Clinical trials
Degenerative Spondylolisthesis clinical trials
Below are recruiting degenerative spondylolisthesis clinical trials, each written for real people, not researchers. We’re tracking 19 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07289737Recruiting
Comparing two spine surgeries for a slipped backbone
This study compares two types of spine surgery for a common condition where a lower back bone slips forward. It aims to see which surgery works better to relieve pain and improve function.
Yiwu, ZhejiangAges 50–90 - NCT05029726RecruitingPhase 4
Numbing medicine during back surgery to reduce pain
This trial tests a regional anesthesia (numbing medicine given near nerves) during minimally invasive lumbar spine surgery. The goal is to see if it helps control pain around surgery and improves recovery comfort.
Chicago, IllinoisAges 18–80 - NCT04418830Enrolling by invitation
Study of a spine cage implant for degenerative back problems
This trial studies how well specific lumbar (lower back) implant “cages” help fuse vertebrae in people with degenerative disc disease, spinal slippage, narrowing, curvature, or forward-bending deformity. It may help by testing an approach to improve stability and reduce symptoms after surgery.
La Jolla, CaliforniaAges 18 years+ - NCT06394089Recruiting
Spine surgery study for stenosis with mild slippage
This study tests a minimally invasive spine surgery (unilateral biportal endoscopy) to see if it works well for people with lumbar spinal stenosis who also have a mild vertebra slippage (spondylolisthesis). The goal is to improve leg symptoms like pain or numbness when walking.
Beijing, Beijing MunicipalityAges 50–80 - NCT05538416Recruiting
Back surgery approach trial for mild slip and leg pain
This trial compares a newer, “cortical bone trajectory” method with more traditional open surgery and a minimally invasive approach for treating certain low-back slips. It looks at short-term outcomes to see which approach helps patients recover better and relieve leg symptoms.
GroningenAges 18–75 - NCT03344484Recruiting
Compare two surgical approaches for degenerative low back slippage
This trial compares two different surgical approaches for degenerative spondylolisthesis (a “slipped” lower-back vertebra) to see which works better for pain and walking. You may be considered if you need surgery after months of non-surgical treatments.
Halifax, Nova ScotiaAges Any age - NCT06000319Enrolling by invitation
NMP fibers for spine fusion surgery
This study tests a new material called NMP fibers used during spine fusion surgery to treat conditions like degenerative disc disease, spinal stenosis, or spondylolisthesis. The goal is to see how well it works for patients having fusion in the neck or lower back.
Jasper, AlabamaAges 18 years+ - NCT06320899Recruiting
Comparing different rods for lower back spine surgery
This study tests two types of rods (mid/high-flex vs low-flex) used during back surgery for people with degenerative spine problems in the lower back. The goal is to see which type helps reduce pain and improve movement better.
AarbergAges 18–99 - NCT05238740Recruiting
Compare fusion results after two spine surgeries with added biologics
This study compares two types of spine surgery (ALIF or XLIF) for one spinal level, and tests how well the bones fuse when a specific bone-forming product is used. It also looks at how patients feel and function after surgery.
BernAges 18–70 - NCT07489001Recruiting
Comparing opioid-free to standard anesthesia for back surgery
This study compares two types of anesthesia for lower back surgery: one that uses opioids and one that does not. The goal is to see which approach controls pain better with fewer side effects.
Istanbul, MaltepeAges 18–75 - NCT06407063Recruiting
Long-term results after surgery for lumbar spinal stenosis
This study looks at patients who had back surgery for lumbar spinal stenosis and a condition called spondylolisthesis between 2007 and 2015. They want to see how many people needed another operation years later.
TromsøAges 18 years+ - NCT06265038Recruiting
Study of a new implant for lower back fusion surgery
This study tests a new implant called ReSpace TiCell Cage for TLIF surgery, which is a procedure to stabilize the lower back by fusing two vertebrae. It may be a good option if you have a degenerative spine condition causing pain or instability and are a candidate for this type of surgery.
Budapest, Pest CountyAges 18–80 - NCT06532253RecruitingPhase 1/Phase 2
Long-term safety of NVDX3 implant
This study checks the long-term safety of the NVDX3 implant. You can join if you already received this implant in a previous trial and are willing to have a yearly check-up for 10 more years.
LuxembourgAges 18 years+ - NCT05366140Recruiting
Implanet Jazz spine fusion for adults needing thoracolumbar stabilization
This trial looks at using the Implanet Jazz system during spine fusion surgery for adults who need stabilization in the middle-to-lower back. It may help patients by improving how well the fused spine heals and stays in place.
Lexington, KentuckyAges 18–100 - NCT03649490Enrolling by invitation
Testing new spinal implant materials for XLIF fusion
This study compares different advanced materials used in a specific spinal fusion surgery (XLIF). It aims to see which implant material helps the bone fuse well and safely over time.
Hartford, ConnecticutAges 18–80 - NCT07615491Recruiting
Safety and effectiveness study of spinal implants and bone materials
This study tracks how well spinal implants (Titania systems) and bone-filling materials (BONEGRAFT) work after surgery and whether patients experience any problems. Researchers will follow patients after cervical or lower spine surgery to confirm these devices are safe and effective in real-world use.
IzmirAges 18 years+ - NCT04204135Enrolling by invitation
Tracking hip flexor weakness after specific spine surgeries
This trial follows how hip flexor strength changes after two types of lower-back surgeries (ALIF or LLIF). It may help doctors better predict and prevent weakness in the hip and leg after surgery.
Chicago, IllinoisAges Up to 65 years - NCT06355791Recruiting
Study of the Minuteman device for spine fusion
This study looks at how well the Minuteman device works for people with chronic low back pain and leg symptoms caused by aging spine conditions. It tests if the device helps patients move better after surgery.
Newnan, GeorgiaAges 18 years+ - NCT07142174Recruiting
New implant for neck pain and nerve compression
This trial tests a new type of implant that is placed in the back of your neck to help open up space for nerves and improve spine alignment. It may help people with pain, numbness, or weakness from a pinched nerve or spinal cord compression caused by wear-and-tear changes.
RiyadhAges 18 years+
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Common questions
- Are there clinical trials for degenerative spondylolisthesis?
- Yes. Clin2 currently lists 19 recruiting degenerative spondylolisthesis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a degenerative spondylolisthesis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a degenerative spondylolisthesis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.