Knee Implant
This study tracks outcomes for people getting a total knee replacement using a specific knee implant system. It may help doctors understand which patients do best and how the implant performs over time.
Rancho Mirage, CaliforniaAges 22 years+ - NCT06029764Recruiting
Extended fusion for spinal disc vacuum signs
This trial tests a surgery that fuses one extra spinal disc to treat a 'vacuum sign' (air pockets in the disc) that hasn't caused symptoms yet. It aims to prevent future problems in people with lumbar disc disease who need fusion surgery.
Beijing, Beijing MunicipalityAges 18–60 - NCT07858643RecruitingPhase 1/Phase 2
A study of LDGraft for single-level lumbar fusion
This study tests a new graft material called LDGraft that may help fuse two vertebrae in your lower back after surgery. If you have degenerative disc disease in one lumbar level and haven't found relief from non-surgical treatments, this trial might be an option.
TbilisiAges 22–80 - NCT05332249Recruiting
Registry for Degenerative Spine Disease in the Neck and Low Back
This study is a registry (a way to collect health information) for people with wear-and-tear (“degenerative”) problems in the neck and/or low back. It may help doctors better understand these conditions and improve future care plans.
Seoul, KoreaAges 18–100 - NCT07834749Recruiting
Fortilink-SC device study for neck and spinal stenosis
This study tests a new spinal device to see how well it works for people with neck pain and spinal stenosis. It may help reduce pain and improve function.
Madrid, MadridAges Any age - NCT07834736Recruiting
Titanium implant for lower back disc pain
This study tests a new titanium implant to help stabilize the lower spine in people with painful, worn-out discs. It aims to see if the implant works well and is safe in everyday practice.
Madrid, MadridAges Any age - NCT07834931Recruiting
Spine implant for low back pain from disc degeneration
This study tests an implant placed in the lower spine to treat back pain caused by disc degeneration. It aims to see if the implant helps reduce pain and improve function in people who have not improved with other treatments.
Madrid, MadridAges Any age - NCT04601363Recruiting
Personalized spine registry for people with spinal hardware
This registry follows people who recently had spinal surgery where custom (patient-specific) spine hardware (like rods) was placed. It collects consent and health questionnaires to learn how these implants affect patients over time.
Aurora, ColoradoAges 10–85 - NCT07615491Recruiting
Safety and effectiveness study of spinal implants and bone materials
This study tracks how well spinal implants (Titania systems) and bone-filling materials (BONEGRAFT) work after surgery and whether patients experience any problems. Researchers will follow patients after cervical or lower spine surgery to confirm these devices are safe and effective in real-world use.
IzmirAges 18 years+
Hear when a new Degenerative Disease trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for degenerative disease?
- Yes. Clin2 currently lists 118 recruiting degenerative disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a degenerative disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a degenerative disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.