Clinical trials
Depression and Anxiety Symptom clinical trials
Below are recruiting depression and anxiety symptom clinical trials, each written for real people, not researchers. We’re tracking 165 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07055906Recruiting
Video coaching to help Latino families talk about race
This study tests a video-based coaching program to help Latino parents and their 10–14-year-old children talk about race and ethnic background. Families will be recorded having a conversation, then get feedback to strengthen their communication.
Harrisburg, PennsylvaniaAges 10–14 - NCT07041073Recruiting
Brain training for emotion control in depression
This trial tests if a non-invasive brain training technique called neurofeedback can help people with major depression improve how they manage emotions. You participate by doing computer tasks while your brain activity is measured and shown back to you, teaching you to regulate your emotions better.
Sabadell, Barcelona, CataluñaAges 18–65 - NCT07033741Recruiting
EMDR therapy for depression symptoms study
This trial studies whether EMDR therapy helps reduce depressive symptoms and what factors predict improvement. It is open to patients with anxiety, depression, PTSD, or dissociation symptoms.
Turin, TurinAges 18 years+ - NCT07007234Recruiting
Sedentary behavior and depression study
This study looks at how sitting or being inactive (sedentary behavior) affects depressive symptoms. If you have mild to severe depression, you may be able to join and help find out if moving more can improve your mood.
São Paulo, SOAges 18 years+ - NCT06921512Recruiting
Chinese therapeutic exercise for anxiety and depression
This study tests whether a traditional Chinese mind-body exercise (Daoyin) can help people with mild to moderate anxiety and depression. It also looks at how the exercise might affect your body and mind.
ShanghaiAges 18–65 - NCT06909669Recruiting
Brief therapy for anxiety, depression, or physical symptoms
This study tests short-term psychological treatments to help people with mild or moderate emotional symptoms like anxiety, depression, or physical complaints (such as pain or fatigue) that may be linked to stress. The goal is to see if these brief therapies can improve how you feel.
Córdoba, CórdobaAges 18 years+ - NCT05549102Recruiting
CBT therapy study for anxiety and brain circuit changes
This trial studies whether a specific form of talk therapy (CBT) changes brain activity in people with moderate anxiety. It may help your care team understand what works best and how brain “circuits” respond to treatment.
LondonAges 18–64 - NCT06828276Recruiting
Online therapy for Farsi and Dari speaking young migrants
This study tests if a culturally adapted online therapy program helps reduce anxiety and depression in young Farsi or Dari speaking migrants. You would use your computer or phone for 6 to 10 weeks at home.
StockholmAges 15–29 - NCT06648928Enrolling by invitation
App for reducing PTSD in Florida 9/11 responders
This study is testing a mobile app called PTSD Coach, along with support from a clinician, to help World Trade Center responders in Florida reduce symptoms of post-traumatic stress. It may be a good fit if you have some PTSD symptoms but not severe alcohol or drug use, and you are not already receiving PTSD treatment.
Miami, FloridaAges Any age - NCT06462196Recruiting
Study of Depression, Bipolar Disorder & Suicide Risk
This study looks at how depression, bipolar disorder, and suicide risk naturally change over time. It aims to better understand these conditions so doctors can improve treatments.
Bethesda, MarylandAges 18–120 - NCT06441786Recruiting
Group therapy for depression and anxiety in autistic teens
This trial tests a group therapy that helps teenagers with autism who also have anxiety or depression learn skills to manage their thoughts and feelings. It takes place at a clinic in Stockholm.
Haninge, Stockholm CountyAges 15–18 - NCT06273982Enrolling by invitation
Telehealth for anxiety and depression in youth
This study tests whether a behavioral telehealth program can help teens and children with anxiety or depression. It is designed for patients in community health centers and includes support from a parent or guardian.
Portland, OregonAges 8–16 - NCT06004115RecruitingPhase 4
Brain scanning study for depression and anxiety
This study uses brain scans (fMRI) to understand how people with both depression and anxiety respond to threat. If you have either or both conditions, participating could help researchers find better treatments.
Tulsa, OklahomaAges 18–65 - NCT05836090Recruiting
Family Spirit Strengths program for pregnant people and caregivers
This trial tests a family-focused program to support mental health and reduce risks related to substance use. It may help you if you’re pregnant or caring for a child 24 months or younger and you’re experiencing depression/anxiety and/or substance-use risk.
Chinle, ArizonaAges 14 years+ - NCT05754151Recruiting
Mobile therapy for anxiety and depression in adults 40+
This trial tests whether a phone or tablet version of cognitive behavioral therapy (CBT) can help people ages 40 and older with anxiety or depression. It may help you manage symptoms with skills you can use between sessions.
New York, New YorkAges 40 years+ - NCT05658796Recruiting
Program to reduce opioid use after hip or knee replacement
This trial tests a support program called RXWell to help people use less opioid pain medicine after elective hip or knee replacement surgery. It may help by addressing anxiety and depression symptoms that can affect pain and recovery.
Monroeville, PennsylvaniaAges 18–100 - NCT05567640Recruiting
Smart digital mental health support
This study tests a digital mental health program that uses smart technology to personalize your experience and keep you engaged. If you join, you may get a more tailored approach to improving your mental well-being.
Boston, MassachusettsAges 18 years+ - NCT05589337Recruiting
Baduanjin exercise program for depression and anxiety symptoms
This study tests whether practicing Baduanjin (a gentle movement/exercise) can reduce symptoms of depression and anxiety. It may help people who are able to follow instructions and communicate clearly.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT04572321Enrolling by invitation
Teen depression and suicide research study for youth
This study looks at depression and suicidal thoughts or behaviors in children and teens. It may help researchers better understand these risks and improve supports for young people.
Dallas, TexasAges 8–20 - NCT07398040Enrolling by invitation
Anti-inflammatory diet for anxiety and depression
This study tests whether following a personalized anti-inflammatory diet can help reduce symptoms of anxiety, depression, or stress. You would need to live in Zaragoza, speak Spanish, and already have a low-to-moderate Mediterranean diet score.
Zaragoza, ZaragozaAges 18 years+ - NCT06442423RecruitingPhase 1
Psilocybin study for people with psychiatric symptoms
This trial tests if psilocybin, a substance found in certain mushrooms, can help people with various mental health symptoms that affect daily life. You would take a single dose in a supervised setting and be monitored for changes in your mood and well-being.
New Haven, ConnecticutAges 18 years+ - NCT06429956Recruiting
Combined online therapy for anxiety and depression
This trial tests a new type of therapy that combines different treatment methods for anxiety and depression. It is completely online, so you can join from home, and it aims to help you feel better by tailoring the therapy to your needs.
AarhusAges 18 years+ - NCT06384196Recruiting
Virtual-reality therapy for anxiety and depression in young people
This study tests a new virtual-reality therapy for young people struggling with anxiety or depression. It aims to help you feel better by addressing both conditions together.
BadalonaAges 16–29 - NCT05699525Recruiting
Personalized app for cognitive behavioral therapy for young adults
This trial tests a mobile app that delivers personalized cognitive behavioral therapy (a structured talk-therapy approach that helps change unhelpful thoughts and behaviors). It may help reduce symptoms of anxiety, depression, or bipolar disorder for people who fit the study’s timing and safety requirements.
New York, New YorkAges 18–25
Hear when a new Depression and Anxiety Symptom trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for depression and anxiety symptom?
- Yes. Clin2 currently lists 165 recruiting depression and anxiety symptom studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a depression and anxiety symptom trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a depression and anxiety symptom trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.