Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,196 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07169136Recruiting
GLP-1 medicine for PCOS in teens with obesity
This trial tests if a medicine called a GLP-1 agonist (like semaglutide) can help with hormone and ovulation problems in adolescent girls with PCOS and obesity. It aims to improve irregular periods and other PCOS symptoms.
Jacksonville, FloridaAges 12–18 - NCT07170449Recruiting
Ultrasound test for carpal tunnel syndrome sensation
This study uses ultrasound to measure the size of a nerve in your wrist and compares it with your sense of touch. It aims to see if the ultrasound results match how much feeling you have lost in your hand.
Üsküdar, İ̇stanbulAges 18–65 - NCT07170527Recruiting
Metabolic signs, recovery, and physical function after ICU stay
This study looks at whether certain molecules in the blood (metabolic signatures) are linked to how well people recover physically after a serious illness requiring intensive care. By understanding these links, doctors might be able to better predict and support recovery.
Ede, GelderlandAges 18 years+ - NCT07176078Recruiting
Osteopathic care plus low-FODMAP diet for fibromyalgia and IBS
This trial tests whether adding osteopathic care (a hands-on therapy) to a low-FODMAP diet helps people with both fibromyalgia and irritable bowel syndrome feel better. It compares the diet alone to the diet plus osteopathic sessions.
Brussels, Brussels CapitalAges 18 years+ - NCT07177729Recruiting
Tick Bite Study – Understanding Immune Reactions
This study looks at how the body reacts to tick bites, specifically to understand alpha-gal syndrome—a condition that can cause allergic reactions to red meat. If you had a recent tick bite and can provide the tick, you may be able to help researchers learn more.
LuxembourgAges 18 years+ - NCT07179406Recruiting
Spinal cord stimulators for restless leg syndrome
This study tests whether a spinal cord stimulator can help people with restless leg syndrome (RLS). It compares people with RLS to healthy volunteers to see if the device reduces symptoms.
Birmingham, AlabamaAges 18 years+ - NCT07181018Recruiting
Metabolic syndrome study in Polish twins
This study looks at how metabolic syndrome (a cluster of conditions like high blood pressure, high blood sugar, and extra belly fat) runs in twins. It aims to better understand genetic and lifestyle factors, and may help you learn more about your own health risks.
Poznan, WielkopolskaAges 15–44 - NCT07181655Recruiting
Fasting, calorie cutting, and exercise for metabolic syndrome
This study tests if combining intermittent fasting, calorie reduction, and physical activity can help manage metabolic syndrome (a group of risk factors that increase your chance of heart disease, stroke, and diabetes). If you have at least three of five specific health issues (like belly fat, high blood pressure, or high blood sugar) and are an adult aged 18 or older, you may be able to join.
Serdang, SelangorAges 18–80 - NCT07181733Recruiting
BNP in Teens with Metabolic Syndrome
This study is looking at how heart function tests taken in the first month of life relate to metabolic syndrome (a group of conditions like high blood pressure and blood sugar) in teens. Researchers will use data already collected from when you were a baby.
Pavia, paviaAges 13–18 - NCT07182526RecruitingPhase 2
Quercetin or alpha lipoic acid for PCOS symptoms
This trial tests adding quercetin or alpha lipoic acid to standard PCOS care to see if they improve symptoms and blood markers. It may help women who have irregular periods or signs of excess androgens like acne.
Baghdad, KarkhAges 18 years+ - NCT07183774Recruiting
Does muscle loss affect shoulder tear patterns?
This study looks at whether sarcopenia (age-related muscle loss) affects the type of rotator cuff tear you have. You'll get a shoulder MRI to check your rotator cuff and muscle measurements.
Istanbul, ÜsküdarAges 40–75 - NCT07183878Recruiting
Venetoclax with BUCY conditioning for high-risk AML or MDS transplant
This trial tests whether adding venetoclax (a pill that targets cancer cells) to the standard chemotherapy regimen before a stem cell transplant improves outcomes for people with high-risk acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS). It is for patients aged 12–60 whose cancer has specific high-risk features and who have a matched donor.
