Clinical trials · Denver, CO
Down Syndrome clinical trials in Denver
We’re tracking 92 recruiting down syndrome studies with a site in or near Denver — including Phase 1, Phase 2, Phase 2/Phase 3 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies near Denver
- NCT05432349Recruiting
Rett syndrome genetic registry for MECP2 changes
This trial is a registry that collects health and genetic information from people with Rett syndrome. It may help researchers better understand how MECP2 loss-of-function changes lead to symptoms and how to support patients.
Denver, ColoradoAges birth–99 years - NCT04546399RecruitingPhase 2
Blinatumomab with or without nivolumab for first relapse ALL
This study compares blinatumomab alone versus blinatumomab plus nivolumab in young people whose B-cell ALL has returned for the first time. It aims to see whether adding nivolumab improves control of the leukemia after relapse.
Denver, ColoradoAges 1–30 - NCT05701917Recruiting
Clot-busting device versus blood thinners for leg clot
This study compares a clot-removal device (ClotTriever) plus standard care versus standard blood thinners alone for a deep vein clot in the leg. It aims to see which approach better improves leg symptoms and outcomes.
Denver, ColoradoAges 18 years+ - NCT07498426RecruitingPhase 3
Study of NIO752 for progressive supranuclear palsy
This trial tests a new medicine called NIO752 for people with progressive supranuclear palsy (PSP), a condition that affects movement, balance, and thinking. The goal is to see if it can help slow the disease's progression.
Englewood, ColoradoAges 41–81 - NCT01950624Recruiting
DS-Connect registry for people with Down syndrome
This is a study registry that collects information from people with Down syndrome (or certain forms like mosaic or partial trisomy 21) and their families. It helps researchers learn about health and needs over time and makes it easier to contact people for future studies.
Aurora, ColoradoAges Any age - NCT01209000Recruiting
Study for children with new kidney protein loss
This study is for children (and some newly diagnosed patients) who have nephrotic syndrome—kidneys leaking a lot of protein. It aims to better understand the kidney condition (sometimes using biopsy) and support future care decisions.
Aurora, ColoradoAges Up to 80 years - NCT07579429RecruitingPhase 2
Nicotinamide Riboside Supplement for MDS
This trial tests whether a supplement called nicotinamide riboside can help people with a blood disorder called MDS (myelodysplastic syndrome) or early warning signs of it. The supplement is meant to support your bone marrow's ability to make healthy blood cells.
Aurora, ColoradoAges 18 years+ - NCT07444567RecruitingPhase 3
Continuing benralizumab treatment after a previous study
This trial lets people who completed an earlier benralizumab study and are benefiting from the medicine keep receiving it. The goal is to provide ongoing access while we continue to monitor safety and effectiveness.
Aurora, ColoradoAges 6 years+ - NCT03396562Recruiting
Study of early development in babies with extra sex chromosomes
This study follows infants and young children with conditions caused by having an extra sex chromosome (like XXY, XYY, or XXX) to learn how health and development unfold over time. It may help families and doctors understand what to expect and what support could be helpful.
Aurora, ColoradoAges 1 month–1.1 years - NCT07450664Enrolling by invitation
Observational study of VYKAT XR for Prader-Willi syndrome
This study follows people with Prader-Willi syndrome who are already taking or starting VYKAT XR, including those switching from an earlier version of the drug (DCCR). It aims to understand how the treatment works in everyday life.
Aurora, ColoradoAges 4 years+ - NCT07519395RecruitingPhase 2
Camlipixant for IBS with diarrhea or mixed symptoms
This study tests an investigational drug, camlipixant, to see if it can reduce belly pain and diarrhea or mixed bowel symptoms in adults with irritable bowel syndrome (IBS). If you've tried other IBS treatments without enough relief, this might be an option.
Aurora, ColoradoAges 18–80 - NCT06366464RecruitingPhase 3
Study of a drug for sleepiness in Prader-Willi syndrome
This trial tests a medication called pitolisant to see if it helps reduce excessive daytime sleepiness in people with Prader-Willi syndrome. You or your loved one may be able to join if they have a confirmed diagnosis and a caregiver who can regularly help with study tasks.
Aurora, ColoradoAges 6 years+ - NCT06414096RecruitingPhase 1
Pulsatile FSH study for women with obesity or low ovarian reserve
This study tests a new way to give a fertility hormone (FSH) in pulses through a small tube to see if it helps women with obesity or low egg reserve have better egg development with fewer health risks. It may improve fertility treatment outcomes for these women.
