Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,173 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06566742RecruitingPhase 2
Olutasidenib for IDH1-mutated blood disorders
This trial tests an oral drug called olutasidenib in people with certain low-risk blood cancers or a pre-cancer condition. It may help by targeting a specific genetic change (IDH1 mutation) found in your blood cells.
Miami, FloridaAges 18 years+ - NCT06576323Recruiting
Support for mothers with opioid use disorder and babies in the NICU
This study aims to improve care for mothers with opioid use disorder and their babies with neonatal abstinence syndrome. Researchers will interview healthcare providers and mothers to develop better support programs.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05705804Recruiting
Comparing statins and ezetimibe for heart patients with metabolic syndrome
This trial tests if pitavastatin alone or with ezetimibe affects blood sugar differently than atorvastatin in people who have heart or blood vessel disease and metabolic syndrome but do not have diabetes.
SeoulAges Any age - NCT06500078Recruiting
Intermittent Diet for Heart Health in Kids
This study tests whether a special diet pattern (eating less at certain times) can improve heart health and blood sugar in school-aged children. It's for children who are overweight or have early signs of diabetes or heart risks.
ShanghaiAges 7–18 - NCT03530852Recruiting
RELIZORB test for children needing tube feeding and IV nutrition
This study tests whether RELIZORB helps children with short bowel syndrome (SBS), who rely on IV nutrition (and also tube feeding), absorb fats better. It is an open-label study over 90 days, meaning everyone gets the study treatment and outcomes are compared over time.
Los Angeles, CaliforniaAges 2–18 - NCT03874052RecruitingPhase 1
Ruxolitinib plus venetoclax and azacitidine for relapsed AML
This early-phase study tests a combination of ruxolitinib with venetoclax, with or without azacitidine, for adults whose acute myeloid leukemia (AML) has come back or does not respond to treatment. It may help by stopping cancer cells from growing and improving blood counts, with the exact plan guided by the study arm you’re assigned to.
Columbus, OhioAges 18 years+ - NCT07595926Recruiting
Proper Height Measurement in Ventilator Patients with Lung Injury
This study examines whether the way doctors measure height in sedated patients on breathing machines affects lung protection. Researchers will compare different measurement methods to see which one helps prevent breathing-machine-related lung injury in patients with severe lung failure (ARDS).
AmiensAges 18 years+ - NCT07686601Enrolling by invitation
Shockwave therapy for belly fat
This study tests whether a sound-wave device (shockwave therapy) applied to your belly can help shrink fat and improve body measurements. It is for adults who have stubborn belly fat and are otherwise healthy.
Shibīn al Kawm, MenofyiaAges 18 years+ - NCT07688694Enrolling by invitation
Testing a legume-based supplement for blood sugar control
This study tests a supplement made from legume seed coats that may help control blood sugar. It is open to healthy adults, people at risk for diabetes, or those already diagnosed with type 2 diabetes.
Mysore, KarnatakaAges 20–60 - NCT07664358Recruiting
Predicting lung injury after traumatic brain injury
This study looks at whether a simple blood test measuring fibrinogen and albumin levels can help predict if someone with a traumatic brain injury will develop a serious lung condition called acute respiratory distress syndrome (ARDS). It may help doctors identify patients who need extra monitoring and care.
Tanta, Gharbia GovernorateAges 18 years+ - NCT06789445RecruitingPhase 1/Phase 2
Cell therapy for inherited retinal disease (CLARICO)
This study tests a new cell therapy (OpCT-001) for adults with inherited retinal diseases that affect the light-sensing cells. It aims to see if the treatment is safe and possibly helps improve vision.
Los Angeles, CaliforniaAges 18 years+ - NCT07399730Recruiting
Study of ravulizumab outcomes in Polish aHUS patients
This study looks at how well patients with aHUS in Poland are doing after treatment with ravulizumab (Ultomiris). It is for people who have already received this drug through the national program and agree to share their health information.
GdanskAges 18 years+ - NCT05635747Enrolling by invitation
90-day follow-up study for children using RELiZORB
This study follows children who are already taking RELiZORB to see how it’s going over time and whether it remains safe and tolerable, with effects on nutrient absorption. It doesn’t change treatment—it mainly looks at outcomes during the next 90 days.
Los Angeles, CaliforniaAges 2–18 - NCT06710002Recruiting
Home program for sexual pain in menopause
This trial tests a home-based therapy program (telerehabilitation) designed to reduce pain during sex and improve sexual function in menopausal women. The program involves exercises and guidance you can do from home without needing to visit a clinic.
Barcelona, SpainAges 45–65 - NCT06710067Recruiting
Urine chemicals for diagnosing disease
This study looks at chemicals in urine to help find new ways to diagnose diseases. You give one urine sample and answer a few questions—no treatment or long-term follow-up needed.
Encinitas, CaliforniaAges 18 years+ - NCT06714409Recruiting
Ultrasound-guided fluid removal in hospitalized heart failure
This study tests whether using ultrasound-guided treatment to reduce fluid buildup in the body can help people hospitalized for worsening heart failure feel better faster. It's for adults admitted with heart failure and high BNP levels.
OsloAges 18 years+ - NCT06715046Recruiting
Blood DNA test after stem cell transplant
This study checks if looking at DNA in your blood can help doctors see how well your stem cell transplant is working and catch any problems early. It is for people with blood cancers getting a transplant from a donor.
Milan, MilanAges 18 years+ - NCT06715787Recruiting
Perinatal support program for pregnant people
This trial tests a support program for pregnant individuals who qualify for certain food assistance benefits. It aims to see if the program helps with pregnancy and infant health.
Los Angeles, CaliforniaAges 18 years+ - NCT06718894Recruiting
New treatment strategy for primary podocytopathies
This trial is testing a new treatment approach for people with certain kidney diseases called podocytopathies (like FSGS and MCD). It may help if you have active disease, even after a kidney transplant, or if you have another type of kidney inflammation.
MilanAges Any age - NCT06719232Recruiting
Testing a new way to give bladder treatment without a catheter
This study tests a catheter-free method for delivering medication directly into the bladder. It may help patients with bladder pain, recurrent infections, bladder cancer, or cystitis after radiation or chemotherapy.
BudapestAges 18–80 - NCT06719830Recruiting
Finding the exact spot of a heart extra wire
This study looks at a new way to figure out exactly where a tiny extra electrical wire in your heart (called a septal accessory pathway) is located, to help guide the procedure that fixes it. It might help make the treatment more precise and safe.
Asyut, Asyut GovernorateAges Any age - NCT06720844Recruiting
Precocious puberty and related brain conditions study
This study looks at children with central precocious puberty (early puberty that starts in the brain) to see how often it's linked with other developmental issues. It compares how these children develop and respond to treatment.
Bologna, BolgonaAges Up to 18 years - NCT06721624Recruiting
Natural approaches for IBS: a research study
This study observes how naturopathic treatments help people with Irritable Bowel Syndrome (IBS) or IBS-like symptoms. It aims to understand what works in real-world care.
Portland, OregonAges 18 years+ - NCT06725511Recruiting
Wellness program for employees with metabolic syndrome
This study tests a wellness program designed for employees with metabolic syndrome, a cluster of conditions like high blood pressure and high blood sugar. The program aims to improve health through outreach and support.
Secaucus, New JerseyAges 21 years+
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,173 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.