Clinical trials · Chicago, IL
Diabetes Mellitus clinical trials in Chicago
We’re tracking 35 recruiting diabetes mellitus studies with a site in or near Chicago — including Early Phase 1, Phase 1/Phase 2, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies near Chicago
- NCT07228117Recruiting
Testing a new automated insulin pump for people with diabetes
This study tests a new automated insulin delivery system (a pump that helps manage blood sugar) in children and adults with diabetes. It aims to see if the system is safe and easy to use in daily life.
Chicago, IllinoisAges 7–85 - NCT06217302RecruitingPhase 3
Sotagliflozin for kidney protection in type 1 diabetes
This study tests whether sotagliflozin (a pill that helps control blood sugar and protects the kidneys) can slow down kidney function decline in people with type 1 diabetes and diabetic kidney disease. You may qualify if you have had type 1 diabetes for at least 8 years, have moderate kidney damage, and are on standard treatments.
Chicago, IllinoisAges 18–75 - NCT06988306Recruiting
Lifestyle program to prevent diabetes after pregnancy
This study tests a lifestyle program (like diet and activity guidance) to help prevent diabetes after pregnancy in people who had gestational diabetes. You'll be part of a home visiting program and learn ways to stay healthy.
Chicago, IllinoisAges 18 years+ - NCT04786262RecruitingPhase 3
Study of VX-880 for long-standing type 1 diabetes
This Phase 3 trial tests how safe, tolerable, and effective VX-880 is for people with type 1 diabetes who have had it for many years. It may help reduce problems related to blood sugar swings, especially severe low blood sugar episodes.
Chicago, IllinoisAges 18–65 - NCT05544266Recruiting
Study rare diabetes patterns to better guide diagnosis
This study looks at people who may have a “non-typical” form of diabetes, including rare genetic causes or unusual symptoms. It may help your care team understand what type of diabetes you have and whether specific genetic testing could explain it.
Chicago, IllinoisAges Any age - NCT06112418Recruiting
Personalized vs standard care to prevent heart attacks
This trial compares two ways to prevent heart attacks and strokes: one uses a special heart CT scan to guide care, the other uses standard risk factors like blood pressure and cholesterol. You may be eligible if you are older (men over 55, women over 65) and have diabetes, prediabetes, or metabolic syndrome.
Chicago, IllinoisAges 55 years+ - NCT06887049Recruiting
Screening for emotional health in type 2 diabetes
This study tests a program to regularly screen and support emotional health in adults with type 2 diabetes and high blood sugar (A1C greater than 8%). It aims to improve both emotional well-being and diabetes management.
Chicago, IllinoisAges 18 years+ - NCT07064473RecruitingPhase 3
Testing vicadrostat plus empagliflozin for diabetes, high blood pressure, and heart disease
This study tests a new pill called vicadrostat taken with another medicine (empagliflozin) to see if it helps people with type 2 diabetes, high blood pressure, and heart disease. It may reduce the risk of heart problems, but you must not have had heart failure or use certain other heart medications.
Chicago, IllinoisAges 18 years+ - NCT06950788Recruiting
Glucose changes in cirrhosis patients around liver transplant
This study looks at how the body processes sugar (glucose) in people with cirrhosis who are waiting for a liver transplant. It aims to track changes in blood sugar control before and after transplant, which may help improve care for patients with liver disease.
Chicago, IllinoisAges 18–75 - NCT01630850Recruiting
Islet cell transplant for brittle type 1 diabetes
This trial studies whether transplanting insulin-producing islet cells can improve blood sugar control and reduce severe low blood sugar in people with “brittle” type 1 diabetes. It’s meant for adults with long-standing insulin dependence and troublesome, hard-to-control hypoglycemia.
Chicago, IllinoisAges 18–70 - NCT06517576Enrolling by invitation
Remote monitoring for type 2 diabetes
This trial tests using a smartphone to help manage your blood sugar. It's for people with type 2 diabetes who take insulin and whose blood sugar is not well controlled (HbA1c 8% or higher).
Chicago, IllinoisAges 18 years+ - NCT06783309RecruitingPhase 1/Phase 2
Testing CNP-103 for newly diagnosed type 1 diabetes
This trial tests a new study drug called CNP-103 for people ages 12-35 who were recently diagnosed (within 6 months) with stage 3 type 1 diabetes. The goal is to see if the drug can help preserve the body's ability to make some insulin, potentially slowing the need for more insulin shots.
Chicago, IllinoisAges 12–35 - NCT06964087RecruitingPhase 2
Testing OPT101 for type 1 diabetes
This trial tests an investigational drug called OPT101 in people with type 1 diabetes. It aims to see how the drug works in the body and whether it can help preserve insulin production, especially in those diagnosed recently or within the last 20 years.
