Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,055 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06500078Recruiting
Intermittent Diet for Heart Health in Kids
This study tests whether a special diet pattern (eating less at certain times) can improve heart health and blood sugar in school-aged children. It's for children who are overweight or have early signs of diabetes or heart risks.
ShanghaiAges 7–18 - NCT06481943Recruiting
Testing a new heart scan for blocked arteries
This study tests a new magnetic heart scan (MCG) to see if it can better detect blocked arteries causing chest pain or heart attacks. It may help doctors decide the best treatment for you.
Rochester, MinnesotaAges 18 years+ - NCT06312956Recruiting
Sleep Apnea and Ventilotherapy: A Study Before and After Treatment
This trial studies how sleep apnea affects the body and brain before and after starting treatment with a breathing device (ventilotherapy). It aims to understand the benefits of early treatment for people with obstructive sleep apnea.
Piancavallo, VCOAges 20–60 - NCT06487247Recruiting
Home transfusion program for blood cancer patients
This trial offers red blood cell or platelet transfusions at home for people with blood cancer who are no longer responding to treatment. It aims to improve comfort and quality of life by avoiding hospital visits.
Boston, MassachusettsAges 18 years+ - NCT06480786Recruiting
Spinal cord stimulator for diabetic nerve and artery pain
This study tests if a spinal cord stimulator (a device that sends mild electrical pulses to the spine) can relieve severe leg pain caused by diabetic nerve damage and poor blood flow. It may help people who have not found enough relief from other treatments.
Omaha, NebraskaAges 19–89 - NCT06216821Recruiting
Personalized guide for timing blood-thinner reduction after a heart attack
This study tests whether a personalized score (OPT-CAD) can help decide the best time to stop or reduce blood-thinning medication in people who have had a heart attack and a stent placed. It aims to balance preventing future heart issues while lowering the risk of bleeding.
Shenyang, LiaoningAges 18–80 - NCT06472622RecruitingEarly Phase 1
Brain imaging study of pain and effort
This study uses brain scans to understand how people experience pain and effort. It compares healthy volunteers to people with ME/CFS to see if there are differences in brain activity.
Bethesda, MarylandAges 18–50 - NCT06465160RecruitingPhase 1
Study of MNV-201 for low-risk MDS with anemia
This study tests a new therapy called MNV-201 for people with low-risk myelodysplastic syndromes (MDS) who have anemia and need regular blood transfusions. The goal is to see if this treatment can help reduce or stop the need for transfusions.
Jerusalem, IsraelAges 18–100 - NCT06471751Recruiting
Breathing and throat muscle exercises for moderate sleep apnea
This trial tests whether strengthening your breathing and throat muscles can improve moderate sleep apnea. It aims to see if these exercises help reduce breathing pauses and improve sleep quality.
GrenobleAges 18 years+ - NCT06476795Recruiting
Grape pomace from chardonnay for heart and gut health in postmenopausal women
This study tests if consuming a powder made from chardonnay grape pomace (the leftover skins and seeds from winemaking) can improve gut and heart health in postmenopausal women. You may be a good fit if you are between 45-70, have gone through menopause, and have higher levels of blood fats called triglycerides.
Davis, CaliforniaAges 45–70 - NCT06469437Recruiting
Geriatric check for older adults with type 2 diabetes
This study looks at how a full health check for older adults with type 2 diabetes can help doctors choose the best treatment plan. It aims to improve care for people 60 and older.
Porto Alegre, Rio Grande do SulAges 60 years+ - NCT06471374Recruiting
Circadian rhythm in delayed sleep-wake phase disorder
This study looks at how your body's internal clock works in people with delayed sleep-wake phase disorder, especially those living at high altitudes. It aims to understand the causes of this sleep problem and may help find better treatments.
Boulder, ColoradoAges 16–40 - NCT06472765Enrolling by invitation
Study of the Vaginal Ecosystem in Healthy Women
This study looks at the natural balance of bacteria and other factors in the vagina of healthy women. It aims to learn more about what a healthy vaginal ecosystem looks like.
