Clinical trials
Delirium clinical trials
Below are recruiting delirium clinical trials, each written for real people, not researchers. We’re tracking 205 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05168280Recruiting
Dexmedetomidine during brain surgery to prevent confusion in seniors
This trial tests whether giving a medication called dexmedetomidine during selective brain surgery can help prevent postoperative delirium, a sudden episode of confusion, in older adults. If you qualify, the study team would give the medication during the operation and compare outcomes after surgery.
Beijing, Beijing MunicipalityAges 65 years+ - NCT05195034Recruiting
Dexmedetomidine to prevent confusion after awake brain surgery
This trial looks at whether a medication called dexmedetomidine can reduce “postoperative delirium,” a temporary period of confusion after awake brain surgery. If you have the type of surgery the study focuses on, this could help your recovery and mental clarity afterward.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05198635Recruiting
Cerebral oxygen checks to lower confusion after carotid surgery
This trial looks at whether monitoring oxygen levels in the brain during carotid endarterectomy (a surgery to reduce stroke risk) can help reduce postoperative delirium, a sudden period of confusion after surgery. It may help patients recover more clearly after the operation by identifying risks early and guiding care.
Beijing, Beijing MunicipalityAges Any age - NCT05431595RecruitingPhase 2/Phase 3
Test a less sedating plan for agitated delirium in cancer
This study looks at whether using certain sleep/behavior medicines (called neuroleptics) with anti-seizure medicines can calm agitation from delirium without needing as much of the usual “neuroleptic” medicines. It may help people with advanced cancer who are confused and very restless or hard to settle.
Houston, TexasAges 18 years+ - NCT05525702Recruiting
VR sessions to lower confusion in ICU patients
This trial tests whether virtual reality (VR) activities can reduce delirium—new, sudden confusion—in people staying in the ICU. It may help patients feel clearer and more oriented during a longer ICU stay.
Beijing, Beijing MunicipalityAges 18–90 - NCT05713877RecruitingPhase 2
Melatonin to treat confusion in ICU patients
This Phase 2 trial tests whether melatonin can reduce delirium, a sudden confusion that can happen in the ICU. If you qualify, you may be given melatonin to see if it improves alertness and comfort during an expected longer ICU stay.
Montreal, QuebecAges 18 years+ - NCT05847010Recruiting
Study program to prevent postoperative delirium in older adults
This study adds an extra scientific program to help prevent confusion (“delirium”) after surgery in older adults. If you were already planned to join the main prevention program, this may help improve how care is delivered and how outcomes are measured.
BerlinAges 70 years+ - NCT05849597RecruitingPhase 3
Dexmedetomidine to prevent delirium after open-heart surgery
This trial tests whether a sedating medicine called dexmedetomidine can reduce the risk of “delirium” (sudden confusion) in the intensive care unit after open-heart surgery. If you’re having certain heart operations, it may help protect your thinking and alertness during recovery.
KamenitzAges 18 years+ - NCT05891873Recruiting
Study delirium during ICU care for stroke patients
This study looks at “delirium,” a sudden confusion that can happen during critical care, in people receiving ICU treatment for stroke. It includes both adults and children in specific ICU settings and may help clinicians better prevent or manage confusion during recovery.
BrnoAges Any age - NCT05913531Recruiting
Use of past delirium data from adult patients
This trial looks back at information already collected from past patients, focusing on delirium (confusion that can happen during serious illness or after anesthesia). It doesn’t test a new treatment—its goal is to learn patterns from existing records to improve future care.
BerlinAges 18–100 - NCT05990790RecruitingPhase 4
Comparing anesthetics and their effect on confusion after surgery
This study compares three different anesthesia medicines to see which one might lower the chance of confusion or delirium after major surgery. If you are 65 or older and having a long, planned non-heart surgery, this trial could help determine the safest option for you.