Hangzhou, ZhejiangAges 12–60 - NCT07189936RecruitingPhase 2
Testing 2-HOBA for Immune Issues in Long COVID with POTS
This trial tests if a medication called 2-HOBA can help with ongoing immune system issues in people with Long COVID who also have POTS. It aims to reduce fatigue and other symptoms by calming overactive immune responses.
Nashville, TennesseeAges 18 years+ - NCT07194551Recruiting
Checking uterine cancer risk in Lynch syndrome with home sampling
This study is testing a new way to check for uterine cancer risk in people with Lynch syndrome. You would collect a vaginal sample yourself at home and fill out a health questionnaire, which may help catch warning signs early.
Vancouver, British ColumbiaAges 30 years+ - NCT07195253Recruiting
Down syndrome and sleep apnea study in infants
This study looks at mouth and face features and sleep apnea in 6-month-old infants with Down syndrome. It may help doctors understand and treat sleep problems better.
BronAges 5 months–6 months - NCT07199504RecruitingPhase 2/Phase 3
Dipyridamole for restless legs syndrome in dialysis patients
This trial tests if dipyridamole, a medication that affects blood flow, can help relieve restless legs syndrome (RLS) in people on hemodialysis. It may offer a new treatment option for RS related to kidney failure.
Chongqing, Chongqing MunicipalityAges 18–75 - NCT07202299Recruiting
Weaning preterm babies off high-frequency breathing machines
This trial tests two different ways to safely take preterm babies off a special breathing machine (HFOV). It aims to find which method works better for babies with breathing problems (respiratory distress syndrome).
Al MansurahAges Any age - NCT07208591RecruitingPhase 3
Test of an experimental drug for severe viral lung infection (ARDS)
This study tests an experimental drug (STSA-1002) for people with severe breathing problems caused by a viral infection. It aims to see if the drug can help improve oxygen levels and reduce the need for a breathing machine.
Beijing, Beijing MunicipalityAges 18–85 - NCT07208825Recruiting
Conservative care for complex regional pain syndrome
This study tests whether a conservative treatment plan can help people with complex regional pain syndrome (CRPS), a condition where pain lasts longer than expected after an injury. You may qualify if you have had CRPS symptoms for up to 5 years and are between ages 18 and 70.
Oulu, North OstrobothniaAges 18–70 - NCT07209462RecruitingPhase 2
MRM-3379 for Fragile X Syndrome in males
This trial tests an investigational medicine called MRM-3379 in males with Fragile X syndrome. It looks at how the medicine affects thinking and behavior over time.
Phoenix, ArizonaAges 13–45 - NCT07213063Recruiting
Creatine and HMB supplements for Down syndrome
This trial tests whether taking creatine and HMB supplements can improve muscle strength, reduce inflammation, and increase muscle mass in people with Down syndrome. It may help if you or your loved one can do basic physical tests like standing from a chair and do not have kidney disease or severe mobility issues.
Burgos, BurgosAges 18 years+ - NCT07214818RecruitingPhase 2/Phase 3
SGLT2 Inhibitors for Adult Primary Nephrotic Syndrome
This trial tests whether SGLT2 inhibitors (a type of diabetes medicine) can help adults with primary nephrotic syndrome, a kidney disease that causes protein leakage and swelling. It aims to see if the drug can protect kidney function and reduce protein loss.
Al Mansurah, Dakahlia GovernorateAges 18 years+ - NCT07219602RecruitingPhase 3
Study of obicetrapib and ezetimibe for diabetes and metabolic syndrome
This trial tests a combination medication (obicetrapib plus ezetimibe) taken daily to lower cholesterol and triglycerides in people with type 2 diabetes or metabolic syndrome who are already on standard cholesterol treatment. It may help reduce heart risks.
Sun City West, ArizonaAges 18 years+ - NCT07220239Recruiting
Menstrual cup for early cancer detection in Lynch syndrome
This study tests whether a menstrual cup can collect cells from the uterus to detect early endometrial cancer in women with Lynch syndrome. If you have Lynch syndrome and are due for a routine biopsy, you may be able to use a menstrual cup instead.
Boston, MassachusettsAges 18 years+
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,196 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.