Fullerton, CaliforniaAges 18–89 - NCT06462287RecruitingPhase 2
Testing a substance P blocker for high blood pressure and sleep apnea
This study tests if a drug that blocks substance P can lower a hormone called aldosterone in people with both severe sleep apnea and high blood pressure. If you have these conditions, this trial may help find a new treatment option.
Rouen, FranceAges 18–75 - NCT06458374Recruiting
Heart Amyloidosis in Carpal Tunnel Surgery Patients
This study looks for people who had carpal tunnel surgery at Ålesund Hospital to check for a rare heart condition called ATTR amyloidosis. It aims to find the disease early and see how common it is.
Ålesund, Møre og RomsdalAges 50 years+ - NCT06446453Recruiting
Lung Ultrasound-Guided Surfactant For Preterm Infants
This study tests whether giving surfactant medication guided by a lung ultrasound, instead of by X-ray, helps preterm babies with breathing problems get better without needing a breathing tube. Babies in the study receive surfactant through a thin tube while still on non-invasive breathing support.
Hartford, ConnecticutAges birth–2 hours - NCT06451198RecruitingPhase 4
Indobufen vs aspirin after stent in older heart patients
This trial tests whether a blood thinner called indobufen works as well as aspirin for older people (65+) who have had a heart attack or unstable angina, received a drug-eluting stent, and are already taking two blood thinners. The goal is to find a safer or better option for long-term prevention.
Shanghai, Shanghai MunicipalityAges 65 years+ - NCT06450171Recruiting
Multi-cancer early detection test for people at high risk
This study tests a blood-based multi-cancer early detection (MCED) screening test in people with a high risk of cancer due to inherited gene changes or strong family history. The goal is to see if this test can find cancer early.
Boston, MassachusettsAges 22 years+ - NCT06453447Recruiting
Prednisone to prevent CRPS after wrist fracture surgery
This trial tests whether a short course of the steroid prednisone can prevent or reduce complex regional pain syndrome (CRPS) after wrist surgery. It is for people who had a broken wrist fixed with a plate and screws and have a higher chance of developing CRPS.
Vancouver, British ColumbiaAges 19 years+ - NCT06446947Recruiting
Blood markers for poor outcomes after sepsis in cancer surgery
This study looks at blood markers (epigenetics) to better understand why some people have a harder time recovering from a severe infection after major cancer surgery. The goal is to find early signs of poor outcomes in men aged 45–75 with post-surgery sepsis.
Marseille, Bouches du RhôneAges 45–75 - NCT06430697Recruiting
Paracetamol's effect on blood pressure in ICU patients
This trial measures how a common painkiller, paracetamol, affects blood pressure in intensive care patients. If you are in the ICU and your doctor has ordered paracetamol, this study may help understand its hemodynamic effects.
NiceAges 18 years+ - NCT06430554Recruiting
Personalized ventilation for ARDS patients on breathing machines
This trial tests a personalized ventilation method that adjusts how the breathing machine delivers air based on your lung's air and blood flow match. It aims to improve breathing for people with moderate to severe ARDS who are already on a ventilator and will be placed on their stomach.
Nanjing, JiangsuAges 18–85 - NCT06430528Recruiting
Osilodrostat and steroid replacement for Cushing syndrome
This trial tests a new approach, called 'block-and-replace', for treating Cushing syndrome. You will take osilodrostat to lower high cortisol levels, along with a glucocorticoid (a steroid) to replace what your body needs. This study may help control the disease if surgery hasn't worked or isn't an option.
Ann Arbor, MichiganAges 18–75 - NCT06439199Recruiting
Blood protein study in non-intensive chemotherapy for AML and MDS
This study looks at certain proteins in the blood (called FLT3 ligand and IL6) of people being treated for blood cancers like AML, MDS, or CMML. The goal is to understand how these proteins change during non-intensive chemotherapy, which may help doctors better personalize treatment.
Nantes, Loire-AtlantiqueAges 18–99
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,055 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.