Chicago, IllinoisAges 18–50 - NCT06575426RecruitingPhase 1/Phase 2
Pig pancreatic cell transplant for type 1 diabetes
This trial tests a new treatment made from pig pancreatic cells (called OPF-310) that are placed under the skin to help control blood sugar in people with type 1 diabetes. It is for those whose diabetes is difficult to manage and who have dangerous low blood sugar episodes.
Chicago, IllinoisAges 35–70 - NCT07091318RecruitingEarly Phase 1
CBT for insomnia in type 1 diabetes
This study tests whether cognitive behavioral therapy for insomnia (CBTi) can improve sleep in people with type 1 diabetes. It may help those who have poor sleep quality and use a continuous glucose monitor.
Chicago, IllinoisAges 18–65 - NCT07662135RecruitingPhase 3
A study of elecoglipron for type 2 diabetes with kidney problems
This trial tests a new medicine called elecoglipron to see if it helps control blood sugar in people with type 2 diabetes who also have reduced kidney function. You would continue taking your current SGLT2i medication (like dapagliflozin).
Chicago, IllinoisAges 18 years+ - NCT04687215Recruiting
Spinal cord stimulation for painful diabetic nerve pain
This trial studies whether a spinal cord stimulator can reduce pain from diabetic nerve damage in the legs. It focuses on people with long-lasting type 2 diabetes and significant, treatment-resistant pain.
Chicago, IllinoisAges 18 years+ - NCT01241864RecruitingPhase 2
Islet transplant for type 1 diabetes after kidney transplant
This trial tests whether transplanting insulin-producing “islet” cells can better control blood sugar in people who have already received a kidney transplant. It’s mainly for adults with type 1 diabetes whose body is no longer making enough insulin, while they are on kidney-transplant medicines.
Chicago, IllinoisAges 18–68 - NCT07784725RecruitingPhase 3
Study of a weight loss injection for adults with obesity
This study tests a new medicine to help adults with obesity or overweight lose weight. It's for people who have had trouble losing weight in the past and don't have diabetes.
Chicago, IllinoisAges 18 years+ - NCT06709755Recruiting
Helping Teens with Type 1 Diabetes Feel Less Stressed
This study tests a program to help teenagers with type 1 diabetes feel less stressed and overwhelmed about their diabetes. It is done entirely through video visits, so you can join from home.
Chicago, IllinoisAges 14–18 - NCT05762107RecruitingTeam says not enrollingPhase 2
Drug ZT-01 to reduce low blood sugar at night
This Phase 2 study tests ZT-01 to help prevent night-time low blood sugar (hypoglycemia) in people with type 1 diabetes. It may help if you’ve had low blood sugar during sleep or are at high risk based on recent glucose monitoring.
Chicago, IllinoisAges 18–75 - NCT06739122RecruitingPhase 3
A study of dulaglutide for children with type 2 diabetes
This trial tests if a weekly injection of dulaglutide (Trulicity) can help children with type 2 diabetes control their blood sugar when used together with metformin and/or insulin. It may be an option for kids who are overweight.
Chicago, IllinoisAges 10–17 - NCT07521475Recruiting
Fully Closed Loop Insulin Pump for Type 2 Diabetes
This study tests a new automated insulin pump system (Omnipod) that adjusts insulin doses on its own throughout the day for people with type 2 diabetes. The goal is to see if it helps keep blood sugar levels more stable while reducing the burden of manual insulin management.
Chicago, IllinoisAges 18–75 - NCT07579702Recruiting
Omnipod 6 Versus Omnipod 5 Insulin Pump System
This study compares two versions of the Omnipod insulin pump system to see if the newer Omnipod 6 works better at managing blood sugar than the current Omnipod 5. You'll wear one of these systems for several months and share data about how well it helps control your diabetes.
Chicago, IllinoisAges 14–75
Hear when a new Diabetes Mellitus trial opens near Chicago, IL
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Diabetes Mellitus trials in other cities
Where these studies are running near Chicago
Institutions with a site for the recruiting diabetes mellitus studies listed above.
- University of Chicago · 9 studies
- Northwestern University · 8 studies
- University of Illinois · 3 studies
- Research Site · 2 studies
- Accellacare - Duly Health and Care
- Accellacare of Duly Health and Care
- Ann & Robert H. Lurie Children's Hospital of Chicago
- Cedar Crosse Research Center
What taking part in a diabetes mellitus study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting diabetes mellitus studies in Illinois.
Common questions
- Are there diabetes mellitus clinical trials near Chicago?
- Yes. We're currently tracking 35 recruiting diabetes mellitus studies with a site near Chicago, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a diabetes mellitus study near Chicago?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Chicago to take part?
- Not necessarily. These studies have a site near Chicago, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a diabetes mellitus trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New diabetes mellitus studies open near Chicago regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.