Clinical trials · Philadelphia, PA
Diabetes clinical trials in Philadelphia
We’re tracking 60 recruiting diabetes studies with a site in or near Philadelphia — including Phase 1, Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies near Philadelphia
- NCT06880835Recruiting
Inhaled insulin vs injected insulin for exercise blood sugar drops in type 1 diabetes
This trial tests whether a new inhaled insulin (Technosphere) causes fewer low blood sugar episodes during exercise compared to standard injected insulin in people with type 1 diabetes who use an automated insulin pump. It may help you avoid hypoglycemia while staying active.
Philadelphia, PennsylvaniaAges 18–65 - NCT05390892RecruitingPhase 4
Preventing kidney and heart damage in type 2 diabetes
This study tests whether diabetes medicines can help prevent worsening heart and kidney problems in people with type 2 diabetes. You’ll be assigned by chance to one of these medicine types, and your other care will be adjusted for safety.
Philadelphia, PennsylvaniaAges 40–80 - NCT07184775Recruiting
CGM vs finger-stick for type 2 diabetes in pregnancy
This trial tests if using a continuous glucose monitor (CGM) helps manage blood sugar better than finger-stick checks in pregnant women with type 2 diabetes. It aims to see if CGM leads to better sugar control and possibly healthier outcomes for you and your baby.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05846802Recruiting
Gastroparesis and stomach symptoms registry for adults
This registry is for adults with long-lasting stomach emptying problems or related symptoms, helping researchers better understand patterns of nausea, pain, and fullness. You may be able to join if you meet specific symptom and test results, and can complete a stomach-emptying scan.
Philadelphia, PennsylvaniaAges 18–85 - NCT07222332RecruitingPhase 3
Baricitinib for new type 1 diabetes to save insulin-making cells
This trial tests if baricitinib, a pill that calms the immune system, can protect the remaining insulin-making cells in people newly diagnosed with type 1 diabetes. If it works, you might keep making some of your own insulin longer.
Philadelphia, PennsylvaniaAges 1–35 - NCT06995651RecruitingPhase 1
Dorzagliatin for blood sugar in cystic fibrosis
This study tests a drug called dorzagliatin to see if it can help control blood sugar in adults with cystic fibrosis who have pancreatic insufficiency and abnormal glucose tolerance.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07743450RecruitingPhase 3
Daily oral medication for weight loss in adults with obesity and type 2 diabetes
This study tests a once-a-day pill for adults who are overweight or have obesity and also have type 2 diabetes. The goal is to see if the medication helps with weight loss and improves blood sugar control.
Philadelphia, PennsylvaniaAges 18 years+ - NCT04024631Recruiting
Study genes and diabetes risk using body measurements
This study looks at how genetic risk relates to developing type 2 diabetes, using information from a biobank and body measurements like weight. It may help researchers better identify who is at higher risk before diabetes starts.
Philadelphia, PennsylvaniaAges 10–70 - NCT07282613RecruitingPhase 3
CagriSema for blood sugar and weight in children with type 2 diabetes
This study tests a new medicine called CagriSema to see if it can lower blood sugar and help with weight loss in children and teens with type 2 diabetes. It compares the medicine to a placebo (a look-alike with no active drug) over several months.
Philadelphia, PennsylvaniaAges 10–18 - NCT06837181Recruiting
Understanding diabetes complications in cystic fibrosis
This study looks at how long-term diabetes affects people with cystic fibrosis. It helps researchers understand complications and improve care.
Philadelphia, PennsylvaniaAges 12 years+ - NCT02986984Recruiting
Kidney biopsy study for people with diabetic kidney disease
This study aims to learn more about diabetic nephropathy (kidney problems caused by diabetes) using planned kidney tissue samples. You may benefit by helping researchers understand the disease better, and you may be eligible if you already have a medically needed kidney biopsy scheduled.
Philadelphia, PennsylvaniaAges 18–100 - NCT04786262RecruitingPhase 3
A study of VX-880 and VX-017 for type 1 diabetes
This study tests two investigational drugs, VX-880 and VX-017, for people with type 1 diabetes who have trouble controlling their blood sugar and have frequent severe low blood sugar episodes. The goal is to see if these drugs can improve blood sugar control and reduce dangerous lows.
Philadelphia, PennsylvaniaAges 18–65 - NCT07167004Recruiting
Boosting nutrition with whole grains for prediabetes or diabetes
This study tests if providing whole-grain foods through online grocery shopping can improve nutrition for people with prediabetes or diabetes. It aims to help you manage your blood sugar better.
