Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,196 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07114913Recruiting
Carpal tunnel symptom location and pain study
This study looks at where carpal tunnel syndrome symptoms show up and how your body processes pain. By understanding this, doctors hope to find better ways to treat it.
Istanbul, UsküdarAges 18–65 - NCT07119255Recruiting
PRP acupuncture for long-term neck pain from muscle tightness
This study tests whether a treatment called platelet-rich plasma (PRP) acupuncture — using your own blood proteins — can reduce chronic neck pain caused by a common muscle condition. It may be a good option if you have had neck pain for months and want a non-surgical approach.
JakartaAges 18–59 - NCT07122505Recruiting
Mouth muscle therapy for sleep apnea in kids with Down or Prader-Willi syndrome
This study tests a therapy that strengthens mouth and tongue muscles to help children with Down or Prader-Willi syndrome who have mild obstructive sleep apnea. It aims to improve breathing during sleep without surgery or machines.
GhentAges 4–18 - NCT07123519RecruitingPhase 1
YTS109 cell therapy for hard-to-treat autoimmune diseases
This trial tests a new cell therapy called YTS109 for people with certain severe autoimmune diseases that have not responded to standard treatments, such as lupus, Sjögren's syndrome, systemic sclerosis, inflammatory myopathy, vasculitis, and antiphospholipid syndrome. The goal is to see if it can safely reduce disease activity.
TianjinAges 18–65 - NCT07133464Recruiting
CDH1 gene and BCDS syndrome registry
This registry studies people with changes in the CDH1 gene who may have blepharocheilodontic syndrome (BCDS). It collects information to better understand the condition and improve care.
Columbus, OhioAges Any age - NCT07134361Recruiting
Ultrasound study for carpal tunnel syndrome
This study uses hand ultrasound to evaluate carpal tunnel syndrome before and after surgery. It may help doctors understand how the wrist changes after treatment.
São Paulo, São PauloAges 18 years+ - NCT07135167RecruitingPhase 3
Epi-ON corneal crosslinking study for people with Down syndrome
This study tests a special light treatment for cornea problems in people with Down syndrome. It aims to strengthen the front of the eye and may help prevent vision loss.
Atlanta, GeorgiaAges 8 years+ - NCT07135752Recruiting
Comparing digital tests in people with early MS or MRI signs
This trial studies whether digital tests can detect early changes in people with radiologically isolated syndrome (RIS) or multiple sclerosis (MS) who have normal neurological exams. It may help identify subtle symptoms earlier.
NiceAges 18–60 - NCT07139626Recruiting
Biomarker study for heart and kidney health
This study looks for blood markers that may predict heart and kidney problems in people with stable chronic heart failure. If you have heart failure and are willing to give blood samples, you may help researchers better understand and manage this condition.
Nantong, JiangsuAges 18–75 - NCT07144631Recruiting
Nerve stimulation for restless legs in pregnancy
This trial tests if a small nerve stimulation device can safely and effectively reduce restless legs symptoms in pregnant people. If you are between 21 and 26 weeks pregnant with a confirmed diagnosis of restless legs syndrome (RLS), you may be eligible.
Providence, Rhode IslandAges 18 years+ - NCT07150013RecruitingPhase 1
Vorinostat for Rett syndrome safety study
This trial tests whether vorinostat is safe and helpful for girls and young women with Rett syndrome. Participants must have a confirmed MeCP2 mutation and be in a stable phase of the condition.
MedellínAges 6–21 - NCT07151248Recruiting
Earlobe stimulation for Gulf War veterans with chronic pain
This trial tests a mild electrical stimulation device (called CES) on the earlobe to see if it can reduce pain and improve brain function in veterans with Gulf War Illness. You will have brain scans and answer questions about your symptoms.
Atlanta, GeorgiaAges 40–80 - NCT07151274Recruiting
Ehlers-Danlos syndrome and women's gynecological health
This study uses an online questionnaire to explore how Ehlers-Danlos syndrome (EDS) may affect gynecological health. It compares women with EDS to those without, to better understand any differences.
RouenAges 18–50 - NCT07153276RecruitingPhase 4
Laser vs estrogen cream for vaginal dryness in Sjögren's
This trial compares two treatments for vaginal dryness in women with Sjögren's disease: a CO2 laser procedure versus a topical estrogen cream called promestriene. The goal is to see which option works better to relieve dryness and discomfort.
São Paulo, São PauloAges 30–65 - NCT07154134Recruiting
Blood markers in preterm babies with breathing problems
This study looks at two substances in the blood (endocan and copeptin) to see if they can help doctors understand breathing problems in premature babies. It may lead to better ways to care for these infants.
Tanta, El-GharbiaAges 6 months–8 months - NCT07157254RecruitingPhase 2
Study of GTX-102 for People with Angelman Syndrome
This study tests an experimental drug called GTX-102 for people with Angelman syndrome. It aims to see if the drug is safe and can help with symptoms. The trial includes different age groups and genetic types of Angelman syndrome.
Los Angeles, CaliforniaAges 1–64 - NCT07158723Recruiting
Protein and PCOS study for women
This trial tests how eating different types of protein affects women with PCOS. It may help you understand how your body responds to plant versus animal protein.
Fayetteville, ArkansasAges 18–50 - NCT07163338Recruiting
Antiphospholipid syndrome in older stroke patients
This study looks for a blood clotting disorder called antiphospholipid syndrome (APS) in people aged 65 and older who have had a stroke or a mini-stroke (TIA). The goal is to understand how common APS is in this group and if it affects recovery.
ReimsAges 65 years+ - NCT07163403RecruitingPhase 1
Preventing cancer in Lynch syndrome carriers with dendritic cell vaccine
This trial tests whether a personalized vaccine made from your own immune cells can help prevent cancer in people with Lynch syndrome. You must have no history of cancer and be willing to have regular colonoscopies.
Barcelona, BarcelonaAges 18 years+ - NCT07163780Recruiting
Home Therapy Program for Babies With Down Syndrome
This study tests a special therapy program called HEP (home early intervention program) for babies with Down syndrome. It looks at whether this program can help your baby's development.
Istanbul, BeykozAges 4 months–1 year - NCT07167368Recruiting
Exercise rehab for heart and kidney health
This trial tests whether a supervised exercise program can help people with heart failure and mild-to-moderate kidney problems. It might improve both your heart and kidney function.
Nantong, JiangsuAges 18–75 - NCT07167667Recruiting
Hand therapy for carpal tunnel syndrome
This study tests two types of hand therapy for carpal tunnel syndrome: shockwave therapy (5 sessions) or warm paraffin wax (10 sessions). It compares which one better reduces nerve thickening and your symptoms.
IstanbulAges 30–60 - NCT07167732Recruiting
CTNNB1 Syndrome Natural History Study
This study follows people with CTNNB1 syndrome over time to better understand the condition. It does not test any new treatment—just collects information to help future research.
SydneyAges Any age - NCT07168434RecruitingPhase 3
Yeast supplement for irritable bowel syndrome (IBS)
This trial tests if a yeast supplement called Saccharomyces boulardii can help people with irritable bowel syndrome (IBS), except for those with constipation as their main symptom. Participants take the supplement and see if their symptoms improve.
BragaAges 18–65
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,196 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.