Clinical trials · North Carolina
Diabetes clinical trials in North Carolina
We’re tracking 98 recruiting diabetes studies with a site in North Carolina — including Phase 1, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in North Carolina
- NCT06739122RecruitingPhase 3
A study of dulaglutide for children with type 2 diabetes
This trial tests if a weekly injection of dulaglutide (Trulicity) can help children with type 2 diabetes control their blood sugar when used together with metformin and/or insulin. It may be an option for kids who are overweight.
Chapel Hill, North CarolinaAges 10–17 - NCT06837181Recruiting
Understanding diabetes complications in cystic fibrosis
This study looks at how long-term diabetes affects people with cystic fibrosis. It helps researchers understand complications and improve care.
Winston-Salem, North CarolinaAges 12 years+ - NCT06852976RecruitingPhase 2
Gel treatment for diabetic foot ulcers study
This trial tests a new gel (MDI-1228-mesylate) applied to diabetic foot ulcers to see if it helps them heal faster than standard care alone. It is for people who have had a foot ulcer for at least 12 weeks and are already receiving standard treatment.
Durham, North CarolinaAges 18–75 - NCT06860516Recruiting
HLA Demographics Study in Adults With Type 1 Diabetes
This study (NCT06860516) is an observational trial of adults aged 18-55 with type 1 diabetes diagnosed within 6 months. It aims to collect demographic and HLA data.
Chapel Hill, North CarolinaAges 18–55 - NCT06897475RecruitingPhase 2
Study of LY3457263 for type 2 diabetes on semaglutide or tirzepatide
This study tests if adding LY3457263 helps lower blood sugar in people with type 2 diabetes who are already taking a stable dose of semaglutide or tirzepatide. You will be randomly assigned to get either LY3457263 or a placebo.
Morehead City, North CarolinaAges 18–75 - NCT06906627Recruiting
Improving kidney screening for people with diabetes
This study helps people with type 2 diabetes get the right kidney tests to catch kidney problems early. Your doctor will check your kidney health through a simple blood and urine test.
Houston, North CarolinaAges 18 years+ - NCT06906640Recruiting
Improving Kidney Care for People with Type 2 Diabetes
This study tests a program to help primary care doctors better screen and manage kidney problems in people with type 2 diabetes. It aims to see if using recommended medicines can slow kidney disease and improve health.
Durham, North CarolinaAges 18 years+ - NCT06919354RecruitingPhase 1
Study of GNTI-122 for new type 1 diabetes
This study tests a new treatment called GNTI-122 for adults recently diagnosed with type 1 diabetes who still make some insulin. It aims to see if the treatment can help protect the cells that produce insulin.
Chapel Hill, North CarolinaAges 18–55 - NCT07116876Recruiting
Placental membrane vs standard care for diabetic foot ulcers
This study tests a special wound covering made from donated placental tissue to see if it helps diabetic foot ulcers heal better than usual care. It may be an option for people with diabetes who have a foot sore that hasn't healed after 30 days.
Raleigh, North CarolinaAges 21–80 - NCT07187531RecruitingPhase 2
Testing a new drug to slow type 1 diabetes progression
This trial tests an experimental drug called SAB-142 to see if it can slow down or stop the progression of type 1 diabetes. It is designed for people who were recently diagnosed and still produce some insulin on their own.
Asheville, North CarolinaAges 5–40 - NCT07219602RecruitingPhase 3
Study of obicetrapib and ezetimibe for diabetes and metabolic syndrome
This trial tests a combination medication (obicetrapib plus ezetimibe) taken daily to lower cholesterol and triglycerides in people with type 2 diabetes or metabolic syndrome who are already on standard cholesterol treatment. It may help reduce heart risks.
Durham, North CarolinaAges 18 years+ - NCT07296484RecruitingPhase 2
Clofutriben for hard-to-control type 2 diabetes
This trial tests a new medication, clofutriben, for people with hard-to-control type 2 diabetes who might also have mild excess of a stress hormone called cortisol. It aims to see if the drug can help lower blood sugar and improve diabetes management.
Wilmington, North CarolinaAges 18 years+ - NCT07355270Recruiting
Radiofrequency vapor ablation for type 2 diabetes
This trial tests a new device that uses radiofrequency energy to treat the lining of the upper small intestine in people with type 2 diabetes. The goal is to see if this treatment is safe and helps improve blood sugar control.