Philadelphia, PennsylvaniaAges 45–70 - NCT07662213RecruitingPhase 3
Elecoglipron vs semaglutide for type 2 diabetes
This study tests an experimental diabetes pill (elecoglipron) to see if it works as well as a current medicine, semaglutide, for people with type 2 diabetes who also have heart risk factors. It aims to help better control blood sugar and weight.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06832410RecruitingPhase 3
Testing VX-880 for type 1 diabetes with a kidney transplant
This trial tests a new treatment called VX-880 for people who have had type 1 diabetes for at least 5 years and have already received a kidney transplant. The goal is to see if VX-880 can improve blood sugar control while you continue your current transplant medications.
Philadelphia, PennsylvaniaAges 18–65 - NCT04661215Recruiting
Testing stomach opening muscle problems in people with gastroparesis
This study looks at whether abnormal function of the pyloric “stomach outlet” muscle is linked to gastroparesis symptoms (slow stomach emptying). It may help researchers better understand what causes symptoms and guide future treatments.
Philadelphia, PennsylvaniaAges 18–85 - NCT06325202Recruiting
A study on preventing low blood sugar with a closed loop system
This trial tests whether a closed-loop insulin pump combined with education can help people with type 1 diabetes better recognize and avoid dangerously low blood sugar. It may be a good fit if you've had diabetes for a long time and have trouble sensing when your blood sugar drops.
Philadelphia, PennsylvaniaAges 18–75 - NCT06907147Recruiting
Renal denervation for uncontrolled high blood pressure
This trial tests a procedure called renal denervation to lower blood pressure in people whose medication isn't enough. It uses a special catheter to calm nerves near the kidneys that may be overactive.
Camden, New JerseyAges 18–80 - NCT07217249Enrolling by invitation
Donor diabetes and cornea transplant success at 5 years
This study looks at how a donor's diabetes might affect the long-term success of a specific type of cornea transplant called DMEK. Participants from an earlier study (DEKS) will be followed for up to 5 years to see how well the transplant is doing.
Bala-Cynwyd, PennsylvaniaAges 30–93 - NCT06628908RecruitingPhase 3
Study of suzetrigine for painful diabetic nerve damage
This trial tests an experimental medicine called suzetrigine to see if it can safely reduce pain caused by nerve damage from diabetes (diabetic peripheral neuropathy). It might be an option if you have had daily pain in both legs and current treatments haven't worked well enough.
Media, PennsylvaniaAges 18–80 - NCT06112418Recruiting
Personalized vs standard care to prevent heart attacks
This trial compares two ways to prevent heart attacks and strokes: one uses a special heart CT scan to guide care, the other uses standard risk factors like blood pressure and cholesterol. You may be eligible if you are older (men over 55, women over 65) and have diabetes, prediabetes, or metabolic syndrome.
Marlton, New JerseyAges 55 years+ - NCT07340320RecruitingPhase 2
CX11 tablets for type 2 diabetes
This trial tests an experimental drug called CX11 to see if it helps control blood sugar in people with type 2 diabetes who are already taking metformin. It may be an option for you if your blood sugar is not well controlled and you meet the health requirements.
Berlin, New JerseyAges 18–75 - NCT07351045RecruitingPhase 3
Study of enicepatide for weight loss in obesity or overweight
This study tests a new injectable medication called enicepatide for people with obesity or overweight who have not been able to lose weight through diet and exercise alone. It may help you lose weight and improve health conditions linked to excess weight.
West Chester, PennsylvaniaAges 18 years+ - NCT07271186RecruitingPhase 2
Study of an experimental drug for kidney disease from type 2 diabetes
This study tests an investigational drug called ALN-ANG3 to see if it can help people with diabetic kidney disease. The drug may reduce kidney damage and slow down the loss of kidney function. If you join, you will get the study drug or a placebo (a dummy shot) and be followed by a study doctor.
West Chester, PennsylvaniaAges 18–80
Hear when a new Diabetes trial opens near Philadelphia, PA
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Diabetes trials in other cities
Where these studies are running near Philadelphia
Institutions with a site for the recruiting diabetes studies listed above.
- University of Pennsylvania · 5 studies
- Children's Hospital of Philadelphia · 3 studies
- Suburban Research Associates · 3 studies
- Temple University Hospital · 2 studies
- Advanced Heart and Vascular Institute of Hunterdon
- AURORA-2 Clinical Site
- Children's Hosptl Philadelphia
- Hassman Research Institute
What taking part in a diabetes study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting diabetes studies in Pennsylvania.
Common questions
- Are there diabetes clinical trials near Philadelphia?
- Yes. We're currently tracking 60 recruiting diabetes studies with a site near Philadelphia, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a diabetes study near Philadelphia?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Philadelphia to take part?
- Not necessarily. These studies have a site near Philadelphia, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a diabetes trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New diabetes studies open near Philadelphia regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.