InnsbruckAges 65 years+ - NCT06007755Recruiting
Finding blood markers for confusion after heart surgery
This study is looking for certain substances in the blood that may show up if a person becomes confused or delirious after heart surgery. The goal is to find early warning signs so doctors can help prevent or treat this confusion.
Wuhan, HubeiAges 18 years+ - NCT06052397Recruiting
Sleep and body clock markers for confusion after surgery
This trial tests whether sleep patterns and body clock signals can help predict confusion after major orthopedic surgery. You would wear a watch that tracks movement to see how your sleep relates to recovery.
Boston, MassachusettsAges 70 years+ - NCT06092671Recruiting
Can FPCA prevent confusion in young kids after surgery?
This study tests whether a medicine called FPCA can prevent sudden confusion (delirium) in young children after surgery. If your child is having short surgery with mask anesthesia for the first time, this study may help them have a smoother recovery.
Wenzhou, ZhejiangAges 2–6 - NCT06107517Recruiting
Reducing delirium after heart bypass with early activity and sleep routines
This trial tests a program that combines gentle early activity and sleep-friendly routines after heart bypass surgery. It aims to reduce the risk of delirium—sudden confusion that can happen after surgery.
SingaporeAges 21–99 - NCT06133842Recruiting
Brain blood flow and confusion after surgery study
This trial looks at how well the brain controls its own blood flow during non-cardiac surgeries. It aims to see if problems with this regulation are linked to confusion after surgery (delirium).
Boston, MassachusettsAges 60 years+ - NCT06164314Recruiting
Calming medicine during brain tumor surgery
This trial tests if a calming medicine (dexmedetomidine) given during and after brain tumor surgery can help prevent confusion or delirium afterwards.
BeijingAges 18 years+ - NCT06176144Recruiting
Comparing two anesthetics for confusion after surgery in older adults
This trial compares two types of anesthesia (desflurane and sevoflurane) to see if one causes less confusion after surgery in older adults. It may help if you are 65 or older and having a non-heart, non-brain surgery lasting at least 2 hours.
Chengdu, SichuanAges 65–90 - NCT06256354Recruiting
Managing body temperature during cancer surgery to prevent confusion
This trial tests whether carefully managing a patient's body temperature during cancer surgery can reduce the risk of postoperative delirium and improve long-term survival. It is for older adults undergoing major cancer surgery.
Chizhou, AnhuiAges 65 years+ - NCT06285721Recruiting
Brain stimulation for treating delirium
This trial tests if a gentle electrical brain stimulation (tACS) can help treat delirium. If you are over 50 and have had delirium for at least two days, you may be eligible.
Nijmegen, GelderlandAges 50 years+ - NCT06294158Recruiting
Light and noise in the ICU and delirium risk
This study looks at how light and noise in the intensive care unit (ICU) might affect confusion and disorientation (delirium). By tracking these environmental factors, researchers hope to find ways to reduce delirium for ICU patients.
Graz, StyriaAges 18 years+ - NCT06326424Recruiting
Delirium check for older dementia patients in the ER
This study tests a way to identify delirium (sudden confusion) in older adults with Alzheimer's or other dementias while they are in the emergency room or hospital. It may help doctors detect and treat confusion faster.
Columbus, OhioAges 65 years+ - NCT06361238RecruitingPhase 3
Liraglutide to prevent confusion after heart surgery in seniors with diabetes
This trial is testing if liraglutide, a diabetes medication, can prevent delirium (sudden confusion) in older adults with type 2 diabetes who are having planned heart surgery. If you qualify, you may help find a new way to protect brain function after surgery.
Nanjing, JiangsuAges 60 years+ - NCT06423547Recruiting
Predicting confusion after surgery in older adults
This study looks at older patients (65 and older) who have had surgery and anesthesia. It aims to find who is at risk for confusion (delirium) and memory problems afterward. The goal is to help doctors prevent these issues.
BeijingAges 65–100
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Common questions
- Are there clinical trials for delirium?
- Yes. Clin2 currently lists 205 recruiting delirium studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a delirium trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a delirium trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.