Aurora, ColoradoAges 19–37 - NCT01522183Recruiting
Registry for people with atypical hemolytic uremic syndrome
This is a registry that collects information from people diagnosed with atypical hemolytic uremic syndrome (aHUS). It helps researchers better understand the condition across different genetic causes and treatment needs.
Aurora, ColoradoAges Any age - NCT06428019RecruitingPhase 3
Comparing drug combinations for untreated CLL or SLL
This trial tests two different drug combinations (venetoclax with obinutuzumab or with acalabrutinib) to see how they affect the risk of tumor lysis syndrome in people with untreated CLL or SLL. It may help find the safest and most effective way to start treatment.
Aurora, ColoradoAges 18 years+ - NCT05292664RecruitingPhase 1
Venetoclax trial for high-risk blood cancers in young patients
This Phase 1 study tests venetoclax to treat certain high-risk blood cancers in children, teens, or young adults. It is designed to see if the drug can work safely for patients whose disease has returned or did not respond to prior treatment.
Aurora, ColoradoAges 1–40 - NCT04507997Recruiting
Study of the natural course of Angelman syndrome
This study follows people with Angelman syndrome to understand how their symptoms and development change over time. It may help researchers better describe the condition and support future treatments.
Aurora, ColoradoAges Any age - NCT07020819RecruitingPhase 3
Study of tanruprubart for people with Guillain-Barré syndrome
This trial tests a new medicine, tanruprubart (also called ANX005), for people with Guillain-Barré syndrome. It aims to see if the drug can help improve recovery when given soon after symptoms start.
Aurora, ColoradoAges 12–85 - NCT06582914Recruiting
Lynch syndrome genetics and health study
This study looks at the genetics and health of people with Lynch syndrome, a condition that raises the risk for certain cancers. Researchers want to learn more about how different genetic changes affect health over time.
Aurora, ColoradoAges 18 years+ - NCT07598643RecruitingPhase 2
Study of tofacitinib for immune function in Down syndrome
This study tests if an oral medication called tofacitinib can help the immune system work better in children and young adults with Down syndrome, which may improve learning and development. The study will follow participants for 6 months.
Aurora, ColoradoAges 6–22 - NCT06154252RecruitingPhase 2/Phase 3
Study of CABA-201 for active myositis in adults and children
This trial tests a new treatment called CABA-201, which uses your own immune cells modified to attack the overactive cells causing myositis. It is for people with active disease that hasn't improved enough with standard therapies.
Aurora, ColoradoAges 6–75 - NCT07221851RecruitingPhase 3
Weekly vs daily growth hormone for short stature in children
This trial tests a weekly growth hormone injection (lonapegsomatropin) compared to the standard daily growth hormone shot in children with short stature due to certain conditions. It aims to see if the weekly shot works as well or better and is safe.
Aurora, ColoradoAges 2–17 - NCT07238465RecruitingPhase 3
Nervous system and heart function in Down syndrome
This study looks at how the nervous system controls heart rate and blood pressure in adults with Down syndrome. It involves some simple tests, like blood draws and placing a small tube in an arm vein, plus possibly some cold water or exercise tasks.
Aurora, ColoradoAges 18–50 - NCT03949855RecruitingPhase 2
Belimumab plus rituximab for primary membranous nephropathy
This study tests whether adding belimumab to rituximab helps people with primary membranous nephropathy (a kidney disease) that has the right blood test marker and specific protein levels. The goal is to improve kidney outcomes and reduce disease activity while keeping treatment safe.
Aurora, ColoradoAges 18–75
Hear when a new Down Syndrome trial opens near Denver, CO
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Down Syndrome trials in other cities
Where these studies are running near Denver
Institutions with a site for the recruiting down syndrome studies listed above.
- Children's Hospital Colorado · 5 studies
- University of Colorado · 2 studies
- University of Colorado Anschutz Medical Campus · 2 studies
- University of Colorado Hospital · 2 studies
- Ascendis Pharma Investigational Site
- CenExel Rocky Mountain Clinical Research
- Children's Hospital Colorado - Accepting Juvenile Patients
- Children's Hospital Colorado, Anschutz Medical Campus
What taking part in a down syndrome study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting down syndrome studies in Colorado.
Common questions
- Are there down syndrome clinical trials near Denver?
- Yes. We're currently tracking 92 recruiting down syndrome studies with a site near Denver, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a down syndrome study near Denver?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Denver to take part?
- Not necessarily. These studies have a site near Denver, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New down syndrome studies open near Denver regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.