Clinical trials · California
Diabetes clinical trials in California
We’re tracking 187 recruiting diabetes studies with a site in California — including Phase 1, Phase 1/Phase 2, Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in California
- NCT07209475RecruitingPhase 4
Amnio-Maxx for healing diabetic foot ulcers
This trial tests whether a special wound dressing called Amnio-Maxx can help heal foot ulcers in people with diabetes. You may qualify if you have a diabetic foot ulcer that hasn't healed much with standard care.
Burbank, CaliforniaAges 18 years+ - NCT07187531RecruitingPhase 2
Testing a new drug to preserve insulin production in type 1 diabetes
This study tests a new drug called SAB-142, which aims to stop the immune system from attacking insulin-making cells in type 1 diabetes. It may help preserve your body's ability to make insulin. The trial will check if the drug is safe and effective.
San Francisco, CaliforniaAges 5–40 - NCT06525259Recruiting
Study on risk factors for type 2 diabetes in youth
This study looks for children and teens who are at high risk of developing type 2 diabetes to understand what factors lead to it. If your child is overweight, has slightly high blood sugar, and is in early to mid-puberty, they may be able to join.
Los Angeles, CaliforniaAges 8–15 - NCT07561541RecruitingPhase 4
Extended Antibiotics for Diabetic Leg Fracture Surgery
This study tests whether taking antibiotics for a longer time helps prevent infections in people with poorly controlled diabetes who need surgery for a lower leg or foot fracture. Since diabetes makes infections more likely after surgery, extra antibiotics might reduce that risk.
Los Angeles, CaliforniaAges 18 years+ - NCT07088068RecruitingPhase 3
Teplizumab for newly diagnosed type 1 diabetes
This study tests whether teplizumab can help keep the body making insulin in people recently diagnosed with type 1 diabetes. It is for children and young adults aged 1 to 25, and compares the drug against a placebo.
San Diego, CaliforniaAges 1–25 - NCT07065721Recruiting
Continuous glucose monitors for young adults with type 2 diabetes
This trial tests if using a continuous glucose monitor (a small sensor that checks your sugar levels without fingersticks) helps young adults manage type 2 diabetes better. You will wear the sensor and use a phone app to track your glucose.
San Diego, CaliforniaAges 18–45 - NCT07064473RecruitingPhase 3
Testing vicadrostat plus empagliflozin for diabetes, high blood pressure, and heart disease
This study tests a new pill called vicadrostat taken with another medicine (empagliflozin) to see if it helps people with type 2 diabetes, high blood pressure, and heart disease. It may reduce the risk of heart problems, but you must not have had heart failure or use certain other heart medications.
Beverly Hills, CaliforniaAges 18 years+ - NCT07061574RecruitingPhase 1/Phase 2
Immune treatment for new onset type 1 diabetes
This study tests a low dose of a drug that calms the immune system, followed by either another immune drug or a blood pressure medicine, to see if they can help preserve the body's ability to make insulin in people recently diagnosed with type 1 diabetes. It may help keep your own insulin production going longer.
San Francisco, CaliforniaAges 9–20 - NCT06999356Recruiting
Salud Diabetes: Lifestyle Changes and Glucose Monitoring Study
This study tests if combining lifestyle coaching with a continuous glucose monitor (CGM) helps people with type 2 diabetes improve their blood sugar control. You'll track your glucose levels using a study device and see how daily habits affect them.
Santa Barbara, CaliforniaAges 18–89 - NCT06981234RecruitingPhase 2
Acetazolamide for type 1 diabetes
This trial tests whether a medicine called acetazolamide (used for altitude sickness) can help people with type 1 diabetes. It compares how your body responds while on the drug versus a placebo, using a crossover design so everyone gets both treatments.
La Jolla, CaliforniaAges 18 years+ - NCT06964087RecruitingPhase 2
Testing OPT101 for type 1 diabetes
This trial tests an investigational drug called OPT101 in people with type 1 diabetes. It aims to see how the drug works in the body and whether it can help preserve insulin production, especially in those diagnosed recently or within the last 20 years.
Walnut Creek, CaliforniaAges 18–50 - NCT06923046Recruiting
Team Clinic for teens with type 2 diabetes
This trial tests a group clinic program for teens with type 2 diabetes. It aims to help you manage your diabetes better with support from others your age and your family.
Los Angeles, CaliforniaAges 12–18 - NCT06919354RecruitingPhase 1
Study of GNTI-122 for new type 1 diabetes
This study tests a new treatment called GNTI-122 for adults recently diagnosed with type 1 diabetes who still make some insulin. It aims to see if the treatment can help protect the cells that produce insulin.
