Clinical trials · North Carolina
Diabetes clinical trials in North Carolina
We’re tracking 95 recruiting diabetes studies with a site in North Carolina — including Phase 1, Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in North Carolina
- NCT02915198RecruitingPhase 4
Metformin for prediabetes to reduce heart and blood-vessel events
This trial tests whether taking metformin in people with prediabetes can lower the chance of future heart attack, stroke, or other blood-vessel problems. You may be a good fit if you have prediabetes plus existing cardiovascular disease or significant blood-vessel disease.
Durham, North CarolinaAges 18 years+ - NCT06962839RecruitingPhase 2
Study of BI 1815368 for diabetic macular edema
This trial tests an experimental medication (BI 1815368) given as an eye injection for people with diabetic macular edema, a condition where fluid builds up in the center of the retina and blurs vision. The study aims to see if this new treatment can reduce swelling and improve vision.
Wake Forest, North CarolinaAges 18 years+ - NCT07224334RecruitingPhase 1
How cells talk to adjust insulin for weight
This study looks at how cells in the pancreas communicate to help the body produce enough insulin when you have insulin resistance (weight-related). It tests a peptide to see how this communication works.
Durham, North CarolinaAges 18–60 - NCT00341237Recruiting
Study linking genes and environment to health risks
This study looks at how your genes and your environment may affect your health. It may help researchers better understand who is most at risk so future prevention and care can be more personalized.
Research Triangle Park, North CarolinaAges 18–120 - NCT06616844Recruiting
Patch for non-healing diabetic foot ulcers
This trial tests a special patch made from pig tissue (placenta) placed on diabetic foot ulcers that are not healing well. If you have a foot ulcer that has been present for 4 to 52 weeks and is not shrinking, you may be able to join the study.
Raleigh, North CarolinaAges 18 years+ - NCT06790784RecruitingPhase 3
Comparing faricimab plus laser vs. surgery for diabetic eye disease
This study compares two approaches to treat advanced diabetic eye disease (proliferative diabetic retinopathy): injections of faricimab plus laser, versus surgery (vitrectomy) with laser. It is for people with diabetes who need treatment for PDR and still have relatively good vision (20/100 or better) in the affected eye.
Chapel Hill, North CarolinaAges 18 years+ - NCT06010433Recruiting
CERAMENT G treatment tracking study
This study tracks how well the CERAMENT G device works for people getting it as part of their treatment. It helps doctors gather real-world safety and effectiveness information.
Charlotte, North CarolinaAges 18 years+ - NCT07784725RecruitingPhase 3
Study of a weight loss injection for adults with obesity
This study tests a new medicine to help adults with obesity or overweight lose weight. It's for people who have had trouble losing weight in the past and don't have diabetes.
Statesville, North CarolinaAges 18 years+ - NCT07413874Recruiting
Music therapy over video for depression and hormone disorder
This trial tests if telehealth music therapy can help adults who have both an endocrine autoimmune disease and depression. You'll join sessions from home using Zoom.
Boone, North CarolinaAges 18–65 - NCT07361341Recruiting
Food support program for adults with diabetes or prediabetes
This trial tests a culturally tailored food bundle program for people with type 2 diabetes or very high prediabetes who also face food insecurity. If you qualify, you may receive free food bundles and help managing your health.
Winston-Salem, North CarolinaAges 18 years+ - NCT07332416Enrolling by invitation
Glucose monitor for postpartum diabetes screening
This study tests if a continuous glucose monitor can help screen for diabetes after pregnancy in people who had gestational diabetes. It aims to make screening easier and more comfortable than the traditional glucose drink test.
Winston-Salem, North CarolinaAges 18 years+ - NCT07284979RecruitingPhase 3
Weekly injection for obesity without diabetes
This trial tests a new once-weekly injection called Ribupatide for weight loss in people with obesity who do not have diabetes. It compares the study drug to an existing medication (semaglutide) and a placebo to see how well it works and if it's safe.
Morehead City, North CarolinaAges 18 years+ - NCT07222293Recruiting
Testing an AI tool to screen for diabetic eye disease
This study uses an AI program called DRISTi to screen for diabetic eye disease by taking pictures of the back of your eye. It's designed for adults with diabetes who haven't had major eye treatments or vision loss.