Chapel Hill, North CarolinaAges 22–65 - NCT07415954RecruitingPhase 2
Testing a new diabetes medicine for blood sugar control
This study tests a new medicine, NNC0662-0419, in people with type 2 diabetes. You must be willing to lose a lot of weight (more than a quarter of your current weight) as part of the study to see if the medicine helps lower blood sugar.
Greensboro, North CarolinaAges 18–75 - NCT07076199RecruitingPhase 3
Weekly vs daily insulin for type 1 diabetes
This study tests a new once-weekly insulin (icodec) against a standard daily insulin (glargine), both taken with mealtime insulin. It aims to see which works better to control blood sugar in adults with type 1 diabetes.
Greenville, North CarolinaAges 18 years+ - NCT07564414RecruitingPhase 3
Weight Loss Study Comparing Two Doses of CagriSema
This study tests whether a new combination medication called CagriSema (in two different doses) helps people with obesity lose weight. You may qualify if you're 18 or older, have a BMI of 35 or higher, and either don't have type 2 diabetes or have it well-controlled.
Greensboro, North CarolinaAges 18 years+ - NCT06598345Enrolling by invitation
Pet fish care for better diabetes management in teens
This study tests if taking care of a pet fish can help kids aged 10-13 with type 1 diabetes improve their blood sugar control and take more responsibility for their diabetes care.
Durham, North CarolinaAges 10–13 - NCT06962839RecruitingPhase 2
Study of BI 1815368 for diabetic macular edema
This trial tests an experimental medication (BI 1815368) given as an eye injection for people with diabetic macular edema, a condition where fluid builds up in the center of the retina and blurs vision. The study aims to see if this new treatment can reduce swelling and improve vision.
Wake Forest, North CarolinaAges 18 years+ - NCT06790784RecruitingPhase 3
Comparing faricimab plus laser vs. surgery for diabetic eye disease
This study compares two approaches to treat advanced diabetic eye disease (proliferative diabetic retinopathy): injections of faricimab plus laser, versus surgery (vitrectomy) with laser. It is for people with diabetes who need treatment for PDR and still have relatively good vision (20/100 or better) in the affected eye.
Chapel Hill, North CarolinaAges 18 years+ - NCT06616844Recruiting
Patch for non-healing diabetic foot ulcers
This trial tests a special patch made from pig tissue (placenta) placed on diabetic foot ulcers that are not healing well. If you have a foot ulcer that has been present for 4 to 52 weeks and is not shrinking, you may be able to join the study.
Raleigh, North CarolinaAges 18 years+ - NCT06010433Recruiting
CERAMENT G treatment tracking study
This study tracks how well the CERAMENT G device works for people getting it as part of their treatment. It helps doctors gather real-world safety and effectiveness information.
Charlotte, North CarolinaAges 18 years+ - NCT07221045Recruiting
Food as medicine for food-insecure families in rural North Carolina
This study tests whether providing fresh produce boxes and nutrition classes helps families in rural North Carolina who struggle with food access. If you are a parent or caregiver of an 8–14-year-old and live in a participating county, you may qualify.
Raleigh, North CarolinaAges 8–64 - NCT07413874Recruiting
Music therapy over video for depression and hormone disorder
This trial tests if telehealth music therapy can help adults who have both an endocrine autoimmune disease and depression. You'll join sessions from home using Zoom.
Boone, North CarolinaAges 18–65 - NCT07284979RecruitingPhase 3
Weekly injection for obesity without diabetes
This trial tests a new once-weekly injection called Ribupatide for weight loss in people with obesity who do not have diabetes. It compares the study drug to an existing medication (semaglutide) and a placebo to see how well it works and if it's safe.
Morehead City, North CarolinaAges 18 years+
Diabetes trials by city in North Carolina
Where these studies are running in North Carolina
Institutions with a site for the recruiting diabetes studies listed above.
- University of North Carolina at Chapel Hill · 5 studies
- Duke University · 4 studies
- Centricity Research · 3 studies
- Physicians East · 3 studies
- Accellacare · 2 studies
- Lucas Research · 2 studies
- PharmQuest Life Sciences LLC · 2 studies
- Piedmont Healthcare · 2 studies
What taking part in a diabetes study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Diabetes trials in other states
Common questions
- Are there diabetes clinical trials in North Carolina?
- Yes. We're currently tracking 98 recruiting diabetes studies with a site in North Carolina, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a diabetes study in North Carolina?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in North Carolina to take part?
- Not necessarily. These studies have a site in North Carolina, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a diabetes trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New diabetes studies open in North Carolina regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.