Clinical trials
Delirium clinical trials
Below are recruiting delirium clinical trials, each written for real people, not researchers. We’re tracking 191 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06830369Recruiting
Virtual reality for comfort after major surgery in the ICU
This study tests if using virtual reality can help you feel more comfortable while recovering in the intensive care unit (ICU) after major surgery. If you are having heart or major abdominal surgery and will stay in the ICU for at least 2 days, you may be able to try a VR program to see if it eases your stay.
AmiensAges 18 years+ - NCT06411561Recruiting
Boosting memory after ICU stay for older adults
This study tests a combination of activities (like cognitive training and exercise) to help older adults recover thinking and memory after a serious illness in the ICU. It may help you regain sharpness and independence after leaving the intensive care unit.
Seattle, WashingtonAges 60 years+ - NCT04532606RecruitingPhase 4
Remimazolam to improve outcomes after bladder tumor surgery
This trial tests whether the anesthesia medicine remimazolam can improve recovery and longer-term outcomes after surgery for early-stage bladder cancer. If you are having a bladder tumor procedure through the urethra, this study may help doctors understand whether this anesthesia choice matters for prognosis.
Beijing, Beijing MunicipalityAges 50–90 - NCT06718764Recruiting
Bedside brain monitor study for sedated ICU patients
This study tests a new bedside monitoring system that tracks brain activity in ICU patients who are on a breathing machine and receiving sedative medications. It aims to help doctors better manage sedation and improve patient care.
New York, New YorkAges 18 years+ - NCT06687291Recruiting
Thinking and memory after stomach or esophagus cancer surgery
This study looks at how surgery and chemotherapy for stomach or esophageal cancer may affect your thinking, memory, and other cognitive functions. Researchers want to understand these changes to better support patients.
HuddingeAges 18 years+ - NCT06677502Enrolling by invitation
Cerebrolysin for delirium in ICU patients
This trial tests a medicine called Cerebrolysin to see if it helps reduce confusion and agitation (delirium) in patients who are critically ill and being treated in the ICU. It may be an option for you if you are over 18 and have delirium symptoms.
Lubin, Lublin VoivodeshipAges 18–100 - NCT06426953Recruiting
Proteins in blood to predict confusion after surgery in older diabetics
This study looks at proteins in your blood (TGF-β and INS-PI3K-AKT) to see if they can predict confusion after surgery (postoperative delirium) in older adults with diabetes. It may help doctors identify who is at higher risk.
Duyun, GuizhouAges 65 years+ - NCT06382649RecruitingPhase 2
Rivastigmine for drug-induced confusion
This study tests whether the drug rivastigmine can help people who are very agitated and confused due to certain drug side effects. If it works, it could calm them down and improve their confusion.
St Louis, MissouriAges 10 years+ - NCT06375265Recruiting
Sleep improvement program for older surgery patients
This trial tests a digital sleep improvement program for older adults who are about to have knee or hip replacement surgery. It aims to help you sleep better before and after surgery, which may improve your brain health and recovery.
Boston, MassachusettsAges 65 years+ - NCT06324955Recruiting
Using words during mask anesthesia in children
This study looks at whether simple spoken words during the process of falling asleep with a breathing mask can help children ages 5–10 have a better experience. The goal is to make anesthesia induction less scary for kids.
Boston, MassachusettsAges 5–10 - NCT05821972RecruitingPhase 4
Breathing-mist medicines for cleft palate surgery pain control
This trial tests whether a breathing mist of two medicines (dexmedetomidine plus ketamine) works better than dexmedetomidine alone during cleft palate repair surgery. It may help improve comfort and safety around anesthesia for eligible patients.
AsyutAges 1–4 - NCT06184945Recruiting
Behavioral and staffing strategies in the ICU
This study tests different ways of organizing care and supporting patients in the intensive care unit (ICU) to see if they can improve recovery and well-being. It focuses on adults who need a breathing tube and are in the ICU for at least a day.
Iowa City, IowaAges 19 years+ - NCT06192615RecruitingPhase 3
Can a sleep medication protect the brain after heart surgery?
This study tests whether a medicine called dexmedetomidine, given after heart surgery, can help prevent confusion and thinking problems in older adults during their intensive care stay. If you are 60 or older and having heart surgery with a heart-lung machine, this trial might be for you.
Los Angeles, CaliforniaAges 60 years+ - NCT06054828Recruiting
Modified ICU program to prevent confusion
This trial tests a special program for people in the ICU who are on a breathing machine. The program aims to prevent confusion and help patients recover better.
Taipei, National Taiwan UniversityAges 18 years+ - NCT05929703Recruiting
Caring for hospitalized older adults
This study tests a new approach to caring for older adults in the hospital to prevent confusion (delirium). It involves having a family member or care partner stay with the patient during the hospital stay.
Orange, CaliforniaAges 70 years+ - NCT04289142RecruitingPhase 4
Testing memory effects of dexmedetomidine during heart surgery
This study looks at how a sleep medicine called dexmedetomidine affects thinking and memory after heart surgery. It compares cognitive outcomes over time to see if this sedation choice changes long-term brain function.
Vancouver, British ColumbiaAges 60 years+ - NCT05649800Recruiting
Study brain and blood-vessel changes in older adults after stroke
This study looks at how blood flow in the brain and related brain processes change after stroke, especially when someone also has conditions like dementia, depression, or delirium. It may help researchers understand what drives these problems and how they connect.
Leicester, LeicestershireAges 65 years+ - NCT05595954Recruiting
Personalized anesthesia plan to protect the brain during heart surgery
This trial studies whether tailoring anesthesia and monitoring the brain’s blood-flow control during heart surgery can improve neurological outcomes (brain-related function and recovery). It may help by guiding anesthesia in a more individualized way and checking how well the brain is protected during the operation.
BaselAges 65 years+ - NCT05514405Recruiting
Testing two anesthesia medicines to prevent confusion after surgery
This trial tests whether using remimazolam or propofol during hip or knee replacement surgery can lower the risk of postoperative delirium, a sudden, short-term confusion that can happen after anesthesia. It may help people who are at higher risk of postoperative confusion by finding the safer anesthesia approach.
SeoulAges 65–100 - NCT05091242RecruitingPhase 2/Phase 3
Preventing agitation after anesthesia in babies up to 1 year old
This study tests a way to reduce post-surgery agitation (confusion or restlessness) in babies aged 3 to 12 months who need anesthesia for a procedure. The goal is to make recovery calmer and safer for your baby.
Perth, NedlandsAges 3 months–1 year - NCT04493996Recruiting
Cognitive training before heart surgery to protect memory
This trial tests whether brain-focused cognitive training before elective heart surgery can help reduce memory and thinking problems afterward. If you qualify, you may do language-based thinking exercises and complete short brain tests around the time of surgery.
Bad NauheimAges 18 years+ - NCT04007432Recruiting
Testing nighttime low-oxygen levels after hip fracture surgery
This study checks how often older adults get low oxygen during the night after hip fracture surgery. It may help doctors better monitor and improve care during hospital recovery.
ParisAges 70 years+ - NCT03438526RecruitingPhase 4
Melatonin treatment for low-activity delirium in ICU patients
This trial tests whether giving melatonin (or a placebo) can help adults in the intensive care unit who have a specific type of confusion called low-activity delirium. It aims to improve recovery by supporting sleep–wake regulation in the ICU.
BaselAges 55 years+
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Common questions
- Are there clinical trials for delirium?
- Yes. Clin2 currently lists 191 recruiting delirium studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a delirium trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a delirium trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.