Oxford, North CarolinaAges 21 years+ - NCT07221045Recruiting
Food as medicine for food-insecure families in rural North Carolina
This study tests whether providing fresh produce boxes and nutrition classes helps families in rural North Carolina who struggle with food access. If you are a parent or caregiver of an 8–14-year-old and live in a participating county, you may qualify.
Raleigh, North CarolinaAges 8–64 - NCT07172893RecruitingPhase 4
Dermabind TL for diabetic foot ulcers
This trial tests a new wound dressing called DermaBind TL for people with diabetic foot ulcers. It aims to see if the dressing helps heal these wounds, which can be hard to treat.
Cary, North CarolinaAges 18–80 - NCT06907147Recruiting
Renal denervation for uncontrolled high blood pressure
This trial tests a procedure called renal denervation to lower blood pressure in people whose medication isn't enough. It uses a special catheter to calm nerves near the kidneys that may be overactive.
Chapel Hill, North CarolinaAges 18–80 - NCT06384183Enrolling by invitation
Real-world fish skin graft registry study
This study tracks how well a fish skin graft (Kerecis) heals wounds in real patients. It helps doctors learn more about who benefits most from this treatment.
Greensboro, North CarolinaAges Any age - NCT06368817RecruitingPhase 2
Lower radiation dose for children with CNS germinoma
This trial will see if giving a lower dose of radiation therapy can still effectively treat children and young adults with a type of brain tumor called germinoma. The goal is to reduce side effects while keeping the cancer under control.
Chapel Hill, North CarolinaAges 3–29 - NCT06190717Recruiting
Ultrasound implant to help dialysis fistula mature
This study tests whether a special ultrasound implant (EchoMark) helps a new dialysis fistula mature properly. It involves people with advanced kidney disease who are starting or already on dialysis and are having a fistula created in the upper arm.
Concord, North CarolinaAges 18–84 - NCT05674799Recruiting
Program to lower future obesity and diabetes risks
This trial tests a lifestyle and coaching program (NDPP-NextGen) to help reduce the chances of obesity and diabetes risk passing to the next generation. It’s for people planning a pregnancy soon and who may be at higher risk due to body weight.
Winston-Salem, North CarolinaAges 18–39 - NCT05129345Recruiting
HIV care program for heart health goals in the Southeast US
This trial tests an approach to help people living with HIV reach heart- and metabolism-related health goals, such as blood pressure, cholesterol, and blood sugar. It involves clinics and community partners and may offer education, support, and care coordination to remove barriers to treatment.
Charlotte, North CarolinaAges 18 years+ - NCT04943861Recruiting
Study on HIV and food insecurity support
This study is looking at food insecurity in adults living with HIV. It may help improve understanding of the barriers to healthy living and guide better support for people affected by HIV.
Winston-Salem, North CarolinaAges 18 years+ - NCT04661215Recruiting
Testing stomach opening muscle problems in people with gastroparesis
This study looks at whether abnormal function of the pyloric “stomach outlet” muscle is linked to gastroparesis symptoms (slow stomach emptying). It may help researchers better understand what causes symptoms and guide future treatments.
Winston-Salem, North CarolinaAges 18–85
Diabetes trials by city in North Carolina
Where these studies are running in North Carolina
Institutions with a site for the recruiting diabetes studies listed above.
- Wake Forest University Health Sciences · 5 studies
- Appalachian State University
- Atrium Health
- Cone Health Ortho Care Greensboro
- Duke Center for Living
- Duke University - Charlotte Study Sites
- Duke University - Duke Study Site
- Durham VA Medical Center, Durham, NC
What taking part in a diabetes study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Diabetes trials in other states
Common questions
- Are there diabetes clinical trials in North Carolina?
- Yes. We're currently tracking 95 recruiting diabetes studies with a site in North Carolina, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a diabetes study in North Carolina?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in North Carolina to take part?
- Not necessarily. These studies have a site in North Carolina, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a diabetes trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New diabetes studies open in North Carolina regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.