San Diego, CaliforniaAges 18–55 - NCT06897475RecruitingPhase 2
Study of LY3457263 for type 2 diabetes on semaglutide or tirzepatide
This study tests if adding LY3457263 helps lower blood sugar in people with type 2 diabetes who are already taking a stable dose of semaglutide or tirzepatide. You will be randomly assigned to get either LY3457263 or a placebo.
Santa Ana, CaliforniaAges 18–75 - NCT06883344Recruiting
Automated insulin for managing blood sugar during labor
This study tests if an automated insulin delivery system can help manage blood sugar levels during labor and delivery in pregnant women with type 1 diabetes. If successful, it could make the process safer and easier.
Los Angeles, CaliforniaAges 18–55 - NCT06619860RecruitingPhase 2
VX-993 for diabetic nerve pain
This trial tests a new medicine called VX-993 for people with diabetes who have had nerve pain in both feet or legs for at least a year. The goal is to see if it reduces pain and is safe.
Bakersfield, CaliforniaAges 18–80 - NCT06860516Recruiting
HLA Demographics Study in Adults With Type 1 Diabetes
This study (NCT06860516) is an observational trial of adults aged 18-55 with type 1 diabetes diagnosed within 6 months. It aims to collect demographic and HLA data.
San Francisco, CaliforniaAges 18–55 - NCT06837181Recruiting
Understanding diabetes complications in cystic fibrosis
This study looks at how long-term diabetes affects people with cystic fibrosis. It helps researchers understand complications and improve care.
Los Angeles, CaliforniaAges 12 years+ - NCT06739122RecruitingPhase 3
A study of dulaglutide for children with type 2 diabetes
This trial tests if a weekly injection of dulaglutide (Trulicity) can help children with type 2 diabetes control their blood sugar when used together with metformin and/or insulin. It may be an option for kids who are overweight.
Los Angeles, CaliforniaAges 10–17 - NCT06681428Recruiting
Amniotic tissue treatment for diabetic foot ulcers
This trial tests whether an amniotic tissue treatment can help heal chronic diabetic foot ulcers that haven't improved with standard care. It focuses on a single ulcer below the ankle that has been present for more than 4 weeks but less than a year.
Fresno, CaliforniaAges 18 years+ - NCT06662994RecruitingPhase 4
High dose aflibercept for diabetic macular edema after vitrectomy
This trial tests a high-dose version of the drug aflibercept (given as an eye injection) for people with diabetic macular edema who have previously had a vitrectomy surgery. The goal is to see if this higher dose can help reduce swelling and improve vision.
Fullerton, CaliforniaAges 21 years+ - NCT06654713Recruiting
Closed-loop insulin system impact on pregnancy study
This study looks at how automated insulin delivery systems (closed-loop pumps) work during pregnancy for women with type 1 diabetes. It aims to understand how these systems can help manage blood sugar levels safely for both you and your baby.
San Francisco, CaliforniaAges 18 years+ - NCT06628453Recruiting
Continuous glucose monitor for type 2 diabetes in pregnancy
This study tests whether using a CGM (a small sensor that tracks blood sugar) can help manage type 2 diabetes during pregnancy better than standard care. It is for women who have type 2 diabetes and are pregnant with one baby.
San Diego, CaliforniaAges 18–50 - NCT06628908RecruitingPhase 3
Study of suzetrigine for painful diabetic nerve damage
This trial tests an experimental medicine called suzetrigine to see if it can safely reduce pain caused by nerve damage from diabetes (diabetic peripheral neuropathy). It might be an option if you have had daily pain in both legs and current treatments haven't worked well enough.
Fresno, CaliforniaAges 18–80
Diabetes trials by city in California
Where these studies are running in California
Institutions with a site for the recruiting diabetes studies listed above.
- University of California, San Francisco · 7 studies
- Children's Hospital Los Angeles · 2 studies
- Empire Clinical Research · 2 studies
- University of California San Diego · 2 studies
- Acclaim Clinical Research
- Angel City Research
- Angel City Research, Inc
- Ark Clinical Research
What taking part in a diabetes study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Diabetes trials in other states
Common questions
- Are there diabetes clinical trials in California?
- Yes. We're currently tracking 187 recruiting diabetes studies with a site in California, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a diabetes study in California?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in California to take part?
- Not necessarily. These studies have a site in California, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a diabetes trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New diabetes studies open in California regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.