Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,055 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06957873Recruiting
Skull and Neck Angle in Fibromyalgia
This study looks at how the angle of your skull and neck relates to fibromyalgia pain. It may help researchers understand why some people have more severe symptoms.
Ankara, AltindagAges 18–55 - NCT06961136Recruiting
Herbal medicine for recovery after heart bypass surgery
This trial tests if a traditional Chinese herbal formula (Fuzheng Yangxin Prescription) can help people recover faster after coronary artery bypass surgery. It is for people who have a specific pattern of symptoms (called Qi-Yin deficiency) after their operation.
Beijing, Beijing MunicipalityAges 25–85 - NCT06960993Recruiting
Mosaic trial for stem cell transplant patients
This trial tests a website designed to help patients learn about stem cell transplants for blood cancers. It aims to support you during your transplant journey.
Washington D.C., District of ColumbiaAges 18 years+ - NCT06952907Recruiting
Arm vs. leg artery pressure monitoring in heart surgery
This study compares measuring blood pressure through an arm artery (radial) versus a leg artery (femoral) during heart surgery that uses a heart-lung machine. The goal is to see which method works better and is safer for patients.
BesançonAges 18 years+ - NCT06947473RecruitingPhase 1/Phase 2
CAR T-cell therapy for lupus, sclerosis, and Sjogren's
This trial tests a new type of immune cell therapy (CAR T-cells from umbilical cord blood) for people with certain autoimmune diseases that haven't responded to standard treatments. It aims to see if targeting two proteins (CD19 and BCMA) can help calm the overactive immune system.
Beijing, Beijing MunicipalityAges 6–65 - NCT06947460RecruitingPhase 1/Phase 2
CAR-T cell therapy for resistant lupus, sclerosis, and Sjögren's lung disease
This trial tests a special immune cell therapy (CAR-T cells targeting CD19 and BCMA) for people with lupus nephritis, systemic sclerosis, or Sjögren's-related lung blood vessel disease that hasn't improved with usual treatments. The goal is to see if this one-time cell infusion can calm the overactive immune system and improve symptoms.
Beijing, China,BeijingAges 10–65 - NCT06944262Recruiting
Cancer-related stress study for patients and caregivers
This study looks at stress after a cancer diagnosis and asks patients and caregivers what kind of support they want. It may help improve care for people coping with cancer.
Lille, NordAges 18 years+ - NCT05885646Recruiting
Sulthiame study using sleep EEG in children with epilepsy
This trial tests whether sulthiame changes sleep-related brain wave activity (EEG) in children with certain epilepsy syndromes. It may help doctors understand how sulthiame affects the brain’s electrical patterns between seizures.
AngersAges 6–15 - NCT06321341RecruitingPhase 4
Testing Vespireit for chronic dizziness from autonomic dysfunction
This trial tests a new medication called Vespireit (prolonged-release buspirone) for people with chronic dizziness caused by a problem with the autonomic nervous system. The study aims to see if the drug helps reduce dizziness and improve quality of life.
BryanskAges 18–65 - NCT06625463Recruiting
Heart rehab at home with family support after a heart attack
This study tests a heart rehab program you can do at home, with help from your family. If you've had a heart attack in the past year and don't have other major health issues, this program might help you recover and stay healthy.
Sleman, Special Region of YogyakartaAges 18–65 - NCT06940323Recruiting
Pregnancy study for women with chronic conditions
This study tracks pregnant women with certain chronic health conditions (like multiple sclerosis, lupus, or rheumatoid arthritis) and healthy pregnant women as a comparison group. It aims to understand how these conditions and their treatments affect pregnancy, the baby, and breast milk.
San Francisco, CaliforniaAges 18–64 - NCT06938217Enrolling by invitation
Low-flow ECMO for adults with severe breathing failure
This study tests whether a gentler, low-blood-flow version of ECMO (a machine that helps oxygenate blood outside the body) is safe and effective for adults with very severe breathing failure. It is for patients who are already on a breathing machine and have very low oxygen levels despite that support.
San Antonio, TexasAges 18–65 - NCT06936774RecruitingPhase 3
Intensive follow-up after rectal cancer surgery to improve recovery
This study tests whether a more intensive follow-up program after rectal cancer surgery can improve your recovery, daily function, and overall quality of life. If you've had a temporary ileostomy and are waiting for reversal, this extra support may help you feel better faster.
BaselAges 18 years+ - NCT06933173Recruiting
Mind-body therapy for Long COVID and ME/CFS
This trial tests whether a specific mind-body program can help people with Long COVID or ME/CFS feel better. It compares the program to standard care to see if it improves symptoms like fatigue and brain fog.
Calgary, AlbertaAges 18 years+ - NCT05939739Recruiting
Testing genes in severe language and learning difficulties
This study uses a special DNA test (trio exome sequencing) on a child or young adult and their two biological parents to look for a genetic cause of language and learning difficulties. If a genetic reason is found, it may help explain the cause and guide future care.
DijonAges 3–40 - NCT05822869Recruiting
Testing early EIT monitoring in people with ARDS
This trial looks at monitoring people with ARDS (a serious lung condition) very early after breathing support starts, using a technology called EIT. The goal is to see whether this early monitoring can help guide care during the first critical hours.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06924086Recruiting
Adaptive deep brain stimulation for children with epilepsy
This trial tests a new type of brain stimulation (adaptive deep brain stimulation) that adjusts in real time to stop seizures in children with Lennox-Gastaut syndrome. It's for children who haven't gotten enough help from medications and have frequent drop seizures.
LondonAges 5–14 - NCT06923800Recruiting
Exercise and Diet Advice for Fibromyalgia and IBS
This study tests whether combining exercise with dietary advice can help people who have both fibromyalgia and irritable bowel syndrome (IBS). It aims to see if this approach improves symptoms and quality of life.
Castellana Grotte, BariAges 30–65 - NCT06927739RecruitingPhase 2
Orticumab for heart artery inflammation after a heart attack
This trial tests a drug called orticumab to see if it can reduce inflammation in the arteries of the heart after a heart attack. It may help prevent future heart problems.
Los Angeles, CaliforniaAges 18 years+ - NCT02852031Recruiting
Care program for newborns needing the Norwood procedure
This trial focuses on improving care for babies born with certain complex heart conditions where only one pumping chamber works. It is meant for babies (including unborn babies) who are planned to have the Norwood procedure, which is a common early surgery.
Birmingham, AlabamaAges Up to 1.3 years - NCT06668714Recruiting
Does lactate affect nutrient absorption and fat storage?
This study tests whether taking lactate (a natural substance) with a meal affects how your body absorbs nutrients and stores fat. It is for people with prediabetes who are not on glucose-lowering medication.
AarhusAges 50 years+ - NCT05780099Recruiting
Study of patients treated in internal medicine clinics
This observational study follows people receiving care in Internal Medicine at San Raffaele Hospital to better understand what kinds of conditions they have. It does not test a new treatment, but your information may help improve future care.
MilanAges 18 years+ - NCT06919484Recruiting
RCexp effect on lung air and blood flow in ARDS
This study tests a new technique (RCexp) to see how it affects air and blood flow in the lungs of people with ARDS who are on a breathing machine. It aims to improve how we monitor and treat lung problems.
Nanjing, JiangsuAges 19 years+ - NCT06917794Enrolling by invitation
Genetic risk study for colon cancer patients
This study looks at how your genetic background and ancestry affect your risk for colon cancer. If you have been diagnosed with colon cancer and have a tumor sample available, you may be able to help researchers develop better risk scores.
Fortaleza, CearáAges 18 years+
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,055 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.