Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,173 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06498297Recruiting
Reorientation Tool for Confusion in Older Hospitalized Patients
This study looks at whether a special tool that helps reorient patients in time and space can speed up recovery from confusion in older adults. It may help if you or a loved one have been in the hospital and experienced confusion.
StrasbourgAges 75 years+ - NCT06498973RecruitingPhase 1
Maintenance therapy after stem cell transplant for CD123-positive AML/MDS
This trial tests a combination of two drugs, tagraxofusp and azacitidine, given as maintenance therapy after a stem cell transplant. The goal is to prevent the leukemia or MDS from coming back in patients whose cancer cells carry a specific marker called CD123.
Duarte, CaliforniaAges 18–75 - NCT06502795Recruiting
Quad Strengthening for Knee Pain at Different Angles
This study tests whether strengthening your quadriceps (front thigh muscles) at different knee angles can reduce pain behind or around your kneecap. If you have had this type of knee pain for at least 3 months, you may be eligible.
Fortaleza, CearáAges 18–35 - NCT06502834RecruitingPhase 1
Testing a probiotic supplement for overweight people
This trial studies a supplement called D. piger to see if it's safe and how it affects alcohol breakdown in overweight adults with insulin resistance. You would take the supplement daily for 4 weeks.
AmsterdamAges 18–70 - NCT06504511Recruiting
SCN1A gene study for epilepsy patients in the UK
This study aims to better understand SCN1A-related epilepsies by following patients over time. Researchers hope to learn more about how the condition progresses to help develop future treatments.
GlasgowAges Any age - NCT06505512Recruiting
Belly infection and kidney health ultrasound study
This study uses ultrasound to look at your belly organs and kidney blood flow in people with serious belly infections and sepsis. It may help doctors understand how infection affects the kidneys.
Zhangzhou, FujianAges 14–85 - NCT06506708Recruiting
Massage and hydrotherapy for endometriosis pain
This study tests whether combining massage and water therapy can reduce pain and improve well-being in people with endometriosis. If you have had pelvic pain for at least 6 months, this trial might help you find relief.
GranadaAges 18–55 - NCT06508099RecruitingPhase 2
Vitamin A and D supplements after stem cell transplant
This trial tests whether taking vitamin A and D after a stem cell transplant can help improve recovery. It is for people with certain blood cancers who have a matched donor and are in remission or have low disease activity.
Saint PetersburgAges 18 years+ - NCT06511297Recruiting
How aging and weight affect health: a deep-dive study
This study looks at how aging and body weight affect health and metabolism. Researchers will collect detailed measurements (like scans and blood tests) to understand why some people age better than others. You may join if you are in one of five age/weight groups.
Vienna, State of ViennaAges 18 years+ - NCT06512168Recruiting
Measuring aided language development in children
This study tests whether using an iPad communication app helps children with Down syndrome or cerebral palsy who have trouble speaking. It looks at how their language skills grow over time.
Orlando, FloridaAges 3.5 years–5 years - NCT06512870Recruiting
Detecting perfusion problems in leg injuries
This trial tests two devices to see if they can quickly detect when a leg muscle is not getting enough blood after a serious leg injury.
Gainesville, FloridaAges 18–75 - NCT06517056Recruiting
3D Knee Assessment for Active Duty Knee Pain
This trial tests a 3D camera device that measures how your knee moves. It may help find the best way to treat your front-of-knee pain and keep you mission-ready.
Honolulu, HawaiiAges 18–50 - NCT06519656RecruitingPhase 1/Phase 2
Mazdutide for treating PCOS
This trial is testing a new medication called Mazdutide to help treat PCOS in women with obesity. It aims to see if it improves PCOS symptoms and related health issues.
ShanghaiAges 18–40 - NCT06521801Recruiting
The Heart-Kidney Health Registry Study
This is an observational registry that collects information from people with kidney disease who are seen by the kidney team at Royal London Hospital. It helps researchers study heart and kidney health over time without needing extra tests or visits.
LondonAges 16 years+ - NCT06523556RecruitingPhase 1/Phase 2
Axatilimab with or without azacitidine for advanced blood cancers
This trial tests a new drug, axatilimab, given alone or with another drug (azacitidine) for people with advanced forms of blood cancers like certain leukemias and myelofibrosis. It may help if your disease has not responded to earlier treatments or if you are starting treatment for the first time.
Columbus, OhioAges 18 years+ - NCT06523790Recruiting
How different exercises affect your body and metabolism
This study looks at how different types of exercise affect your body functions and metabolism over 8 months. It may help you learn what exercise works best for you.
Zhoukou, HenanAges 18–65 - NCT06525623Recruiting
Early albumin for kidney injury in cirrhosis
This study tests whether giving a common fluid (albumin) early can help protect the kidneys in people with advanced liver disease who have a sudden kidney injury. It aims to see if this simple treatment can improve recovery and prevent the need for dialysis.
Boston, MassachusettsAges 18 years+ - NCT06526533RecruitingPhase 3
Red blood cell transfusion thresholds for ECMO patients
This trial is testing whether a higher or lower threshold for red blood cell transfusions is better for people on ECMO (a heart-lung machine). It aims to find the safest way to manage transfusions during ECMO treatment.
Camperdown, New South WalesAges Any age - NCT06528639Recruiting
Exercise program to reduce heart and metabolic risk
This study tests whether a personalized exercise plan guided by a special breathing test can help lower your risk for heart disease and related conditions. You may qualify if you are not very active and have early signs of metabolic syndrome like a larger waist, higher blood sugar, or higher blood pressure.
Beijing, Beijing MunicipalityAges 30–65 - NCT06529744Recruiting
Using blood tests to better diagnose early dementia
This study is testing whether simple blood tests can help doctors better understand the type and progression of memory or thinking problems in people with early dementia. It aims to improve confidence in the diagnosis and future outlook.
North York, OntarioAges 30–95 - NCT06532084RecruitingPhase 2
Sorafenib to prevent relapse after stem cell transplant
This trial tests whether the drug sorafenib can prevent blood cancer from returning after a stem cell transplant. It is for people who had a special combination of chemotherapy (bendamustine and cyclophosphamide) during their transplant and are at high risk for relapse.
Saint PetersburgAges 18–75 - NCT06534723RecruitingPhase 3
Wujia Yizhi granules for mild-to-moderate Alzheimer's
This trial tests if a Chinese herbal granule (Wujia Yizhi) can help people with mild-to-moderate Alzheimer's dementia. It is for patients who have memory problems for at least 6 months and meet specific Alzheimer's biomarker criteria.
Fuzhou, FujianAges 50–80 - NCT06535568Recruiting
Comparing one vs two blood thinners after heart artery balloon treatment
This trial tests whether taking just one blood thinner (clopidogrel) is as safe and effective as taking two (clopidogrel plus aspirin) for older adults or people at high bleeding risk who have had a drug-coated balloon procedure to open blocked heart arteries.
Milan, MIAges Any age - NCT06536959RecruitingPhase 2
VA plus PD-1 inhibitor for relapsed AML and high-risk MDS
This trial tests a combination of two drugs—a chemotherapy-like agent called VA and a PD-1 inhibitor (which helps your immune system fight cancer)—for people with AML or high-risk MDS that has not responded to or returned after initial treatment. The goal is to see if this combination can work better than standard treatments alone.
Beijing, Beijing MunicipalityAges 18–70
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,173 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.